LOCUS       XM_047416378            3944 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens prominin 1 (PROM1), transcript variant X16,
            mRNA.
ACCESSION   XM_047416378
VERSION     XM_047416378.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3944
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..3944
                     /gene="PROM1"
                     /gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
                     PROML1; RP41; STGD4"
                     /note="prominin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 5 mRNAs, 80 ESTs, 93 long
                     SRA reads, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 22 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:8842"
                     /db_xref="HGNC:HGNC:9454"
                     /db_xref="MIM:604365"
     CDS             278..2779
                     /gene="PROM1"
                     /gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
                     PROML1; RP41; STGD4"
                     /codon_start=1
                     /product="prominin-1 isoform X6"
                     /protein_id="XP_047272334.1"
                     /db_xref="GeneID:8842"
                     /db_xref="HGNC:HGNC:9454"
                     /db_xref="MIM:604365"
                     /translation="MALVLGSLLLLGLCGNSFSGGQPSSTDAPKAWNYELPATNYETQ
                     DSHKAGPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKIVYYEAGIIL
                     CCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAISLLVICIII
                     SIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQYNTTKDKAF
                     TDLNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNSTLKSLHQQST
                     QLSSSLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQLPPVDAELD
                     NVNNVLRTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSDIDNVTQRLP
                     IQDILSAFSVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVIFYYLGLLCG
                     VCGYDRHATPTTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFGANVEKLICE
                     PYTSKELFRVLDTPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKNRGTYGTLHL
                     QNSFNISEHLNINEHTGSISSELESLKVNLNIFLLGAAGRKNLQDFAACGIDRMNYDS
                     YLAQTGKSPAGVNLLSFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQQRVLPIEQS
                     LSTLYQSVKILQRTGNGLLERVTRILASLDFAQNFITNNTSSVIIEETKKYGRTIIGY
                     FEHYLQWIEFSISEKVASCKPVATALDTAVDVFLCSYIIDPLNLFWFGIGKATVFLLP
                     ALIFAVKLAKYYRRMDSEDVYDDVETIPMKNPSQH"
ORIGIN      
        1 gagctaaggg aagggcggcg gcagcggtga ctagggcggg agcaggagcg ggagccgggt
       61 gcacgggatg gtgccttgag tgaatgaccc ccttggagaa cattcttccg catccctcgc
      121 ctcaagccag cctcagacag aaaactgaag attcagcaga tccagtgctt cctgctcctc
      181 ttctgcccag gaacacgctt gccttcccca aggcttccag aagctctgag gcaggaggca
      241 ccaagttcta cctcatgttt ggaggatctt gctagctatg gccctcgtac tcggctccct
      301 gttgctgctg gggctgtgcg ggaactcctt ttcaggaggg cagccttcat ccacagatgc
      361 tcctaaggct tggaattatg aattgcctgc aacaaattat gagacccaag actcccataa
      421 agctggaccc attggcattc tctttgaact agtgcatatc tttctctatg tggtacagcc
      481 gcgtgatttc ccagaagata ctttgagaaa attcttacag aaggcatatg aatccaaaat
      541 tgattatgac aagattgtct actatgaagc agggattatt ctatgctgtg tcctggggct
      601 gctgtttatt attctgatgc ctctggtggg gtatttcttt tgtatgtgtc gttgctgtaa
      661 caaatgtggt ggagaaatgc accagcgaca gaaggaaaat gggcccttcc tgaggaaatg
      721 ctttgcaatc tccctgttgg tgatttgtat aataataagc attggcatct tctatggttt
      781 tgtggcaaat caccaggtaa gaacccggat caaaaggagt cggaaactgg cagatagcaa
      841 tttcaaggac ttgcgaactc tcttgaatga aactccagag caaatcaaat atatattggc
      901 ccagtacaac actaccaagg acaaggcgtt cacagatctg aacagtatca attcagtgct
