LOCUS       XM_017001789            3420 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X1, mRNA.
ACCESSION   XM_017001789
VERSION     XM_017001789.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017001789.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3420
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..3420
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 34 ESTs, 49 long SRA reads, 2 Proteins, and 96%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 13 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             221..2032
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X1"
                     /protein_id="XP_016857278.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MPSRTGPKMEGSGGRVRLKAHYGGDIFITSVDAATTFEELCEEV
                     RDMCRLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLARQCRDEGLIIHVFPSTPEQ
                     PGLPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYR
                     CINCKLLVHKRCHGLVPLTCRKHMDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSS
                     RKHDSIKDDSEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQ
                     IYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLRRLSPCRL
                     FLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLL
                     DADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMF
                     EMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKER
                     LGCRPQTGFSDIKSHAFFRSIDWDLMHRQLRCTDARTTWTPRRCGRTDDMDAQTMWMH
                     GRRRHTDDSSTDDSDARTPRRRGRTDDADAQMTWTHR"
ORIGIN      
        1 gttcggacac cgccccccgc ccccgccgga cggtcccgcc ccgcgcgccc cccgctcccg
       61 ccccgcgcgc cgccggagtt ccgcggagtt gaccgggtcg gcgccgtcgg tcctgagcgc
      121 tgccttccgc gttccgccgc ggccccacct ggagcccccg ccccgcgcca tggccggagc
      181 tcccggggcg cagcgctgac ggcggcgggg ggagcgcgcc atgcccagca ggaccggccc
      241 caagatggaa gggagcggcg gccgcgtccg cctcaaggcg cattacgggg gggacatctt
      301 catcaccagc gtggacgccg ccacgacctt cgaggagctc tgtgaggaag tgagagacat
      361 gtgtcgtctg caccagcagc acccgctcac cctcaagtgg gtggacagcg aaggtgaccc
      421 ttgcacggtg tcctcccaga tggagctgga agaggctttc cgcctggccc gtcagtgcag
      481 ggatgaaggc ctcatcattc atgttttccc gagcacccct gagcagcctg gcctgccatg
      541 tccgggagaa gacaaatcta tctaccgccg gggagccaga agatggagga agctgtaccg
      601 tgccaacggc cacctcttcc aagccaagcg ctttaacagg agagcgtact gcggtcagtg
      661 cagcgagagg atatggggcc tcgcgaggca aggctacagg tgcatcaact gcaaactgct
      721 ggtccataag cgctgccacg gcctcgtccc gctgacctgc aggaagcata tggattctgt
      781 catgccttcc caagagcctc cagtagacga caagaacgag gacgccgacc ttccttccga
      841 ggagacagat ggaattgctt acatttcctc atcccggaag catgacagca ttaaagacga
      901 ctcggaggac cttaagccag ttatcgatgg gatggatgga atcaaaatct ctcaggggct
      961 tgggctgcag gactttgacc taatcagagt catcgggcgc gggagctacg ccaaggttct
     1021 cctggtgcgg ttgaagaaga atgaccaaat ttacgccatg aaagtggtga agaaagagct
     1081 ggtgcatgat gacgaggata ttgactgggt acagacagag aagcacgtgt ttgagcaggc
     1141 atccagcaac cccttcctgg tcggattaca ctcctgcttc cagacgacaa gtcgcctccg
     1201 gcgcctctct ccctgcaggt tgttcctggt cattgagtac gtcaacggcg gggacctgat
     1261 gttccacatg cagaggcaga ggaagctccc tgaggagcac gccaggttct acgcggccga
     1321 gatctgcatc gccctcaact tcctgcacga gagggggatc atctacaggg acctgaagct
     1381 ggacaacgtc ctcctggatg cggacgggca catcaagctc acagactacg gcatgtgcaa
     1441 ggaaggcctg ggccctggtg acacaacgag cactttctgc ggaaccccga attacatcgc
     1501 ccccgaaatc ctgcggggag aggagtacgg gttcagcgtg gactggtggg cgctgggagt
     1561 cctcatgttt gagatgatgg ccgggcgctc cccgttcgac atcatcaccg acaacccgga
     1621 catgaacaca gaggactacc ttttccaagt gatcctggag aagcccatcc ggatcccccg
     1681 gttcctgtcc gtcaaagcct cccatgtttt aaaaggattt ttaaataagg accccaaaga
     1741 gaggctcggc tgccggccac agactggatt ttctgacatc aagtcccacg cgttcttccg
     1801 cagcatagac tgggacttga tgcacagaca actcagatgc acagacgccc ggacgacgtg
     1861 gacacccaga cgatgtggac gcacagacga catggacgca cagacgatgt ggatgcacgg
     1921 acgacgtaga cacacggatg actcatccac agatgactca gatgcacgga cacccagacg
     1981 acgcggacgc acagacgacg cggacgcaca gatgacgtgg acgcacagat gacgtggacg
     2041 cacggacgac gtggatgcat ggacgacgtg gacgcacaga tgacctggac gcacggacga
     2101 cgtggacgca cggatgactc agatccccag acgactcaga tgcacggaca cccagatgac
     2161 atggatgcac ggacgactca gatccacaga tgactcaaac gcacagatga ctgggatgct
     2221 cagatgaccg ctgctgtgct gccaccccag ggctctctgg gcgtttcctg tggtttgggc
     2281 accaggagcc tgggagtccc atgctgcccc cagggcacta cctcctgggc ccagccctgc
     2341 atccggtggc agggctcacc gtcatcaccc caacagtgca gggtggtctc agggacctcc
     2401 tctcatcatt gccaagaact ggctccagga tgtttccatg tggccggcta gtatggccaa
     2461 agtggaccct ggcgtgctgt ccccttggac gcctccaggc cctgcccagc acgtggggct
     2521 cgtccattct gtgcctgacc atgctctgcc atgcggggcc tagcccagcc ccccagccct
     2581 gctgcttctc cccaccccac ccccgccacc tccaccaagc caccagcatc ctgcctggcc
     2641 ctacggacag cagggtcgtc ctgtgtccaa aagcctcctc cccctcagcc ccttcactcg
     2701 ggtctcatgg ggcccctctg tggcccccag cgcacaaggc acacacccac tatggggcct
     2761 ttgcacagct gtgccctccc caggctccag ccctcacctc ccccaggcta tttctcagat
     2821 gtcccttcag aactagagcc cttgggcccc cagccccatt gacacggaac gggccccctg
     2881 ttgtatctca ggtcactgct gtggttgcag ccacaggggc aacacctgtt actgccacag
     2941 cgtccgacct ggggccagcg tgcattcaaa cgcactgctc tgagaggcca ggacgtccat
     3001 gggttgggcg cagggggcgg cggtgggaaa aggtgtcagg caccatgggt cccgacctgg
     3061 agcccacgtg ccagctgcag agatgggcac tgaaggcttt tgagcaagag gaggaggtaa
     3121 cgctggcccc tggggatgct gtcagggaaa ctgaggcaat cttgagccct cggagcagag
     3181 aacgggctgg gccaggggct ggaggaccct gggccagctc cagctgggtc ctgctctgtt
     3241 cccacccctg ctgcttatta aacccttgta aagcagcaca ggactaaggt agggaaagta
     3301 ctttaggaaa tgcccctttt tcacatttta tcggcaggtg tttcatacaa agaatacaag
     3361 taactgatga atgaaggggg catcttgtgt ccccacaatc ctgctgtgcg cacaccacag
//
