LOCUS       NM_001354099            3952 bp    mRNA    linear   PRI 10-FEB-2025
DEFINITION  Homo sapiens proteasome activator subunit 3 interacting protein 1
            (PSME3IP1), transcript variant 23, mRNA.
ACCESSION   NM_001354099 XM_017023685
VERSION     NM_001354099.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3952)
  AUTHORS   Wu,X., Fang,Y., Gu,Y., Shen,H., Xu,Y., Xu,T., Shi,R., Xu,D.,
            Zhang,J., Leng,K., Shu,Y. and Ma,P.
  TITLE     Fat mass and obesity-associated protein (FTO) mediated m6A
            modification of circFAM192A promoted gastric cancer proliferation
            by suppressing SLC7A5 decay
  JOURNAL   Mol Biomed 5 (1), 11 (2024)
   PUBMED   38556586
  REMARK    GeneRIF: Fat mass and obesity-associated protein (FTO) mediated
            m[6]A modification of circFAM192A promoted gastric cancer
            proliferation by suppressing SLC7A5 decay.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3952)
  AUTHORS   Lipinski,K.A., Senn,K.A., Zeps,N.J. and Hoskins,A.A.
  TITLE     Biochemical and genetic evidence supports Fyv6 as a second-step
            splicing factor in Saccharomyces cerevisiae
  JOURNAL   RNA 29 (11), 1792-1802 (2023)
   PUBMED   37625852
REFERENCE   3  (bases 1 to 3952)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   4  (bases 1 to 3952)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (bases 1 to 3952)
  AUTHORS   Gao,X., Wang,Q., Wang,Y., Liu,J., Liu,S., Liu,J., Zhou,X., Zhou,L.,
            Chen,H., Pan,L., Chen,J., Wang,D., Zhang,Q., Shen,S., Xiao,Y.,
            Wu,Z., Cheng,Y., Chen,G., Kubra,S., Qin,J., Huang,L., Zhang,P.,
            Wang,C., Moses,R.E., Lonard,D.M., Malley,B.W.O., Fares,F.,
            Zhang,B., Li,X., Li,L. and Xiao,J.
  TITLE     The REGgamma inhibitor NIP30 increases sensitivity to chemotherapy
            in p53-deficient tumor cells
  JOURNAL   Nat Commun 11 (1), 3904 (2020)
   PUBMED   32764536
  REMARK    GeneRIF: The REGgamma inhibitor NIP30 increases sensitivity to
            chemotherapy in p53-deficient tumor cells.
            Erratum:[Nat Commun. 2020 Sep 23;11(1):4888. doi:
            10.1038/s41467-020-18767-0.. PMID: 32968062]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3952)
  AUTHORS   Jonik-Nowak,B., Menneteau,T., Fesquet,D., Baldin,V.,
            Bonne-Andrea,C., Mechali,F., Fabre,B., Boisguerin,P., de Rossi,S.,
            Henriquet,C., Pugniere,M., Ducoux-Petit,M., Burlet-Schiltz,O.,
            Lamond,A.I., Fort,P., Boulon,S., Bousquet,M.P. and Coux,O.
  TITLE     PIP30/FAM192A is a novel regulator of the nuclear proteasome
            activator PA28gamma
  JOURNAL   Proc Natl Acad Sci U S A 115 (28), E6477-E6486 (2018)
   PUBMED   29934401
  REMARK    GeneRIF: data show that PIP30 deeply affects PA28gamma interactions
            with cellular proteins, including the 20S proteasome, demonstrating
            that it is an important regulator of PA28gamma in cells and thus a
            new player in the control of the multiple functions of the
            proteasome within the nucleus.
REFERENCE   7  (bases 1 to 3952)
  AUTHORS   Waddell,D.S., Duffin,P.J., Haddock,A.N., Triplett,V.E.,
            Saredy,J.J., Kakareka,K.M. and Eldredge,J.T.
  TITLE     Isolation, expression analysis and characterization of
            NEFA-interacting nuclear protein 30 and RING finger and SPRY domain
            containing 1 in skeletal muscle
  JOURNAL   Gene 576 (1 Pt 2), 319-332 (2016)
   PUBMED   26497270
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009090.12.
