LOCUS       NM_173566              10827 bp    mRNA    linear   PRI 17-DEC-2024
DEFINITION  Homo sapiens proline rich 14 like (PRR14L), mRNA.
ACCESSION   NM_173566
VERSION     NM_173566.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10827)
  AUTHORS   Chase,A., Pellagatti,A., Singh,S., Score,J., Tapper,W.J., Lin,F.,
            Hoade,Y., Bryant,C., Trim,N., Yip,B.H., Zoi,K., Rasi,C.,
            Forsberg,L.A., Dumanski,J.P., Boultwood,J. and Cross,N.C.P.
  TITLE     PRR14L mutations are associated with chromosome 22 acquired
            uniparental disomy, age-related clonal hematopoiesis and myeloid
            neoplasia
  JOURNAL   Leukemia 33 (5), 1184-1194 (2019)
   PUBMED   30573780
  REMARK    GeneRIF: we report for the first time the finding of loss of
            function PRR14L mutations in myeloid neoplasia and ARCH. Knockdown
            of PRR14L results in altered myeloid differentiation and cell
            growth in vitro and our data suggest that PRR14L may play a role in
            cell division.
REFERENCE   2  (bases 1 to 10827)
  AUTHORS   Fransen,E., Bonneux,S., Corneveaux,J.J., Schrauwen,I., Di
            Berardino,F., White,C.H., Ohmen,J.D., Van de Heyning,P.,
            Ambrosetti,U., Huentelman,M.J., Van Camp,G. and Friedman,R.A.
  TITLE     Genome-wide association analysis demonstrates the highly polygenic
            character of age-related hearing impairment
  JOURNAL   Eur J Hum Genet 23 (1), 110-115 (2015)
   PUBMED   24939585
REFERENCE   3  (bases 1 to 10827)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA861907.1, CD697995.1, CT841517.1, BX647272.1 and AK090566.1.
            
            On Nov 23, 2018 this sequence version replaced NM_173566.2.
            
            ##Evidence-Data-START##
            CDS exon combination :: CT841517.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMN03568911 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000327423.11/ ENSP00000331845.6
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-99                DA861907.1         3-101
            100-166             CD697995.1         122-188
            167-6809            CT841517.1         1-6643
            6810-7694           BX647272.1         1114-1998
            7695-7915           AK090566.1         44-264
            7916-10827          BX647272.1         2220-5131
FEATURES             Location/Qualifiers
     source          1..10827
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q12.2"
     gene            1..10827
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /note="proline rich 14 like"
                     /db_xref="GeneID:253143"
                     /db_xref="HGNC:HGNC:28738"
                     /db_xref="MIM:621035"
     exon            1..140
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            141..665
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..6647
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /note="proline rich 14-like protein"
                     /codon_start=1
