LOCUS       NM_001354088            3174 bp    mRNA    linear   PRI 10-FEB-2025
DEFINITION  Homo sapiens proteasome activator subunit 3 interacting protein 1
            (PSME3IP1), transcript variant 11, mRNA.
ACCESSION   NM_001354088 XM_017023684
VERSION     NM_001354088.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3174)
  AUTHORS   Wu,X., Fang,Y., Gu,Y., Shen,H., Xu,Y., Xu,T., Shi,R., Xu,D.,
            Zhang,J., Leng,K., Shu,Y. and Ma,P.
  TITLE     Fat mass and obesity-associated protein (FTO) mediated m6A
            modification of circFAM192A promoted gastric cancer proliferation
            by suppressing SLC7A5 decay
  JOURNAL   Mol Biomed 5 (1), 11 (2024)
   PUBMED   38556586
  REMARK    GeneRIF: Fat mass and obesity-associated protein (FTO) mediated
            m[6]A modification of circFAM192A promoted gastric cancer
            proliferation by suppressing SLC7A5 decay.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3174)
  AUTHORS   Lipinski,K.A., Senn,K.A., Zeps,N.J. and Hoskins,A.A.
  TITLE     Biochemical and genetic evidence supports Fyv6 as a second-step
            splicing factor in Saccharomyces cerevisiae
  JOURNAL   RNA 29 (11), 1792-1802 (2023)
   PUBMED   37625852
REFERENCE   3  (bases 1 to 3174)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   4  (bases 1 to 3174)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (bases 1 to 3174)
  AUTHORS   Gao,X., Wang,Q., Wang,Y., Liu,J., Liu,S., Liu,J., Zhou,X., Zhou,L.,
            Chen,H., Pan,L., Chen,J., Wang,D., Zhang,Q., Shen,S., Xiao,Y.,
            Wu,Z., Cheng,Y., Chen,G., Kubra,S., Qin,J., Huang,L., Zhang,P.,
            Wang,C., Moses,R.E., Lonard,D.M., Malley,B.W.O., Fares,F.,
            Zhang,B., Li,X., Li,L. and Xiao,J.
  TITLE     The REGgamma inhibitor NIP30 increases sensitivity to chemotherapy
            in p53-deficient tumor cells
  JOURNAL   Nat Commun 11 (1), 3904 (2020)
   PUBMED   32764536
  REMARK    GeneRIF: The REGgamma inhibitor NIP30 increases sensitivity to
            chemotherapy in p53-deficient tumor cells.
            Erratum:[Nat Commun. 2020 Sep 23;11(1):4888. doi:
            10.1038/s41467-020-18767-0.. PMID: 32968062]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3174)
  AUTHORS   Jonik-Nowak,B., Menneteau,T., Fesquet,D., Baldin,V.,
            Bonne-Andrea,C., Mechali,F., Fabre,B., Boisguerin,P., de Rossi,S.,
            Henriquet,C., Pugniere,M., Ducoux-Petit,M., Burlet-Schiltz,O.,
            Lamond,A.I., Fort,P., Boulon,S., Bousquet,M.P. and Coux,O.
  TITLE     PIP30/FAM192A is a novel regulator of the nuclear proteasome
            activator PA28gamma
  JOURNAL   Proc Natl Acad Sci U S A 115 (28), E6477-E6486 (2018)
   PUBMED   29934401
  REMARK    GeneRIF: data show that PIP30 deeply affects PA28gamma interactions
            with cellular proteins, including the 20S proteasome, demonstrating
            that it is an important regulator of PA28gamma in cells and thus a
            new player in the control of the multiple functions of the
            proteasome within the nucleus.
REFERENCE   7  (bases 1 to 3174)
  AUTHORS   Waddell,D.S., Duffin,P.J., Haddock,A.N., Triplett,V.E.,
            Saredy,J.J., Kakareka,K.M. and Eldredge,J.T.
  TITLE     Isolation, expression analysis and characterization of
            NEFA-interacting nuclear protein 30 and RING finger and SPRY domain
            containing 1 in skeletal muscle
  JOURNAL   Gene 576 (1 Pt 2), 319-332 (2016)
   PUBMED   26497270
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009090.12.
