LOCUS       XM_011532982            5319 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase C epsilon (PRKCE),
            transcript variant X15, mRNA.
ACCESSION   XM_011532982
VERSION     XM_011532982.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011532982.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5319
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..5319
                     /gene="PRKCE"
                     /gene_synonym="nPKC-epsilon; PKCE"
                     /note="protein kinase C epsilon; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 23 ESTs, 666 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5581"
                     /db_xref="HGNC:HGNC:9401"
                     /db_xref="MIM:176975"
     CDS             717..2210
                     /gene="PRKCE"
                     /gene_synonym="nPKC-epsilon; PKCE"
                     /codon_start=1
                     /product="protein kinase C epsilon type isoform X5"
                     /protein_id="XP_011531284.1"
                     /db_xref="GeneID:5581"
                     /db_xref="HGNC:HGNC:9401"
                     /db_xref="MIM:176975"
                     /translation="MPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRC
                     ETNVAPNCGVDARGIAKVLADLGVTPDKITNSGQRRKKLIAGAESPQPASGSSPSEED
                     RSKSAPTSPCDQEIKELENNIRKALSFDNRGEEHRAASSPDGQLMSPGENGEVRQGQA
                     KRLGLDEFNFIKVLGKGSFGKVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKR
                     ILALARKHPYLTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEV
                     TSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYI
                     APEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFESILHDDVLYPVWLSK
                     EAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFFKEIDWVLLEQKKIKPPFKPRIK
                     TKRDVNNFDQDFTREEPVLTLVDEAIVKQINQEEFKGFSYFGEDLMP"
ORIGIN      
        1 atagctcaga gcaagcccag cccaactgag gcagaaataa tgccccattc cagccacaga
       61 tacttccaat taccagggca gacccagctg tctgaccttc acttgctaca tttggtcatg
      121 aactgagtgg tcggtcttac agatccaggt ctcctctaag tccatgggca aaggccactg
      181 agctctaggt tccctggggt ggagcctgaa tagcttctgg ttcccactgg gctgggaact
      241 tcagggagct ccctgaccat ctgtagttag tacactaagg acaggggtaa ggccgggttt
      301 gtgtgatagt tctgtgtcca tgctgacttt ctgtcttgcc ctgggaacac cactctggcc
      361 atggaaggaa cctctaatgt tggccttcac ctagacaacc tcttgaacct ctagttcggg
      421 gcacagactg gcttagaacc attggtggtc tttggactgc ccagggaaat atacctgcca
      481 gctgcagccc tcttccacag ttagagggcc cacagagcgt gtcctggtgc tgggagaaga
      541 ggaatgtcca ttctatccac aaggaaaggg gtgtcatagg aaagcaggga taccagtgtc
      601 aagtctgcac ctgcgtggtc cacaagcggt gccacgagct cataatcaca aagtgtgctg
      661 ggttaaagaa gcaggagacc cccgaccagg tgggctccca gcggttcagc gtcaacatgc
