LOCUS       XM_011536957            2008 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C eta (PRKCH), transcript
            variant X7, mRNA.
ACCESSION   XM_011536957
VERSION     XM_011536957.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011536957.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2008
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..2008
                     /gene="PRKCH"
                     /gene_synonym="nPKC-eta; PKC-L; PKCL; PRKCL; uORF2"
                     /note="protein kinase C eta; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 35
                     ESTs, 121 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     12 samples with support for all annotated introns"
                     /db_xref="GeneID:5583"
                     /db_xref="HGNC:HGNC:9403"
                     /db_xref="MIM:605437"
     CDS             524..1993
                     /gene="PRKCH"
                     /gene_synonym="nPKC-eta; PKC-L; PKCL; PRKCL; uORF2"
                     /codon_start=1
                     /product="protein kinase C eta type isoform X6"
                     /protein_id="XP_011535259.1"
                     /db_xref="GeneID:5583"
                     /db_xref="HGNC:HGNC:9403"
                     /db_xref="MIM:605437"
                     /translation="MSSGTMKFNGYLRVRIGEAVGLQPTRWSLRHSLFKKGHQLLDPY
                     LTVSVDQVRVGQTSTKQKTNKPTYNEEFCANVTDGGHLELAVFHETPLGYDHFVANCT
                     LQFQELLRTTGASDTFEGWVDLEPEGKVFVVITLTGSFTEATLQRDRIFKHFTRKRQR
                     AMRRRVHQINGHKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLI
                     VTACTCQNNINKVDSKIAEQRFGINIPHKFSIHNYKVPTFCDHCGSLLWGIMRQGLQC
                     KICKMNVHIRCQANVAPNCGVNAVELAKTLAGMGLQPGNISPTSKLVSRSTLRRQGKE
                     SSKEGNGIGVNSSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVIL
                     QDDDVECTMTEKRILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRR
                     FDEARARFYAAEIISALMFLHDKGIIYRTAYIFLWSAHS"
ORIGIN      
        1 gtgaacttgg aacctggcgg tgcgaggttc tcgccgggga tgcggcggcg gcagctgctt
       61 cctggtttga agctcgccga gtgggggaga gcgtgagcct tcggaggcgg gggcaggagg
      121 agaagcaaga ggaggcgggg gaagagacgc ttggggctgg ggctcaccgg acgggtaggt
      181 ccggctctcc agggagagga gctgcccggc cctggagaag gggcgagtcc tgcgcgagtc
      241 cccgggaggc gccgcgcgct tggaagggac ggtcgggctt ccccggcccg ctgagggctc
      301 ggcggcgggc tcccctcctt tccacctcgg gagggaggga aggaggggag ggaaaagtcc
      361 cacggaggag gcagaatggc cagtcgaggg gcgcttaggc gctgcctttc cccagggctg
      421 cctcgactcc tgcacctgtc ccgagggctg gcctgagacg ggactcccgg ttctcccgct
      481 gcgaagcagc gcggcccccc ggggccgggg cagcggcgcc ggcatgtcgt ctggcaccat
      541 gaagttcaat ggctatttga gggtccgcat cggtgaggca gtggggctgc agcccacccg
      601 ctggtccctg cgccactcgc tcttcaagaa gggccaccag ctgctggacc cctatctgac
      661 ggtgagcgtg gaccaggtgc gcgtgggcca gaccagcacc aagcagaaga ccaacaaacc
      721 cacgtacaac gaggagtttt gcgctaacgt caccgacggc ggccacctcg agttggccgt
      781 cttccacgag acgcccctgg gctacgacca cttcgtggcc aactgcaccc tgcagttcca
      841 ggagctgctg cgcacgaccg gcgcctcgga caccttcgag ggttgggtgg atctcgagcc
      901 agaggggaaa gtatttgtgg taataaccct taccgggagt ttcactgaag ctactctcca
      961 gagagaccgg atcttcaaac attttaccag gaagcgccaa agggctatgc gaaggcgagt
     1021 ccaccagatc aatggacaca agttcatggc cacgtatctg aggcagccca cctactgctc
     1081 tcactgcagg gagtttatct ggggagtgtt tgggaaacag ggttatcagt gccaagtgtg
     1141 cacctgtgtc gtccataaac gctgccatca tctaattgtt acagcctgta cttgccaaaa
     1201 caatattaac aaagtggatt caaagattgc agaacagagg ttcgggatca acatcccaca
     1261 caagttcagc atccacaact acaaagtgcc aacattctgc gatcactgtg gctcactgct
     1321 ctggggaata atgcgacaag gacttcagtg taaaatatgt aaaatgaatg tgcatattcg
     1381 atgtcaagcg aacgtggccc ctaactgtgg ggtaaatgcg gtggaacttg ccaagaccct
     1441 ggcagggatg ggtctccaac ccggaaatat ttctccaacc tcgaaactcg tttccagatc
     1501 gaccctaaga cgacagggaa aggagagcag caaagaagga aatgggattg gggttaattc
     1561 ttccaaccga cttggtatcg acaactttga gttcatccga gtgttgggga aggggagttt
     1621 tgggaaggtg atgcttgcaa gagtaaaaga aacaggagac ctctatgctg tgaaggtgct
     1681 gaagaaggac gtgattctgc aggatgatga tgtggaatgc accatgaccg agaaaaggat
     1741 cctgtctctg gcccgcaatc accccttcct cactcagttg ttctgctgct ttcagacccc
     1801 cgatcgtctg ttttttgtga tggagtttgt gaatgggggt gacttgatgt tccacattca
     1861 gaagtctcgt cgttttgatg aagcacgagc tcgcttctat gctgcagaaa tcatttcggc
     1921 tctcatgttc ctccatgata aaggaatcat ctataggaca gcctacattt tcctgtggtc
     1981 agcccattct taatgggcgc atcatctt
//
