LOCUS       XM_047443853            6269 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase D3 (PRKD3), transcript
            variant X3, mRNA.
ACCESSION   XM_047443853
VERSION     XM_047443853.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6269
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6269
                     /gene="PRKD3"
                     /gene_synonym="EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN"
                     /note="protein kinase D3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 5
                     mRNAs, 37 ESTs, 704 long SRA reads, 15 Proteins, and 98%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 78 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:23683"
                     /db_xref="HGNC:HGNC:9408"
                     /db_xref="MIM:607077"
     CDS             922..3594
                     /gene="PRKD3"
                     /gene_synonym="EPK2; nPKC-NU; PKC-NU; PKD3; PRKCN"
                     /codon_start=1
                     /product="serine/threonine-protein kinase D3 isoform X1"
                     /protein_id="XP_047299809.1"
                     /db_xref="GeneID:23683"
                     /db_xref="HGNC:HGNC:9408"
                     /db_xref="MIM:607077"
                     /translation="MSANNSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGS
                     FSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGF
                     FGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSALATVEDFQIRPHTLYVH
                     SYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRRLSNVSLP
                     GPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRPIWMEKMVMCRVKVPHTFAV
                     HSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSL
                     GTDTDIPMDIDNNDINSDSSRGLDDTEEPSPPEDKMFFLDPSDLDVERDEEAVKTISP
                     STSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQN
                     ESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGENNGDSSHNP
                     VLAATGVGLDVAQSWEKAIRQALMPVTPQASVCTSPGQGKDHKDLSTSISVSNCQIQE
                     NVDISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEV
                     AILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQ
                     ILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTP
                     AYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPW
                     REISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGERYITHE
                     SDDARWEIHAYTHNLVYPKHFIMAPNPDDMEEDP"
ORIGIN      
        1 gccctccggc cccaggacgg gacggggagg gagggaggaa ggggcgccgg aggcgggcgg
       61 gatcctgcga ggcgcgtgaa gcctcgctgg cgcctcgtcc ggtactcaga cgctggcggg
      121 cgcagtttct cacgacgggc cgagcctgcc actaaatgct ttgtggtcta cagccacacc
      181 accccaaatg tgcctgatct tgtctgatct tggaagctaa gcattgttgg gcctagttag
      241 gacctggata ggagaaatcc cttatggcta actatatgtc agaaagcatc agcttttctc
      301 gatggaccca ttcatctaat gaaatatgcc tgtactattt taaaaagctt tgtatttcgt
      361 catagaaaag ttcatccccc cagaatgaaa atgaggacat ttgagaaggt gatttaaggt
      421 gtggacattt gagaaggtgt cctatcaaat tagtaaacca aaggaaaagt actgaataga
      481 ttaatccaaa acacttactg ttttttaaac gaagaggatt tcaccttgac agaaaaacaa
      541 cttttattca atatgtattt cctgaaatta aagagacaag tacagactga aaggaaaata
      601 gattcgtaaa taagctacgt caactctatc ctgctgagga tagctcagtg atgttaaatc
      661 ctttacaaat ccctggttgt cttcctacag acaagactgc tttttgatgg gactgatatt
