LOCUS       XM_017001802            1643 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X25, mRNA.
ACCESSION   XM_017001802
VERSION     XM_017001802.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017001802.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1643
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..1643
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 10
                     ESTs, 69 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 17 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             184..1260
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X17"
                     /protein_id="XP_016857291.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMK
                     VVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLM
                     FHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGM
                     CKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIIT
                     DNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIK
                     SHAFFRSIDWDLMHRQLRCTDARTTWTPRRCGRTDDMDAQTMWMHGRRRHTDDSSTDD
                     SDARTPRRRGRTDDADAQMTWTHR"
ORIGIN      
        1 catctgctct gcaggggtca ttgtcttcaa gcctggccac ccttccctgg ggctggggat
       61 gaggctctcc agggcctcct ctcaatcccc ggcagagatg agcaggttgc ttacatttcc
      121 tcatcccgga agcatgacag cattaaagac gactcggagg accttaagcc agttatcgat
      181 gggatggatg gaatcaaaat ctctcagggg cttgggctgc aggactttga cctaatcaga
      241 gtcatcgggc gcgggagcta cgccaaggtt ctcctggtgc ggttgaagaa gaatgaccaa
      301 atttacgcca tgaaagtggt gaagaaagag ctggtgcatg atgacgagga tattgactgg
      361 gtacagacag agaagcacgt gtttgagcag gcatccagca accccttcct ggtcggatta
      421 cactcctgct tccagacgac aagtcggttg ttcctggtca ttgagtacgt caacggcggg
      481 gacctgatgt tccacatgca gaggcagagg aagctccctg aggagcacgc caggttctac
      541 gcggccgaga tctgcatcgc cctcaacttc ctgcacgaga gggggatcat ctacagggac
      601 ctgaagctgg acaacgtcct cctggatgcg gacgggcaca tcaagctcac agactacggc
      661 atgtgcaagg aaggcctggg ccctggtgac acaacgagca ctttctgcgg aaccccgaat
      721 tacatcgccc ccgaaatcct gcggggagag gagtacgggt tcagcgtgga ctggtgggcg
      781 ctgggagtcc tcatgtttga gatgatggcc gggcgctccc cgttcgacat catcaccgac
      841 aacccggaca tgaacacaga ggactacctt ttccaagtga tcctggagaa gcccatccgg
      901 atcccccggt tcctgtccgt caaagcctcc catgttttaa aaggattttt aaataaggac
      961 cccaaagaga ggctcggctg ccggccacag actggatttt ctgacatcaa gtcccacgcg
     1021 ttcttccgca gcatagactg ggacttgatg cacagacaac tcagatgcac agacgcccgg
     1081 acgacgtgga cacccagacg atgtggacgc acagacgaca tggacgcaca gacgatgtgg
     1141 atgcacggac gacgtagaca cacggatgac tcatccacag atgactcaga tgcacggaca
     1201 cccagacgac gcggacgcac agacgacgcg gacgcacaga tgacgtggac gcacagatga
     1261 cgtggacgca cggacgacgt ggatgcatgg acgacgtgga cgcacagatg acctggacgc
     1321 acggacgacg tggacgcacg gatgactcag atccccagac gactcagatg cacggacacc
     1381 cagatgacat ggatgcacgg acgactcaga tccacagatg actcaaacgc acagatgact
     1441 gggatgctca gatgaccgct gctgtgctgc caccccaggg ctctctgggc gtttcctgtg
     1501 gtttgggcac caggagcctg ggagtcccat gctgccccca gggcactacc tcctgggccc
     1561 agccctgcat ccggtggcag ggctcaccgt catcacccca acagtgcagg gtggtctcag
     1621 ggacctcctc tcatcattgc caa
//
