LOCUS       NM_001354084            3170 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens proteasome activator subunit 3 interacting protein 1
            (PSME3IP1), transcript variant 7, mRNA.
ACCESSION   NM_001354084 XM_017023692
VERSION     NM_001354084.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3170)
  AUTHORS   Wu,X., Fang,Y., Gu,Y., Shen,H., Xu,Y., Xu,T., Shi,R., Xu,D.,
            Zhang,J., Leng,K., Shu,Y. and Ma,P.
  TITLE     Fat mass and obesity-associated protein (FTO) mediated m6A
            modification of circFAM192A promoted gastric cancer proliferation
            by suppressing SLC7A5 decay
  JOURNAL   Mol Biomed 5 (1), 11 (2024)
   PUBMED   38556586
  REMARK    GeneRIF: Fat mass and obesity-associated protein (FTO) mediated
            m[6]A modification of circFAM192A promoted gastric cancer
            proliferation by suppressing SLC7A5 decay.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3170)
  AUTHORS   Lipinski,K.A., Senn,K.A., Zeps,N.J. and Hoskins,A.A.
  TITLE     Biochemical and genetic evidence supports Fyv6 as a second-step
            splicing factor in Saccharomyces cerevisiae
  JOURNAL   RNA 29 (11), 1792-1802 (2023)
   PUBMED   37625852
REFERENCE   3  (bases 1 to 3170)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   4  (bases 1 to 3170)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (bases 1 to 3170)
  AUTHORS   Gao,X., Wang,Q., Wang,Y., Liu,J., Liu,S., Liu,J., Zhou,X., Zhou,L.,
            Chen,H., Pan,L., Chen,J., Wang,D., Zhang,Q., Shen,S., Xiao,Y.,
            Wu,Z., Cheng,Y., Chen,G., Kubra,S., Qin,J., Huang,L., Zhang,P.,
            Wang,C., Moses,R.E., Lonard,D.M., Malley,B.W.O., Fares,F.,
            Zhang,B., Li,X., Li,L. and Xiao,J.
  TITLE     The REGgamma inhibitor NIP30 increases sensitivity to chemotherapy
            in p53-deficient tumor cells
  JOURNAL   Nat Commun 11 (1), 3904 (2020)
   PUBMED   32764536
  REMARK    GeneRIF: The REGgamma inhibitor NIP30 increases sensitivity to
            chemotherapy in p53-deficient tumor cells.
            Erratum:[Nat Commun. 2020 Sep 23;11(1):4888. doi:
            10.1038/s41467-020-18767-0.. PMID: 32968062]
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3170)
  AUTHORS   Jonik-Nowak,B., Menneteau,T., Fesquet,D., Baldin,V.,
            Bonne-Andrea,C., Mechali,F., Fabre,B., Boisguerin,P., de Rossi,S.,
            Henriquet,C., Pugniere,M., Ducoux-Petit,M., Burlet-Schiltz,O.,
            Lamond,A.I., Fort,P., Boulon,S., Bousquet,M.P. and Coux,O.
  TITLE     PIP30/FAM192A is a novel regulator of the nuclear proteasome
            activator PA28gamma
  JOURNAL   Proc Natl Acad Sci U S A 115 (28), E6477-E6486 (2018)
   PUBMED   29934401
  REMARK    GeneRIF: data show that PIP30 deeply affects PA28gamma interactions
            with cellular proteins, including the 20S proteasome, demonstrating
            that it is an important regulator of PA28gamma in cells and thus a
            new player in the control of the multiple functions of the
            proteasome within the nucleus.
REFERENCE   7  (bases 1 to 3170)
  AUTHORS   Waddell,D.S., Duffin,P.J., Haddock,A.N., Triplett,V.E.,
            Saredy,J.J., Kakareka,K.M. and Eldredge,J.T.
  TITLE     Isolation, expression analysis and characterization of
            NEFA-interacting nuclear protein 30 and RING finger and SPRY domain
            containing 1 in skeletal muscle
  JOURNAL   Gene 576 (1 Pt 2), 319-332 (2016)
   PUBMED   26497270
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009090.12.
