LOCUS       XM_047424681            4246 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein kinase cAMP-activated catalytic
            subunit beta (PRKACB), transcript variant X3, mRNA.
ACCESSION   XM_047424681
VERSION     XM_047424681.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4246
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..4246
                     /gene="PRKACB"
                     /gene_synonym="CAFD2; PKA C-beta; PKACB"
                     /note="protein kinase cAMP-activated catalytic subunit
                     beta; Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 26 ESTs, 1959 long SRA
                     reads, 55 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 27 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:5567"
                     /db_xref="HGNC:HGNC:9381"
                     /db_xref="MIM:176892"
     CDS             172..1053
                     /gene="PRKACB"
                     /gene_synonym="CAFD2; PKA C-beta; PKACB"
                     /codon_start=1
                     /product="cAMP-dependent protein kinase catalytic subunit
                     beta isoform X2"
                     /protein_id="XP_047280637.1"
                     /db_xref="GeneID:5567"
                     /db_xref="HGNC:HGNC:9381"
                     /db_xref="MIM:176892"
                     /translation="MLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP
                     FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS
                     LDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNK
                     AVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV
                     DLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEE
                     DIRVSITEKCAKEFGEF"
ORIGIN      
        1 actagtgccg ccattctaca tctcaccttg gaccctcctc aagtgaaaga gtttctagcc
       61 aaagccaaag aagacttttt gaaaaaatgg gagaatccaa ctcagaataa tgccggactt
      121 gaagattttg aaaggaaaaa aacccttgga acaggttcat ttggaagagt catgttggta
      181 aaacacaaag ccactgaaca gtattatgcc atgaagatct tagataagca gaaggttgtt
      241 aaactgaagc aaatagagca tactttgaat gagaaaagaa tattacaggc agtgaatttt
      301 cctttccttg ttcgactgga gtatgctttt aaggataatt ctaatttata catggttatg
      361 gaatatgtcc ctgggggtga aatgttttca catctaagaa gaattggaag gttcagtgag
      421 ccccatgcac ggttctatgc agctcagata gtgctaacat tcgagtacct ccattcacta
      481 gacctcatct acagagatct aaaacctgaa aatctcttaa ttgaccatca aggctatatc
      541 caggtcacag actttgggtt tgccaaaaga gttaaaggca gaacttggac attatgtgga
      601 actccagagt atttggctcc agaaataatt ctcagcaagg gctacaataa ggcagtggat
      661 tggtgggcat taggagtgct aatctatgaa atggcagctg gctatccccc attctttgca
      721 gaccaaccaa ttcagattta tgaaaagatt gtttctggaa aggtccgatt cccatcccac
      781 ttcagttcag atctcaagga ccttctacgg aacctgctgc aggtggattt gaccaagaga
      841 tttggaaatc taaagaatgg tgtcagtgat ataaaaactc acaagtggtt tgccacgaca
      901 gattggattg ctatttacca gaggaaggtt gaagctccat tcataccaaa gtttagaggc
      961 tctggagata ccagcaactt tgatgactat gaagaagaag atatccgtgt ctctataaca
     1021 gaaaaatgtg caaaagaatt tggtgaattt taaagaggaa caagatgaca tctgagctca
     1081 cactcagtgt ttgcactctg ttgagagata aggtagagct gagaccgtcc ttgttgaagc
     1141 agttacctag ttccttcatt ccaacgactg agtgaggtct ttattgccat catcccgtgt
     1201 gcgcactctg catccaccta tgtaacaagg caccgctaag caagcattgt ctgtgccata
     1261 acacagtact agaccacttt cttacttctc tttgggttgt ctttctcctc tcctatatcc
     1321 atttcttcct tttccaattt cattggtttt ctctaaacag tgctccattt tattttgttg
     1381 gtgtttcaga tgggcagtgt tatggctacg tgatatttga agggaaggat aagtgttgct
