LOCUS       XM_047445099            6889 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C epsilon (PRKCE),
            transcript variant X9, mRNA.
ACCESSION   XM_047445099
VERSION     XM_047445099.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6889
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6889
                     /gene="PRKCE"
                     /gene_synonym="nPKC-epsilon; PKCE"
                     /note="protein kinase C epsilon; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 21 ESTs, 680 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 2 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5581"
                     /db_xref="HGNC:HGNC:9401"
                     /db_xref="MIM:176975"
     CDS             1909..3780
                     /gene="PRKCE"
                     /gene_synonym="nPKC-epsilon; PKCE"
                     /codon_start=1
                     /product="protein kinase C epsilon type isoform X3"
                     /protein_id="XP_047301055.1"
                     /db_xref="GeneID:5581"
                     /db_xref="HGNC:HGNC:9401"
                     /db_xref="MIM:176975"
                     /translation="MQIDLEPEGRVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQG
                     AVRRRVHQVNGHKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELI
                     ITKCAGLKKQETPDQVGSQRFSVNMPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCK
                     VCKMNVHRRCETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQP
                     ASGSSPSEEDRSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPG
                     ENGEVRQGQAKRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDD
                     DVDCTMTEKRILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDE
                     PRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTT
                     TTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHD
                     DVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKK
                     IKPPFKPRIKTKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP"
ORIGIN      
        1 attttcaatt tccaagcagc taagattcta gtggacgtca gtttgtgctg gctttatttt
       61 cacaaatgct ccattgggtg ccacatgcga atgtggctgt tggccgcagg ttaggtggca
      121 cacgctcatt ttgtgggcaa gttctggaaa agtggttagc atagggtttt gcaacgtagt
      181 gatctacttt atagatttat atgtaagtac ccagattggt ggtaggtgaa tttggtggaa
      241 tcattttcta ccagcatcct aaaatcatat ttagaattgt attttagcaa aatgaatgta
      301 gtctggctgg atataaaaca aaaatttcca gttgggggtg aaagtgaagg gaagggctat
      361 ttagagggag tgtccccagc cggtggggac ctggctccct gggggttgtg gatgggggta
      421 taagaggctc gattttgccc atctctgcta atgatgtgga gctccagtaa acagcaagtt
      481 aatggacttc ccagatatgt gaatttcaac agctgttgca aacaacagtg agcacagaaa
      541 aaaaaatata tgaaggaaga gagaaaggaa gaggaaagag aggaagagag ggggaggggt
      601 gtcagcaatg gaagtaggaa acaacaagga tgaggtccag tttttaaaat ccagattctt
      661 gtatctgggc ctgattgcaa atgccatgta tcctaggaag ccatctggaa aaacagccaa
      721 tctgagaatg ccctgagggt ggccaaggac agacttgtgg agggagttgt ctggatttcc
      781 tagggcttgg tgtgccttta gaggggagta gaacagactt ttgatataga aagtacatgt
      841 ggttaccctc ccttttggga gaattaacat ccatggactt agaaattcac catcagtagt
      901 aggttaaaat ttatgtattg ccaaggagtg gtaagagatt acatcttgtc atcttgtttt
      961 aagactcttt ataaactagc ccctagtttt tattttttct agcttcgtct atttctattt
     1021 ttaatagacg ccttatacct caggcaggtg gggtggtttg ctgttcccat aatatatttt
     1081 tttccttctg cttggaagct ctgccttgtg cccccaactc cctcctgtcc tcctccctgt
