LOCUS       XM_024448391            2041 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X12, mRNA.
ACCESSION   XM_024448391
VERSION     XM_024448391.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_024448391.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2041
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2041
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 92
                     ESTs, 25 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 2 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             396..1658
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X10"
                     /protein_id="XP_024304159.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDD
                     SEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKK
                     ELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLRRLSPCRLFLVIEYVNG
                     GDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLT
                     DYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPF
                     DIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGF
                     SDIKSHAFFRSIDWDLMHRQLRCTDARTTWTPRRCGRTDDMDAQTMWMHGRRRHTDDS
                     STDDSDARTPRRRGRTDDADAQMTWTHR"
ORIGIN      
        1 agaacatcgc tcggtgccag acaggcagga cgcagcgggc tggcctgcgg ggctcactgc
       61 tgccccccgg ggccgagcac gaaagggaga gttggagggc gcttcctcgc cgggtgttgc
      121 ggtgtgagcg gggactggtg agtgtgtgct gtcttcagag agagaagagc agttttcagg
      181 aatctatcta ccgccgggga gccagaagat ggaggaagct gtaccgtgcc aacggccacc
      241 tcttccaagc caagcgcttt aacaggagag cgtactgcgg tcagtgcagc gagaggatat
      301 ggggcctcgc gaggcaaggc tacaggtgca tcaactgcaa actgctggtc cataagcgct
      361 gccacggcct cgtcccgctg acctgcagga agcatatgga ttctgtcatg ccttcccaag
      421 agcctccagt agacgacaag aacgaggacg ccgaccttcc ttccgaggag acagatggaa
      481 ttgcttacat ttcctcatcc cggaagcatg acagcattaa agacgactcg gaggacctta
      541 agccagttat cgatgggatg gatggaatca aaatctctca ggggcttggg ctgcaggact
      601 ttgacctaat cagagtcatc gggcgcggga gctacgccaa ggttctcctg gtgcggttga
      661 agaagaatga ccaaatttac gccatgaaag tggtgaagaa agagctggtg catgatgacg
      721 aggatattga ctgggtacag acagagaagc acgtgtttga gcaggcatcc agcaacccct
      781 tcctggtcgg attacactcc tgcttccaga cgacaagtcg cctccggcgc ctctctccct
      841 gcaggttgtt cctggtcatt gagtacgtca acggcgggga cctgatgttc cacatgcaga
      901 ggcagaggaa gctccctgag gagcacgcca ggttctacgc ggccgagatc tgcatcgccc
      961 tcaacttcct gcacgagagg gggatcatct acagggacct gaagctggac aacgtcctcc
     1021 tggatgcgga cgggcacatc aagctcacag actacggcat gtgcaaggaa ggcctgggcc
     1081 ctggtgacac aacgagcact ttctgcggaa ccccgaatta catcgccccc gaaatcctgc
     1141 ggggagagga gtacgggttc agcgtggact ggtgggcgct gggagtcctc atgtttgaga
     1201 tgatggccgg gcgctccccg ttcgacatca tcaccgacaa cccggacatg aacacagagg
     1261 actacctttt ccaagtgatc ctggagaagc ccatccggat cccccggttc ctgtccgtca
     1321 aagcctccca tgttttaaaa ggatttttaa ataaggaccc caaagagagg ctcggctgcc
     1381 ggccacagac tggattttct gacatcaagt cccacgcgtt cttccgcagc atagactggg
     1441 acttgatgca cagacaactc agatgcacag acgcccggac gacgtggaca cccagacgat
     1501 gtggacgcac agacgacatg gacgcacaga cgatgtggat gcacggacga cgtagacaca
     1561 cggatgactc atccacagat gactcagatg cacggacacc cagacgacgc ggacgcacag
     1621 acgacgcgga cgcacagatg acgtggacgc acagatgacg tggacgcacg gacgacgtgg
     1681 atgcatggac gacgtggacg cacagatgac ctggacgcac ggacgacgtg gacgcacgga
     1741 tgactcagat ccccagacga ctcagatgca cggacaccca gatgacatgg atgcacggac
     1801 gactcagatc cacagatgac tcaaacgcac agatgactgg gatgctcaga tgaccgctgc
     1861 tgtgctgcca ccccagggct ctctgggcgt ttcctgtggt ttgggcacca ggagcctggg
     1921 agtcccatgc tgcccccagg gcactacctc ctgggcccag ccctgcatcc ggtggcaggg
     1981 ctcaccgtca tcaccccaac agtgcagggt ggtctcaggg acctcctctc atcattgcca
     2041 a
//
