LOCUS       NM_001395643            2498 bp    mRNA    linear   PRI 06-AUG-2024
DEFINITION  Homo sapiens proline rich transmembrane protein 1B (PRRT1B),
            transcript variant 2, mRNA.
ACCESSION   NM_001395643
VERSION     NM_001395643.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2498)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL160276.21.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2142348
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000636672.2/ ENSP00000490857.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-118               AL160276.21        4297-4414
            119-591             AL160276.21        13331-13803
            592-735             AL160276.21        14844-14987
            736-2498            AL160276.21        16827-18589
FEATURES             Location/Qualifiers
     source          1..2498
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q34.13"
     gene            1..2498
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /note="proline rich transmembrane protein 1B"
                     /db_xref="GeneID:642515"
                     /db_xref="HGNC:HGNC:53642"
     exon            1..118
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..885
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /note="isoform 2 is encoded by transcript variant 2;
                     proline-rich transmembrane protein 1-like; dispanin
                     subfamily D member 2"
                     /codon_start=1
                     /product="proline rich transmembrane protein 1B isoform 2"
                     /protein_id="NP_001382572.1"
                     /db_xref="CCDS:CCDS94520.1"
                     /db_xref="GeneID:642515"
                     /db_xref="HGNC:HGNC:53642"
                     /translation="MEAGAGGAGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPAL
                     PQLPRRPRTLDEDGAPSEDGAAGGSEPAPEDAPAQAAGEAGPVSKAAAGGAPHIGFVG
                     EPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGA
                     AFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEARAA
                     LGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP"
     exon            119..591
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     exon            592..735
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     exon            736..2498
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2474..2479
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /note="hexamer: ATTAAA"
     polyA_site      2498
                     /gene="PRRT1B"
                     /gene_synonym="DSPD2; IFITMD8"
                     /note="major polyA site"
ORIGIN      
        1 aaacctgagc ccgcggcgca agcggagccg gcccgacggc aggcgccggg ccagggagcc
       61 gcgcagccct tgcagccgcc gcgggctcgg accatggagg caggagctgg aggggcaggg
      121 tccgacacga aagggggcgg cagccccgcc acccccgagg acccccggag ccccgcgaag
      181 cccgccgccc ccgaggatcc ccagatgccc gcgcagcccg cgctcccgca gctcccgcgc
      241 cgcccgcgga ccctggacga ggacggggcg cccagcgagg acggggccgc ggggggcagc
      301 gagcccgccc cggaggacgc cccggcccag gcggcgggcg aggccgggcc ggtttccaag
      361 gcggcggccg gcggcgcccc ccacatcggc ttcgttgggg agcccccgcc ctacgcgccg
      421 ccggacccca aggccgcgcc gctgctgtac ccgcccttcc cgcaggtgcc cgtggtcctg
      481 cagcccgcgc cgtctgcgct cttcccgccg cccgcccagc tctacccagc cgcgcccacg
      541 ccgcccgcgc tcttctcgcc gcccgccggg gccgccttcc ccttccccgt gtacaatggc
      601 ccgatggctg gcgtgccagg ccctgccacg gtggagcaca ggcccctgcc aaaggactac
      661 atgatggagt cagtgctggt gaccctcttc tgctgtctgc tcaccggtct catcgccatc
      721 gtctactccc acgaggcccg tgcagcactg ggcaggggtg acctggccca ggctgaggag
      781 gcctcgcgga aggcccgctc gctggtgctc ttcagcctgc tcttcggggt cttcgtgtct
      841 accagctggg tcatctacgt ggtggtggca ctctaccttc cctgaggctg tggctcctgc
      901 ggagatgccg gatgccggaa tgtccacgga aaactggccg ggccagaccc tttctctgga
      961 ctcagatccc tgccggtggc cagctcttgc ctgcagaggg aatctggggg ccagaagagg
     1021 gcaggcttgg cagccctcaa ctgacttgtg gctgggcctc agcctcctca gcctccacag
     1081 gtggcccact ggagcctcag tcagtgtcct aatccaaggt gtctccagag cccggcccca
     1141 gccgtgggac aggagcccac cagagcccca tttcccagga gcctcctctc aaggccttcc
     1201 tgggactcct cttgccttca tctgtgctct tgggaggcca tcgtagggac caaagccttc
     1261 tctgtcttca gagccatctg gaaggacact gcaacctccg ccccccgccc aacctccagc
     1321 ccagcttagg cgatcaggat gccagtatta cctttccctg cgggagagtg gagcatggtg
     1381 acttctggct ggttgttccc ctatcccttc cccatcccag gagacagggt ccctcatgct
     1441 gaccctacat ccagaaacca gggccactct gtctggtcaa tcaacagaaa gtgacacatc
     1501 cgtgcggagc ttcacactgc tactttgggg acacttcctg gctctcttcc agggccaatg
     1561 gcaacatctg tccacagttg ggctccaggg caccctaccc actcctctct gagatgctgt
     1621 tggcatagag gcagtgctgg caagaactac ccaatgacag aggatcagct gggtgctcgt
     1681 ttgatgagga ccgccctgac tggggagcac ttgcaccaag atccctcggc cagcctgtag
     1741 aaccgtacct atgactctgg catcagattc ctggcacccc agtcccacta gctgtggtcc
     1801 caagaatgaa cctgcatttt aacaagattc aaaaccattg cagaggccag gcgaggtggc
     1861 tcacacctgt aatcccagca gtttgggagg ccgaggtggg tggatcacct gagtcaggag
     1921 ttcaagacca acctggccaa catggcgaag tcctgtctct actaaaaata caaaaattag
     1981 ccgagtgtag tggcaggcgc ctgtaatcct agctactcgg gaggctgagg caggagaatt
     2041 gcttgaatcc gggaggcaga agttgcagtg agctgattgt gccactgcac tccagcctgg
     2101 gtgacagagt gagactctgc ctcaaaaaca aacaaccatt gcagacagag gaggaagggg
     2161 acccccagct gagccacaca atattgatag ctcaagctaa atcagttggt ttcagagcag
     2221 cctcggtgtg ctgcttacaa ccctggcacc aggggctgaa acaggagaat ggcccagccc
     2281 agcccagtcc ctcctccaga aagctggaga ggcaggcatg aggaagtaag tcatgagcag
     2341 cctggagact ctgtggattt ttgttcagta agcagggcct gaggttctgc atttctaata
     2401 agcttcccag tgatgctgaa gctggtactc aaaccaatag caaagtggga aattatcaaa
     2461 actactaaaa ggcattaaaa ccaggatcat gacatgga
//