            
            On May 31, 2019 this sequence version replaced NM_001354099.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: AL834421.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMEA1966682,
                                    SAMEA1968968 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-997               AC009090.12        81028-82024
            998-1348            AC009090.12        84726-85076
            1349-1490           AC009090.12        89709-89850
            1491-1589           AC009090.12        90704-90802
            1590-1711           AC009090.12        91206-91327
            1712-1845           AC009090.12        96352-96485
            1846-1910           AC009090.12        99513-99577
            1911-3952           AC009090.12        109071-111112
FEATURES             Location/Qualifiers
     source          1..3952
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q13"
     gene            1..3952
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="proteasome activator subunit 3 interacting protein
                     1"
                     /db_xref="GeneID:80011"
                     /db_xref="HGNC:HGNC:29856"
                     /db_xref="MIM:617766"
     exon            1..997
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1348
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1349..1490
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     CDS             1364..2128
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="isoform a is encoded by transcript variant 23;
                     NEFA-interacting nuclear protein NIP30; PA28G-interacting
                     protein; protein FAM192A; PA28G interacting protein 30kDa;
                     PSME3 interacting protein 30kDa; PSME3-interacting
                     protein; family with sequence similarity 192 member A"
                     /codon_start=1
                     /product="PSME3-interacting protein isoform a"
                     /protein_id="NP_001341028.1"
                     /db_xref="CCDS:CCDS42168.1"
                     /db_xref="GeneID:80011"
                     /db_xref="HGNC:HGNC:29856"
                     /db_xref="MIM:617766"
                     /translation="MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEEC
                     PEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEK
                     QRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHK
                     SSESGNSVKRLKPDPEPDDKNQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAY
                     SGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP"
     exon            1491..1589
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1711
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1712..1845
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1846..1910
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1911..3952
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2663..2668
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AGTAAA"
     polyA_site      2682
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="major polyA site"
     regulatory      2858..2863
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AATAAA"
     polyA_site      2885
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
     regulatory      3930..3935
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AATAAA"
     polyA_site      3952
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="major polyA site"
ORIGIN      
        1 agggaaatgg gtatctcctt atgttgcccg ggctggcctt gaactcctag gctcaagcag
       61 tcctccagtc tcagcctcct gagtaactgg gactgcgttt ttttgtttta ttttgttttt
      121 aatttggtct tgaagtggag ttatataggg tggggggagg gaggatggag tatgacttga
      181 ggtgtgggtt aggttctgaa gcgagcctag atgacaaaat agcttacaag caaagctacc
      241 cttgaaatct cagggaggca gcatgttaat tgtaggaata ccagtgttgc agaactctga
      301 catggccagt gtgatattgt aaaatacata tttggccttc atccctgtct cctgtggcat
      361 atgactccta taatccttga aatctccaaa atgattagtg tctttttata tgctaaggag
      421 ctgactgatg gctggcagcc cctaagtaac tttagcatgg gggctggtca cttgaaagac
      481 ccaggcagga ttagagggtt gggaccttca accaatgtcc aacctctggg gagaggagaa
      541 ggcagacgag ctgatgacca ccagcgtcac tggtttaatt agtcatgtct aagtaatgaa