     1441 ttcagtagtt attgccaata ttgttgttgg tcaatggctt gaagataaac tttctaataa
     1501 ttattatttc tttgagtagc tcagacttgg ttttgccaaa actcttggta atttttgaag
     1561 atagactgtc ttatcaccaa ggaaatttat acaaattaag actaactttc ttggaattca
     1621 ctattctggc aataaatttt ggtagactaa tacagtacag ctagacccag aaatttggaa
     1681 ggctgtagat cagaggttct agttcccttt ccctcctttt atatcctcct ctccttgagt
     1741 aatgaagtga ccagcctgtg tagtgtgaca aacgtgtctc attcagcagg aaaaactaat
     1801 gatatggatc atcacccaga ttctctcact tggtaccagc atttctgtag gtattagaga
     1861 agagttctaa gttttctaaa ccttaactgt tccttaagga ttttagccag tattttaata
     1921 gaacatgatt aatgaaagtg acaaatttta aattttctct aatagtcctc atcataaact
     1981 ttttaaagga aaataagcaa actaaaaaga acattggttt agataaatac ttatactttg
     2041 caaagtcaaa aatggcttga tttttggaaa caatatagag gtattcatat ttaaatgagg
     2101 gtttacattt gttttgtttt gtaaccgtta aaaagaagtt gtttccagct aattattgtg
     2161 gtgtactata tttgtgagcc tagggtaggg gcactgctgc aacttctgct ttcatcccat
     2221 gcctcatcaa tgaggaaagg gaacaaagtg tataaaactg ccacaattgt attttaattt
     2281 tgaggtatga tattttcaga tatttcataa tttctaacct ctgttctctc agtaaacaga
     2341 atgtctgatc gatcatgcag atacaatgtt ggtatttgag aggttagttt ttttcctaca
     2401 cttttttttg ccaactgact taacaacatt gctgtcaggt ggaaatttca agcacttttg
     2461 cacatttagt tcagtgtttg ttgagaatcc atggcttaac ccacttgttt tgctattttt
     2521 ttctttgctt ttaattttcc ccatctgatt ttatctctgc gtttcagtga cctaccttaa
     2581 aacaacacac gagaagagtt aaactgggtt cattttaatg atcaatttac ctgcatataa
     2641 aatttatttt taatcaagct gatcttaatg tatataatca ttctatttgc tttattatcg
     2701 gtgcaggtag gtcattaaca ccacttcttt tcatctgtac cacaccctgg tgaaaccttt
     2761 gaagacataa aaaaaacctg tctgagatgt tctttctacc aatctatatg tctttcggtt
     2821 atcaagtgtt tctgcatggt aatgtcatgt aaatgctgat attgatttca ctggtccatc
     2881 tatatttaaa acgtgcaaga aaaaaataaa atactctgct ctagcaagtt ttgtgtaaca
     2941 aaggcatatc gtcatgttaa taaatttaaa acatcattcg tataaaatat tttaattttc
     3001 ttgtatttca tttagaccca agaacatgct gaccaatgtg ttctatatgt aaactacaaa
     3061 ttctatggta gctttgttgt atattattgt aaaattattt taataagtca tggggatgac
     3121 aatttgatta ttacaattta gttttcagta atcaaaaaga tttctatgaa ttctaaaaaa
     3181 tatttttttc tatgaaatta ctagtgccca gctgtagaat ctaccttagg tagatgatcc
     3241 ctagacatac gttggttttg agggctattc agccattcca ttttactctc tatttaaagg
     3301 ccgtgagcaa gcttgtcatg agcaaatatg tcaagggagt caatttctga ccaatcaagt
     3361 acactaaatt agaatatttt taaagtatgt aacattccca gtttcagcca caatttagcc
     3421 aagaataaga taaaaacttg aataagaagt aagtagcata aatcagtatt taacctaaaa
     3481 ttacatattt gaaacagaag atattatgtt atgctcagta aataattaag agatggcatt
     3541 gtgtaagaag gagccctaga ctgaaagtca agacatctga atttcaggct ggaaaactat
     3601 cagtatgatc tcagcctcag ttctcttgtc tgtaaaatgg aagaactgga ttaggcagtt
     3661 tgtaagattc ctcctaactt tcacagtcga tgacaagatt gtctttttat ctgatatttt
     3721 gaagggtata ttgctttgaa gtaagtctca ataaggcaat atattttagg gcatctttct
     3781 tcttatctct gacagtgttc ttaaaattat ttgaatatca taagagcctt ggtgtctgtc
     3841 ctaattcctt tctcactcac cgatgctgaa tacccagttg aatcaaactg tcaacctacc
     3901 aaaaacgata ttgtggctta tgggtattgc tgtctcattc ttggtatatt cttgtgttaa
     3961 ctgcccattg gcctgaaaat actcattgta agcctgaaaa aaaaaatctt tcccactgtt
     4021 ttttctgctt gttgtaagaa tcaaatgaaa taatgtatgt gaaagcacct tgtaaactgt
     4081 aacctatcaa tgtaaaatgt taaggtgtgt tgttatttca ttaattactt ctttgtttag
     4141 aatggaattt cctatgcact actgtagcta ggaaatgctg aaaacaactg tgttttttaa
     4201 ttaatcaata actgcaaaat taaagtacct tcaatggata agacaa
//