            
            On May 31, 2019 this sequence version replaced NM_001354084.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.59348.1,
                                           SRR1803615.248012.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-215               AC009090.12        77539-77753
            216-566             AC009090.12        84726-85076
            567-708             AC009090.12        89709-89850
            709-807             AC009090.12        90704-90802
            808-929             AC009090.12        91206-91327
            930-1063            AC009090.12        96352-96485
            1064-1128           AC009090.12        99513-99577
            1129-3170           AC009090.12        109071-111112
FEATURES             Location/Qualifiers
     source          1..3170
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16q13"
     gene            1..3170
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="proteasome activator subunit 3 interacting protein
                     1"
                     /db_xref="GeneID:80011"
                     /db_xref="HGNC:HGNC:29856"
                     /db_xref="MIM:617766"
     exon            1..215
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            216..566
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            567..708
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     CDS             582..1346
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="isoform a is encoded by transcript variant 7;
                     NEFA-interacting nuclear protein NIP30; PA28G-interacting
                     protein; protein FAM192A; PA28G interacting protein 30kDa;
                     PSME3 interacting protein 30kDa; PSME3-interacting
                     protein; family with sequence similarity 192 member A"
                     /codon_start=1
                     /product="PSME3-interacting protein isoform a"
                     /protein_id="NP_001341013.1"
                     /db_xref="CCDS:CCDS42168.1"
                     /db_xref="GeneID:80011"
                     /db_xref="HGNC:HGNC:29856"
                     /db_xref="MIM:617766"
                     /translation="MDGGDDGNLIIKKRFVSEAELDERRKRRQEEWEKVRKPEDPEEC
                     PEEVYDPRSLYERLQEQKDRKQQEYEEQFKFKNMVRGLDEDETNFLDEVSRQQELIEK
                     QRREEELKELKEYRNNLKKVGISQENKKEVEKKLTVKPIETKNKFSQAKLLAGAVKHK
                     SSESGNSVKRLKPDPEPDDKNQEPSSCKSLGNTSLSGPSIHCPSAAVCIGILPGLGAY
                     SGSSDSESSSDSEGTINATGKIVSSIFRTNTFLEAP"
     exon            709..807
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            808..929
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1063
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1064..1128
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..3170
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1881..1886
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AGTAAA"
     polyA_site      1900
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="major polyA site"
     regulatory      2076..2081
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AATAAA"
     polyA_site      2103
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
     regulatory      3148..3153
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="hexamer: AATAAA"
     polyA_site      3170
                     /gene="PSME3IP1"
                     /gene_synonym="C16orf94; CDA018; CDA10; FAM192A; NIP30;
                     PIP30"
                     /note="major polyA site"
ORIGIN      
        1 attgtggcgg tgaggaacag gaagccctga agggtcaaaa gaaatacaaa agcaaaggct
       61 attttctttt tttttttctt tctttcattc attccttcct ctgtttcttt ctttcttcct
      121 ttcatttttt tttctttttt aagagcgagc ggctctgcgg tggcggtttg gggtgggcgc
