LOCUS       XM_047425262            2351 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X6, mRNA.
ACCESSION   XM_047425262
VERSION     XM_047425262.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2351
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2351
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 80 ESTs, 977 long SRA reads, 12 Proteins, and 98%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 26 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             325..1965
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X6"
                     /protein_id="XP_047281218.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MCRLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLARQCRDEG
                     LIIHVFPSTPEQPGLPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCS
                     ERIWGLARQGYRCINCKLLVHKRCHGLVPLTCRKHMDSVMPSQEPPVDDKNEDADLPS
                     EETDGIAYISSSRKHDSIKDDSEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYA
                     KVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQT
                     TSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLD
                     NVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALG
                     VLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKD
                     PKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDTQFTS
                     EPVQLTPDDEDAIKRIDQSEFEGFEYINPLLLSTEESV"
ORIGIN      
        1 ggctcagccg tcggggctcc tgcgcgagag ggagagaggg aaggggcggc gaggtcgctg
       61 cgggcccggg gctgtcgcgg gaggtcctcg gtccccgccc gtgagcgtca cccgcggaca
      121 cgtcgtggac agcgcgggct ccttccccgg gaccgggttt ccctggggtc ggccccgcgc
      181 cgcgagctcc tcggcccggt cattgtggta gacgttttcg ctggaaagtt gggcggggac
      241 gttccggccg caaacctgga catcttcatc accagcgtgg acgccgccac gaccttcgag
      301 gagctctgtg aggaagtgag agacatgtgt cgtctgcacc agcagcaccc gctcaccctc
      361 aagtgggtgg acagcgaagg tgacccttgc acggtgtcct cccagatgga gctggaagag
      421 gctttccgcc tggcccgtca gtgcagggat gaaggcctca tcattcatgt tttcccgagc
      481 acccctgagc agcctggcct gccatgtccg ggagaagaca aatctatcta ccgccgggga
      541 gccagaagat ggaggaagct gtaccgtgcc aacggccacc tcttccaagc caagcgcttt
      601 aacaggagag cgtactgcgg tcagtgcagc gagaggatat ggggcctcgc gaggcaaggc
      661 tacaggtgca tcaactgcaa actgctggtc cataagcgct gccacggcct cgtcccgctg
      721 acctgcagga agcatatgga ttctgtcatg ccttcccaag agcctccagt agacgacaag
      781 aacgaggacg ccgaccttcc ttccgaggag acagatggaa ttgcttacat ttcctcatcc
      841 cggaagcatg acagcattaa agacgactcg gaggacctta agccagttat cgatgggatg
      901 gatggaatca aaatctctca ggggcttggg ctgcaggact ttgacctaat cagagtcatc
      961 gggcgcggga gctacgccaa ggttctcctg gtgcggttga agaagaatga ccaaatttac
     1021 gccatgaaag tggtgaagaa agagctggtg catgatgacg aggatattga ctgggtacag
     1081 acagagaagc acgtgtttga gcaggcatcc agcaacccct tcctggtcgg attacactcc
     1141 tgcttccaga cgacaagtcg gttgttcctg gtcattgagt acgtcaacgg cggggacctg
     1201 atgttccaca tgcagaggca gaggaagctc cctgaggagc acgccaggtt ctacgcggcc
     1261 gagatctgca tcgccctcaa cttcctgcac gagaggggga tcatctacag ggacctgaag
     1321 ctggacaacg tcctcctgga tgcggacggg cacatcaagc tcacagacta cggcatgtgc
     1381 aaggaaggcc tgggccctgg tgacacaacg agcactttct gcggaacccc gaattacatc
     1441 gcccccgaaa tcctgcgggg agaggagtac gggttcagcg tggactggtg ggcgctggga
     1501 gtcctcatgt ttgagatgat ggccgggcgc tccccgttcg acatcatcac cgacaacccg
     1561 gacatgaaca cagaggacta ccttttccaa gtgatcctgg agaagcccat ccggatcccc
     1621 cggttcctgt ccgtcaaagc ctcccatgtt ttaaaaggat ttttaaataa ggaccccaaa
     1681 gagaggctcg gctgccggcc acagactgga ttttctgaca tcaagtccca cgcgttcttc
     1741 cgcagcatag actgggactt gctggagaag aagcaggcgc tccctccatt ccagccacag
     1801 atcacagacg actacggtct ggacaacttt gacacacagt tcaccagcga gcccgtgcag
     1861 ctgaccccag acgatgagga tgccataaag aggatcgacc agtcagagtt cgaaggcttt
     1921 gagtatatca acccattatt gctgtccacc gaggagtcgg tgtgaggccg cgtgcgtctc
     1981 tgtcgtggac acgcgtgatt gaccctttaa ctgtatcctt aaccaccgca tatgcatgcc
     2041 aggctgggca cggctccgag ggcggccagg gacagacgct tgcgccgaga ccgcagaggg
     2101 aagcgtcagc gggcgctgct gggagcagaa cagtccctca cacctgggcc cgggcaggcc
     2161 agcttcgtgc tggaggaact tgctgctgtg cctgcgtcgc ggcggatccg cggggaccct
     2221 gccgaggggg ctgtcatgcg gtttccaagg tgcacatttt ccacggaaac agaactcgat
     2281 gcactgacct gctccgccag gaaagtgagc gtgtagcgtc ctgaggaata aaatgttccg
     2341 atgatgtgga a
//
