LOCUS       NM_001122716            1263 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens proline rich 32 (PRR32), mRNA.
ACCESSION   NM_001122716 XM_001719075 XM_001720449 XM_001720573
VERSION     NM_001122716.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1263)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1263)
  AUTHORS   Shtilbans,A., Choi,S.G., Fowkes,M.E., Khitrov,G., Shahbazi,M.,
            Ting,J., Zhang,W., Sun,Y., Sealfon,S.C. and Lange,D.J.
  TITLE     Differential gene expression in patients with amyotrophic lateral
            sclerosis
  JOURNAL   Amyotroph Lateral Scler 12 (4), 250-256 (2011)
   PUBMED   21375368
REFERENCE   3  (bases 1 to 1263)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
REFERENCE   4  (bases 1 to 1263)
  AUTHORS   Harrington,J.J., Sherf,B., Rundlett,S., Jackson,P.D., Perry,R.,
            Cain,S., Leventhal,C., Thornton,M., Ramachandran,R.,
            Whittington,J., Lerner,L., Costanzo,D., McElligott,K., Boozer,S.,
            Mays,R., Smith,E., Veloso,N., Klika,A., Hess,J., Cothren,K., Lo,K.,
            Offenbacher,J., Danzig,J. and Ducar,M.
  TITLE     Creation of genome-wide protein expression libraries using random
            activation of gene expression
  JOURNAL   Nat Biotechnol 19 (5), 440-445 (2001)
   PUBMED   11329013
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662896.9, R10182.1, BG200532.1 and CA433109.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_001122716.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279834.7649.1, R10182.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2158800, SAMEA2162946
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000371125.4/ ENSP00000360166.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                AL662896.9         51509-51543
            36-194              R10182.1           1-159
            195-761             BG200532.1         60-626
            762-1263            CA433109.1         16-517              c
FEATURES             Location/Qualifiers
     source          1..1263
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq25"
     gene            1..1263
                     /gene="PRR32"
                     /gene_synonym="CXorf64"
                     /note="proline rich 32"
                     /db_xref="GeneID:100130613"
                     /db_xref="HGNC:HGNC:34498"
     exon            1..135
                     /gene="PRR32"
                     /gene_synonym="CXorf64"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1012
                     /gene="PRR32"
                     /gene_synonym="CXorf64"
                     /codon_start=1
                     /product="proline-rich protein 32"
                     /protein_id="NP_001116188.1"
                     /db_xref="CCDS:CCDS48163.1"
                     /db_xref="GeneID:100130613"
                     /db_xref="HGNC:HGNC:34498"
                     /translation="MACIENVLGGHAPSPLVVSVDKNGNQELHHDMPLQCLSSKPEDD
                     AEPWGQPQVPLRPSVNVLTDLDSKQLEWPSERTGSCIPLHSLRAHRHPYGPPPAVAEE
                     SLATAEVNSSDALAGWRQEGQDAINVSWEVSGGPPALIVGGTKVNNGGTERGSNNARL
                     HVALPQGKGFFPPRGPQVRGPSHIPTLRSGIVMEVPPGNTRIACRGKLAHVSFPLRGP
                     CHPMHNWPRPIPLSSSTPGLPSCSTVHCFIPPRPPIFNPFLTMPLPFAPPPIFGPPLP
                     SYFAHFHSGGMPAPASPNREHS"
     exon            136..1263
                     /gene="PRR32"
                     /gene_synonym="CXorf64"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1241..1246
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRR32"
                     /gene_synonym="CXorf64"
                     /note="hexamer: AATAAA"
     polyA_site      1263
                     /gene="PRR32"
                     /gene_synonym="CXorf64"
                     /note="major polyA site"
ORIGIN      
        1 attctagttg ccaagcctct aaagcagaag caggagtcat ttctccagac ctagctggcc
       61 tgttcagtgg gttatctcca ccacctcagg aaagctattc tgatcaaatt tcttcatggc
      121 ttgtattgaa aacgtccttg gagggcacgc cccttcaccc ttggtagtat ctgtggacaa
      181 aaatgggaac caggagctgc accacgacat gcccctgcaa tgtctgagtt ccaagccaga
      241 ggatgacgca gagccctggg gtcaacctca agtaccgctg agaccttccg tcaatgtgct
      301 gactgatctg gatagcaagc aactggagtg gccctctgaa agaacaggat cctgcattcc
      361 tcttcatagc ttgagagctc atagacaccc ctacgggcca ccacctgctg ttgcagaaga
      421 gtccctagca acagcagaag taaacagctc tgatgcactg gcaggctgga ggcaggaggg
      481 acaggatgct attaatgtgt cctgggaagt ctctggcggc cctcctgcac tgatagtagg
      541 gggcacaaag gtcaacaatg ggggcactga gagaggcagt aataacgcaa ggttgcatgt
      601 agctttgcca caaggtaaag ggttctttcc acccaggggc ccacaagtga gaggcccttc
      661 acatattccc acccttagat cagggatagt aatggaggtg ccgcccggaa atacacgaat
      721 agcctgcaga ggaaagctgg ctcatgtttc tttcccactc aggggcccat gccaccccat
      781 gcataattgg ccaaggccta tcccgttgtc ttccagtact ccaggtttac cttcttgctc
      841 tactgttcat tgtttcatcc ctcctcgacc tccgattttc aatccctttc tcactatgcc
      901 tcttcctttt gctcctcctc cgatatttgg tcctccactg ccttcttatt ttgcccattt
      961 ccattctggg ggaatgccag ctcctgcatc acccaacaga gagcacagct gatggcaaaa
     1021 aggaaggatg aaaaaagggt tgtggaaaga ggtgaaagtt attcatttat gcttttatat
     1081 ttgaaacctt gtaccctccc acactctgtt tagcactaat gtgccctact tgaaaccacg
     1141 taccctccca cactctgttt agcactaatg tgccctattt gaaaccttgt accctaccac
     1201 actctgttta gcacaaatgt gccctacata ctggagatta aataaagatt gtgaagtctg
     1261 aaa
//
