LOCUS       XM_024448397            1668 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X24, mRNA.
ACCESSION   XM_024448397
VERSION     XM_024448397.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024448397.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1668
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..1668
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     ESTs, 8 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 8 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             185..1285
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X16"
                     /protein_id="XP_024304165.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMK
                     VVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLRRLSPCRLFLVIE
                     YVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGH
                     IKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAG
                     RSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRP
                     QTGFSDIKSHAFFRSIDWDLMHRQLRCTDARTTWTPRRCGRTDDMDAQTMWMHGRRRH
                     TDDSSTDDSDARTPRRRGRTDDADAQMTWTHR"
ORIGIN      
        1 ccatctgctc tgcaggggtc attgtcttca agcctggcca cccttccctg gggctgggga
       61 tgaggctctc cagggcctcc tctcaatccc cggcagagat gagcaggttg cttacatttc
      121 ctcatcccgg aagcatgaca gcattaaaga cgactcggag gaccttaagc cagttatcga
      181 tgggatggat ggaatcaaaa tctctcaggg gcttgggctg caggactttg acctaatcag
      241 agtcatcggg cgcgggagct acgccaaggt tctcctggtg cggttgaaga agaatgacca
      301 aatttacgcc atgaaagtgg tgaagaaaga gctggtgcat gatgacgagg atattgactg
      361 ggtacagaca gagaagcacg tgtttgagca ggcatccagc aaccccttcc tggtcggatt
      421 acactcctgc ttccagacga caagtcgcct ccggcgcctc tctccctgca ggttgttcct
      481 ggtcattgag tacgtcaacg gcggggacct gatgttccac atgcagaggc agaggaagct
      541 ccctgaggag cacgccaggt tctacgcggc cgagatctgc atcgccctca acttcctgca
      601 cgagaggggg atcatctaca gggacctgaa gctggacaac gtcctcctgg atgcggacgg
      661 gcacatcaag ctcacagact acggcatgtg caaggaaggc ctgggccctg gtgacacaac
      721 gagcactttc tgcggaaccc cgaattacat cgcccccgaa atcctgcggg gagaggagta
      781 cgggttcagc gtggactggt gggcgctggg agtcctcatg tttgagatga tggccgggcg
      841 ctccccgttc gacatcatca ccgacaaccc ggacatgaac acagaggact accttttcca
      901 agtgatcctg gagaagccca tccggatccc ccggttcctg tccgtcaaag cctcccatgt
      961 tttaaaagga tttttaaata aggaccccaa agagaggctc ggctgccggc cacagactgg
     1021 attttctgac atcaagtccc acgcgttctt ccgcagcata gactgggact tgatgcacag
     1081 acaactcaga tgcacagacg cccggacgac gtggacaccc agacgatgtg gacgcacaga
     1141 cgacatggac gcacagacga tgtggatgca cggacgacgt agacacacgg atgactcatc
     1201 cacagatgac tcagatgcac ggacacccag acgacgcgga cgcacagacg acgcggacgc
     1261 acagatgacg tggacgcaca gatgacgtgg acgcacggac gacgtggatg catggacgac
     1321 gtggacgcac agatgacctg gacgcacgga cgacgtggac gcacggatga ctcagatccc
     1381 cagacgactc agatgcacgg acacccagat gacatggatg cacggacgac tcagatccac
     1441 agatgactca aacgcacaga tgactgggat gctcagatga ccgctgctgt gctgccaccc
     1501 cagggctctc tgggcgtttc ctgtggtttg ggcaccagga gcctgggagt cccatgctgc
     1561 ccccagggca ctacctcctg ggcccagccc tgcatccggt ggcagggctc accgtcatca
     1621 ccccaacagt gcagggtggt ctcagggacc tcctctcatc attgccaa
//