      601 gcttccataa aaatccaaaa gactgggatt ggggagcttc tggataggtg gacatgagag
      661 gttcctggat gatggtgccc cagagagtgc atggaagctc tgtgcccttc ccacatgcct
      721 tgccctatgc attgcttcat ctgtatcctt tgtaatatgc ttttataata aaccagtata
      781 tgtaagtaaa gtgttcctct aagttcctct aagttctgtg aattggtcta gcaaattaat
      841 agaacctaag gagggggtca tgggaaccct gattaatagc cagttggtta gaactacagg
      901 taaaacaacc tgattcttgt ggttggtatc taaaatggag gctagtcttg tgggactcac
      961 ccctcaacct atgggatctg acgcggtctc catccagaat aaacagccat tggactcttc
     1021 aaacaaaaac gctgtctcca tcaagtactg ctttcgcagg ataagtgacc atttttaatc
     1081 agttgaaatt aacggaaagt agcagttatt tttgaaagat gacatcaatt atataatata
     1141 gtaaagagat ttaattttta gtcctttgtt tcttactgca caaattgtat ggcgtttgaa
     1201 tagaattccc atgatactga cacttcagca aatacttgct tgatggctac caatctctat
     1261 aacttacatt gcacagtacc taggaatatt catgtgagtt cattcctccc tgctcagatt
     1321 cttcagctcc tcgtggttgg tttattcaat tggttgtttc attatggatg gaggggatga
     1381 tggtaacctt attatcaaaa agaggtttgt gtctgaggca gaactagatg aacggcgcaa
     1441 aaggaggcaa gaagaatggg agaaagttcg aaaacctgaa gatccagaag aatgtccaga
     1501 ggaggtttat gaccctcgat ctctatatga aaggctacag gaacagaagg acaggaagca
     1561 gcaggagtac gaggaacagt tcaaattcaa aaacatggta agaggcttag atgaagatga
     1621 gaccaacttc cttgatgagg tttctcgaca gcaggaacta atagaaaagc aacgaagaga
     1681 agaagaactg aaagaactga aggaatacag aaataacctc aagaaggttg gaatttctca
     1741 agagaacaag aaggaagtgg aaaagaaact gactgtgaag cctatagaaa ccaagaacaa
     1801 gttctcccag gcgaagctgt tggcaggagc tgtgaagcat aagagctcag agagtggcaa
     1861 cagtgtgaaa agactgaaac cggaccctga gccagatgac aagaatcaag agccctcatc
     1921 ctgcaagtct ctcggaaaca cctccctgag tggcccctcc atccactgcc cctctgctgc
     1981 agtatgtatc ggcatcctcc caggcctggg tgcctactct gggagcagcg actccgagtc
     2041 cagctcagac agcgaaggca ccatcaatgc caccggaaag attgtctcct ccatcttccg
     2101 aaccaacacc ttcctcgagg ccccctagtt tctccgtccc tacacaggga gctcctcccc
     2161 aagggtagat cggaccgttc atgctgccta taggcattat gtccctcaaa aaaaaactcc
     2221 tttgcctgca tcctgtgtac aacatgacat ttttaaccaa tccaatctaa aaatgtgcca
     2281 gaatccacct gtggcccgaa tcgtgtttgg ttcctctttc tactccactg cagatgacca
     2341 aacctgtccc gctgccactt tcctcactga tattgggagg agggcaaggc ccagccgaag
     2401 ttccactaaa aatgccccag gagaataggc accggctggc ttgccaaagg gtttgggttt
     2461 tattgctttc tgttttttct tttcccgaca gcacaaagaa gtaagggcag ttattggaca
     2521 ggtgttattt aaacattcta ttgtaaatga atgtgttgtt tggttctact gcattgtgga
     2581 gcatgcgggg gaagagaact gacccaggta gtgaaatgga gcccttccct ggaactaacc
     2641 agtccttgat gttgtgtgac taagtaaaga tgataaaccc catctgctgg gggtgtcact
     2701 tcacactcgg catgcattgt gaaagctttc catacccttg gccattccct ctctcctctc
     2761 tctccaaccc catttatgca ggaagggact gctaacaaga acgcttccat ctcaaacctt
     2821 ttctctgcct gggaaattat tttatgtttg tttttgaaat aaaggattta gtttaagatt
     2881 ctaaatttta gagaaacaaa cgtaggcctt gtttactaat agccagacat cagaactgca
     2941 ggtaggtatg ttaatgagat gacttatttc tggcagctcc tggaatccta atattgtaaa
     3001 tgagtgggac acacttgcat attgtgacca ttctattgag gcccttctct gtttaatgca
     3061 tattatactt gtgcttttaa ctgtggaatc tatttctaac ctaaaggtgc tgccctagta
     3121 cttttctttg ctgcctctgc tgctcttttt cctttccaaa cagcaactct gaggccatga
     3181 gcagccaaaa actagaggta ctgctccacc tcgtctcata aagggaaacg ggctcatccc
     3241 ttggattctg gaggagggag agggagatgg tgtggaggcc tcgaggacag agatagacat
     3301 gagctttgac aacaatctgt aggctctcct gctttagaat aagcatgtac cattctttat
     3361 ccattcccct tattcctaca tcaattgttt ttactttctt gggtgtgaga ctgagtgaga
     3421 cacacacaaa atgtgttgac actgtgatgc cggcaggcag agcagctact gactttgaac
     3481 atgggcagag aggcccctgg atctcatcca gcccactcct tttccccttc cagtacagtg
     3541 acactctggt gcccattggc agatggcgac ttccctgcac ccataactga tgctttgtga
     3601 attcttcctc cttttcagaa ctactctgtg ctaattgttc tgccagtatg ggcgcatcag
     3661 ctccatcctg acaaacaaga catttaggta aaactttgta ggcaccttct gcttctctgc
     3721 ttcattgttc ctgtgatagt cctgttgtta ttacagcatg tacccaaaac agcctcacat
     3781 tgttacagga ggcaggccag gacatcaaag tcatcatctt tatgtggcat gactcttaag
     3841 aggccattac tgtatctcat ggcctcttga tgtggaaaga agttgacaga gggttgcagg
     3901 gtttaaaaac atccattaac atgaaagcta ataaacctgt cagagaacaa ga
//