                     /product="protein PRR14L"
                     /protein_id="NP_775837.2"
                     /db_xref="CCDS:CCDS13900.2"
                     /db_xref="GeneID:253143"
                     /db_xref="HGNC:HGNC:28738"
                     /db_xref="MIM:621035"
                     /translation="MLSSGVETQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSV
                     IPDVKPGASSSLLSQNRALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTAGGS
                     VASGILDRAKRSESMEPKVFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQED
                     LLMQSSKELSHVDLPEDFLRSKEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNG
                     NVSKDLSAGCGEFQEVDKIMTSDEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELK
                     SCPWLSLPGNSAISNVDNGKEELCKPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATS
                     PLKENSEVSCFTSDLSGPESRTISLENCGFEGGGLLKRSAEKTDSSYFYRGDDQGKNL
                     ASREENEERLLIPRSERGGPFLFNAREPEKEISGRCSGEKEPVVSPKENIHNNCIQDS
                     LHTGNSSSLMPNSFTEATEVMLNKNDLKITVHVQGNLTNPEDHKETFTNMSHPGGHSE
                     ESSFSSLMQIEEAGQTTPVEPNILSKSFYTKDCNSLVSIQRNLEGNTQLNEASCNDFL
                     FERKSIVSLMPEDQISPVSEVLKPKQGTALLLPSPEFDYRPESEKVIQTSHDDIPLLD
                     EQSIACEMNELSCTNELVVNKVESECVLNQQVSLNSQEHANLPTDSLLHLNKEMPLAT
                     GRDAHQSHHPPLEGRADVIADIQTIPIQTKIKDISPPGNQTCGASSNCPTLNIKPVSL
                     ERKKEMADSGTKALHSRLRSNKREAAGFPQVVSVIECHSVQSQDISSCHRVRKNVSQE
                     NMCSASAAFKSSKISLQVDNSLITKYENAFQHRDHCCQGTGHSVEKSSCKVSYTSQER
                     ELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSSSIKLSEEGLEGKEQDVSKET
                     VFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSSFKNVKSVETLDQKADEVLDC
                     QSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNHNQKDLLVSSGSNNSLPCGSP
                     KKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLDVKASNLLDCGARQEKLAF
                     QEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKKSCEENVCRSLKDCEME
                     KCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGSRLEP
                     NSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLC
                     KPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKACHPHENSSD
                     RHLPLTVKTDIKVKGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFK
                     CRGILNHAEKQQSPEVLDYMLQKEEKYIRQQKAHTISQQCISSSLLLDDAQNQNQPKA
                     DKDESTMINEITLAKLAKDSIVAQTQKLEDQKEERLHHPLRKDTESCTSPCLLGAPRK
                     AQDPSSAGCDQIHGAFAKKGVLPLKKQPHRTCKKVSYQEQIIVGRKIGKIRSSAFLKS
                     SSNPIPTKAHRLLSLCTLSAPTRLEPETAPTKSLVSHIPKQMSTPCHPLRSLNFRKTT
                     KESALLNKLSILASKLAPAMKTQKLRYRRCSSELLPMAKSYKRLRYKRLLDGFSSSTE
                     QLNPYLAASGWDKRPNSKPMALYSLESIKMTFIDLSNKMPSLLFGSEIFPVSFHVKSS
                     SSDCTTESSRTFPEHCAPARLALGEALQCPSQPPKWTFSFFLSHGCPGMATFREDTGV
