LOCUS       XM_011541776            2103 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C zeta (PRKCZ), transcript
            variant X20, mRNA.
ACCESSION   XM_011541776
VERSION     XM_011541776.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011541776.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2103
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..2103
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /note="protein kinase C zeta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 30
                     ESTs, 220 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 5 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
     CDS             482..1720
                     /gene="PRKCZ"
                     /gene_synonym="PKC-ZETA; PKC2"
                     /codon_start=1
                     /product="protein kinase C zeta type isoform X14"
                     /protein_id="XP_011540078.1"
                     /db_xref="GeneID:5590"
                     /db_xref="HGNC:HGNC:9412"
                     /db_xref="MIM:176982"
                     /translation="MDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDD
                     SEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKK
                     ELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQ
                     RQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEG
                     LGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPD
                     MNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAF
                     FRSIDWDLMHRQLRCTDARTTWTPRRCGRTDDMDAQTMWMHGRRRHTDDSSTDDSDAR
                     TPRRRGRTDDADAQMTWTHR"
ORIGIN      
        1 agctgctggc tacagcttcc cgggggagcc gggtaccacc cgggcctgga gacatgagga
       61 ggcagggatg tgaggggcgg gggacaggac agccggcctt ccgttaaata tctgctcctc
      121 gcgctcgagc ctccctgcct attgtcgggg ccggaggcga gccgacgcag catcagctcg
      181 tcaacgggaa ggaagatgcc tccctgcacg cccgccgcgc acagagcata aagaatctgc
      241 gctgaggagg caggagaaga aagccgaatc tatctaccgc cggggagcca gaagatggag
      301 gaagctgtac cgtgccaacg gccacctctt ccaagccaag cgctttaaca ggagagcgta
      361 ctgcggtcag tgcagcgaga ggatatgggg cctcgcgagg caaggctaca ggtgcatcaa
      421 ctgcaaactg ctggtccata agcgctgcca cggcctcgtc ccgctgacct gcaggaagca
      481 tatggattct gtcatgcctt cccaagagcc tccagtagac gacaagaacg aggacgccga
      541 ccttccttcc gaggagacag atggaattgc ttacatttcc tcatcccgga agcatgacag
      601 cattaaagac gactcggagg accttaagcc agttatcgat gggatggatg gaatcaaaat
      661 ctctcagggg cttgggctgc aggactttga cctaatcaga gtcatcgggc gcgggagcta
      721 cgccaaggtt ctcctggtgc ggttgaagaa gaatgaccaa atttacgcca tgaaagtggt
      781 gaagaaagag ctggtgcatg atgacgagga tattgactgg gtacagacag agaagcacgt
      841 gtttgagcag gcatccagca accccttcct ggtcggatta cactcctgct tccagacgac
      901 aagtcggttg ttcctggtca ttgagtacgt caacggcggg gacctgatgt tccacatgca
      961 gaggcagagg aagctccctg aggagcacgc caggttctac gcggccgaga tctgcatcgc
     1021 cctcaacttc ctgcacgaga gggggatcat ctacagggac ctgaagctgg acaacgtcct
     1081 cctggatgcg gacgggcaca tcaagctcac agactacggc atgtgcaagg aaggcctggg
     1141 ccctggtgac acaacgagca ctttctgcgg aaccccgaat tacatcgccc ccgaaatcct
     1201 gcggggagag gagtacgggt tcagcgtgga ctggtgggcg ctgggagtcc tcatgtttga
     1261 gatgatggcc gggcgctccc cgttcgacat catcaccgac aacccggaca tgaacacaga
     1321 ggactacctt ttccaagtga tcctggagaa gcccatccgg atcccccggt tcctgtccgt
     1381 caaagcctcc catgttttaa aaggattttt aaataaggac cccaaagaga ggctcggctg
     1441 ccggccacag actggatttt ctgacatcaa gtcccacgcg ttcttccgca gcatagactg
     1501 ggacttgatg cacagacaac tcagatgcac agacgcccgg acgacgtgga cacccagacg
     1561 atgtggacgc acagacgaca tggacgcaca gacgatgtgg atgcacggac gacgtagaca
     1621 cacggatgac tcatccacag atgactcaga tgcacggaca cccagacgac gcggacgcac
     1681 agacgacgcg gacgcacaga tgacgtggac gcacagatga cgtggacgca cggacgacgt
     1741 ggatgcatgg acgacgtgga cgcacagatg acctggacgc acggacgacg tggacgcacg
     1801 gatgactcag atccccagac gactcagatg cacggacacc cagatgacat ggatgcacgg
     1861 acgactcaga tccacagatg actcaaacgc acagatgact gggatgctca gatgaccgct
     1921 gctgtgctgc caccccaggg ctctctgggc gtttcctgtg gtttgggcac caggagcctg
     1981 ggagtcccat gctgccccca gggcactacc tcctgggccc agccctgcat ccggtggcag
     2041 ggctcaccgt catcacccca acagtgcagg gtggtctcag ggacctcctc tcatcattgc
     2101 caa
//
