LOCUS       NM_001395501            1105 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens serine protease 41 (PRSS41), transcript variant 3,
            mRNA.
ACCESSION   NM_001395501
VERSION     NM_001395501.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Puente,X.S., Sanchez,L.M., Overall,C.M. and Lopez-Otin,C.
  TITLE     Human and mouse proteases: a comparative genomic approach
  JOURNAL   Nat Rev Genet 4 (7), 544-558 (2003)
   PUBMED   12838346
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092117.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000399677.5/ ENSP00000492058.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AC092117.4         189541-189619
            80-106              AC092117.4         189707-189733
            107-272             AC092117.4         190030-190195
            273-556             AC092117.4         190357-190640
            557-714             AC092117.4         195460-195617
            715-1105            AC092117.4         195985-196375
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.3"
     gene            1..1105
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /note="serine protease 41"
                     /db_xref="GeneID:360226"
                     /db_xref="HGNC:HGNC:30715"
     exon            1..79
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..933
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /EC_number="3.4.21.-"
                     /note="isoform 3 precursor is encoded by transcript
                     variant 3; testis-specific serine protease 1; putative
                     serine protease 41; protease, serine 41"
                     /codon_start=1
                     /product="serine protease 41 isoform 3 precursor"
                     /protein_id="NP_001382430.1"
                     /db_xref="CCDS:CCDS92090.1"
                     /db_xref="GeneID:360226"
                     /db_xref="HGNC:HGNC:30715"
                     /translation="MGARGALLLALLLARAGLGKPESQEEELLSEACGHREIHALVAG
                     GVESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHCFQKHYYPSEWTVQLGELTS
                     RPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTF
                     NFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQPSSRSMIWDS
                     MFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVYF
                     HWIRRVMSHSTPRPNPSQLLLLLALLWAP"
     exon            80..106
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /inference="alignment:Splign:2.1.0"
     exon            107..272
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /inference="alignment:Splign:2.1.0"
     exon            273..556
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /inference="alignment:Splign:2.1.0"
     exon            557..714
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /inference="alignment:Splign:2.1.0"
     exon            715..1105
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1083..1088
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /note="hexamer: AATAAA"
     polyA_site      1105
                     /gene="PRSS41"
                     /gene_synonym="TESSP1"
                     /note="major polyA site"
ORIGIN      
        1 gcgggagagg aggccatggg cgcgcgcggg gcgctgctgc tggcgctgct gctggctcgg
       61 gctggactcg ggaagccgga gtcgcaggag gaggagctgt tgtcagaggc ctgcggccac
      121 cgggaaattc acgcgctggt ggcgggcgga gtggagtccg cgcgcgggcg ctggccatgg
      181 caggccagcc tgcgcctgag gagacgccac cgatgtggag ggagcctgct cagccgccgc
      241 tgggtgctct cggctgcgca ctgcttccaa aagcactact atccctccga gtggacggtc
      301 cagctgggcg agctgacttc caggccaact ccttggaacc tgcgggccta cagcagtcgt
      361 tacaaagtgc aggacatcat tgtgaaccct gacgcacttg gggttttacg caatgacatt
      421 gccctgctga gactggcctc ttctgtcacc tacaatgcgt acatccagcc catttgcatc
      481 gagtcttcca ccttcaactt cgtgcaccgg ccggactgct gggtgaccgg ctgggggtta
      541 atcagcccca gtggcacacc tctgccacct ccttacaacc tccgggaagc acaggtcacc
      601 atcttaaaca acaccaggtg taattacctg tttgaacagc cctctagccg tagtatgatc
      661 tgggattcca tgttttgtgc tggtgctgag gatggcagtg tagacacctg caaaggtgac
      721 tcaggtggac ccttggtctg tgacaaggat ggactgtggt atcaggttgg aatcgtgagc
      781 tggggaatgg actgcggtca acccaatcgg cctggtgtct acaccaacat cagtgtgtac
      841 ttccactgga tccggagggt gatgtcccac agtacaccca ggccaaaccc ctcccagctg
      901 ttgctgctcc ttgccctgct gtgggctccc tgactcctgc agccattctg agtgcaccag
      961 aaactgtgag gctgcagtgg ggaccacagt attggctcac ctcctctggg ctgtgggcgc
     1021 ttcagggaca gggttgggac tgcctgctgg atcagattcc ggcccctttt gtctcgtttg
     1081 ctaataaata cgtgtgcatg ttcaa
//