                     HSQTHTQAPPQPPAPLQDYGGTAIVQTRADCSVLGLHTLLALCSPGCYRIWTKKRSFS
                     SHMPTMQRLFMTQFTQGLKGLRSPASIADKVFCSLPYSVGRVLSIWSQHGPSVCSFEI
                     SSLHSPHCKRQPSLGTTSSHTMLPYVPLPGMEATYNTSGSQTRLEPPFPALVPKSCLV
                     AESAVSKLLLSASEFQVRGLDELDGVKAACPCPQSSPPEQKEAEPEKRPKKVSQIRIR
                     KTIPRPDPNLTPMGLPRPKRLKKKEFSLEEIYTNKNYKSPPANRCLETIFEEPKERNG
                     TLISISQQKRKRVLEFQDFTVPRKRRARGKVKVAGSFTRAQKAAVQSRELDALLIQKL
                     MELETFFAKEEEQEQSSGC"
     exon            666..738
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            739..5947
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            5948..6019
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            6020..6191
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            6192..6298
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            6299..6370
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     exon            6371..10827
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10801..10806
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /note="hexamer: AATAAA"
     polyA_site      10827
                     /gene="PRR14L"
                     /gene_synonym="C22orf30"
                     /note="major polyA site"
ORIGIN      
        1 agagacgaag aggtggcggc ggccggagcg cccccggcct ctgtcggctc cgtaggctca
       61 ggtagacctg gcgacgacgg ggctgcagct gcaggggctg agctggctgg gcaagcgcgg
      121 gccgcggagg aggtctcagg ggtgaatcat ttgatgtaaa agacttgact ccataatctg
      181 catctgtcct aatgctgtca tctggagtag agactcagcc agttccactt gattcctcca
      241 tgtctgccgt ggtacaggaa ttatactctg aactcccagt aagtgtctcc agagagcttc
      301 atgctgaccc tgagccaagt gtgattccag atgtaaaacc tggagcctca agctctcttt
      361 taagtcagaa tagggcattg cccttggagc tgcagaggac tcatgtggag agttgttgtg
      421 aagaaaccta tgagaccttg gatcatggga gtgagcctgg gcgatgtggg ctagtggact
      481 ccacagcagg aggttctgtg gcatctggga tcttggatag ggcaaagaga agcgagagca
      541 tggagccaaa ggtcttcaga gatccagggg gccaggcagg aattataaga gaaccctctg
      601 agggagcaaa ggaagatcca catcaacatt ccacagctgc tgaagaaaag actagcccga
      661 gtcaggagga tctcctgatg cagtccagca aagaactttc acatgtggac ctccctgaag
      721 attttctaag gagcaaagaa ggaaatgtac agattacagc tgaaactctg ctaaaatccg
      781 ccgaagtaca aggtatgaag gtcaatggga ctaagacgga taataatgaa ggacacaaaa
      841 atggcaatgt gagtaaagat ctctcagctg gatgcggtga attccaagaa gtagacaaaa
      901 tcatgaccag tgatgaggtt tcagaaacca gcacattagt taccccagaa cctttaacct
      961 ttgtggaccc tgtattaaca gaagcaactc ctaaagaaaa agaatgtgaa gaattaaaaa
     1021 gttgtccttg gttgtcatta ccaggaaaca gtgccatttc taatgtggac aatgggaagg
     1081 aagagttgtg taaaccaaac ctggtctgtg aagcagatga caatcaccaa cagcttcatg
     1141 gccaccataa tgaacaaccc agttctacac atgatagtcc cacagccaca agccctttga
     1201 aagaaaattc tgaagtttca tgtttcacat cagacttgtc tggtccagaa tccagaacaa
     1261 tatccttaga aaactgtggt tttgaaggtg gtggtttgct aaagagatct gctgaaaaga
