LOCUS       XM_047449753            1331 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens primase and DNA directed polymerase
            (PRIMPOL), transcript variant X9, mRNA.
ACCESSION   XM_047449753
VERSION     XM_047449753.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1331
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..1331
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /note="primase and DNA directed polymerase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 ESTs, 66 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 51 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:201973"
                     /db_xref="HGNC:HGNC:26575"
                     /db_xref="MIM:615421"
     CDS             309..1244
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /codon_start=1
                     /product="DNA-directed primase/polymerase protein isoform
                     X7"
                     /protein_id="XP_047305709.1"
                     /db_xref="GeneID:201973"
                     /db_xref="HGNC:HGNC:26575"
                     /db_xref="MIM:615421"
                     /translation="MNRKWEAKLKQIEERASHYERKPLSSVYRPRLSKPEEPPSIWRL
                     FHRQAQAFNFVKSCKEDVHVFALECKVGDGQRIYLVTTYAEFWFYYKSRKNLLHCYEV
                     IPENAVCKLYFDLEFNKPANPGADGKKMVALLIEYVCKALQELYGVNCSAEDVLNLDS
                     STDEKFSRHLIFQLHDVAFKDNIHVGNFLRKILQPALDLLGSEDDDSAPETTGHGFPH
                     FSEAPARQGFSFNKMFTEKATEESWTSNSKKLERLGSAEQSSPDLSFLVVKNNMGEKH
                     LFVDLGSQILYEFLHVSHLRINKKELDILTVSALQ"
     polyA_site      1331
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gtcttcctga gagtccgcgg gcttccgctc ccagcgcggg attctggagg gaaattgagg
       61 gagacttgga aaccgcgcca ggcccaacgg gtacctagaa gggagacaaa gccaggcctg
      121 ctgcccagtt tgagctctgg gaagaagagg agcaggccgg gacgcccacc gaggtatccc
      181 agaggtgaca gaacttgatc tgggcctgga aggggaagaa ttcgggaaaa gcaacgtggg
      241 gcattccagt agtaattgat agaaatatta cgtgggatag gatttattct ctccacactt
      301 ctgaaccaat gaatagaaaa tgggaagcaa aactgaagca aattgaagaa cgagcatctc
      361 attatgagag gaaaccgttg tcctcagtgt atagaccaag attgtccaag ccagaagaac
      421 caccctccat ctggagacta tttcatcgac aagctcaagc ttttaatttt gttaaaagct
      481 gtaaagaaga cgttcatgta tttgctttgg aatgcaaagt aggagatgga caacgtattt
      541 accttgtgac aacctatgct gaattttggt tttactataa atccagaaaa aatctcttac
      601 actgctatga agttattcct gaaaatgctg tgtgcaagct ttattttgat ttggaattta
      661 acaaacctgc caacccagga gctgatggga aaaagatggt tgcattactc attgagtatg
      721 tgtgtaaagc acttcaagag ttatacggtg ttaattgctc agctgaagat gttttgaact
      781 tggattctag cactgatgaa aaattcagcc ggcatttaat atttcagctc catgatgtgg
      841 catttaaaga taatattcat gttggtaatt ttttgagaaa aattttgcag cctgctcttg
      901 acttgcttgg cagtgaagat gatgatagcg ctccagagac aacaggccat ggatttcccc
      961 atttttcaga agcacctgca agacaaggat tttctttcaa taaaatgttc acagaaaagg
     1021 ctacagagga aagctggaca tcgaattcaa agaaactgga gaggctgggg tcagctgagc
     1081 aaagcagtcc tgacctttca tttctagttg tgaagaataa catgggagag aagcatcttt
     1141 ttgtagatct cggttctcag atactttacg aattcttaca tgtgagccat ctcagaataa
     1201 acaaaaagga gttggatatt ttaacagtat cggcacttca gtagaaacca ttgaaggttt
     1261 tcagtgttct ccctatcctg aagttgatca ttttgttctt tctttggtga ataaagatgg
     1321 cattaaagga g
//
