LOCUS       XM_011512063            1609 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein activator of interferon induced
            protein kinase EIF2AK2 (PRKRA), transcript variant X2, mRNA.
ACCESSION   XM_011512063
VERSION     XM_011512063.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011512063.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 22% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..1609
                     /gene="PRKRA"
                     /gene_synonym="DYT16; HSD14; PACT; RAX"
                     /note="protein activator of interferon induced protein
                     kinase EIF2AK2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 2 mRNAs, 46 ESTs, 697
                     long SRA reads, 1 Protein, and 90% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     55 samples with support for all annotated introns"
                     /db_xref="GeneID:8575"
                     /db_xref="HGNC:HGNC:9438"
                     /db_xref="MIM:603424"
     CDS             240..926
                     /gene="PRKRA"
                     /gene_synonym="DYT16; HSD14; PACT; RAX"
                     /codon_start=1
                     /product="interferon-inducible double-stranded
                     RNA-dependent protein kinase activator A isoform X2"
                     /protein_id="XP_011510365.1"
                     /db_xref="GeneID:8575"
                     /db_xref="HGNC:HGNC:9438"
                     /db_xref="MIM:603424"
                     /translation="MQVFGELNFFVFSSSKISWLSFAVPDPLMPDPSKQPKNQLNPIG
                     SLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEK
                     FLAKFSNISPENHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIPNTDYIQLL
                     SEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNAL
                     QYLKIIAERK"
ORIGIN      
        1 tttggggaag atgataacag ctaagccagg gaaaacaccg attcaggtat tacacgaata
       61 cggcatgaag accaagaaca tcccagttta tgaatgtgaa agatctgatg tgcaaataca
      121 cgtgcccact ttcaccttca gagtaaccgt tggtgacata acctgcacag gtgaaggtac
      181 aagtaagaag ctggcgaaac atagagctgc agaggctgcc ataaacattt tgaaagccaa
      241 tgcaagtatt tggtgagcta aatttctttg tattcagcag ctcaaaaata tcatggctga
      301 gctttgcagt tcctgacccc ttaatgcctg acccttccaa gcaaccaaag aaccagctta
      361 atcctattgg ttcattacag gaattggcta ttcatcatgg ctggagactt cctgaatata
      421 ccctttccca ggagggagga cctgctcata agagagaata tactacaatt tgcaggctag
      481 agtcatttat ggaaactgga aagggggcat caaaaaagca agccaaaagg aatgctgctg
      541 agaaatttct tgccaaattt agtaatattt ctccagagaa ccacatttct ttaacaaatg
      601 tagtaggaca ttctttagga tgtacttggc attccttgag gaattctcct ggtgaaaaga
      661 tcaacttact gaaaagaagc ctccttagta ttccaaatac agattacatc cagctgctta
      721 gtgaaattgc caaggaacaa ggttttaata taacatattt ggatatagat gaactgagcg
      781 ccaatggaca atatcaatgt cttgctgaac tgtccaccag ccccatcaca gtctgtcatg
      841 gctccggtat ctcctgtggc aatgcacaaa gtgatgcagc tcacaatgct ttgcagtatt
      901 taaagataat agcagaaaga aagtaaatct ggagcaactt aaaaaatctt tcagtagcac
      961 ataaaaagtt cccctctggc cccttcccaa gtaaaacttt taccgtagtg tttatgtctt
     1021 gtttctaaat ctcttcatag attccatcaa cactccagat ttaattatct cctcatagtt
     1081 gttattaagc tctttttaat ggcttcaact ttgtatcagt atactgtatt tataaacttt
     1141 gtaccacaag agagagtgta gcacccattt tacagtgcca tgcacatcag agaaagaaac
     1201 tgcatgtttg ttgttgatga tgaaataaaa atgctagcga cagtctttct tactggtgct
     1261 taagctcttc tttgcacaaa gctttataaa gggaattcaa aggaagccct ttagaattag
     1321 agtcttgagg gacagcacta acaggccttt attaagtatg attgattgtt aaatttcagg
     1381 gaacatgatt ggtctgctgt gtatttgaat tcatgtaaca aagaactgtt acgatgggat
     1441 tctgctcatt ttattaaaaa gctactgact tgactgtcat cctgttcttg ttagccattg
     1501 tgaataagat tttaatgttg ataattctgt tatttacata tctctaattt actttgaaat
     1561 tcaaaggtga aaataaaaaa tgatggccta agtaaaattt acaaacata
//