      721 aagagaaata ggacctttgg ggcattcaac tccttgataa aacttaaaag tatcggcatg
      781 agtggcttaa cagaggaaat aaagaagttt tcaactaaat ccaaaagtgc ggtcattttc
      841 tttactgctg ttattttaaa aacctcttca taaccattga aaaagaatcg acaactattt
      901 taaaagatta aagaaaggca gatgtctgca aataattccc ctccatcagc ccagaagtct
      961 gtattaccca cagctattcc tgctgtgctt ccagctgctt ctccgtgttc aagtcctaag
     1021 acgggactct ctgcccgact ctctaatgga agcttcagtg caccatcact caccaactcc
     1081 agaggctcag tgcatacagt ttcatttcta ctgcaaattg gcctcacacg ggagagtgtt
     1141 accattgaag cccaggaact gtctttatct gctgtcaagg atcttgtgtg ctccatagtt
     1201 tatcaaaagt ttccagagtg tggattcttt ggcatgtatg acaaaattct tctctttcgc
     1261 catgacatga actcagaaaa cattttgcag ctgattacct cagcagatga aatacatgaa
     1321 ggagacctag tggaagtggt tctttcagct ttagccacag tagaagactt ccagattcgt
     1381 ccacatactc tctatgtaca ttcttacaaa gctcctactt tctgtgatta ctgtggtgag
     1441 atgctctggg gattggtacg tcaaggactg aaatgtgaag gctgtggatt aaattaccat
     1501 aaacgatgtg ccttcaagat tccaaataac tgtagtggag taagaaagag acgtctgtca
     1561 aatgtatctt taccaggacc cggcctctca gttccaagac ccctacagcc tgaatatgta
     1621 gcccttccca gtgaagagtc acatgtccac caggaaccaa gtaagagaat tccttcttgg
     1681 agtggtcgcc caatctggat ggaaaagatg gtaatgtgca gagtgaaagt tccacacaca
     1741 tttgctgttc actcttacac ccgtcccacg atatgtcagt actgcaagcg gttactgaaa
     1801 ggcctctttc gccaaggaat gcagtgtaaa gattgcaaat tcaactgcca taaacgctgt
     1861 gcatcaaaag taccaagaga ctgccttgga gaggttactt tcaatggaga accttccagt
     1921 ctgggaacag atacagatat accaatggat attgacaata atgacataaa tagtgatagt
     1981 agtcggggtt tggatgacac agaagagcca tcacccccag aagataagat gttcttcttg
     2041 gatccatctg atctcgatgt ggaaagagat gaagaagccg ttaaaacaat cagtccatca
     2101 acaagcaata atattccgct aatgagggtt gtacaatcca tcaagcacac aaagaggaag
     2161 agcagcacaa tggtgaagga agggtggatg gtccattaca ccagcaggga taacctgaga
     2221 aagaggcatt attggagact tgacagcaaa tgtctaacat tatttcagaa tgaatctgga
     2281 tcaaagtatt ataaggaaat tccactttca gaaattctcc gcatatcttc accacgagat
     2341 ttcacaaaca tttcacaagg cagcaatcca cactgttttg aaatcattac tgatactatg
     2401 gtatacttcg ttggtgagaa caatggggac agctctcata atcctgttct tgctgccact
     2461 ggagttggac ttgatgtagc acagagctgg gaaaaagcaa ttcgccaagc cctcatgcct
     2521 gttactcctc aagcaagtgt ttgcacttct ccagggcaag ggaaagatca caaagatttg
     2581 tctacaagta tctctgtatc taattgtcag attcaggaga atgtggatat cagtactgtt
     2641 taccagatct ttgcagatga ggtgcttggt tcaggccagt ttggcatcgt ttatggagga
     2701 aaacatagaa agactgggag ggatgtggct attaaagtaa ttgataagat gagattcccc
     2761 acaaaacaag aaagtcaact ccgtaatgaa gtggctattt tacagaattt gcaccatcct
     2821 gggattgtaa acctggaatg tatgtttgaa accccagaac gagtctttgt agtaatggaa
     2881 aagctgcatg gagatatgtt ggaaatgatt ctatccagtg agaaaagtcg gcttccagaa
     2941 cgaattacta aattcatggt cacacagata cttgttgctt tgaggaatct gcattttaag
     3001 aatattgtgc actgtgattt aaagccagaa aatgtgctgc ttgcatcagc agagccattt
     3061 cctcaggtga agctgtgtga ctttggattt gcacgcatca ttggtgaaaa gtcattcagg
     3121 agatctgtgg taggaactcc agcatactta gcccctgaag ttctccggag caaaggttac
     3181 aaccgttccc tagatatgtg gtcagtggga gttatcatct atgtgagcct cagtggcaca
     3241 tttcctttta atgaggatga agatataaat gaccaaatcc aaaatgctgc atttatgtac
     3301 ccaccaaatc catggagaga aatttctggt gaagcaattg atctgataaa caatctgctt
     3361 caagtgaaga tgagaaaacg ttacagtgtt gacaaatctc ttagtcatcc ctggctacag
     3421 gactatcaga cttggcttga ccttagagaa tttgaaactc gcattggaga acgttacatt