      721 cccacaagtt cggtatccac aactacaagg tccctacctt ctgcgatcac tgtgggtccc
      781 tgctctgggg actcttgcgg cagggtttgc agtgtaaagt ctgcaaaatg aatgttcacc
      841 gtcgatgtga gaccaacgtg gctcccaact gtggagtgga tgccagagga atcgccaaag
      901 tactggccga cctgggcgtt accccagaca aaatcaccaa cagcggccag agaaggaaaa
      961 agctcattgc tggtgccgag tccccgcagc ctgcttctgg aagctcacca tctgaggaag
     1021 atcgatccaa gtcagcaccc acctcccctt gtgaccagga aataaaagaa cttgagaaca
     1081 acattcggaa agccttgtca tttgacaacc gaggagagga gcaccgggca gcatcgtctc
     1141 ctgatggcca gctgatgagc cccggtgaga atggcgaagt ccggcaaggc caggccaagc
     1201 gcctgggcct ggatgagttc aacttcatca aggtgttggg caaaggcagc tttggcaagg
     1261 tcatgttggc agaactcaag ggcaaagatg aagtatatgc tgtgaaggtc ttaaagaagg
     1321 acgtcatcct tcaggatgat gacgtggact gcacaatgac agagaagagg attttggctc
     1381 tggcacggaa acacccgtac cttacccaac tctactgctg cttccagacc aaggaccgcc
     1441 tctttttcgt catggaatat gtaaatggtg gagacctcat gtttcagatt cagcgctccc
     1501 gaaaattcga cgagcctcgt tcacggttct atgctgcaga ggtcacatcg gccctcatgt
     1561 tcctccacca gcatggagtc atctacaggg atttgaaact ggacaacatc cttctggatg
     1621 cagaaggtca ctgcaagctg gctgacttcg ggatgtgcaa ggaagggatt ctgaatggtg
     1681 tgacgaccac cacgttctgt gggactcctg actacatagc tcctgagatc ctgcaggagt
     1741 tggagtatgg cccctccgtg gactggtggg ccctgggggt gctgatgtac gagatgatgg
     1801 ctggacagcc tccctttgag gccgacaatg aggacgacct atttgagtcc atcctccatg
     1861 acgacgtgct gtacccagtc tggctcagca aggaggctgt cagcatcttg aaagctttca
     1921 tgacgaagaa tccccacaag cgcctgggct gtgtggcatc gcagaatggc gaggacgcca
     1981 tcaagcagca cccattcttc aaagagattg actgggtgct cctggagcag aagaagatca
     2041 agccaccctt caaaccacgc attaaaacca aaagagacgt caataatttt gaccaagact
     2101 ttacccggga agagccggta ctcacccttg tggacgaagc aattgtaaag cagatcaacc
     2161 aggaggaatt caaaggtttc tcctactttg gtgaagacct gatgccctga gagcccactg
     2221 cagttggact ttgccgatgc tgcaagaagg ggtgcagaga agactcctgt gttggagaca
     2281 ctcagcaggt cttgaactac ttctcctcct cggagcccca gtcccatgtc cactgtctat
     2341 ttattgcatt cccttgcccc aggccacctc ctccccctcc cacctggtga ccagaaggcg
     2401 ctctcggttc ttgtctcacc agtaatgcag actcattggg tcagcaatta gctgtataca
     2461 ctgccgtgtt tggaccattg gcaagcctgg ttccactcct caggggctcc tggcagtgaa
     2521 gcaacttcag ttcttttact gcaaagaaca gaaaaaagaa agaaagcaaa caagaagact
     2581 ccggctctgc tatcggacac agatcctgat ccctcttgct tcttttccct cctgcaccgc
     2641 agcttgccat ccctgccctt ctgtcctgga gaagagactg gtgcttctcc gcacacacga
     2701 gggagggcgc ccttgaggca tgccctctga gggagggaga ccagagatgc agggattggc
     2761 cagctgggtt ggtttgctct ggaatggcta actcttgcct gctttggttt tagcttttca
     2821 gcatgccaaa gtcatgtaag tttgtgtctt gtggaagaaa tcctctttgt ggaaaaagaa
     2881 acagggtttt gaactctgtt aacatttgaa aaatatattt tcaaattcac tttctaattg
     2941 gccaaaagag atgagttcca gtctgaatac aggtagatat taaagggcta ataaaaaatg
     3001 agaaaccggt cgtccaaggt ggatgctgtc aatgcccgag tgacacatga gagctgtatg
