LOCUS       XM_047446138             834 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein activator of interferon induced
            protein kinase EIF2AK2 (PRKRA), transcript variant X1, mRNA.
ACCESSION   XM_047446138
VERSION     XM_047446138.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..834
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..834
                     /gene="PRKRA"
                     /gene_synonym="DYT16; HSD14; PACT; RAX"
                     /note="protein activator of interferon induced protein
                     kinase EIF2AK2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 17 ESTs, 143 long SRA
                     reads, and 100% coverage of the annotated genomic feature
                     by RNAseq alignments, including 81 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:8575"
                     /db_xref="HGNC:HGNC:9438"
                     /db_xref="MIM:603424"
     CDS             146..721
                     /gene="PRKRA"
                     /gene_synonym="DYT16; HSD14; PACT; RAX"
                     /codon_start=1
                     /product="interferon-inducible double-stranded
                     RNA-dependent protein kinase activator A isoform X1"
                     /protein_id="XP_047302094.1"
                     /db_xref="GeneID:8575"
                     /db_xref="HGNC:HGNC:9438"
                     /db_xref="MIM:603424"
                     /translation="MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGM
                     KTKNIPVYECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKAN
                     ASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYT
                     TICRLESFMETDKCSRTFFRMYLAFLEEFSW"
ORIGIN      
        1 ccctcgctgg agcaacgcaa gcaggaggcg ggggagtcgg aggaggtggc ggcgctggag
       61 ctcctcccgg ggaccagcga cccggggagc gagcacgtcg ctccgcaccg ctcttcctcc
      121 agccgctgag ccgtcccttc tcgccatgtc ccagagcagg caccgcgccg aggccccgcc
      181 gctggagcgc gaggacagtg ggaccttcag tttggggaag atgataacag ctaagccagg
      241 gaaaacaccg attcaggtat tacacgaata cggcatgaag accaagaaca tcccagttta
      301 tgaatgtgaa agatctgatg tgcaaataca cgtgcccact ttcaccttca gagtaaccgt
      361 tggtgacata acctgcacag gtgaaggtac aagtaagaag ctggcgaaac atagagctgc
      421 agaggctgcc ataaacattt tgaaagccaa tgcaagtatt tgctttgcag ttcctgaccc
      481 cttaatgcct gacccttcca agcaaccaaa gaaccagctt aatcctattg gttcattaca
      541 ggaattggct attcatcatg gctggagact tcctgaatat accctttccc aggagggagg
      601 acctgctcat aagagagaat atactacaat ttgcaggcta gagtcattta tggaaactga
      661 caaatgtagt aggacattct ttaggatgta cttggcattc cttgaggaat tctcctggtg
      721 aaaagatcaa cttactgaaa agaagcctcc ttagtattcc aaatacagat tacatccagc
      781 tgcttagtga aattgccaag gaacaaggtt ttaatataac atatttggat atag
//
