LOCUS       XM_047448575            4585 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C iota (PRKCI), transcript
            variant X2, mRNA.
ACCESSION   XM_047448575
VERSION     XM_047448575.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4585
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..4585
                     /gene="PRKCI"
                     /gene_synonym="DXS1179E; nPKC-iota; PKCI"
                     /note="protein kinase C iota; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 20 ESTs, 1209 long SRA reads, 6 Proteins, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 70 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5584"
                     /db_xref="HGNC:HGNC:9404"
                     /db_xref="MIM:600539"
     CDS             287..1735
                     /gene="PRKCI"
                     /gene_synonym="DXS1179E; nPKC-iota; PKCI"
                     /codon_start=1
                     /product="protein kinase C iota type isoform X2"
                     /protein_id="XP_047304531.1"
                     /db_xref="GeneID:5584"
                     /db_xref="HGNC:HGNC:9404"
                     /db_xref="MIM:600539"
                     /translation="MPCPGEDKSIYRRGARRWRKLYCANGHTFQAKRFNRRAHCAICT
                     DRIWGLGRQGYKCINCKLLVHKKCHKLVTIECGRHSLPQEPVMPMDQSSMHSDHAQTV
                     IPYNPSSHESLDQVGEEKEAMNTRESGKASSSLGLQDFDLLRVIGRGSYAKVLLVRLK
                     KTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLHSCFQTESRLFFVI
                     EYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEG
                     HIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMA
                     GRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLG
                     CHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDNFDSQFTNEPVQLT
                     PDDDDIVRKIDQSEFEGFEYINPLLMSAEECV"
ORIGIN      
        1 caagtgcaac tgttcttcag tacttttgta gcttttcatt tctgtgactc ctttgaggag
       61 gctctgtcat gtgaaaggaa aaatttgata aaatgattac atggagactt ctaactaatc
      121 gtattgtggc aatggaacta ctttcacttc ctcttttaaa gaaacaggag acccgtgtac
      181 agtatcatct cagttggagt tagaagaagc ctttagactt tatgagctaa acaaggattc
      241 tgaactcttg attcatgtgt tcccttgtgt accagaacgt cctgggatgc cttgtccagg
      301 agaagataaa tccatctacc gtagaggtgc acgccgctgg agaaagcttt attgtgccaa
      361 tggccacact ttccaagcca agcgtttcaa caggcgtgct cactgtgcca tctgcacaga
      421 ccgaatatgg ggacttggac gccaaggata taagtgcatc aactgcaaac tcttggttca
      481 taagaagtgc cataaactcg tcacaattga atgtgggcgg cattctttgc cacaggaacc
      541 agtgatgccc atggatcagt catccatgca ttctgaccat gcacagacag taattccata
      601 taatccttca agtcatgaga gtttggatca agttggtgaa gaaaaagagg caatgaacac
      661 cagggaaagt ggcaaagctt catccagtct aggtcttcag gattttgatt tgctccgggt
      721 aataggaaga ggaagttatg ccaaagtact gttggttcga ttaaaaaaaa cagatcgtat
      781 ttatgcaatg aaagttgtga aaaaagagct tgttaatgat gatgaggata ttgattgggt
      841 acagacagag aagcatgtgt ttgagcaggc atccaatcat cctttccttg ttgggctgca
      901 ttcttgcttt cagacagaaa gcagattgtt ctttgttata gagtatgtaa atggaggaga
      961 cctaatgttt catatgcagc gacaaagaaa acttcctgaa gaacatgcca gattttactc
     1021 tgcagaaatc agtctagcat taaattatct tcatgagcga gggataattt atagagattt
     1081 gaaactggac aatgtattac tggactctga aggccacatt aaactcactg actacggcat
     1141 gtgtaaggaa ggattacggc caggagatac aaccagcact ttctgtggta ctcctaatta
     1201 cattgctcct gaaattttaa gaggagaaga ttatggtttc agtgttgact ggtgggctct
     1261 tggagtgctc atgtttgaga tgatggcagg aaggtctcca tttgatattg ttgggagctc
     1321 cgataaccct gaccagaaca cagaggatta tctcttccaa gttattttgg aaaaacaaat
     1381 tcgcatacca cgttctctgt ctgtaaaagc tgcaagtgtt ctgaagagtt ttcttaataa
     1441 ggaccctaag gaacgattgg gttgtcatcc tcaaacagga tttgctgata ttcagggaca
     1501 cccgttcttc cgaaatgttg attgggatat gatggagcaa aaacaggtgg tacctccctt