     3061 aattgagaga aaaggcaaca agtagcattc ttcatcattc aagttctacc tggacacaaa
     3121 ggcgaggacc ctggggttcc aacaaagctc agctcccaga ttctctttcc agtttcatcc
     3181 taagttccta gcataaacac tatttatttt ctgcagcagt gtgttatttt tgcgcactta
     3241 tacaaaatgg tagtactact gtgttgtggt ttttaaacat taaacatgta aagttatata
     3301 cgaaatatct gcttttggaa taagcagaat gaggctaaac atgggttata caaagggtat
     3361 ctggaaactg aagagcaact tgttagaaaa ctgacaatgt cgcaagatgt actcagtttt
     3421 gtttctgtgt gacatgcaat ggcaactcat gtggacacta ttgaagggat gtgacattac
     3481 ctcctgtaga tatgctaaca gtgttattct ttcatttcca agggttctct gtggctttgt
     3541 gtatatgttt cccagaggtc atttgattac ctaatttact gaactgattt agcagggaat
     3601 ggaatccatt ccaactattg cacgtggatt tcccagctgc ccctaaatat atatacttgt
     3661 gagtggcaaa gtggcactaa tgaagctttt gccttttgta catttgagat ttttgtatat
     3721 agtgtttgct gcaaggcctg tggaattaat tcgttgcata tagaggtatc aactgctgca
     3781 tgttcaggca tattataaaa ctttagtcta tgaaagaata attataataa tgtccaggtg
     3841 caatactctg taagtctatt ggttcaagtt accgagagat aggtgtgttc ctttatgggg
     3901 gatggggggg tgtgttgggg attctttgta ttgtttattt cattttggtt tattttaaaa
     3961 gatgtaaaca tatattaagc tatattaaat ctcacataca gttcttctgt gctctattat
     4021 accctgatag agatggggga gagaaaggaa tgtttttgat ggtggtttca aagctcggac
     4081 agtaactatc ttgagcccat tagagagtct gtgtccatat ttgcatctgg ctggtcatag
     4141 cctttgttac taatgatgac attcagttct cttttgtttt tattttttaa aaactcaggt
     4201 gtaattatta tctgttctta agataattgc aaatattaaa tattatgata tatcaattca
     4261 tgtgtttggc ataccagtga atgatgaaga acatgagatt aatttaattt atcttcggta
     4321 acttgacatt ctggagagag actatcttct ggagttgagt acaagcacag aaacatcttt
     4381 acggtggcat catctcattt tttaggaaga catgataata ctgcccatca tattcatgtg
     4441 taactactgt tctttcttct gctttcttca ccataataaa ctttggacaa ccaagcaagc
     4501 tctaaccgca atgccagatg gccttgtccg agggcctagt gtttgcacgg cagtgggaac
     4561 tgggcctttc ctacaggaca actggcaagt ttgctgggaa gtcaaataat acattccacc
     4621 tggcagctga aggcagccag tcagtctgtc ccagaaaggg cccttttcag cacccaaagc
     4681 tgggctggct gggatgcctc tggctggtga agttctcaca taggctgatt taaatccagc
     4741 aaaggtctat agaaaaaggc ttgcgtgttc gttgagtaat cattgtttca ttttcatttt
     4801 tacgagagtt tgaaaataga cacactgtta acacttctgc cagttttttc tgatctttcc
     4861 agccccaccc cctttctctt tctctctctc tctcaaagaa aaaaaaaatg ggagtgcaaa
     4921 aaaaacaaag ccaaaaaata tatgaaggat agctgttctt ctgtgttctc tcattatgga
     4981 ctttgtgaag tagaaacata attttttttc ctccaaaggt gaaaaaacaa tgcattcttg
     5041 ctttaaaaaa aaaaaagaag gctaaaaaat tacctctttt taaattatgt gcaaaataat
     5101 tctggctaac tgtaaaatgt attcaatttt aggatttttt ttttttgtat tgtgatgctt
     5161 tatttgtaca tttttttcct ttctggatgt aattttaatc tcttgccatt cattagtgtt
     5221 atttcattgt aaacgttatt gtgccaaatg tactgtattc aaaaggatgt gaatgtgtat
     5281 tgtttcagaa cctaataaat acaatgacgt taagtctta
//
