LOCUS       NM_001007534            1740 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens PRR23 family member E (PRR23E), mRNA.
ACCESSION   NM_001007534 XM_209563
VERSION     NM_001007534.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1740)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1740)
  AUTHORS   Xie,T., Deng,L., Mei,P., Zhou,Y., Wang,B., Zhang,J., Lin,J.,
            Wei,Y., Zhang,X. and Xu,R.
  TITLE     Genome-wide association study combining pathway analysis for
            typical sporadic amyotrophic lateral sclerosis in Chinese Han
            populations
  JOURNAL   Neurobiol Aging 35 (7), 1778 (2014)
   PUBMED   24529757
REFERENCE   3  (bases 1 to 1740)
  AUTHORS   Chung,S., Low,S.K., Zembutsu,H., Takahashi,A., Kubo,M., Sasa,M. and
            Nakamura,Y.
  TITLE     A genome-wide association study of chemotherapy-induced alopecia in
            breast cancer patients
  JOURNAL   Breast Cancer Res 15 (5), R81 (2013)
   PUBMED   24025145
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC112482.4.
            
            On Jun 12, 2013 this sequence version replaced NM_001007534.1.
            
            Sequence Note: The RefSeq transcript was derived from the reference
            genome assembly. The genomic coordinates were determined from
            transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK097460.1, BC137154.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148874
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000624688.2/ ENSP00000493276.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-145               AC112482.4         48852-48996         c
            146-1740            AC112482.4         43942-45536         c
FEATURES             Location/Qualifiers
     source          1..1740
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q21.3"
     gene            1..1740
                     /gene="PRR23E"
                     /gene_synonym="C3orf56"
                     /note="PRR23 family member E"
                     /db_xref="GeneID:285311"
                     /db_xref="HGNC:HGNC:32481"
     exon            1..145
                     /gene="PRR23E"
                     /gene_synonym="C3orf56"
                     /inference="alignment:Splign:2.1.0"
     exon            146..1740
                     /gene="PRR23E"
                     /gene_synonym="C3orf56"
                     /inference="alignment:Splign:2.1.0"
     CDS             241..969
                     /gene="PRR23E"
                     /gene_synonym="C3orf56"
                     /codon_start=1
                     /product="proline-rich protein 23E"
                     /protein_id="NP_001007535.1"
                     /db_xref="GeneID:285311"
                     /db_xref="HGNC:HGNC:32481"
                     /translation="MGTGASEKQAEQKVRRAFEASEEAHGTLAASTPWVAMGSAYGSC
                     TCLGAQPVTDLALWPVIYSCMGFSPQAYPAFWAYPWVLYGGYLWMGYPPPAALVPSVW
                     LYWRGASSFDPLIGSPYLAALAPNLFPFPMKFPPTYSLASPTLGGATSSHCPQVGCWT
                     PASSAPRAAVEGPSRGAPYLKTCKAPPSEWASRFGIWAPLPCCSSELRPLPPSPIEDS
                     QLDPGCSRSSSRSPCRARRRLFEC"
     regulatory      1718..1723
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRR23E"
                     /gene_synonym="C3orf56"
                     /note="hexamer: AATAAA"
     polyA_site      1740
                     /gene="PRR23E"
                     /gene_synonym="C3orf56"
                     /note="major polyA site"
ORIGIN      
        1 agtggtctcc tgccgccacc tggaccgggg acagtaacgc ctagggagcc ccaagacctc
       61 ttgagagagc atttcagctc tgttgacaaa cctcaaccac ttgagggact tcgctggaaa
      121 gaaacgttct agaaagacca agtggatacc aggagccccg tgaggtgcgt gtggcctcag
      181 cttgcagagg agtgcacttg ccagacactt cggggctttg aagagcacag ctcatctaag
      241 atgggcacag gtgcatcaga gaaacaagca gagcagaagg tccgccgtgc cttcgaggcc
      301 tccgaggaag cccacgggac tctggcagcc tcaaccccct gggtggccat gggctctgcc
      361 tatggttcct gtacctgctt gggagcccag cctgtaactg acctggccct ctggcctgtc
      421 atctactcct gcatgggatt ttccccacaa gcttacccag ccttctgggc ttacccgtgg
      481 gtgctctatg gtgggtatct ctggatgggt tatccccctc cagctgcctt ggtgccttca
      541 gtgtggctgt attggagggg cgcctccagc tttgaccccc tcataggaag tccgtatctg
      601 gctgccttgg cccccaacct atttcctttc cccatgaaat tcccacccac ctactccttg
      661 gcttctccca ctctgggcgg ggccacctcc agccactgtc cccaggtggg atgctggact
      721 ccagccagct cagcccccag ggctgccgta gaggggccat ccagaggagc tccctacttg
      781 aagacatgca aagcccctcc ctcagaatgg gcctccaggt tcggtatttg ggcacctttg
      841 ccctgctgca gttcagagct ccgccctctg cccccttccc ccattgaaga ttctcagctg
      901 gacccgggct gctcccgctc ctcctcccgg tcaccctgca gggcccgccg ccgcctcttt
      961 gagtgctaat cagccctcta gacccagacc cacccaacaa tcagagacat gtctggtgga
     1021 gcccagccag ctgtggactt taagtttttg gaagagtctc agatgtaggt tgtttactat
     1081 tcttcagtac agagtacacc tcctggactc atgcaaggcc cctctatttg ctatttctct
     1141 ttactttgtt tttctgtttg cccttcaacc ctgatactgg caccttttct cctccccaga
     1201 ctgtcctggg cccgccctct agtagatttg ctgtgagtcc tcaaacatgc atgcatgcaa
     1261 ccttgtaaaa tgagcttatt taagctcaat ccaacctgta gaagcgctca gttagaatag
     1321 gcctccaggt ttggtatttg ggcacctgtg ccaccctcca gcccaggact ctctctgccc
     1381 ctcctcagca aagaccctca gcaggatccc cgcatccctg gccaccctgt ggggcctgct
     1441 gctgtctctt ccagcattgg tgtgtcctcc agggaaccac acactcaagc actttggaac
     1501 ccatggaatc cagtgagcac gtgctgtggg ctctgcctag aagcttccaa aacctgtttg
     1561 ttccagtgga cacagagtag gaaatgctga ctcgttcaga gcgctagtgc ccttgggtcc
     1621 ttgcgggtgt gctcttctca ctcctcaccc catcagcacc ttctggggta atgcacacac
     1681 cagtaaaatg tacagtgcat gcttttaaaa atttttaaat aaatgatact atgctataaa
//