     1321 cagacagttc ttatttttat aggggggatg atcaagggaa gaacttggct tctagagaag
     1381 aaaatgagga acggcttttg attcctagga gtgaaagagg tggacctttt ctttttaatg
     1441 ccagggaacc agaaaaggag attagtggtc gttgttctgg tgaaaaagag cctgttgttt
     1501 ctccaaagga aaatatccac aataactgca ttcaagacag tctccataca gggaactcta
     1561 gttctttaat gcccaattct tttactgaag ccacagaagt aatgttaaat aaaaatgatt
     1621 tgaaaattac tgtacacgtt caaggtaact tgacaaaccc tgaggaccat aaagaaactt
     1681 ttactaatat gagccatcct ggtggacact ctgaagaaag cagtttttcc tccttgatgc
     1741 agattgaaga ggcaggacag acaacccctg tagagcccaa tatattaagt aaatcttttt
     1801 acactaaaga ctgtaactcc ttagtcagca tccagagaaa tctggaaggc aacacccagt
     1861 taaatgaagc atcatgtaat gattttctgt ttgaaagaaa atccattgtg agtttaatgc
     1921 cagaggatca aataagtcct gtaagtgagg tattaaaacc caagcaaggt actgctctgt
     1981 tgctaccatc cccagaattt gattacagac ctgagtcaga aaaagttata cagacctcac
     2041 atgatgatat tccactttta gatgaacaga gcatagcctg tgagatgaat gaactttctt
     2101 gtaccaatga actggttgta aacaaagtag aaagtgaatg tgttttaaat caacaagtgt
     2161 cccttaattc tcaagaacat gcaaatttgc caactgactc tctactgcat ttaaacaaag
     2221 agatgccttt agcaacaggc agagatgccc atcagagcca tcaccctcca ttagagggta
     2281 gagcagatgt cattgctgat atacaaacca ttcccattca gacaaaaata aaagacatct
     2341 ctccaccagg taaccaaacc tgtggtgcct cttcaaactg tcccacctta aacatcaaac
     2401 cagtaagcct agagagaaaa aaggaaatgg ctgattcagg aacaaaagct ctacattcca
     2461 ggctgcgctc aaataagaga gaagcagctg gctttcctca agtggtctct gtcatagaat
     2521 gtcacagcgt tcaatctcag gatatctcta gctgtcatcg tgtaagaaaa aatgtatccc
     2581 aggaaaacat gtgttctgct tctgctgctt tcaagtccag caaaatcagc ctgcaagttg
     2641 ataactcttt gataacaaaa tatgaaaatg catttcagca ccgtgatcac tgctgccaag
     2701 gaacaggaca ctctgtggaa aaaagcagct gtaaagtgag ttacacatca caggaaaggg
     2761 aacttgatgg gaaagaaacg aatggcagcc ttccaggaga taagatcaga aacaaaatgg
     2821 tagcaggctt gttaaatagt ggaatttcaa acaaaaccat tcacacctcc agtagcatca
     2881 aactcagtga ggaagggctg gaaggaaagg agcaggatgt atccaaagaa actgtatttt
     2941 gtaagtataa catctctgat catgctatac aagaactaaa ccagactgta aacattccag
     3001 gtcctgaaaa agtgttggac cagtctccta ctgttatgtt ctccagtttt aaaaatgtaa
     3061 aatcagttga aacactcgat cagaaggcag atgaagtcct tgactgtcag agtaaccaaa
     3121 acagaccaga tgaatgcaaa agtgaaggtc agtcagccaa ggagatgcta agtagtgacc
     3181 agagagagac tgtcaccgag cctcacgggg aggtaaacca caaccaaaag gatctgctgg
     3241 tcagctcagg cagtaataac tcactacctt gtggtagtcc aaagaaatgc aatttgaaag
     3301 gagcctttgt caagatgtct ggttgtgatg agtccacaga aggtatggta gacatcgtct
     3361 acacggactg tagtaataag cttgcagaag gtgtgctgga cgtgaaggca tctaatctac
     3421 tggattgtgg tgcaaggcaa gagaaactgg catttcaaga ggactccagg agtaccttgt
     3481 ctcggagaga actggatgct gcacatacag gaacaactgg tcaggattca gatttcccag
     3541 ttactgctgc ttctacagtg gactttctca aaataaaaaa atcatgtgaa gaaaacgtat
     3601 gcagatcttt aaaagactgt gaaatggaaa agtgtccaga ctcttgtgcc catgagatgg
     3661 agtctgttgc agatcatgaa ccaaataaaa gaatattggg cagagtaaat ttgtctttaa
