LOCUS       XM_011531720            2200 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens primase and DNA directed polymerase
            (PRIMPOL), transcript variant X1, mRNA.
ACCESSION   XM_011531720
VERSION     XM_011531720.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011531720.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2200
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..2200
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /note="primase and DNA directed polymerase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 31 ESTs, 61 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 34 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:201973"
                     /db_xref="HGNC:HGNC:26575"
                     /db_xref="MIM:615421"
     CDS             306..2027
                     /gene="PRIMPOL"
                     /gene_synonym="CCDC111; MYP22; Primpol1"
                     /codon_start=1
                     /product="DNA-directed primase/polymerase protein isoform
                     X1"
                     /protein_id="XP_011530022.1"
                     /db_xref="GeneID:201973"
                     /db_xref="HGNC:HGNC:26575"
                     /db_xref="MIM:615421"
                     /translation="MNRKWEAKLKQIEERASHYERKPLSSVYRPRLSKPEEPPSIWRL
                     FHRQAQAFNFVKSCKEDVHVFALECKVGDGQRIYLVTTYAEFWFYYKSRKNLLHCYEV
                     IPENAVCKLYFDLEFNKPANPGADGKKMVALLIEYVCKALQELYGVNCSAEDVLNLDS
                     STDEKFSRHLIFQLHDVAFKDNIHVGNFLRKILQPALDLLGSEDDDSAPETTGHGFPH
                     FSEAPARQGFSFNKMFTEKATEESWTSNSKKLERLGSAEQSSPDLSFLVVKNNMGEKH
                     LFVDLGVYTRNRNFRLYKSSKIGKRVALEVTEDNKFFPIQSKDVSDEYQYFLSSLVSN
                     VRFSDTLRILTCEPSQNKQKGVGYFNSIGTSVETIEGFQCSPYPEVDHFVLSLVNKDG
                     IKGGIRRWNYFFPEELLVYDICKYRWCENIGRAHKSNNIISFCVIFGNHRFDWILVDL
                     KNEVWYQKCHDPVCKAENFKSDCFPLPAEVCLLFLFKEEEEFTTDEADETRSNETQNP
                     HKPSPSRLSTGASADAVWDNGIDDAYFLEATEDAELAEAAENSLLSYNSEVDEIPDEL
                     IIEVLQE"
ORIGIN      
        1 gtcttcctga gagtccgcgg gcttccgctc ccagcgcggg attctggagg gaaattgagg
       61 gagacttgga aaccgcgcca ggcccaacgg gtacctagaa gggagacaaa gccaggcctg
      121 ctgcccagtt tgagctctgg gaagaagagg agcaggccgg gacgcccacc gaggtatccc
      181 agaggtgaca gaacttgatc tgggcctgga aggggaagaa ttcgggaaaa gcaacgtggg
      241 gcattccagt aattgataga aatattacgt gggataggat ttattctctc cacacttctg
      301 aaccaatgaa tagaaaatgg gaagcaaaac tgaagcaaat tgaagaacga gcatctcatt
      361 atgagaggaa accgttgtcc tcagtgtata gaccaagatt gtccaagcca gaagaaccac
      421 cctccatctg gagactattt catcgacaag ctcaagcttt taattttgtt aaaagctgta
      481 aagaagacgt tcatgtattt gctttggaat gcaaagtagg agatggacaa cgtatttacc
      541 ttgtgacaac ctatgctgaa ttttggtttt actataaatc cagaaaaaat ctcttacact
      601 gctatgaagt tattcctgaa aatgctgtgt gcaagcttta ttttgatttg gaatttaaca
      661 aacctgccaa cccaggagct gatgggaaaa agatggttgc attactcatt gagtatgtgt
      721 gtaaagcact tcaagagtta tacggtgtta attgctcagc tgaagatgtt ttgaacttgg
      781 attctagcac tgatgaaaaa ttcagccggc atttaatatt tcagctccat gatgtggcat
      841 ttaaagataa tattcatgtt ggtaattttt tgagaaaaat tttgcagcct gctcttgact
      901 tgcttggcag tgaagatgat gatagcgctc cagagacaac aggccatgga tttccccatt
      961 tttcagaagc acctgcaaga caaggatttt ctttcaataa aatgttcaca gaaaaggcta
     1021 cagaggaaag ctggacatcg aattcaaaga aactggagag gctggggtca gctgagcaaa
     1081 gcagtcctga cctttcattt ctagttgtga agaataacat gggagagaag catctttttg
     1141 tagatctcgg agtttataca agaaatagaa actttcggct atataaatca tcaaaaattg
     1201 gaaagcgtgt ggctttggag gttactgaag ataacaaatt ttttcctata cagtcaaaag
     1261 atgtttctga cgaatatcaa tattttctct cttctttggt cagcaatgtc aggttctcag
     1321 atactttacg aattcttaca tgtgagccat ctcagaataa acaaaaagga gttggatatt
     1381 ttaacagtat cggcacttca gtagaaacca ttgaaggttt tcagtgttct ccctatcctg
     1441 aagttgatca ttttgttctt tctttggtga ataaagatgg cattaaagga ggaattcggc
     1501 gttggaacta ctttttccca gaagaattac tggtttatga tatttgtaaa tatcggtggt
     1561 gtgaaaacat tggaagagcc cataagagta ataatataat ttcattttgt gtgatttttg
     1621 gcaaccaccg ttttgattgg attctggttg atctgaaaaa tgaagtttgg tatcaaaaat
     1681 gtcatgaccc tgtatgtaaa gcagaaaact tcaaatctga ctgtttccca ttacctgctg
     1741 aagtatgtct cctgtttctt ttcaaagagg aagaagagtt tacaacagat gaagcagatg
     1801 aaactaggag caatgaaacc cagaatcctc ataaaccatc acctagcagg ctgtcaacag
     1861 gtgcatctgc tgatgctgtc tgggataatg gcattgatga tgcttatttt ttagaagcta
     1921 ctgaagatgc tgaattagct gaagctgcag agaacagtct tctcagttat aacagtgaag
     1981 tggatgaaat tcctgatgaa ctaattatag aagtattaca agagtaacta attcactatg
     2041 aacacttttg tcaccaggct ataatttgcc tgatgtctgt gagatttgat aaatatatca
     2101 ttcaacctgt ttatataaac taagttttat tactttgctt tccaattttt gttttttact
     2161 tctgtaaacc aatttcatta aaaattagct ttggtgtaaa
//
