LOCUS       XM_047425323            2035 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X17, mRNA.
ACCESSION   XM_047425323
VERSION     XM_047425323.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2035
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2035
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 137 ESTs, 472 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             396..1649
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X11"
                     /protein_id="XP_047281279.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDD
                     SEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKK
                     ELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLRRLSPCRLFLVIEYVNG
                     GDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLT
                     DYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPF
                     DIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGF
                     SDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDEDAI
                     KRIDQSEFEGFEYINPLLLSTEESV"
ORIGIN      
        1 agaacatcgc tcggtgccag acaggcagga cgcagcgggc tggcctgcgg ggctcactgc
       61 tgccccccgg ggccgagcac gaaagggaga gttggagggc gcttcctcgc cgggtgttgc
      121 ggtgtgagcg gggactggtg agtgtgtgct gtcttcagag agagaagagc agttttcagg
      181 aatctatcta ccgccgggga gccagaagat ggaggaagct gtaccgtgcc aacggccacc
      241 tcttccaagc caagcgcttt aacaggagag cgtactgcgg tcagtgcagc gagaggatat
      301 ggggcctcgc gaggcaaggc tacaggtgca tcaactgcaa actgctggtc cataagcgct
      361 gccacggcct cgtcccgctg acctgcagga agcatatgga ttctgtcatg ccttcccaag
      421 agcctccagt agacgacaag aacgaggacg ccgaccttcc ttccgaggag acagatggaa
      481 ttgcttacat ttcctcatcc cggaagcatg acagcattaa agacgactcg gaggacctta
      541 agccagttat cgatgggatg gatggaatca aaatctctca ggggcttggg ctgcaggact
      601 ttgacctaat cagagtcatc gggcgcggga gctacgccaa ggttctcctg gtgcggttga
      661 agaagaatga ccaaatttac gccatgaaag tggtgaagaa agagctggtg catgatgacg
      721 aggatattga ctgggtacag acagagaagc acgtgtttga gcaggcatcc agcaacccct
      781 tcctggtcgg attacactcc tgcttccaga cgacaagtcg cctccggcgc ctctctccct
      841 gcaggttgtt cctggtcatt gagtacgtca acggcgggga cctgatgttc cacatgcaga
      901 ggcagaggaa gctccctgag gagcacgcca ggttctacgc ggccgagatc tgcatcgccc
      961 tcaacttcct gcacgagagg gggatcatct acagggacct gaagctggac aacgtcctcc
     1021 tggatgcgga cgggcacatc aagctcacag actacggcat gtgcaaggaa ggcctgggcc
     1081 ctggtgacac aacgagcact ttctgcggaa ccccgaatta catcgccccc gaaatcctgc
     1141 ggggagagga gtacgggttc agcgtggact ggtgggcgct gggagtcctc atgtttgaga
     1201 tgatggccgg gcgctccccg ttcgacatca tcaccgacaa cccggacatg aacacagagg
     1261 actacctttt ccaagtgatc ctggagaagc ccatccggat cccccggttc ctgtccgtca
     1321 aagcctccca tgttttaaaa ggatttttaa ataaggaccc caaagagagg ctcggctgcc
     1381 ggccacagac tggattttct gacatcaagt cccacgcgtt cttccgcagc atagactggg
     1441 acttgctgga gaagaagcag gcgctccctc cattccagcc acagatcaca gacgactacg
     1501 gtctggacaa ctttgacaca cagttcacca gcgagcccgt gcagctgacc ccagacgatg
     1561 aggatgccat aaagaggatc gaccagtcag agttcgaagg ctttgagtat atcaacccat
     1621 tattgctgtc caccgaggag tcggtgtgag gccgcgtgcg tctctgtcgt ggacacgcgt
     1681 gattgaccct ttaactgtat ccttaaccac cgcatatgca tgccaggctg ggcacggctc
     1741 cgagggcggc cagggacaga cgcttgcgcc gagaccgcag agggaagcgt cagcgggcgc
     1801 tgctgggagc agaacagtcc ctcacacctg ggcccgggca ggccagcttc gtgctggagg
     1861 aacttgctgc tgtgcctgcg tcgcggcgga tccgcgggga ccctgccgag ggggctgtca
     1921 tgcggtttcc aaggtgcaca ttttccacgg aaacagaact cgatgcactg acctgctccg
     1981 ccaggaaagt gagcgtgtag cgtcctgagg aataaaatgt tccgatgatg tggaa
//
