LOCUS       NM_199285               1523 bp    mRNA    linear   PRI 22-SEP-2024
DEFINITION  Homo sapiens proline rich 19 (PRR19), mRNA.
ACCESSION   NM_199285 XM_211429
VERSION     NM_199285.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1523)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1523)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BM762502.1 and AK124116.1.
            
            On Aug 14, 2020 this sequence version replaced NM_199285.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.671711.1,
                                           SRR14038195.1975983.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000341747.8/ ENSP00000342709.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-605               BM762502.1         1-605
            606-1523            AK124116.1         1039-1956
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..1523
                     /gene="PRR19"
                     /note="proline rich 19"
                     /db_xref="GeneID:284338"
                     /db_xref="HGNC:HGNC:33728"
     exon            1..372
                     /gene="PRR19"
                     /inference="alignment:Splign:2.1.0"
     exon            373..979
                     /gene="PRR19"
                     /inference="alignment:Splign:2.1.0"
     CDS             379..1449
                     /gene="PRR19"
                     /codon_start=1
                     /product="proline-rich protein 19"
                     /protein_id="NP_954979.2"
                     /db_xref="CCDS:CCDS33036.1"
                     /db_xref="GeneID:284338"
                     /db_xref="HGNC:HGNC:33728"
                     /translation="MDTQGPVSQPFQQPEKPGRVRRRKTRRERNKALVGSRRPLAHHD
                     PPVAIRDPPVVPTASKLVVITQGRLSREHRGLFNHEVKSLDVARLLSSGTLVPGSPTL
                     PAKPSPSPGRAQEPAPRSRDKENQVPGGSGPGPPSSPELSGVGQLLAELQCQLSLPQA
                     FPRRNLIQDARDAIVHTLQACHGCVPDLALVLRGCQPPLPGAKPGVSERKMTPFWINS
                     PDQVPEQERQRKQQGTKEFTFPMPYTSSMPTAHRGSLAPPRGPWPPYFPSLSSPSGTA
                     WGPPTAFDLLKSIWLVATPPPPRPWGVGLPQPLPQPSSPLLPRTSVLDWSPSPPSPLP
                     SLSWVVAQSSPEAWSFPPMRLY"
     exon            980..1523
                     /gene="PRR19"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1503..1508
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRR19"
                     /note="hexamer: AATAAA"
     polyA_site      1523
                     /gene="PRR19"
                     /note="major polyA site"
ORIGIN      
        1 agtttcccaa tcaggtagtg agagtggcac gaaccagccg ttctcctgag ccaccccccg
       61 cgcccccgga ctcctcaata tcccaggtgg gaacgctcac cagggacatc cagcgcccgt
      121 cgccctgtac gtcctgcacc ggcgtgggct tgctggctgg gttctcctct ccactcatct
      181 tggcgccgca gctcctgcag gatgagcgag tcgggtcggc ccgggagtgt tccgaacgga
      241 gctggctccg ccacgcccac tcctacccct cgcggcaaca aaggaccgtc ccaacgctag
      301 cacacccgcg gaggacgaag gccgatacag ggcgccgcct cctctccagg gacggaagcc
      361 ttcacttagg aggacaccat ggatacccag ggaccagtct cccagccttt tcagcagcct
      421 gagaaacctg gtcgtgtccg tcgtcggaag actaggcggg aacgtaacaa ggccctggtg
      481 ggcagccgcc ggccattagc ccaccacgat cctcctgtgg ccattcggga tccacctgtg
      541 gtccctactg cctccaagct cgtggtcata acccagggcc ggctgagccg ggagcaccgg
      601 ggtctcttca accacgaggt gaaatcccta gatgttgcaa ggctgcttag cagtgggacc
      661 ctggtgccag gcagccccac actccccgcc aagccctccc caagcccagg cagggcccag
      721 gaaccagccc cacggtccag ggacaaagag aaccaggtgc ctggaggttc gggcccaggc
      781 ccacccagtt ccccagagtt gtctggcgtg gggcagctgc tggcagagct gcagtgtcag
      841 ctgagtttgc cacaggcctt cccccggagg aacctgattc aggatgccag ggatgccatc
      901 gtgcacacct tgcaggcctg tcatggttgt gtgcctgacc ttgccctggt gcttcggggc
      961 tgccagccac ccttgccagg ggccaagcct ggggtctctg agagaaagat gacacccttc
     1021 tggattaata gccctgatca agtcccagag caggagaggc aaaggaagca acaagggaca
     1081 aaggagttca ccttccccat gccctacacc tccagcatgc ccactgcgca cagggggagt
     1141 ctggcaccgc caagaggtcc ctggccacca tactttccct cactgtcttc gccatctgga
     1201 acagcctggg gtcccccaac agcgtttgac ttgttaaaaa gcatctggct ggtagccacg
     1261 ccaccccctc ctcggccctg gggggttggc ctccctcagc ccctgcctca gccttcatca
     1321 cccctgttgc cccgaacctc tgtcctggac tggagcccca gccccccttc cccactgccc
     1381 agcctctcct gggtagtagc ccagagcagt ccggaagcct ggtcttttcc acccatgaga
     1441 ctgtactgag gagaggctga ggctagggct ggggacagat atcttgtact cccagtgacc
     1501 tcaataaagt acttttcatg gtc
//
