LOCUS       NM_001002758            1238 bp    mRNA    linear   PRI 02-FEB-2024
DEFINITION  Homo sapiens PTPN13 like Y-linked 2 (PRY2), mRNA.
ACCESSION   NM_001002758
VERSION     NM_001002758.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1238)
  AUTHORS   Repping,S., van Daalen,S.K., Korver,C.M., Brown,L.G.,
            Marszalek,J.D., Gianotten,J., Oates,R.D., Silber,S., van der
            Veen,F., Page,D.C. and Rozen,S.
  TITLE     A family of human Y chromosomes has dispersed throughout northern
            Eurasia despite a 1.8-Mb deletion in the azoospermia factor c
            region
  JOURNAL   Genomics 83 (6), 1046-1052 (2004)
   PUBMED   15177557
REFERENCE   2  (bases 1 to 1238)
  AUTHORS   Skaletsky,H., Kuroda-Kawaguchi,T., Minx,P.J., Cordum,H.S.,
            Hillier,L., Brown,L.G., Repping,S., Pyntikova,T., Ali,J., Bieri,T.,
            Chinwalla,A., Delehaunty,A., Delehaunty,K., Du,H., Fewell,G.,
            Fulton,L., Fulton,R., Graves,T., Hou,S.F., Latrielle,P.,
            Leonard,S., Mardis,E., Maupin,R., McPherson,J., Miner,T., Nash,W.,
            Nguyen,C., Ozersky,P., Pepin,K., Rock,S., Rohlfing,T., Scott,K.,
            Schultz,B., Strong,C., Tin-Wollam,A., Yang,S.P., Waterston,R.H.,
            Wilson,R.K., Rozen,S. and Page,D.C.
  TITLE     The male-specific region of the human Y chromosome is a mosaic of
            discrete sequence classes
  JOURNAL   Nature 423 (6942), 825-837 (2003)
   PUBMED   12815422
REFERENCE   3  (bases 1 to 1238)
  AUTHORS   Lahn,B.T. and Page,D.C.
  TITLE     Functional coherence of the human Y chromosome
  JOURNAL   Science 278 (5338), 675-680 (1997)
   PUBMED   9381176
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC007359.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            Summary: This gene is located in the nonrecombining portion of the
            Y chromosome, and expressed specifically in testis. It encodes a
            protein which has a low degree of similarity to protein tyrosine
            phosphatase, non-receptor type 13. Two nearly identical copies of
            this gene exist within a palindromic region. This record represents
            the more centromeric copy. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874,
                              SAMEA2158188 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000303804.5/ ENSP00000303300.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-88                AC007359.3         63824-63911         c
            89-175              AC007359.3         63636-63722         c
            176-296             AC007359.3         52675-52795         c
            297-412             AC007359.3         49984-50099         c
            413-1238            AC007359.3         39660-40485         c
FEATURES             Location/Qualifiers
     source          1..1238
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="Y"
                     /map="Yq11.223"
     gene            1..1238
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /note="PTPN13 like Y-linked 2"
                     /db_xref="GeneID:442862"
                     /db_xref="HGNC:HGNC:21504"
                     /db_xref="MIM:400041"
     exon            1..88
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /inference="alignment:Splign:2.1.0"
     exon            89..175
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /inference="alignment:Splign:2.1.0"
     exon            176..296
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /inference="alignment:Splign:2.1.0"
     CDS             228..671
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /note="PTPN13-like, Y-linked, centromeric; testis-specific
                     PTP-BL-related protein on Y; testis-specific
                     PTP-BL-related Y protein"
                     /codon_start=1
                     /product="PTPN13-like protein, Y-linked"
                     /protein_id="NP_001002758.1"
                     /db_xref="CCDS:CCDS35482.1"
                     /db_xref="GeneID:442862"
                     /db_xref="HGNC:HGNC:21504"
                     /db_xref="MIM:400041"
                     /translation="MGATGLGFLLSWRQDNLNGTDCQGCNILYFSETTGSMCSELSLN
                     RGLEARRKKDLKDSFLWRYGKVGCISLPLREMTAWINPPQISEIFQGYHQRVHGADAL
                     SLQTNSLRSRLSSQCLGQSFLLRTLERGRGFRALGDICGHVHEED"
     exon            297..412
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /inference="alignment:Splign:2.1.0"
     exon            413..1238
                     /gene="PRY2"
                     /gene_synonym="PTPN13LY2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagaagagga gcacaccaca ccagaaacag acatcttgca gtgtttcact gtctcaacct
       61 tatctgcaca gtccgaggtc agtctgagag agcttctgag agacccagga tgaagggatg
      121 cagtgaggtc aagagcccaa ccttctttca ctgacaccca cctctaagga ctcagagaga
      181 catgaataaa atgggcctca acaatcccaa gagaccactc aaggacaatg ggagccactg
      241 ggcttggctt tctactttcc tggagacaag acaatttgaa tggcactgac tgccagggat
      301 gcaatatttt atacttctct gagactacgg ggagcatgtg ttctgaactt tccttgaaca
      361 gaggtcttga ggccagaagg aagaaggatc ttaaagactc atttctctgg agatatggga
      421 aggttggctg tatctcactt ccacttcgtg agatgaccgc ctggattaac ccaccccaaa
      481 tttcagagat tttccaaggc taccaccaga gggtgcacgg agctgatgca ctgagcctgc
      541 aaaccaactc tctgagaagc aggttatctt cacagtgcct cggacagagc ttccttctca
      601 ggacactcga gagaggccgt ggtttcaggg cacttgggga catctgtggc cacgttcatg
      661 aagaagacta agcctacttc atctcaggac ccgcccaaga gtggccgcgg ctttgggaca
      721 cctggggtcg ggtccaccat gaggataaaa cctccttctc ttctggacat gtccaggagt
      781 ggccgttgct acaagtcacc tggtgctacg accagggtga gaataaagac gtctcctcag
      841 gaccctccca ggagagtaca tggcattgag acatctggcg gccaagtgag gaaaagacac
      901 cctgtctgca gcacccagaa ctgaggaggg gcactgccct gggccttact tcccagccct
      961 ggcctccaat tctgacctta caaaagtgtc ccttgagtga ggcagtgacc acgcattgtc
     1021 acagctacca aagtgtggtt tgcagatgat ctgggcttgt ttctggcaga gattctggta
     1081 cagagaaagg agaggcgctg agtggaacca cgatgggctg aggccagggg agacatcgca
     1141 acctccaaca acactttttt tcatgcttta ataactcatt tttcttagag aactaaagta
     1201 gttgaaacaa tatagaaaca ttttttaagt aggcatat
//
