LOCUS       XM_011532983            4523 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C epsilon (PRKCE),
            transcript variant X21, mRNA.
ACCESSION   XM_011532983
VERSION     XM_011532983.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011532983.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4523
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..4523
                     /gene="PRKCE"
                     /gene_synonym="nPKC-epsilon; PKCE"
                     /note="protein kinase C epsilon; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 14 ESTs, 630 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 24 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5581"
                     /db_xref="HGNC:HGNC:9401"
                     /db_xref="MIM:176975"
     CDS             104..1414
                     /gene="PRKCE"
                     /gene_synonym="nPKC-epsilon; PKCE"
                     /codon_start=1
                     /product="protein kinase C epsilon type isoform X9"
                     /protein_id="XP_011531285.1"
                     /db_xref="GeneID:5581"
                     /db_xref="HGNC:HGNC:9401"
                     /db_xref="MIM:176975"
                     /translation="MGCHASCETLSALSWIWKNQQLIAGAESPQPASGSSPSEEDRSK
                     SAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQAKRL
                     GLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILA
                     LARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSA
                     LMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPE
                     ILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAV
                     SILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKR
                     DVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP"
ORIGIN      
        1 agacatggtt tttattcttg tctagaagta aattaagaca gaatctttgt catgaaacat
       61 ttgaaagaaa actcagtacc tgctgtcttt gcgctatatt tacatgggtt gtcatgccag
      121 ctgtgagaca ttgtctgcct tgtcttggat ttggaagaac caacagctca ttgctggtgc
      181 cgagtccccg cagcctgctt ctggaagctc accatctgag gaagatcgat ccaagtcagc
      241 acccacctcc ccttgtgacc aggaaataaa agaacttgag aacaacattc ggaaagcctt
      301 gtcatttgac aaccgaggag aggagcaccg ggcagcatcg tctcctgatg gccagctgat
      361 gagccccggt gagaatggcg aagtccggca aggccaggcc aagcgcctgg gcctggatga
      421 gttcaacttc atcaaggtgt tgggcaaagg cagctttggc aaggtcatgt tggcagaact
      481 caagggcaaa gatgaagtat atgctgtgaa ggtcttaaag aaggacgtca tccttcagga
      541 tgatgacgtg gactgcacaa tgacagagaa gaggattttg gctctggcac ggaaacaccc
      601 gtaccttacc caactctact gctgcttcca gaccaaggac cgcctctttt tcgtcatgga
      661 atatgtaaat ggtggagacc tcatgtttca gattcagcgc tcccgaaaat tcgacgagcc
      721 tcgttcacgg ttctatgctg cagaggtcac atcggccctc atgttcctcc accagcatgg
      781 agtcatctac agggatttga aactggacaa catccttctg gatgcagaag gtcactgcaa
      841 gctggctgac ttcgggatgt gcaaggaagg gattctgaat ggtgtgacga ccaccacgtt
      901 ctgtgggact cctgactaca tagctcctga gatcctgcag gagttggagt atggcccctc
      961 cgtggactgg tgggccctgg gggtgctgat gtacgagatg atggctggac agcctccctt
     1021 tgaggccgac aatgaggacg acctatttga gtccatcctc catgacgacg tgctgtaccc
     1081 agtctggctc agcaaggagg ctgtcagcat cttgaaagct ttcatgacga agaatcccca
     1141 caagcgcctg ggctgtgtgg catcgcagaa tggcgaggac gccatcaagc agcacccatt
     1201 cttcaaagag attgactggg tgctcctgga gcagaagaag atcaagccac ccttcaaacc
     1261 acgcattaaa accaaaagag acgtcaataa ttttgaccaa gactttaccc gggaagagcc
     1321 ggtactcacc cttgtggacg aagcaattgt aaagcagatc aaccaggagg aattcaaagg
     1381 tttctcctac tttggtgaag acctgatgcc ctgagagccc actgcagttg gactttgccg
     1441 atgctgcaag aaggggtgca gagaagactc ctgtgttgga gacactcagc aggtcttgaa