            
            On May 31, 2019 this sequence version replaced NM_001354088.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: AL834421.1 [ECO:0000331]
            RNAseq introns       :: mixed sample support SAMEA1965299,
                                    SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-219               AC009090.12        77539-77757
            220-570             AC009090.12        84726-85076
            571-712             AC009090.12        89709-89850
            713-811             AC009090.12        90704-90802
            812-933             AC009090.12        91206-91327
            934-1067            AC009090.12        96352-96485
            1068-1132           AC009090.12        99513-99577
            1133-3174           AC009090.12        109071-111112
FEATURES             Location/Qualifiers
     source          1..3174
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q13"
     gene            1..3174
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="proteasome activator subunit 3 interacting protein
                     1"
                     /db_xref="GeneID:80011"
                     /db_xref="HGNC:HGNC:29856"
                     /db_xref="MIM:617766"
     exon            1..219
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            220..570
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            571..712
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     CDS             586..1350
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="isoform a is encoded by transcript variant 11;
                     NEFA-interacting nuclear protein NIP30; PA28G-interacting
                     protein; protein FAM192A; PA28G interacting protein 30kDa;
                     PSME3 interacting protein 30kDa; PSME3-interacting
                     protein; family with sequence similarity 192 member A"
                     /codon_start=1
                     /product="PSME3-interacting protein isoform a"
                     /protein_id="NP_001341017.1"
                     /db_xref="CCDS:CCDS42168.1"
                     /db_xref="GeneID:80011"
                     /db_xref="HGNC:HGNC:29856"
                     /db_xref="MIM:617766"
                     /translation="MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEEC
                     PEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEK
                     QRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHK
                     SSESGNSVKRLKPDPEPDDKNQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAY
                     SGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP"
     exon            713..811
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            812..933
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1067
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1132
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..3174
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1885..1890
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AGTAAA"
     polyA_site      1904
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="major polyA site"
     regulatory      2080..2085
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AATAAA"
     polyA_site      2107
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
     regulatory      3152..3157
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AATAAA"
     polyA_site      3174
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="major polyA site"
ORIGIN      
        1 attgtggcgg tgaggaacag gaagccctga agggtcaaaa gaaatacaaa agcaaaggct
       61 attttctttt tttttttctt tctttcattc attccttcct ctgtttcttt ctttcttcct
      121 ttcatttttt tttctttttt aagagcgagc ggctctgcgg tggcggtttg gggtgggcgc