     3481 acacatgaaa gtgatgatgc tcgctgggaa atacatgcat acacacataa ccttgtatac
     3541 ccaaagcact tcattatggc tcctaatcca gatgatatgg aagaagatcc ttaatcactg
     3601 agctaaccta aataaggaag gatttcattt tatggactga tattttgctg tgtaacttgt
     3661 tctttgtaga ttgtcatctg cagtgctgca aagatatgaa gaaatatgat aacgaataag
     3721 tgacaccagt actgtagttc ataatgagta ggtacaggcg ggaaactgaa taataagaag
     3781 tcataatgga atcaaggtga agctttttat aaactttttt agcctaagca ataactggtt
     3841 ttgtattttt tcttaatcct tcactttaat acaataggct cacttaattt gtcttcccat
     3901 ttctctttat atatatatat ataaatataa atatatgttt gtttgttttt ttaatgaaaa
     3961 acaagtcaag ctagcatcca gttactatat agcttggcta aattatacaa gacttacaag
     4021 attgattact cgacaggctt gtatttaaga ggtaactgtg aggttaccat tatgtgatgt
     4081 tactataagg acttttaaca ttggtttaac aaaccataga ggcattgaag ggtttttctt
     4141 agatgcctag aaaaagcgca ctgggctgtt ttacctttct tttttaggtc aatcaagact
     4201 ccaaaatagt gattcctaac ctttttggag ttgctctgct actctgaata tgttctatac
     4261 agcataagga ttgtcacctt ctgtgtgttg caacagcttc taagataatt agggacaaat
     4321 gatgttacaa aaggaagagt actgctggtc taagtgctga gttgtatgtc tttgcatagc
     4381 tccactctgc tgctaaatat gcatgttctg actgacacca tcttgatgcc agtactggat
     4441 tccagcattc agcaggtgca gatctcggct ttacacaatt tatctttacc tagggttcag
     4501 tcagtaattt ctgcttttta gcagggccag tgcagggtca gttaatgcta cagttactgt
     4561 atagcaaaca gtatcctttt ttctccttcc cctagcctat tgggctttgc agatatctgg
     4621 agtgttttaa agtcaattat tttaagcagt ttgaggggat gtgtaggagt ggagcatgaa
     4681 acagtttata aggctggggc tgtattatca gcacagcaaa ttaaagaatg aaagaagtac
     4741 ttctttttac atttcagctc cagcagccag ctatttaaaa aatattttta aatatcttcc
     4801 ccaaagttta agatgtggga ccatctactt gtaagaaaca gtggcttatt tcttcatttc
     4861 tcagtaatca ttgtaaacct tttttttttt cttctccact ctaacaaaag taaaagaaca
     4921 aaacttttgc tgaggtcttg gactccacta cttgttagtt atgttggcct ggacagatgg
     4981 caggtctgtc ggcagttcct cagtctgtaa aatgaagatt atcattcttg cctctccctt
     5041 tgtcacagtg ttgtcgtgaa gatcagatat gtatgaatgc agtcaaataa actaaaaact
     5101 aggaaagtgt taactatcgt tgcccaccga atttgaggta gcaaaaaaaa aaaagaatgt
     5161 tctggtacat gaacagactg agaaggcctt tcgacatccc tgaagctagt ctcctgtcta
     5221 gactaaaaat atccttgaaa gaatagtagc aaacagtatg cagtactcct gtgttctaag
     5281 ttcttttatg ttttagttta ccctcacagc agccatagtg ttaagtcatt atgagcttca
     5341 tcttaaagat aagaaaactg aggcaagggg agattaactt actgccaaat ttcaaacagt
     5401 tagtagtatt tgagaccagt agtatggctc taatcttacc cttagccctc ccaaccatta
     5461 tgctgtacta tctacccata aatacctcca ggaaacattc ccctcttggt aatttgtcct
     5521 tctatagaag cttcaaagat taaatcaaat taattttcaa aaaaaatttt tttttagaaa
     5581 tgttattttc cctgtgatag aggatgactt cccagtttca ccaaagtctg tttatatcaa
     5641 cacacacaaa atggaataat tctgagtcac taggcaatca atctactgtg gttttactat
     5701 gtaaggtgaa aattaactgg aacgatgttt gtttgctata cttacatagt caaactttac
     5761 aagccatgaa attaattgca ctctttgtat ttgttgttaa atgcctaaga agttttctaa
     5821 aaattttgta aaggcactgt cagagaatct ggagttgaat gattattcca gatactgtat
     5881 aacctgcata actttttgtc tttaagtcgt gtttgtaaaa gaagtaattg ctagaaacat
     5941 ttgataatgt acaaagtagt ctataatgac tgttcagtac atttttaata tttttttggt
     6001 tatatccaac tttttgtaaa tatactggaa gcttgataat aaaatgtatt tcctatcacc
     6061 atacttttcc atgtgaaaac ctgagcctat ttctagtata agtatccaaa gaaaagtttg
     6121 acctggttgt gttattttac cagaccttgg taaaagaact attttggaaa cagtatttgt
     6181 aaatggaact aatgctatat ttaaaaacac tgattttttt ttaacctgcc aaaaataaaa
     6241 aaaagctcat tttataattt tctactaaa
//