     1561 taaaccaaat atttctgggg aatttggttt ggacaacttt gattctcagt ttactaatga
     1621 acctgtccag ctcactccag atgacgatga cattgtgagg aagattgatc agtctgaatt
     1681 tgaaggtttt gagtatatca atcctctttt gatgtctgca gaagaatgtg tctgatcctc
     1741 atttttcaac catgtattct actcatgttg ccatttaatg catggataaa cttgctgcaa
     1801 gcctggatac aattaaccat tttatatttg ccacctacaa aaaaacaccc aatatcttct
     1861 cttgtagact atatgaatca attattacat ctgttttact atgaaaaaaa aattaatact
     1921 actagcttcc agacaatcat gtcaaaattt agttgaactg gtttttcagt ttttaaaagg
     1981 cctacagatg agtaatgaag ttatcttttt tgtttaaaaa aaaaaaaaac actgcattaa
     2041 aaaagtatct gttgcattaa ggcacatagt gggattacat cataaacctc ccataatttt
     2101 tgtcattctg tgttaaatca tttcagggtt taattttgaa ataaaagatt aatataaaat
     2161 gcaacaactt tttatattac ctattagttt tggagttctt tatgtttaaa aattcaggtg
     2221 taaattttat tgccttggat aaataaatta ttgatctttt ttaaggcagc agttattaaa
     2281 ttggtaatag aagatgctgc ttgcttagaa ttgggaaatt cggctgggtg cagtgactca
     2341 atgcctgtga tcccagtact ttgggaggtt gaggcgggca gatcacttga ggtcaggagt
     2401 ttgagattgg cctggtcaac atggtgaaat cctgtctcta ctaaaaatac aaaaattagc
     2461 tgggcatggt ggcacatacc tgtaatccca gctactcggg aggctgaaac aggagaatcg
     2521 cttgaaccca ggagatggag ttggcagtga gccaagatta gcctgggcaa cagtgagtga
     2581 gactcggtct caaacaaaaa ccaaattggg aaattcttct tgagttaaaa aagacacttt
     2641 ttattatgaa tcagattcca aatcattaac tatttttgca aaactggcac aagtggtttt
     2701 tctttttaag tatattaaca gggtagctcc tgagcctttc cctttattgg aaactttaac
     2761 tgcagtgtta atatatacac tgcaaaagac caaggatgca gttgaatgga aaattactca
     2821 gtgtatagaa aggaaaaaaa ccagaaattt aaaatagata cagaaaagta cactggtaat
     2881 atttttattt cctattggag agtgaatccc cacagttgct ttttgtgact tgattcaaat
     2941 gaggcactca ttattgttac caaacttgta aaagcattcc atgtattcag tggaggcaga
     3001 atgtataata ttttttcctt ataatttagc atacaggaaa agtatttatt ttttaagtag
     3061 ggtatcttaa ttatgctcat ttcttcccct aaaccacatt atctatatga ttggaccctt
     3121 tagtgaaatc agaaaaataa agtaggcatg aataaatgtt caggacacac acatacactc
     3181 acacacatca cagtatcagc tctttcagtg agtttttatt aactagataa cacatgtaat
     3241 acatagtaga atacatttca gaggcagagt tcctcggatt attttttatg gatattagtg
     3301 ttcagcagct tattatttaa aggggtgcca aatatagcat ccttctgttg tttattttaa
     3361 atatattttt aatgaaaagg gacttaaaaa gtaaacatga ttatctaaat tacttaaaat
     3421 tttttaatct tagtaaaaat tttaggaaag ttatctagtt taaatttcaa atgttttaaa
     3481 atttgtaggc atttaataaa ttatcttttt ttggaggggt ggatgctgca tttcattgga
     3541 aatgtcattt ttccaaagtt tctagctata tactctcttt ccttcaaata acataagtct
     3601 gaaagcaatg aaaacgtcaa aggaaaatgt ttatatacat ccacatgttt atttaatatg
     3661 tttctcttaa cacctgaaac ttgttttaaa acaaaaagca gtattcactt caaatcataa
     3721 acttagaatt ctgtatctca tgtcagaaat atgtttatgg ccttgctttt aagtggtgct
     3781 gtttcccata gggcattagt tctcagattt tggaatgtga aataatcacc taggaagttg
     3841 gtttaaaatg cacactagtg agcccacctt agacttcttt tggggccttc gacctcactt
     3901 tgagaaatac cttcttcagg ttattcttta tgtttgtcct gtggttaaat attagagtat
     3961 tcatgataaa acattttgag aaggggtaag cagtgagtta ttacccacaa tttaaagcaa
     4021 attttgaatg aatctttaag ttaggtatct accttcccac cagcccccca aaaaacctct
     4081 cagtagtttc tttcagtgta caaaatgatg agcatttttc tatgatgagg ttttaaccat
     4141 tattcagggt ggtcttttgt ttttaaatct ttttttaact aataagattt acggtgtgta
     4201 ttttatacag aaatgcatta taaatgtttt taattgtgtt ctgttttttg cagtctttaa
     4261 gtgccatgcc aattgttctt atattctata gaagttcgct caaaatactc aacaggggaa
     4321 taggcagcgg acagtcagaa tggttggaat tttggctttc taagaaaaac tttattttgc
     4381 ataagcatgt ggtcagatca ttttgtgcat atgcagcctg gattggatgt taagtaaatg
     4441 cttgttcagt gccggtacat ttacttaaat ctgtttttat ttttgtcatg tagaatacta
     4501 ctgtggtcat cataatgtaa tctatttctg tacctttttt tttttttttt actttgaagt
     4561 ctttaaataa aatgtataat accca
//
