LOCUS       XM_047436370            4518 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase cAMP-dependent type I
            regulatory subunit alpha (PRKAR1A), transcript variant X3, mRNA.
ACCESSION   XM_047436370
VERSION     XM_047436370.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4518
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..4518
                     /gene="PRKAR1A"
                     /gene_synonym="ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1;
                     PPNAD1; PRKAR1; Prkar1alpha; TSE1"
                     /note="protein kinase cAMP-dependent type I regulatory
                     subunit alpha; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 109 ESTs, 3904 long SRA
                     reads, 11 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 16 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5573"
                     /db_xref="HGNC:HGNC:9388"
                     /db_xref="MIM:188830"
     CDS             391..1536
                     /gene="PRKAR1A"
                     /gene_synonym="ACRDYS1; ADOHR; CAR; CNC; CNC1; PKR1;
                     PPNAD1; PRKAR1; Prkar1alpha; TSE1"
                     /codon_start=1
                     /product="cAMP-dependent protein kinase type I-alpha
                     regulatory subunit isoform X1"
                     /protein_id="XP_047292326.1"
                     /db_xref="GeneID:5573"
                     /db_xref="HGNC:HGNC:9388"
                     /db_xref="MIM:188830"
                     /translation="MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPE
                     RPMAFLREYFERLEKEEAKQIQNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISA
                     EVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIA
                     GETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAK
                     TNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQF
                     EDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRP
                     RAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV"
ORIGIN      
        1 gagtctgcat cctcaaggcc gtctgggcgt tggctttggt gcggggctcc ccagccgccc
       61 cgctcgcgct cgctgccccc accccacggc tcctggggcc ctgggccctc cgcggccctc
      121 cccggccgcc ttcgcccccg cgcgccgcgg cctcttcgct caccctcccc catttcctga
      181 aggacaacgg ctctatttta ctggggtccg ccatcgtctc gtccgccggt cctggctctt
      241 cttgtaagcc gttgactttt gtgccctggt aattctgtat cctgtttacc gtttacctac
      301 ttcccacgtc atcatgattt cttttgaggg agaactgaat gaaattccct taagggcctg
      361 acttcagcac ccgtctctgc agagagaacc atggagtctg gcagtaccgc cgccagtgag
      421 gaggcacgca gccttcgaga atgtgagctc tacgtccaga agcataacat tcaagcgctg
      481 ctcaaagatt ctattgtgca gttgtgcact gctcgacctg agagacccat ggcattcctc
      541 agggaatact ttgagaggtt ggagaaggag gaggcaaaac agattcagaa tctgcagaaa
      601 gcaggcactc gtacagactc aagggaggat gagatttctc ctcctccacc caacccagtg
      661 gttaaaggta ggaggcgacg aggtgctatc agcgctgagg tctacacgga ggaagatgcg
      721 gcatcctatg ttagaaaggt tataccaaaa gattacaaga caatggccgc tttagccaaa
      781 gccattgaaa agaatgtgct gttttcacat cttgatgata atgagagaag tgatattttt
      841 gatgccatgt tttcggtctc ctttatcgca ggagagactg tgattcagca aggtgatgaa
      901 ggggataact tctatgtgat tgatcaagga gagacggatg tctatgttaa caatgaatgg
      961 gcaaccagtg ttggggaagg agggagcttt ggagaacttg ctttgattta tggaacaccg
     1021 agagcagcca ctgtcaaagc aaagacaaat gtgaaattgt ggggcatcga ccgagacagc
     1081 tatagaagaa tcctcatggg aagcacactg agaaagcgga agatgtatga ggaattcctt
     1141 agtaaagtct ctattttaga gtctctggac aagtgggaac gtcttacggt agctgatgca
     1201 ttggaaccag tgcagtttga agatgggcag aagattgtgg tgcagggaga accaggggat
     1261 gagttcttca ttattttaga ggggtcagct gctgtgctac aacgtcggtc agaaaatgaa
     1321 gagtttgttg aagtgggaag attggggcct tctgattatt ttggtgaaat tgcactactg
     1381 atgaatcgtc ctcgtgctgc cacagttgtt gctcgtggcc ccttgaagtg cgttaagctg