     3721 atgatagcca ttatggacag caagataaag gaacatctct cagagaaaca caagaaatga
     3781 ctgaaggatc aagactagaa ccaaactctg agtttggcaa agaaagtacc tttggaattt
     3841 cctcaaaaga gtcgatgtct tgccatgatg aaagctctgt ttccctaaga agcctgaaat
     3901 ccattgaaat aatgccttct caagaaaatt cagaaactaa tgttaacagt gaagaaactg
     3961 acctgaaaaa tctttgtaaa ccaaaagatg gtgaaatgct ttgtgaaaat gtaaaggact
     4021 gcacagtcct tcctgagatg aaggaaatag tatcaagaga ttggagtaat tctagtgaca
     4081 gagacagcgt atgtacctgt gtggaaaaga atgcttgcaa agcttgtcac cctcacgaga
     4141 attcctctga cagacatttg cctttgacag tgaaaacaga tattaaagtg aaaggagaag
     4201 aaaccgaaga gcatcagagg ggacgactgg gttacttaac tgttggggag caatctgagg
     4261 agttggttac cagagaaact ggcgatggcg atcccgtgag caacatctct cagacccatt
     4321 ttaaatgccg ggggatactt aatcatgctg aaaaacagca gagccctgag gttttggact
     4381 acatgttgca gaaagaagag aaatatatac gtcaacaaaa agcacatacg atatcgcaac
     4441 agtgcatatc atctagtctg ttgttagatg atgcacaaaa tcagaaccaa ccgaaggctg
     4501 acaaagatga gtccaccatg atcaatgaaa tcaccctagc aaagctggcc aaggacagca
     4561 ttgtggcaca gactcagaag ttagaagacc agaaggagga aaggttacat catccattaa
     4621 ggaaggacac tgagtcatgc acaagtcctt gccttcttgg tgcccctcgg aaagcacaag
     4681 acccctcctc tgctgggtgt gatcaaatac atggtgcctt tgcgaagaaa ggagttcttc
     4741 ccttaaagaa gcagccccat cgaacttgta agaaagtttc ctatcaggag caaatcattg
     4801 ttgggagaaa aataggtaaa atcagaagtt ctgccttttt aaagagttct tccaatccca
     4861 tccccacaaa agcgcacaga cttctcagtt tgtgtactct gtctgcacct acacgattag
     4921 aacctgaaac agcacctacc aagagcttgg ttagtcacat accaaagcag atgtctacac
     4981 cgtgccatcc cttgaggagc ctgaatttta ggaagactac caaagaatca gccttactaa
     5041 acaagctgtc catccttgcc tccaaactgg ccccagccat gaagactcag aagctaagat
     5101 accgacggtg ttcctctgaa cttcttccaa tggctaaaag ctacaagcgc ctcagatata
     5161 aaagactcct ggacggattt tcatccagca cagagcagct gaatccatat ttggcagcta
     5221 gtggatggga taagaggcct aacagtaagc ccatggcact ttattctctc gaatccatca
     5281 agatgacctt catagatttg agcaacaaga tgccgtccct gctgtttggt tctgaaatct
     5341 tcccagtatc ctttcatgtg aaatcatcca gctcagattg cacgactgag tcctcaagga
     5401 cttttcctga gcactgtgct ccggcaaggc ttgccttagg agaggccctc cagtgcccgt
     5461 ctcaacctcc caagtggacc ttttctttct tcttgtccca cggttgccct gggatggcaa
     5521 cattcaggga agacactggc gtccatagtc agacccacac tcaggctcct ccccagcctc
     5581 cagctcctct ccaagactat ggaggcactg ccatagtcca gaccagagca gactgctctg
     5641 tccttggcct tcacacactt ctagcacttt gttccccagg atgttaccga atctggacaa
     5701 aaaaacggag cttctccagc cacatgccta ccatgcagag gctcttcatg acccagttta
     5761 cacagggcct gaaagggtta cggtctccag cctccatagc agacaaggtc ttctgttctc
     5821 tgccctactc ggtgggcaga gtcctatcca tttggagcca gcatggtcct tctgtctgct
     5881 ccttcgaaat ctcttctctt cattcccctc actgcaagcg gcaaccaagt ctgggcacca
     5941 caagcagcca caccatgtta ccatatgtgc ctcttccagg catggaagct acatataaca
     6001 ccagcggcag tcagacgagg ctggagcctc cattccctgc cttggtacca aagtcttgct
