LOCUS       NM_021620               3129 bp    mRNA    linear   PRI 23-APR-2024
DEFINITION  Homo sapiens PR/SET domain 13 (PRDM13), mRNA.
ACCESSION   NM_021620
VERSION     NM_021620.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3129)
  AUTHORS   Seo,Y., Joo,K., Lee,J., Diaz,A., Jang,S., Cherry,T.J.,
            Bujakowska,K.M., Han,J., Woo,S.J. and Small,K.W.
  TITLE     Two novel non-coding single nucleotide variants in the DNase1
            hypersensitivity site of PRDM13 causing North Carolina macular
            dystrophy in Korea
  JOURNAL   Mol Vis 30, 58-66 (2024)
   PUBMED   38601016
  REMARK    GeneRIF: Two novel non-coding single nucleotide variants in the
            DNase1 hypersensitivity site of PRDM13 causing North Carolina
            macular dystrophy in Korea.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3129)
  AUTHORS   Whittaker,D.E., Oleari,R., Gregory,L.C., Le Quesne-Stabej,P.,
            Williams,H.J., Torpiano,J.G., Formosa,N., Cachia,M.J., Field,D.,
            Lettieri,A., Ocaka,L.A., Paganoni,A.J., Rajabali,S.H.,
            Riegman,K.L., De Martini,L.B., Chaya,T., Robinson,I.C.,
            Furukawa,T., Cariboni,A., Basson,M.A. and Dattani,M.T.
  CONSRTM   GOSgene
  TITLE     A recessive PRDM13 mutation results in congenital hypogonadotropic
            hypogonadism and cerebellar hypoplasia
  JOURNAL   J Clin Invest 131 (24) (2021)
   PUBMED   34730112
  REMARK    GeneRIF: A recessive PRDM13 mutation results in congenital
            hypogonadotropic hypogonadism and cerebellar hypoplasia.
REFERENCE   3  (bases 1 to 3129)
  AUTHORS   Small,K.W., Van de Sompele,S., Nuytemans,K., Vincent,A.,
            Yuregir,O.O., Ciloglu,E., Sariyildiz,C., Rosseel,T., Avetisjan,J.,
            Udar,N., Vance,J.M., Pericak-Vance,M.A., De Baere,E. and Shaya,F.S.
  TITLE     A novel duplication involving PRDM13 in a Turkish family supports
            its role in North Carolina macular dystrophy (NCMD/MCDR1)
  JOURNAL   Mol Vis 27, 518-527 (2021)
   PUBMED   34526759
  REMARK    GeneRIF: A novel duplication involving PRDM13 in a Turkish family
            supports its role in North Carolina macular dystrophy (NCMD/MCDR1).
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3129)
  AUTHORS   Green,D.J., Lenassi,E., Manning,C.S., McGaughey,D., Sharma,V.,
            Black,G.C., Ellingford,J.M. and Sergouniotis,P.I.
  TITLE     North Carolina Macular Dystrophy: Phenotypic Variability and
            Computational Analysis of Disease-Associated Noncoding Variants
  JOURNAL   Invest Ophthalmol Vis Sci 62 (7), 16 (2021)
   PUBMED   34125159
  REMARK    GeneRIF: North Carolina Macular Dystrophy: Phenotypic Variability
            and Computational Analysis of Disease-Associated Noncoding
            Variants.
REFERENCE   5  (bases 1 to 3129)
  AUTHORS   Namburi,P., Khateb,S., Meyer,S., Bentovim,T., Ratnapriya,R.,
            Khramushin,A., Swaroop,A., Schueler-Furman,O., Banin,E. and
            Sharon,D.
  TITLE     A unique PRDM13-associated variant in a Georgian Jewish family with
            probable North Carolina macular dystrophy and the possible
            contribution of a unique CFH variant
  JOURNAL   Mol Vis 26, 299-310 (2020)
   PUBMED   32476814
  REMARK    GeneRIF: A unique PRDM13-associated variant in a Georgian Jewish
            family with probable North Carolina macular dystrophy and the
            possible contribution of a unique CFH variant.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3129)
  AUTHORS   Small,K.W., DeLuca,A.P., Whitmore,S.S., Rosenberg,T.,
            Silva-Garcia,R., Udar,N., Puech,B., Garcia,C.A., Rice,T.A.,
            Fishman,G.A., Heon,E., Folk,J.C., Streb,L.M., Haas,C.M.,
            Wiley,L.A., Scheetz,T.E., Fingert,J.H., Mullins,R.F., Tucker,B.A.
            and Stone,E.M.
  TITLE     North Carolina Macular Dystrophy Is Caused by Dysregulation of the
            Retinal Transcription Factor PRDM13
  JOURNAL   Ophthalmology 123 (1), 9-18 (2016)
   PUBMED   26507665
REFERENCE   7  (bases 1 to 3129)
  AUTHORS   Satoh,A., Brace,C.S., Rensing,N. and Imai,S.
