LOCUS       XM_011513895            4161 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens prominin 1 (PROM1), transcript variant X4,
            mRNA.
ACCESSION   XM_011513895
VERSION     XM_011513895.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011513895.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4161
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..4161
                     /gene="PROM1"
                     /gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
                     PROML1; RP41; STGD4"
                     /note="prominin 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 4 mRNAs, 68 ESTs, 157
                     long SRA reads, 4 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     2 samples with support for all annotated introns"
                     /db_xref="GeneID:8842"
                     /db_xref="HGNC:HGNC:9454"
                     /db_xref="MIM:604365"
     CDS             399..2996
                     /gene="PROM1"
                     /gene_synonym="AC133; CD133; CORD12; MCDR2; MSTP061;
                     PROML1; RP41; STGD4"
                     /codon_start=1
                     /product="prominin-1 isoform X1"
                     /protein_id="XP_011512197.1"
                     /db_xref="GeneID:8842"
                     /db_xref="HGNC:HGNC:9454"
                     /db_xref="MIM:604365"
                     /translation="MALVLGSLLLLGLCGNSFSGGQPSSTDAPKAWNYELPATNYETQ
                     DSHKAGPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKI
                     VYYEAGIILCCVLGLLFIILMPLVGYFFCMCRCCNKCGGEMHQRQKENGPFLRKCFAI
                     SLLVICIIISIGIFYGFVANHQVRTRIKRSRKLADSNFKDLRTLLNETPEQIKYILAQ
                     YNTTKDKAFTDLNSINSVLGGGILDRLRPNIIPVLDEIKSMATAIKETKEALENMNST
                     LKSLHQQSTQLSSSLTSVKTSLRSSLNDPLCLVHPSSETCNSIRLSLSQLNSNPELRQ
                     LPPVDAELDNVNNVLRTDLDGLVQQGYQSLNDIPDRVQRQTTTVVAGIKRVLNSIGSD
                     IDNVTQRLPIQDILSAFSVYVNNTESYIHRNLPTLEEYDSYWWLGGLVICSLLTLIVI
                     FYYLGLLCGVCGYDRHATPTTRGCVSNTGGVFLMVGVGLSFLFCWILMIIVVLTFVFG
                     ANVEKLICEPYTSKELFRVLDTPYLLNEDWEYYLSGKLFNKSKMKLTFEQVYSDCKKN
                     RGTYGTLHLQNSFNISEHLNINEHTGSISSELESLKVNLNIFLLGAAGRKNLQDFAAC
                     GIDRMNYDSYLAQTGKSPAGVNLLSFAYDLEAKANSLPPGNLRNSLKRDAQTIKTIHQ
                     QRVLPIEQSLSTLYQSVKILQRTGNGLLERVTRILASLDFAQNFITNNTSSVIIEETK
                     KYGRTIIGYFEHYLQWIEFSISEKVASCKPVATALDTAVDVFLCSYIIDPLNLFWFGI
                     GKATVFLLPALIFAVKLAKYYRRMDSEDVYDDVETIPMKNMENGNNGYHKDHVYGIHN
                     PVMTSPSQH"
ORIGIN      
        1 gtagccggcg gccgtggttc cggagcggga gtcggaggtg agtgtgcgaa ctggaccggg
       61 gccccagaga cttcggactc gctctcgggg agaacggtga ccgaggagcc ccggtggagt
      121 tgagctcaga gtattgatgc tagcagaagc agacagaccc cagatagcct tccagctgcg
      181 tgccagggat ggtgccttga gtgaatgacc cccttggaga acattcttcc gcatccctcg
      241 cctcaagcca gcctcagaca gaaaactgaa gattcagcag atccagtgct tcctgctcct
      301 cttctgccca ggaacacgct tgccttcccc aaggcttcca gaagctctga ggcaggaggc
      361 accaagttct acctcatgtt tggaggatct tgctagctat ggccctcgta ctcggctccc
      421 tgttgctgct ggggctgtgc gggaactcct tttcaggagg gcagccttca tccacagatg
      481 ctcctaaggc ttggaattat gaattgcctg caacaaatta tgagacccaa gactcccata
      541 aagctggacc cattggcatt ctctttgaac tagtgcatat ctttctctat gtggtacagc
      601 cgcgtgattt cccagaagat actttgagaa aattcttaca gaaggcatat gaatccaaaa
      661 ttgattatga caagccagaa actgtaatct taggtctaaa gattgtctac tatgaagcag
      721 ggattattct atgctgtgtc ctggggctgc tgtttattat tctgatgcct ctggtggggt
      781 atttcttttg tatgtgtcgt tgctgtaaca aatgtggtgg agaaatgcac cagcgacaga
      841 aggaaaatgg gcccttcctg aggaaatgct ttgcaatctc cctgttggtg atttgtataa
      901 taataagcat tggcatcttc tatggttttg tggcaaatca ccaggtaaga acccggatca
      961 aaaggagtcg gaaactggca gatagcaatt tcaaggactt gcgaactctc ttgaatgaaa
