LOCUS       XM_011531726            1686 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens primase and DNA directed polymerase
            (PRIMPOL), transcript variant X6, mRNA.
ACCESSION   XM_011531726
VERSION     XM_011531726.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011531726.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..1686
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /note="primase and DNA directed polymerase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 23 ESTs, 41 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 10 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:201973"
                     /db_xref="HGNC:HGNC:26575"
                     /db_xref="MIM:615421"
     CDS             317..1513
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /codon_start=1
                     /product="DNA-directed primase/polymerase protein isoform
                     X4"
                     /protein_id="XP_011530028.1"
                     /db_xref="GeneID:201973"
                     /db_xref="HGNC:HGNC:26575"
                     /db_xref="MIM:615421"
                     /translation="MLNFGFTINPGNFLRKILQPALDLLGSEDDDSAPETTGHGFPHF
                     SEAPARQGFSFNKMFTEKATEESWTSNSKKLERLGSAEQSSPDLSFLVVKNNMGEKHL
                     FVDLGVYTRNRNFRLYKSSKIGKRVALEVTEDNKFFPIQSKDVSDEYQYFLSSLVSNV
                     RFSDTLRILTCEPSQNKQKGVGYFNSIGTSVETIEGFQCSPYPEVDHFVLSLVNKDGI
                     KGGIRRWNYFFPEELLVYDICKYRWCENIGRAHKSNNIISFCVIFGNHRFDWILVDLK
                     NEVWYQKCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFTTDEADETRSNETQNPH
                     KPSPSRLSTGASADAVWDNGIDDAYFLEATEDAELAEAAENSLLSYNSEVDEIPDELI
                     IEVLQE"
ORIGIN      
        1 gtcttcctga gagtccgcgg gcttccgctc ccagcgcggg attctggagg gaaattgagg
       61 gagacttgga aaccgcgcca ggcccaacgg gtacctagaa gggagacaaa gccaggcctg
      121 ctgcccagtt tgagctctgg gaagaagagg agcaggccgg gacgcccacc gaggtatccc
      181 agaggtgaca gaacttgatc tgggcctgga aggggaagaa ttcgggaaaa gcaacgtggg
      241 gcattccagg acgttcatgt atttgctttg gaatgcaaag taggagatgg acaacgtatt
      301 taccttgtga caacctatgc tgaattttgg ttttactata aatccaggta attttttgag
      361 aaaaattttg cagcctgctc ttgacttgct tggcagtgaa gatgatgata gcgctccaga
      421 gacaacaggc catggatttc cccatttttc agaagcacct gcaagacaag gattttcttt
      481 caataaaatg ttcacagaaa aggctacaga ggaaagctgg acatcgaatt caaagaaact
      541 ggagaggctg gggtcagctg agcaaagcag tcctgacctt tcatttctag ttgtgaagaa
      601 taacatggga gagaagcatc tttttgtaga tctcggagtt tatacaagaa atagaaactt
      661 tcggctatat aaatcatcaa aaattggaaa gcgtgtggct ttggaggtta ctgaagataa
      721 caaatttttt cctatacagt caaaagatgt ttctgacgaa tatcaatatt ttctctcttc
      781 tttggtcagc aatgtcaggt tctcagatac tttacgaatt cttacatgtg agccatctca
      841 gaataaacaa aaaggagttg gatattttaa cagtatcggc acttcagtag aaaccattga
      901 aggttttcag tgttctccct atcctgaagt tgatcatttt gttctttctt tggtgaataa
      961 agatggcatt aaaggaggaa ttcggcgttg gaactacttt ttcccagaag aattactggt
     1021 ttatgatatt tgtaaatatc ggtggtgtga aaacattgga agagcccata agagtaataa
     1081 tataatttca ttttgtgtga tttttggcaa ccaccgtttt gattggattc tggttgatct
     1141 gaaaaatgaa gtttggtatc aaaaatgtca tgaccctgta tgtaaagcag aaaacttcaa
     1201 atctgactgt ttcccattac ctgctgaagt atgtctcctg tttcttttca aagaggaaga
     1261 agagtttaca acagatgaag cagatgaaac taggagcaat gaaacccaga atcctcataa
     1321 accatcacct agcaggctgt caacaggtgc atctgctgat gctgtctggg ataatggcat
     1381 tgatgatgct tattttttag aagctactga agatgctgaa ttagctgaag ctgcagagaa
     1441 cagtcttctc agttataaca gtgaagtgga tgaaattcct gatgaactaa ttatagaagt
     1501 attacaagag taactaattc actatgaaca cttttgtcac caggctataa tttgcctgat
     1561 gtctgtgaga tttgataaat atatcattca acctgtttat ataaactaag ttttattact
     1621 ttgctttcca atttttgttt tttacttctg taaaccaatt tcattaaaaa ttagctttgg
     1681 tgtaaa
//