  TITLE     Deficiency of Prdm13, a dorsomedial hypothalamus-enriched gene,
            mimics age-associated changes in sleep quality and adiposity
  JOURNAL   Aging Cell 14 (2), 209-218 (2015)
   PUBMED   25546159
  REMARK    GeneRIF: Findings indicate that Prdm13/Nkx2-1-mediated signaling in
            the DMC declines with advanced age, leading to decreased sleep
            quality and increased adiposity.
REFERENCE   8  (bases 1 to 3129)
  AUTHORS   Elks,C.E., Perry,J.R., Sulem,P., Chasman,D.I., Franceschini,N.,
            He,C., Lunetta,K.L., Visser,J.A., Byrne,E.M., Cousminer,D.L.,
            Gudbjartsson,D.F., Esko,T., Feenstra,B., Hottenga,J.J.,
            Koller,D.L., Kutalik,Z., Lin,P., Mangino,M., Marongiu,M.,
            McArdle,P.F., Smith,A.V., Stolk,L., van Wingerden,S.H., Zhao,J.H.,
            Albrecht,E., Corre,T., Ingelsson,E., Hayward,C., Magnusson,P.K.,
            Smith,E.N., Ulivi,S., Warrington,N.M., Zgaga,L., Alavere,H.,
            Amin,N., Aspelund,T., Bandinelli,S., Barroso,I., Berenson,G.S.,
            Bergmann,S., Blackburn,H., Boerwinkle,E., Buring,J.E., Busonero,F.,
            Campbell,H., Chanock,S.J., Chen,W., Cornelis,M.C., Couper,D.,
            Coviello,A.D., d'Adamo,P., de Faire,U., de Geus,E.J., Deloukas,P.,
            Doring,A., Smith,G.D., Easton,D.F., Eiriksdottir,G., Emilsson,V.,
            Eriksson,J., Ferrucci,L., Folsom,A.R., Foroud,T., Garcia,M.,
            Gasparini,P., Geller,F., Gieger,C., Gudnason,V., Hall,P.,
            Hankinson,S.E., Ferreli,L., Heath,A.C., Hernandez,D.G., Hofman,A.,
            Hu,F.B., Illig,T., Jarvelin,M.R., Johnson,A.D., Karasik,D.,
            Khaw,K.T., Kiel,D.P., Kilpelainen,T.O., Kolcic,I., Kraft,P.,
            Launer,L.J., Laven,J.S., Li,S., Liu,J., Levy,D., Martin,N.G.,
            McArdle,W.L., Melbye,M., Mooser,V., Murray,J.C., Murray,S.S.,
            Nalls,M.A., Navarro,P., Nelis,M., Ness,A.R., Northstone,K.,
            Oostra,B.A., Peacock,M., Palmer,L.J., Palotie,A., Pare,G.,
            Parker,A.N., Pedersen,N.L., Peltonen,L., Pennell,C.E., Pharoah,P.,
            Polasek,O., Plump,A.S., Pouta,A., Porcu,E., Rafnar,T., Rice,J.P.,
            Ring,S.M., Rivadeneira,F., Rudan,I., Sala,C., Salomaa,V., Sanna,S.,
            Schlessinger,D., Schork,N.J., Scuteri,A., Segre,A.V.,
            Shuldiner,A.R., Soranzo,N., Sovio,U., Srinivasan,S.R.,
            Strachan,D.P., Tammesoo,M.L., Tikkanen,E., Toniolo,D., Tsui,K.,
            Tryggvadottir,L., Tyrer,J., Uda,M., van Dam,R.M., van Meurs,J.B.,
            Vollenweider,P., Waeber,G., Wareham,N.J., Waterworth,D.M.,
            Weedon,M.N., Wichmann,H.E., Willemsen,G., Wilson,J.F., Wright,A.F.,
            Young,L., Zhai,G., Zhuang,W.V., Bierut,L.J., Boomsma,D.I.,
            Boyd,H.A., Crisponi,L., Demerath,E.W., van Duijn,C.M., Econs,M.J.,
            Harris,T.B., Hunter,D.J., Loos,R.J., Metspalu,A., Montgomery,G.W.,
            Ridker,P.M., Spector,T.D., Streeten,E.A., Stefansson,K.,
            Thorsteinsdottir,U., Uitterlinden,A.G., Widen,E., Murabito,J.M.,
            Ong,K.K. and Murray,A.