     1021 ctccagagca aatcaaatat atattggccc agtacaacac taccaaggac aaggcgttca
     1081 cagatctgaa cagtatcaat tcagtgctag gaggcggaat tcttgaccga ctgagaccca
     1141 acatcatccc tgttcttgat gagattaagt ccatggcaac agcgatcaag gagaccaaag
     1201 aggcgttgga gaacatgaac agcaccttga agagcttgca ccaacaaagt acacagctta
     1261 gcagcagtct gaccagcgtg aaaactagcc tgcggtcatc tctcaatgac cctctgtgct
     1321 tggtgcatcc atcaagtgaa acctgcaaca gcatcagatt gtctctaagc cagctgaata
     1381 gcaaccctga actgaggcag cttccacccg tggatgcaga acttgacaac gttaataacg
     1441 ttcttaggac agatttggat ggcctggtcc aacagggcta tcaatccctt aatgatatac
     1501 ctgacagagt acaacgccaa accacgactg tcgtagcagg tatcaaaagg gtcttgaatt
     1561 ccattggttc agatatcgac aatgtaactc agcgtcttcc tattcaggat atactctcag
     1621 cattctctgt ttatgttaat aacactgaaa gttacatcca cagaaattta cctacattgg
     1681 aagagtatga ttcatactgg tggctgggtg gcctggtcat ctgctctctg ctgaccctca
     1741 tcgtgatttt ttactacctg ggcttactgt gtggcgtgtg cggctatgac aggcatgcca
     1801 ccccgaccac ccgaggctgt gtctccaaca ccggaggcgt cttcctcatg gttggagttg
     1861 gattaagttt cctcttttgc tggatattga tgatcattgt ggttcttacc tttgtctttg
     1921 gtgcaaatgt ggaaaaactg atctgtgaac cttacacgag caaggaatta ttccgggttt
     1981 tggatacacc ctacttacta aatgaagact gggaatacta tctctctggg aagctattta
     2041 ataaatcaaa aatgaagctc acttttgaac aagtttacag tgactgcaaa aaaaatagag
     2101 gcacttacgg cactcttcac ctgcagaaca gcttcaatat cagtgaacat ctcaacatta
     2161 atgagcatac tggaagcata agcagtgaat tggaaagtct gaaggtaaat cttaatatct
     2221 ttctgttggg tgcagcagga agaaaaaacc ttcaggattt tgctgcttgt ggaatagaca
     2281 gaatgaatta tgacagctac ttggctcaga ctggtaaatc ccccgcagga gtgaatcttt
     2341 tatcatttgc atatgatcta gaagcaaaag caaacagttt gcccccagga aatttgagga
     2401 actccctgaa aagagatgca caaactatta aaacaattca ccagcaacga gtccttccta
     2461 tagaacaatc actgagcact ctataccaaa gcgtcaagat acttcaacgc acagggaatg
     2521 gattgttgga gagagtaact aggattctag cttctctgga ttttgctcag aacttcatca
     2581 caaacaatac ttcctctgtt attattgagg aaactaagaa gtatgggaga acaataatag
     2641 gatattttga acattatctg cagtggatcg agttctctat cagtgagaaa gtggcatcgt
     2701 gcaaacctgt ggccaccgct ctagatactg ctgttgatgt ctttctgtgt agctacatta
     2761 tcgacccctt gaatttgttt tggtttggca taggaaaagc tactgtattt ttacttccgg
     2821 ctctaatttt tgcggtaaaa ctggctaagt actatcgtcg aatggattcg gaggacgtgt
     2881 acgatgatgt tgaaactata cccatgaaaa atatggaaaa tggtaataat ggttatcata
     2941 aagatcatgt atatggtatt cacaatcctg ttatgacaag cccatcacaa cattgatagc
     3001 tgatgttgaa actgcttgag catcaggata ctcaaagtgg aaaggatcac agatttttgg
     3061 tagtttctgg gtctacaagg actttccaaa tccaggagca acgccagtgg caacgtagtg
     3121 actcaggcgg gcaccaaggc aacggcacca ttggtctctg ggtagtgctt taagaatgaa
     3181 cacaatcacg ttatagtcca tggtccatca ctattcaagg atgactccct cccttcctgt
     3241 ctatttttgt tttttacttt tttacactga gtttctattt agacactaca acatatgggg
     3301 tgtttgttcc cattggatgc atttctatca aaactctatc aaatgtgatg gctagattct
     3361 aacatattgc catgtgtgga gtgtgctgaa cacacaccag tttacaggaa agatgcattt
     3421 tgtgtacagt aaacggtgta tatacctttt gttaccacag agttttttaa acaaatgagt
     3481 attataggac tttcttctaa atgagctaaa taagtcacca ttgacttctt ggtgctgttg
     3541 aaaataatcc attttcacta aaagtgtgtg aaacctacag catattcttc acgcagagat
     3601 tttcatctat tatactttat caaagattgg ccatgttcca cttggaaatg gcatgcaaaa
     3661 gcaatcatag agaaacctgc gtaactccat ctgacaaatt caaaagagag agagagatct
     3721 tgagagagaa atgctgttcg ttcaaaagtg gagttgtttt aacagatgcc aattacggtg
     3781 tacagtttaa cagagttttc tgttgcatta cgataaacat taattggagt gcagctaaca
     3841 tgagtatcat cagactagta tcaagtgttc taaaatgaaa tatgagaaga tcctgtcaca
     3901 attcttagat ctggtgtcca gcatggatga aacctttgag tttggtccct aaatttgcat
     3961 gaaagcacaa ggtaaatatt catttgcttc aggagtttca tgttggatct gtcattatca
     4021 aaagtgatca gcaatgaaga actggtcgga caaaatttaa cgttgatgta atgaaattcc
     4081 agatgtaggc attcccccca ggtcttttca tgtgcagatt gcagttctga ttcatttgaa
     4141 taaaaaggaa cttggaaaac a
//