     1141 ctgctgttcg tccttagcag gcaaaggagg ggctccccct aatccccaga ggtgtcactc
     1201 cctgcagggc ccagcagcct tttgcacgga cctctgctgg gacactgacc ccactgcctt
     1261 cttgttatgt gtgtctttgt ctgtagcttc tcagagttaa gatgctgaaa tattgcagtg
     1321 aagtaggcct ttttctttct ctgtctctca agtgactcaa attgtttcgc tgacttgatc
     1381 agagctcagt aaaggttggc tgagtcagag tgaatgagtt aaccatgagt tacaaagtga
     1441 aggaatagcc agattgcttc ctctgtgaca ccacacagag cccgtctgtg tggttgaggg
     1501 gccgctggtg aaggatgagg ggcaccagcc cccatgctgt gtgggtcact gtagacatgg
     1561 ctctgctgtc atctgtacag aggccaaact tgttttagcc ttaataactg tttaaagctg
     1621 actcccaagg aaaccagtct tgttttttta tggtcctgga ggatttcaga agcagatctg
     1681 gagatgtgtg tgcacaggat attcaagtct gtgcttctgc ttgactgagg atcatctagg
     1741 aaatgaaact aaacttggct tcgacctaga ccttgtgtga ccttgaggtc atcaccctct
     1801 cacagtcacc ctagagaatc ctttacttac ctgtgctgaa aaaaatgctc ccatcagtta
     1861 ccctatgatg aggtctccag ccctttcatc agaagacaga gctttaaaat gcagattgat
     1921 ctggagccag aaggaagagt gtatgtgatc atcgatctct cagggtcgtc gggtgaagcc
     1981 cctaaagaca atgaagagcg tgtgttcagg gaacgcatgc ggccgaggaa gcggcagggg
     2041 gccgtcaggc gcagggtcca tcaggtcaac ggccacaagt tcatggccac ctatcttcgg
     2101 cagcccacct actgctccca ttgcagagac ttcatctggg gtgtcatagg aaagcaggga
     2161 taccagtgtc aagtctgcac ctgcgtggtc cacaagcggt gccacgagct cataatcaca
     2221 aagtgtgctg ggttaaagaa gcaggagacc cccgaccagg tgggctccca gcggttcagc
     2281 gtcaacatgc cccacaagtt cggtatccac aactacaagg tccctacctt ctgcgatcac
     2341 tgtgggtccc tgctctgggg actcttgcgg cagggtttgc agtgtaaagt ctgcaaaatg
     2401 aatgttcacc gtcgatgtga gaccaacgtg gctcccaact gtggagtgga tgccagagga
     2461 atcgccaaag tactggccga cctgggcgtt accccagaca aaatcaccaa cagcggccag
     2521 agaaggaaaa agctcattgc tggtgccgag tccccgcagc ctgcttctgg aagctcacca
     2581 tctgaggaag atcgatccaa gtcagcaccc acctcccctt gtgaccagga aataaaagaa
     2641 cttgagaaca acattcggaa agccttgtca tttgacaacc gaggagagga gcaccgggca
     2701 gcatcgtctc ctgatggcca gctgatgagc cccggtgaga atggcgaagt ccggcaaggc
     2761 caggccaagc gcctgggcct ggatgagttc aacttcatca aggtgttggg caaaggcagc
     2821 tttggcaagg tcatgttggc agaactcaag ggcaaagatg aagtatatgc tgtgaaggtc
     2881 ttaaagaagg acgtcatcct tcaggatgat gacgtggact gcacaatgac agagaagagg
     2941 attttggctc tggcacggaa acacccgtac cttacccaac tctactgctg cttccagacc
     3001 aaggaccgcc tctttttcgt catggaatat gtaaatggtg gagacctcat gtttcagatt
     3061 cagcgctccc gaaaattcga cgagcctcgt tcacggttct atgctgcaga ggtcacatcg
     3121 gccctcatgt tcctccacca gcatggagtc atctacaggg atttgaaact ggacaacatc
     3181 cttctggatg cagaaggtca ctgcaagctg gctgacttcg ggatgtgcaa ggaagggatt
     3241 ctgaatggtg tgacgaccac cacgttctgt gggactcctg actacatagc tcctgagatc
     3301 ctgcaggagt tggagtatgg cccctccgtg gactggtggg ccctgggggt gctgatgtac
     3361 gagatgatgg ctggacagcc tccctttgag gccgacaatg aggacgacct atttgagtcc
     3421 atcctccatg acgacgtgct gtacccagtc tggctcagca aggaggctgt cagcatcttg
     3481 aaagctttca tgacgaagaa tccccacaag cgcctgggct gtgtggcatc gcagaatggc
     3541 gaggacgcca tcaagcagca cccattcttc aaagagattg actgggtgct cctggagcag
     3601 aagaagatca agccaccctt caaaccacgc attaaaacca aaagagacgt caataatttt
     3661 gaccaagact ttacccggga agagccggta ctcacccttg tggacgaagc aattgtaaag
     3721 cagatcaacc aggaggaatt caaaggtttc tcctactttg gtgaagacct gatgccctga
     3781 gagcccactg cagttggact ttgccgatgc tgcaagaagg ggtgcagaga agactcctgt
     3841 gttggagaca ctcagcaggt cttgaactac ttctcctcct cggagcccca gtcccatgtc
     3901 cactgtctat ttattgcatt cccttgcccc aggccacctc ctccccctcc cacctggtga
     3961 ccagaaggcg ctctcggttc ttgtctcacc agtaatgcag actcattggg tcagcaatta