     1441 gaccgaccta gatttgaacg tgttcttggc ccatgctcag acatcctcaa acgaaacatc
     1501 cagcagtaca acagttttgt gtcactgtct gtctgaaatc tgcctcctgt gcctcccttt
     1561 tctcctctcc ccaatccatg cttcactcat gcaaactgct ttattttccc tacttgcagc
     1621 gccaagtggc cactggcatc gcagcttcct gtctgtttat atattgaaag ttgcttttat
     1681 tgcaccattt tcaatttgga gcattaacta aatgctcata cacagttaaa taaatagaaa
     1741 gagttctatg gagactttgc tgttactgct tctctttgtg cagtgttagt attcaccctg
     1801 ggcagtgagt gccatgcttt ttggtgaggg cagatcccag cacctattga attaccatag
     1861 agtaatgatg taacagtgca agattttttt tttaagtgac ataattgtcc agttataagc
     1921 gtatttagac tgtggccata tatgctgtat ttctttgtag aataaatggt ttctcattaa
     1981 actctaaaga ttagggaaaa tggatataga aaatcttagt atagtagaaa gacatctgcc
     2041 tgtaattaaa ctagtttaag ggtggaaaaa tgcccatttt tgctaattat caatgggata
     2101 tgattggttc agtttttttt tttccagagt tgttgtttgc caagctaatc tgcctggttt
     2161 tatttatatc ttgttattaa tgtttcttct ccaattctga aatacttttg agtatggcta
     2221 tctatacctg ccttttaagt ttgaaactaa ctcatagatt gcaaatattg gttagtattt
     2281 aactacatct gcctcggctc acaaattccg attagacctt tatccagcta gtgccaaata
     2341 attgatcaga tgctgaattg agaataagaa tttgaggtct acattcttgg ttgttaattt
     2401 agagcgtttg gttaaagtat gtccttcagc tgactccagt ataatctcct ctgctcatta
     2461 aactgattcc aggagattgg atttgctgtg actagataca gatggagcaa atgtcctaac
     2521 agagaaatag aggtgatgct gctaaaggga gaaatgccag gcggacaaag ttcagtgtcg
     2581 ggaattttcc ccgtgacatt cactggggca tgagattttg gaagaagttt tttactttgg
     2641 tttagtcttt ttttccttcc tttttattca gctagaattt ctggtgggtt gatggtaggg
     2701 tataatgtgt ctgtgttgct tcaaattggt ctgaaaggct atcctgctga aagtcctgct
     2761 ttcctatcta gcatttattt ctctggcaaa cttttctttc ttttcttttt taaagtaaac
     2821 ttgtgtattg agtcttaact gtatttcagt attttccagc cttatgtgtt acattattcc
     2881 aatgataccc aacagtttat ttttattatt tttttaaaca aaatttcaca gttctgtaat
     2941 gtaggcactt ttattttcat tgtgatttat atataaggta atgtagggtt atatttggga
     3001 gtgactgcaa gcatttttcc atctgtgtgc aactaactga ctctgttatt gatcccttct
     3061 cctgcccttt cccaggtaat ttaaattggt catggtagat ttttttcata gatttgaaaa
     3121 acttttaggt tgttaccaag tatgaagtat aaatctgggg aagaggtttt atttacattt
     3181 tagggtgggt aagaaagcca ccttgttaca aattttttaa tttccaaaat aatctatatt
     3241 aaatgagggt ttctgatctg tactttgtgt ttagctacct ttttatattt aaaaaattaa
     3301 aaatgaaaat tacgttctta caagcttaaa gcttgatttg atctttgttt aaatgccaaa
     3361 atgtacttaa atgagttact tagaatgcca taaaattgca gtttcatgta tgtatataat
     3421 catgctcatg tatatttagt tacgtataat gctttctgag tgagttttac tcttaaatca
     3481 tttggttaaa tcatttggct tgctgtttac tcccttctgt agtttttaat taaaaacttt
     3541 aaagataagt ctacattaaa caatgatcac atctaaagct ttatctttgt gtaatctaag
     3601 tatatgtgag aaatcagaat tggcataatt tgtcttagtt gatattcaag gctttaaaag
     3661 tcattattcc tgggcttggt aagtgaattt atgagattta ctgctctaga aagtatagat
     3721 ggccaaagga ccgttttgta ttgcttcctg attaccagtc tgattatacc atgtgtgcta
     3781 atatactttt tttgttatag attgtcttaa tggtaggtca agtaataaaa agagatgaaa
     3841 taatttaaat tcttaaatga atcagttttt cttccctttc tcctttccgt ctttcctctc
     3901 tctgtccttc cccgaaagtc tactcgggtg ggcaaaaatg aaaaggggga aagtgaatta
     3961 tgggatcggt gttttgaaag agcaatgttt attttcagtg cttttcagtt tgtcaaagag
     4021 tggatctcaa aatcttgctt aaagggtaat tgagatgtag cagatttatt tacttagtca
     4081 tggaaagaaa aaaattcagt caaaagctaa agatttcctt ttgattgaag acagattggt
     4141 tctgtggcct tggaactttc ccagacttaa tggggaaaca tcatttctag attagcatac
     4201 tctttggttt aaatttaata tatacattta atgttactta gggatacttt tatattttgc
     4261 atatataaag cctcatatat aaagccttat ttctgatgct cttagatttc tgaggagtga
     4321 gatgattaag ttgtattcat tagtgtattg gtatttcttc acatccagtg aaattggaga
     4381 tatgttgtat gttagaagag cattctttaa attgtgttgc tttgaacatg tgtacctttt
     4441 ctagattcag taatcccttc cccccgtcct ctggagtatg aaacctttag agtcacaata
     4501 aaatgtaact aaagaaaa
//