      961 aggaggcgga attcttgacc gactgagacc caacatcatc cctgttcttg atgagattaa
     1021 gtccatggca acagcgatca aggagaccaa agaggcgttg gagaacatga acagcacctt
     1081 gaagagcttg caccaacaaa gtacacagct tagcagcagt ctgaccagcg tgaaaactag
     1141 cctgcggtca tctctcaatg accctctgtg cttggtgcat ccatcaagtg aaacctgcaa
     1201 cagcatcaga ttgtctctaa gccagctgaa tagcaaccct gaactgaggc agcttccacc
     1261 cgtggatgca gaacttgaca acgttaataa cgttcttagg acagatttgg atggcctggt
     1321 ccaacagggc tatcaatccc ttaatgatat acctgacaga gtacaacgcc aaaccacgac
     1381 tgtcgtagca ggtatcaaaa gggtcttgaa ttccattggt tcagatatcg acaatgtaac
     1441 tcagcgtctt cctattcagg atatactctc agcattctct gtttatgtta ataacactga
     1501 aagttacatc cacagaaatt tacctacatt ggaagagtat gattcatact ggtggctggg
     1561 tggcctggtc atctgctctc tgctgaccct catcgtgatt ttttactacc tgggcttact
     1621 gtgtggcgtg tgcggctatg acaggcatgc caccccgacc acccgaggct gtgtctccaa
     1681 caccggaggc gtcttcctca tggttggagt tggattaagt ttcctctttt gctggatatt
     1741 gatgatcatt gtggttctta cctttgtctt tggtgcaaat gtggaaaaac tgatctgtga
     1801 accttacacg agcaaggaat tattccgggt tttggataca ccctacttac taaatgaaga
     1861 ctgggaatac tatctctctg ggaagctatt taataaatca aaaatgaagc tcacttttga
     1921 acaagtttac agtgactgca aaaaaaatag aggcacttac ggcactcttc acctgcagaa
     1981 cagcttcaat atcagtgaac atctcaacat taatgagcat actggaagca taagcagtga
     2041 attggaaagt ctgaaggtaa atcttaatat ctttctgttg ggtgcagcag gaagaaaaaa
     2101 ccttcaggat tttgctgctt gtggaataga cagaatgaat tatgacagct acttggctca
     2161 gactggtaaa tcccccgcag gagtgaatct tttatcattt gcatatgatc tagaagcaaa
     2221 agcaaacagt ttgcccccag gaaatttgag gaactccctg aaaagagatg cacaaactat
     2281 taaaacaatt caccagcaac gagtccttcc tatagaacaa tcactgagca ctctatacca
     2341 aagcgtcaag atacttcaac gcacagggaa tggattgttg gagagagtaa ctaggattct
     2401 agcttctctg gattttgctc agaacttcat cacaaacaat acttcctctg ttattattga
     2461 ggaaactaag aagtatggga gaacaataat aggatatttt gaacattatc tgcagtggat
     2521 cgagttctct atcagtgaga aagtggcatc gtgcaaacct gtggccaccg ctctagatac
     2581 tgctgttgat gtctttctgt gtagctacat tatcgacccc ttgaatttgt tttggtttgg
     2641 cataggaaaa gctactgtat ttttacttcc ggctctaatt tttgcggtaa aactggctaa
     2701 gtactatcgt cgaatggatt cggaggacgt gtacgatgat gttgaaacta tacccatgaa
     2761 aaacccatca caacattgat agctgatgtt gaaactgctt gagcatcagg atactcaaag
     2821 tggaaaggat cacagatttt tggtagtttc tgggtctaca aggactttcc aaatccagga
     2881 gcaacgccag tggcaacgta gtgactcagg cgggcaccaa ggcaacggca ccattggtct
     2941 ctgggtagtg ctttaagaat gaacacaatc acgttatagt ccatggtcca tcactattca
     3001 aggatgactc cctcccttcc tgtctatttt tgttttttac ttttttacac tgagtttcta
     3061 tttagacact acaacatatg gggtgtttgt tcccattgga tgcatttcta tcaaaactct
     3121 atcaaatgtg atggctagat tctaacatat tgccatgtgt ggagtgtgct gaacacacac
     3181 cagtttacag gaaagatgca ttttgtgtac agtaaacggt gtatatacct tttgttacca
     3241 cagagttttt taaacaaatg agtattatag gactttcttc taaatgagct aaataagtca
     3301 ccattgactt cttggtgctg ttgaaaataa tccattttca ctaaaagtgt gtgaaaccta
     3361 cagcatattc ttcacgcaga gattttcatc tattatactt tatcaaagat tggccatgtt
     3421 ccacttggaa atggcatgca aaagcaatca tagagaaacc tgcgtaactc catctgacaa
     3481 attcaaaaga gagagagaga tcttgagaga gaaatgctgt tcgttcaaaa gtggagttgt
     3541 tttaacagat gccaattacg gtgtacagtt taacagagtt ttctgttgca ttacgataaa
     3601 cattaattgg agtgcagcta acatgagtat catcagacta gtatcaagtg ttctaaaatg
     3661 aaatatgaga agatcctgtc acaattctta gatctggtgt ccagcatgga tgaaaccttt
     3721 gagtttggtc cctaaatttg catgaaagca caaggtaaat attcatttgc ttcaggagtt
     3781 tcatgttgga tctgtcatta tcaaaagtga tcagcaatga agaactggtc ggacaaaatt
     3841 taacgttgat gtaatgaaat tccagatgta ggcattcccc ccaggtcttt tcatgtgcag
     3901 attgcagttc tgattcattt gaataaaaag gaacttggaa aaca
//