      181 cgccgaggtg aggtcgtctc gcctcccgcg cgccggtaga ataaacagcc attggactct
      241 tcaaacaaaa acgctgtctc catcaagtac tgctttcgca ggataagtga ccatttttaa
      301 tcagttgaaa ttaacggaaa gtagcagtta tttttgaaag atgacatcaa ttatataata
      361 tagtaaagag atttaatttt tagtcctttg tttcttactg cacaaattgt atggcgtttg
      421 aatagaattc ccatgatact gacacttcag caaatacttg cttgatggct accaatctct
      481 ataacttaca ttgcacagta cctaggaata ttcatgtgag ttcattcctc cctgctcaga
      541 ttcttcagct cctcgtggtt ggtttattca attggttgtt tcattatgga tggaggggat
      601 gatggtaacc ttattatcaa aaagaggttt gtgtctgagg cagaactaga tgaacggcgc
      661 aaaaggaggc aagaagaatg ggagaaagtt cgaaaacctg aagatccaga agaatgtcca
      721 gaggaggttt atgaccctcg atctctatat gaaaggctac aggaacagaa ggacaggaag
      781 cagcaggagt acgaggaaca gttcaaattc aaaaacatgg taagaggctt agatgaagat
      841 gagaccaact tccttgatga ggtttctcga cagcaggaac taatagaaaa gcaacgaaga
      901 gaagaagaac tgaaagaact gaaggaatac agaaataacc tcaagaaggt tggaatttct
      961 caagagaaca agaaggaagt ggaaaagaaa ctgactgtga agcctataga aaccaagaac
     1021 aagttctccc aggcgaagct gttggcagga gctgtgaagc ataagagctc agagagtggc
     1081 aacagtgtga aaagactgaa accggaccct gagccagatg acaagaatca agagccctca
     1141 tcctgcaagt ctctcggaaa cacctccctg agtggcccct ccatccactg cccctctgct
     1201 gcagtatgta tcggcatcct cccaggcctg ggtgcctact ctgggagcag cgactccgag
     1261 tccagctcag acagcgaagg caccatcaat gccaccggaa agattgtctc ctccatcttc
     1321 cgaaccaaca ccttcctcga ggccccctag tttctccgtc cctacacagg gagctcctcc
     1381 ccaagggtag atcggaccgt tcatgctgcc tataggcatt atgtccctca aaaaaaaact
     1441 cctttgcctg catcctgtgt acaacatgac atttttaacc aatccaatct aaaaatgtgc
     1501 cagaatccac ctgtggcccg aatcgtgttt ggttcctctt tctactccac tgcagatgac
     1561 caaacctgtc ccgctgccac tttcctcact gatattggga ggagggcaag gcccagccga
     1621 agttccacta aaaatgcccc aggagaatag gcaccggctg gcttgccaaa gggtttgggt
     1681 tttattgctt tctgtttttt cttttcccga cagcacaaag aagtaagggc agttattgga
     1741 caggtgttat ttaaacattc tattgtaaat gaatgtgttg tttggttcta ctgcattgtg
     1801 gagcatgcgg gggaagagaa ctgacccagg tagtgaaatg gagcccttcc ctggaactaa
     1861 ccagtccttg atgttgtgtg actaagtaaa gatgataaac cccatctgct gggggtgtca
     1921 cttcacactc ggcatgcatt gtgaaagctt tccataccct tggccattcc ctctctcctc
     1981 tctctccaac cccatttatg caggaaggga ctgctaacaa gaacgcttcc atctcaaacc
     2041 ttttctctgc ctgggaaatt attttatgtt tgtttttgaa ataaaggatt tagtttaaga
     2101 ttctaaattt tagagaaaca aacgtaggcc ttgtttacta atagccagac atcagaactg
     2161 caggtaggta tgttaatgag atgacttatt tctggcagct cctggaatcc taatattgta
     2221 aatgagtggg acacacttgc atattgtgac cattctattg aggcccttct ctgtttaatg
     2281 catattatac ttgtgctttt aactgtggaa tctatttcta acctaaaggt gctgccctag
     2341 tacttttctt tgctgcctct gctgctcttt ttcctttcca aacagcaact ctgaggccat
     2401 gagcagccaa aaactagagg tactgctcca cctcgtctca taaagggaaa cgggctcatc
     2461 ccttggattc tggaggaggg agagggagat ggtgtggagg cctcgaggac agagatagac
     2521 atgagctttg acaacaatct gtaggctctc ctgctttaga ataagcatgt accattcttt
     2581 atccattccc cttattccta catcaattgt ttttactttc ttgggtgtga gactgagtga
     2641 gacacacaca aaatgtgttg acactgtgat gccggcaggc agagcagcta ctgactttga
     2701 acatgggcag agaggcccct ggatctcatc cagcccactc cttttcccct tccagtacag
     2761 tgacactctg gtgcccattg gcagatggcg acttccctgc acccataact gatgctttgt
     2821 gaattcttcc tccttttcag aactactctg tgctaattgt tctgccagta tgggcgcatc
     2881 agctccatcc tgacaaacaa gacatttagg taaaactttg taggcacctt ctgcttctct
     2941 gcttcattgt tcctgtgata gtcctgttgt tattacagca tgtacccaaa acagcctcac
     3001 attgttacag gaggcaggcc aggacatcaa agtcatcatc tttatgtggc atgactctta
     3061 agaggccatt actgtatctc atggcctctt gatgtggaaa gaagttgaca gagggttgca
     3121 gggtttaaaa acatccatta acatgaaagc taataaacct gtcagagaac aaga
//