     1501 ctacttctcc tcctcggagc cccagtccca tgtccactgt ctatttattg cattcccttg
     1561 ccccaggcca cctcctcccc ctcccacctg gtgaccagaa ggcgctctcg gttcttgtct
     1621 caccagtaat gcagactcat tgggtcagca attagctgta tacactgccg tgtttggacc
     1681 attggcaagc ctggttccac tcctcagggg ctcctggcag tgaagcaact tcagttcttt
     1741 tactgcaaag aacagaaaaa agaaagaaag caaacaagaa gactccggct ctgctatcgg
     1801 acacagatcc tgatccctct tgcttctttt ccctcctgca ccgcagcttg ccatccctgc
     1861 ccttctgtcc tggagaagag actggtgctt ctccgcacac acgagggagg gcgcccttga
     1921 ggcatgccct ctgagggagg gagaccagag atgcagggat tggccagctg ggttggtttg
     1981 ctctggaatg gctaactctt gcctgctttg gttttagctt ttcagcatgc caaagtcatg
     2041 taagtttgtg tcttgtggaa gaaatcctct ttgtggaaaa agaaacaggg ttttgaactc
     2101 tgttaacatt tgaaaaatat attttcaaat tcactttcta attggccaaa agagatgagt
     2161 tccagtctga atacaggtag atattaaagg gctaataaaa aatgagaaac cggtcgtcca
     2221 aggtggatgc tgtcaatgcc cgagtgacac atgagagctg tatgaattga gagaaaaggc
     2281 aacaagtagc attcttcatc attcaagttc tacctggaca caaaggcgag gaccctgggg
     2341 ttccaacaaa gctcagctcc cagattctct ttccagtttc atcctaagtt cctagcataa
     2401 acactattta ttttctgcag cagtgtgtta tttttgcgca cttatacaaa atggtagtac
     2461 tactgtgttg tggtttttaa acattaaaca tgtaaagtta tatacgaaat atctgctttt
     2521 ggaataagca gaatgaggct aaacatgggt tatacaaagg gtatctggaa actgaagagc
     2581 aacttgttag aaaactgaca atgtcgcaag atgtactcag ttttgtttct gtgtgacatg
     2641 caatggcaac tcatgtggac actattgaag ggatgtgaca ttacctcctg tagatatgct
     2701 aacagtgtta ttctttcatt tccaagggtt ctctgtggct ttgtgtatat gtttcccaga
     2761 ggtcatttga ttacctaatt tactgaactg atttagcagg gaatggaatc cattccaact
     2821 attgcacgtg gatttcccag ctgcccctaa atatatatac ttgtgagtgg caaagtggca
     2881 ctaatgaagc ttttgccttt tgtacatttg agatttttgt atatagtgtt tgctgcaagg
     2941 cctgtggaat taattcgttg catatagagg tatcaactgc tgcatgttca ggcatattat
     3001 aaaactttag tctatgaaag aataattata ataatgtcca ggtgcaatac tctgtaagtc
     3061 tattggttca agttaccgag agataggtgt gttcctttat gggggatggg ggggtgtgtt
     3121 ggggattctt tgtattgttt atttcatttt ggtttatttt aaaagatgta aacatatatt
     3181 aagctatatt aaatctcaca tacagttctt ctgtgctcta ttataccctg atagagatgg
     3241 gggagagaaa ggaatgtttt tgatggtggt ttcaaagctc ggacagtaac tatcttgagc
     3301 ccattagaga gtctgtgtcc atatttgcat ctggctggtc atagcctttg ttactaatga
     3361 tgacattcag ttctcttttg tttttatttt ttaaaaactc aggtgtaatt attatctgtt
     3421 cttaagataa ttgcaaatat taaatattat gatatatcaa ttcatgtgtt tggcatacca
     3481 gtgaatgatg aagaacatga gattaattta atttatcttc ggtaacttga cattctggag
     3541 agagactatc ttctggagtt gagtacaagc acagaaacat ctttacggtg gcatcatctc
     3601 attttttagg aagacatgat aatactgccc atcatattca tgtgtaacta ctgttctttc
     3661 ttctgctttc ttcaccataa taaactttgg acaaccaagc aagctctaac cgcaatgcca
     3721 gatggccttg tccgagggcc tagtgtttgc acggcagtgg gaactgggcc tttcctacag
     3781 gacaactggc aagtttgctg ggaagtcaaa taatacattc cacctggcag ctgaaggcag
     3841 ccagtcagtc tgtcccagaa agggcccttt tcagcaccca aagctgggct ggctgggatg
     3901 cctctggctg gtgaagttct cacataggct gatttaaatc cagcaaaggt ctatagaaaa
     3961 aggcttgcgt gttcgttgag taatcattgt ttcattttca tttttacgag agtttgaaaa
     4021 tagacacact gttaacactt ctgccagttt tttctgatct ttccagcccc accccctttc
     4081 tctttctctc tctctctcaa agaaaaaaaa aatgggagtg caaaaaaaac aaagccaaaa
     4141 aatatatgaa ggatagctgt tcttctgtgt tctctcatta tggactttgt gaagtagaaa
     4201 cataattttt tttcctccaa aggtgaaaaa acaatgcatt cttgctttaa aaaaaaaaaa
     4261 gaaggctaaa aaattacctc tttttaaatt atgtgcaaaa taattctggc taactgtaaa
     4321 atgtattcaa ttttaggatt tttttttttt gtattgtgat gctttatttg tacatttttt
     4381 tcctttctgg atgtaatttt aatctcttgc cattcattag tgttatttca ttgtaaacgt
     4441 tattgtgcca aatgtactgt attcaaaagg atgtgaatgt gtattgtttc agaacctaat
     4501 aaatacaatg acgttaagtc tta
//