     4021 gctgtataca ctgccgtgtt tggaccattg gcaagcctgg ttccactcct caggggctcc
     4081 tggcagtgaa gcaacttcag ttcttttact gcaaagaaca gaaaaaagaa agaaagcaaa
     4141 caagaagact ccggctctgc tatcggacac agatcctgat ccctcttgct tcttttccct
     4201 cctgcaccgc agcttgccat ccctgccctt ctgtcctgga gaagagactg gtgcttctcc
     4261 gcacacacga gggagggcgc ccttgaggca tgccctctga gggagggaga ccagagatgc
     4321 agggattggc cagctgggtt ggtttgctct ggaatggcta actcttgcct gctttggttt
     4381 tagcttttca gcatgccaaa gtcatgtaag tttgtgtctt gtggaagaaa tcctctttgt
     4441 ggaaaaagaa acagggtttt gaactctgtt aacatttgaa aaatatattt tcaaattcac
     4501 tttctaattg gccaaaagag atgagttcca gtctgaatac aggtagatat taaagggcta
     4561 ataaaaaatg agaaaccggt cgtccaaggt ggatgctgtc aatgcccgag tgacacatga
     4621 gagctgtatg aattgagaga aaaggcaaca agtagcattc ttcatcattc aagttctacc
     4681 tggacacaaa ggcgaggacc ctggggttcc aacaaagctc agctcccaga ttctctttcc
     4741 agtttcatcc taagttccta gcataaacac tatttatttt ctgcagcagt gtgttatttt
     4801 tgcgcactta tacaaaatgg tagtactact gtgttgtggt ttttaaacat taaacatgta
     4861 aagttatata cgaaatatct gcttttggaa taagcagaat gaggctaaac atgggttata
     4921 caaagggtat ctggaaactg aagagcaact tgttagaaaa ctgacaatgt cgcaagatgt
     4981 actcagtttt gtttctgtgt gacatgcaat ggcaactcat gtggacacta ttgaagggat
     5041 gtgacattac ctcctgtaga tatgctaaca gtgttattct ttcatttcca agggttctct
     5101 gtggctttgt gtatatgttt cccagaggtc atttgattac ctaatttact gaactgattt
     5161 agcagggaat ggaatccatt ccaactattg cacgtggatt tcccagctgc ccctaaatat
     5221 atatacttgt gagtggcaaa gtggcactaa tgaagctttt gccttttgta catttgagat
     5281 ttttgtatat agtgtttgct gcaaggcctg tggaattaat tcgttgcata tagaggtatc
     5341 aactgctgca tgttcaggca tattataaaa ctttagtcta tgaaagaata attataataa
     5401 tgtccaggtg caatactctg taagtctatt ggttcaagtt accgagagat aggtgtgttc
     5461 ctttatgggg gatggggggg tgtgttgggg attctttgta ttgtttattt cattttggtt
     5521 tattttaaaa gatgtaaaca tatattaagc tatattaaat ctcacataca gttcttctgt
     5581 gctctattat accctgatag agatggggga gagaaaggaa tgtttttgat ggtggtttca
     5641 aagctcggac agtaactatc ttgagcccat tagagagtct gtgtccatat ttgcatctgg
     5701 ctggtcatag cctttgttac taatgatgac attcagttct cttttgtttt tattttttaa
     5761 aaactcaggt gtaattatta tctgttctta agataattgc aaatattaaa tattatgata
     5821 tatcaattca tgtgtttggc ataccagtga atgatgaaga acatgagatt aatttaattt
     5881 atcttcggta acttgacatt ctggagagag actatcttct ggagttgagt acaagcacag
     5941 aaacatcttt acggtggcat catctcattt tttaggaaga catgataata ctgcccatca
     6001 tattcatgtg taactactgt tctttcttct gctttcttca ccataataaa ctttggacaa
     6061 ccaagcaagc tctaaccgca atgccagatg gccttgtccg agggcctagt gtttgcacgg
     6121 cagtgggaac tgggcctttc ctacaggaca actggcaagt ttgctgggaa gtcaaataat
     6181 acattccacc tggcagctga aggcagccag tcagtctgtc ccagaaaggg cccttttcag
     6241 cacccaaagc tgggctggct gggatgcctc tggctggtga agttctcaca taggctgatt
     6301 taaatccagc aaaggtctat agaaaaaggc ttgcgtgttc gttgagtaat cattgtttca
     6361 ttttcatttt tacgagagtt tgaaaataga cacactgtta acacttctgc cagttttttc
     6421 tgatctttcc agccccaccc cctttctctt tctctctctc tctcaaagaa aaaaaaaatg
     6481 ggagtgcaaa aaaaacaaag ccaaaaaata tatgaaggat agctgttctt ctgtgttctc
     6541 tcattatgga ctttgtgaag tagaaacata attttttttc ctccaaaggt gaaaaaacaa
     6601 tgcattcttg ctttaaaaaa aaaaaagaag gctaaaaaat tacctctttt taaattatgt
     6661 gcaaaataat tctggctaac tgtaaaatgt attcaatttt aggatttttt ttttttgtat
     6721 tgtgatgctt tatttgtaca tttttttcct ttctggatgt aattttaatc tcttgccatt
     6781 cattagtgtt atttcattgt aaacgttatt gtgccaaatg tactgtattc aaaaggatgt
     6841 gaatgtgtat tgtttcagaa cctaataaat acaatgacgt taagtctta
//