      181 cgccgaggtg aggtcgtctc gcctcccgcg cgccgaataa acagccattg gactcttcaa
      241 acaaaaacgc tgtctccatc aagtactgct ttcgcaggat aagtgaccat ttttaatcag
      301 ttgaaattaa cggaaagtag cagttatttt tgaaagatga catcaattat ataatatagt
      361 aaagagattt aatttttagt cctttgtttc ttactgcaca aattgtatgg cgtttgaata
      421 gaattcccat gatactgaca cttcagcaaa tacttgcttg atggctacca atctctataa
      481 cttacattgc acagtaccta ggaatattca tgtgagttca ttcctccctg ctcagattct
      541 tcagctcctc gtggttggtt tattcaattg gttgtttcat tatggatgga ggggatgatg
      601 gtaaccttat tatcaaaaag aggtttgtgt ctgaggcaga actagatgaa cggcgcaaaa
      661 ggaggcaaga agaatgggag aaagttcgaa aacctgaaga tccagaagaa tgtccagagg
      721 aggtttatga ccctcgatct ctatatgaaa ggctacagga acagaaggac aggaagcagc
      781 aggagtacga ggaacagttc aaattcaaaa acatggtaag aggcttagat gaagatgaga
      841 ccaacttcct tgatgaggtt tctcgacagc aggaactaat agaaaagcaa cgaagagaag
      901 aagaactgaa agaactgaag gaatacagaa ataacctcaa gaaggttgga atttctcaag
      961 agaacaagaa ggaagtggaa aagaaactga ctgtgaagcc tatagaaacc aagaacaagt
     1021 tctcccaggc gaagctgttg gcaggagctg tgaagcataa gagctcagag agtggcaaca
     1081 gtgtgaaaag actgaaaccg gaccctgagc cagatgacaa gaatcaagag ccctcatcct
     1141 gcaagtctct cggaaacacc tccctgagtg gcccctccat ccactgcccc tctgctgcag
     1201 tatgtatcgg catcctccca ggcctgggtg cctactctgg gagcagcgac tccgagtcca
     1261 gctcagacag cgaaggcacc atcaatgcca ccggaaagat tgtctcctcc atcttccgaa
     1321 ccaacacctt cctcgaggcc ccctagtttc tccgtcccta cacagggagc tcctccccaa
     1381 gggtagatcg gaccgttcat gctgcctata ggcattatgt ccctcaaaaa aaaactcctt
     1441 tgcctgcatc ctgtgtacaa catgacattt ttaaccaatc caatctaaaa atgtgccaga
     1501 atccacctgt ggcccgaatc gtgtttggtt cctctttcta ctccactgca gatgaccaaa
     1561 cctgtcccgc tgccactttc ctcactgata ttgggaggag ggcaaggccc agccgaagtt
     1621 ccactaaaaa tgccccagga gaataggcac cggctggctt gccaaagggt ttgggtttta
     1681 ttgctttctg ttttttcttt tcccgacagc acaaagaagt aagggcagtt attggacagg
     1741 tgttatttaa acattctatt gtaaatgaat gtgttgtttg gttctactgc attgtggagc
     1801 atgcggggga agagaactga cccaggtagt gaaatggagc ccttccctgg aactaaccag
     1861 tccttgatgt tgtgtgacta agtaaagatg ataaacccca tctgctgggg gtgtcacttc
     1921 acactcggca tgcattgtga aagctttcca tacccttggc cattccctct ctcctctctc
     1981 tccaacccca tttatgcagg aagggactgc taacaagaac gcttccatct caaacctttt
     2041 ctctgcctgg gaaattattt tatgtttgtt tttgaaataa aggatttagt ttaagattct
     2101 aaattttaga gaaacaaacg taggccttgt ttactaatag ccagacatca gaactgcagg
     2161 taggtatgtt aatgagatga cttatttctg gcagctcctg gaatcctaat attgtaaatg
     2221 agtgggacac acttgcatat tgtgaccatt ctattgaggc ccttctctgt ttaatgcata
     2281 ttatacttgt gcttttaact gtggaatcta tttctaacct aaaggtgctg ccctagtact
     2341 tttctttgct gcctctgctg ctctttttcc tttccaaaca gcaactctga ggccatgagc
     2401 agccaaaaac tagaggtact gctccacctc gtctcataaa gggaaacggg ctcatccctt
     2461 ggattctgga ggagggagag ggagatggtg tggaggcctc gaggacagag atagacatga
     2521 gctttgacaa caatctgtag gctctcctgc tttagaataa gcatgtacca ttctttatcc
     2581 attcccctta ttcctacatc aattgttttt actttcttgg gtgtgagact gagtgagaca
     2641 cacacaaaat gtgttgacac tgtgatgccg gcaggcagag cagctactga ctttgaacat
     2701 gggcagagag gcccctggat ctcatccagc ccactccttt tccccttcca gtacagtgac
     2761 actctggtgc ccattggcag atggcgactt ccctgcaccc ataactgatg ctttgtgaat
     2821 tcttcctcct tttcagaact actctgtgct aattgttctg ccagtatggg cgcatcagct
     2881 ccatcctgac aaacaagaca tttaggtaaa actttgtagg caccttctgc ttctctgctt
     2941 cattgttcct gtgatagtcc tgttgttatt acagcatgta cccaaaacag cctcacattg
     3001 ttacaggagg caggccagga catcaaagtc atcatcttta tgtggcatga ctcttaagag
     3061 gccattactg tatctcatgg cctcttgatg tggaaagaag ttgacagagg gttgcagggt
     3121 ttaaaaacat ccattaacat gaaagctaat aaacctgtca gagaacaaga
//
