LOCUS       XM_017001797            1768 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X18, mRNA.
ACCESSION   XM_017001797
VERSION     XM_017001797.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017001797.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1768
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..1768
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     ESTs, 8 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 11 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             135..1385
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X12"
                     /protein_id="XP_016857286.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDDSEDL
                     KPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVH
                     DDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLRRLSPCRLFLVIEYVNGGDLM
                     FHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGM
                     CKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIIT
                     DNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIK
                     SHAFFRSIDWDLMHRQLRCTDARTTWTPRRCGRTDDMDAQTMWMHGRRRHTDDSSTDD
                     SDARTPRRRGRTDDADAQMTWTHR"
ORIGIN      
        1 aggatgcagc tttgggacag gggagatgac caagcattgt gcaaaatatc ccgttgtata
       61 aagcacttgg tggaaaggtc atggcctgca gtaccgagtg gccacctccg tctgcagaat
      121 cataggattc tgtcatgcct tcccaagagc ctccagtaga cgacaagaac gaggacgccg
      181 accttccttc cgaggagaca gatggaattg cttacatttc ctcatcccgg aagcatgaca
      241 gcattaaaga cgactcggag gaccttaagc cagttatcga tgggatggat ggaatcaaaa
      301 tctctcaggg gcttgggctg caggactttg acctaatcag agtcatcggg cgcgggagct
      361 acgccaaggt tctcctggtg cggttgaaga agaatgacca aatttacgcc atgaaagtgg
      421 tgaagaaaga gctggtgcat gatgacgagg atattgactg ggtacagaca gagaagcacg
      481 tgtttgagca ggcatccagc aaccccttcc tggtcggatt acactcctgc ttccagacga
      541 caagtcgcct ccggcgcctc tctccctgca ggttgttcct ggtcattgag tacgtcaacg
      601 gcggggacct gatgttccac atgcagaggc agaggaagct ccctgaggag cacgccaggt
      661 tctacgcggc cgagatctgc atcgccctca acttcctgca cgagaggggg atcatctaca
      721 gggacctgaa gctggacaac gtcctcctgg atgcggacgg gcacatcaag ctcacagact
      781 acggcatgtg caaggaaggc ctgggccctg gtgacacaac gagcactttc tgcggaaccc
      841 cgaattacat cgcccccgaa atcctgcggg gagaggagta cgggttcagc gtggactggt
      901 gggcgctggg agtcctcatg tttgagatga tggccgggcg ctccccgttc gacatcatca
      961 ccgacaaccc ggacatgaac acagaggact accttttcca agtgatcctg gagaagccca
     1021 tccggatccc ccggttcctg tccgtcaaag cctcccatgt tttaaaagga tttttaaata
     1081 aggaccccaa agagaggctc ggctgccggc cacagactgg attttctgac atcaagtccc
     1141 acgcgttctt ccgcagcata gactgggact tgatgcacag acaactcaga tgcacagacg
     1201 cccggacgac gtggacaccc agacgatgtg gacgcacaga cgacatggac gcacagacga
     1261 tgtggatgca cggacgacgt agacacacgg atgactcatc cacagatgac tcagatgcac
     1321 ggacacccag acgacgcgga cgcacagacg acgcggacgc acagatgacg tggacgcaca
     1381 gatgacgtgg acgcacggac gacgtggatg catggacgac gtggacgcac agatgacctg
     1441 gacgcacgga cgacgtggac gcacggatga ctcagatccc cagacgactc agatgcacgg
     1501 acacccagat gacatggatg cacggacgac tcagatccac agatgactca aacgcacaga
     1561 tgactgggat gctcagatga ccgctgctgt gctgccaccc cagggctctc tgggcgtttc
     1621 ctgtggtttg ggcaccagga gcctgggagt cccatgctgc ccccagggca ctacctcctg
     1681 ggcccagccc tgcatccggt ggcagggctc accgtcatca ccccaacagt gcagggtggt
     1741 ctcagggacc tcctctcatc attgccaa
//