     6061 tggtagcaga atcagctgtc agcaagctcc tgctttcagc ctctgagttc caggttcgtg
     6121 gattggatga gctggatggt gtgaaagcag catgcccctg cccacagagc agccccccag
     6181 aacagaaaga ggctgagcca gagaagaggc caaagaaagt ctcacagatt cgcatccgga
     6241 aaaccattcc taggccagat cctaatctta cccccatggg ccttcctcga cccaaaaggt
     6301 taaagaagaa ggagtttagt ttagaagaga tatataccaa caagaattat aaatctcctc
     6361 ctgcaaacag gtgtttagag accatctttg aggaacccaa ggaacgaaat ggtacactaa
     6421 tctcaatcag ccaacagaag aggaagcgag ttctagaatt tcaggatttt acagtcccgc
     6481 gaaagaggag agctcgaggc aaagtcaagg tggcaggcag ctttaccagg gcccagaagg
     6541 cagctgtgca gagtcgagag ctggatgctc ttttgataca gaaactaatg gaactggaga
     6601 ccttctttgc caaggaagag gagcaggaac aatcatcagg ctgttgagaa gcgattcagt
     6661 ttgagggtct caattttagg gtttttttgt tttgttttgt ttttgggttt tttttttttt
     6721 tttggacctc cttggaaaag gttgcctaat tttgccctac cgccaaacca ctcaaaaatg
     6781 cacagtccat gaatttttac ctatttcaag gtgcaacctt tttagaaact ggtgaaggag
     6841 ggtcctctac ttttactgct gagtatagaa cctcaggaat gctccctttc tcctggaaat
     6901 ggacctgaac gacatccagc cacctcctca gtctctgcca tccacaggag gaagcagcag
     6961 cctatcttca gtaacactag gattccaagg acacacagga tttgcacgtc catatgaaag
     7021 ttccgctttg tttacggtgg tgctagacca agattattag aaacgtggcc tagggagggg
     7081 gacctggcgt cctgtcctgt gtggtctcac tggctcattt cagtagttga ggaaagatga
     7141 gctgttgtgt tttcttatct tttgtctgcc caggacctat tgatgtgagt gtatgtgaga
     7201 gtgtttgtgt gtgtgtggct ttttcccatc gttttctccc ctctgtgact gggtcactag
     7261 tgccagagga gcccgtccag gccccattcg aagtaagttg cactttttaa tgttgtggtg
     7321 tggattattt tcatttgttt tattttcttt tttgttgttg tttttgtact attattgctg
     7381 catgtgtgga gcctttaaat gtgattttaa aacatttttt taaggagaaa aacaatacat
     7441 gtcttaagaa tacatgatag gcatttgacc cagttgatcg ctgcatggaa gagacatttt
     7501 tcctattcat gtgtttcagg caatcccttc cccatctcca gcttctagtg taactcatta
     7561 gagggagcac tttttttcat ctgggttctc attcttgccc accaaataca tgtatttatt
     7621 ttagtgattt aagtaagagc aggtttctct cccgatcatt gaaaaactac tatggttggg
     7681 tgtggtctta atggttttta tctgaaatgg tgttaggtaa caaaattgag tacaacggct
     7741 tgggcagtga tacaggctga cccacagtat ttgtggcttt ccaggcagcc cgcttcaagt
     7801 gtggggagag agtcggggtc atgtttcaga cccagagatg tgttcctgca gtgggatctc
     7861 aaaaatcccc agccagcctt ctttgagggc cacctcattg tactctgggc tcctacgtca
     7921 catctaccgg aactgtcaaa tgctggagtt agccgagttt ctgggtttgt gcctgcagga
     7981 gtctgtgggc agagggatgc tgtgggtcag cagcctcgag gtcttgttcc ttttccactg
     8041 aagtcctgtg tgtccatatc ctgctcccct tcccctcctt ctctaggggt ttctctttct
     8101 ctctcaaaac aagagtttag agaattaaca ttccatggct agtgagtggg atgcaaaagt
     8161 catcgtcagg acaccagcat cacctcttca tatcctcctg ggagccactg gcatggagca
     8221 gccgccgatg ggaaccgtca gagttctagg gacatttcca agtcagtcta ttagagaaga
     8281 gtgagtggca cgtcctggaa tgttggccaa ctctcctagg tttcttttgc ttccccattt
     8341 gctagtggat ggggagatgg gttgggggtg gggggtctct atgtgccttg cttttgcagg
     8401 ttgacagtct atgccacact ggagcagaaa aactgacatg agccagaggg aaaagtgtgc
     8461 cacggctatg ttctaggccc actgcctcag acatagcatt gagacgagtg aaatacacac
     8521 ttggtcatcc acggaggctt ccaaggccat ggccaaatac agttagaaga gagccaggct
     8581 tccgtaccag ctctgaatga tgctaaccag attctgtcat tctacatcca ctttgcccag
     8641 actgtataga cacgacctat gtttcacctc aatacctctc ccttcctggg acagggttct
     8701 tagacactaa atgcttctct ctgacttttt tgcttaaggg agtgggatga gtagtacatt
     8761 ttgcccttgt ccaggcatgt ttaaggagct cctactggac aggttgcaga ctagcagtga
     8821 gtcaacagag ccctgtttgc cagctctgtt gccagtatag atgcagtgat gtggcggcta
     8881 tgtttcccag agacaacagt gggcacagct atagtgtcac caacatggca gagatagttt
     8941 caactgtgcc tgttacaggt gtggcactcg aaggaccaga agcagcggtt tggaacatgg
     9001 gtaactggga gcagaggact ggaagaaaca gagctgggct ccttccctgt cctgacaatg
     9061 taggagagga gttgttgtga ggccagccct gcccgtcgtt gaaattctgg acctaccctc
     9121 tagctaggtc ccttcccctg ctccaaagtt gagaaggggg ccccactgca aacttgaaat
     9181 tacttacctg aaggtgatgt atatacctag gctccagctg cgctcagcca cacctgtctt
     9241 aacattcagt ttcggcactg agccagctgc agtgttgtca ggggtcccca ggcccgtggt
     9301 ccctaaccac gatgggacat ggtaatcggc tgctggcaca ccacctgccc agagctacag
     9361 gaggtctggt tctggggtgg agttggtaca gtttctgagt atgggaactt ccctccccaa
     9421 gtggtgggaa gttacagtta actacagctt actcaactat cacttccaga ggtttagtgt
     9481 ttttaatatg ggaaagagga gaaatctcag gtctaatcag ggttctgccc atcagctttt
     9541 cactgaaact ttcaactgtg ttttgttttt tgtttttttt tccatctttc agtttctagc
     9601 tgtgtttgcc ttctccctcc gcgttccctc ctcttttttt gcttttggtc tcctttccag
     9661 cttcatgtct ccatgagttc agctgtacct catctcctgt taaagcagat catgtccact
     9721 ttttcttact gaccttactc taagctacag tagctgaggg aggtacggtg aagacatgta
     9781 gcgtttgcct tattcggagc ctgaggagcc cagaaaccca tgctgtgaat cccaaaactc
     9841 agcgctcctc aagagctgtg aaaatcatga tactttgtca caattttgcc tgaaagggtc
     9901 tttggcacgg gctccagagc caacctgagg tccattccag atcccactat ctgggcgtga
     9961 gacctccccc gtggctcctt ccttgcccac tgagccaaga gcagcaggga gcgtacagga
    10021 cgggagcagc agatccaagg ccgcggtgca gccaatgaat gcacggccgt cgctccgtct
    10081 ccaggctgga attccgtctc ataatcaatg ccatgtacat taagatctgc gaaagaccaa
    10141 cttttaggca gtgatacttt tctcccattc cctggggtgg ggggagtatg cagttggtgc
    10201 tttctgtaat tcccttgttc tgttttgttt ctgtaagctt ttcccctggt gtcatggaaa
    10261 ggacttctta aataaccaca ttgtgggtgg ctgtatccaa agtttaaata attggccaga
    10321 agtgcagagt atcctttcct ggattcgtgt cagaaaaggg ctccttgcca caactgaact
    10381 tactgtataa aaacctggct agggagattt aattttacta aaattacagt ttaatgttac
    10441 cgtctagcca caaatcaagc agcaaaagct attttgatga tgaaaggggg tccccgttga
    10501 gctggccatc tagtgcagtg tgctctcaga ttccatgttt gttgattgtg tgtcttcaca
    10561 agcccctctc tggtgctgaa ttggatttga attcttggtg agaggcctca gcatctcctt
    10621 gggctggtct gggccagtaa aaatagctgc ctgacatgtt tatatattat catggtcagt
    10681 agttcaatga aatttgtaca tttttggtaa cattggtata catgatgccc ctgcagttcc
    10741 ttttctgttt ggtagtttgt gactctaaga tttccactgt tatgtgtgtt aatttatgaa
    10801 aataaatttt tttgaaaacc tttcaaa
//