  CONSRTM   GIANT Consortium
  TITLE     Thirty new loci for age at menarche identified by a meta-analysis
            of genome-wide association studies
  JOURNAL   Nat Genet 42 (12), 1077-1085 (2010)
   PUBMED   21102462
REFERENCE   9  (bases 1 to 3129)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
REFERENCE   10 (bases 1 to 3129)
  AUTHORS   Behrends,U., Schneider,I., Rossler,S., Frauenknecht,H., Golbeck,A.,
            Lechner,B., Eigenstetter,G., Zobywalski,C., Muller-Weihrich,S.,
            Graubner,U., Schmid,I., Sackerer,D., Spath,M., Goetz,C., Prantl,F.,
            Asmuss,H.P., Bise,K. and Mautner,J.
  TITLE     Novel tumor antigens identified by autologous antibody screening of
            childhood medulloblastoma cDNA libraries
  JOURNAL   Int J Cancer 106 (2), 244-251 (2003)
   PUBMED   12800201
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL137784.14 and AL035087.20.
            
            On Nov 22, 2019 this sequence version replaced NM_021620.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000369215.5/ ENSP00000358217.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-346               AL137784.14        124350-124695
            347-478             AL137784.14        126258-126389
            479-599             AL137784.14        126704-126824
            600-3129            AL035087.20        3237-5766
FEATURES             Location/Qualifiers
     source          1..3129
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q16.2"
     gene            1..3129
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /note="PR/SET domain 13"
                     /db_xref="GeneID:59336"
                     /db_xref="HGNC:HGNC:13998"
                     /db_xref="MIM:616741"
     exon            1..346
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..2326
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /note="PR-domain containing protein 13; PR domain
                     containing 13; PR domain 13"
                     /codon_start=1
                     /product="PR domain zinc finger protein 13"
                     /protein_id="NP_067633.2"
                     /db_xref="CCDS:CCDS43487.1"
                     /db_xref="GeneID:59336"
                     /db_xref="HGNC:HGNC:13998"
                     /db_xref="MIM:616741"
                     /translation="MHGAARAPATSVSADCCIPAGLRLGPVPGTFKLGKYLSDRREPG
                     PKKKVRMVRGELVDESGGSPLEWIGLIRAARNSQEQTLEAIADLPGGQIFYRALRDVQ
                     PGEELTVWYSNSLAQWFDIPTTATPTHDEKGEERYICWYCWRTFRYPNSLKAHLRFHC
                     VFSGGGGGAFLHHEHAARQGAVPAADGLGLSPKPPAPDFAAPSQAGTLRPHPLGPPPV
                     QACGAREGIKREASSAPSATSPTPGKWGQPKKGKEQLDRALDMSGAARGQGHFLGIVG
                     GSSAGVGSLAFYPGVRSAFKPAGLARAAAAAHGDPYREESSSKQGAGLALGRLLGGGR
                     ACGRPGSGENSAAGGAGHHHHHHAHHHHHPKCLLAGDPPPPPPPGLPCSGALRGFPLL
                     SVPPEEASAFKHVERAPPAAAALPGARYAQLPPAPGLPLERCALPPLDPGGLKAYPGG
                     ECSHLPAVMPAFTVYNGELLYGSPATTAYYPLKLHFGGLLKYPESISYFSGPAAAALS
                     PAELGSLASIDREIAMHNQQLSEMAAGKGRGRLDSGTLPPAVAAAGGTGGGGSGGSGA
                     GKPKTGHLCLYCGKLYSRKYGLKIHMRTHTGYKPLKCKVCLRPFGDPSNLNKHIRLHA
                     EGNTPYRCEFCGKVLVRRRDLERHVKSRHPGQSLLAKAGDGPGAEPGYPPEPGDPKSD
                     DSDVDVCFTDDQSDPEVGGGGERDL"
     exon            347..478
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /inference="alignment:Splign:2.1.0"
     exon            479..599
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /inference="alignment:Splign:2.1.0"
     exon            600..3129
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3111..3116
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /note="hexamer: AATAAA"
     polyA_site      3129
                     /gene="PRDM13"
                     /gene_synonym="CDIDHH; MU-MB-20.220; PCH17; PFM10"
                     /note="major polyA site"
ORIGIN      
        1 actccgcgcc cttgcgctag cggtgccaaa aggctcccgc cccgattgaa aaggcgcagt
       61 gcatgcccgc ccgcgtcact ccgcgggcgg aggacgcacg tcggggcgcg gctctctggc
      121 tagcgcgcag ctccagctct gtcactcgcg cccttccaag gacctggagc acccgagcgc
      181 ctgcctggtg gcggcggcaa caatgcacgg agccgccaga gcgccagcca ccagcgtgag
      241 tgccgactgc tgcatcccgg ccggcttgcg cctcggaccg gtgcctggta ccttcaagct
      301 gggcaagtac ctgtcagacc gcagggagcc cgggcctaag aaaaaggtgc gcatggtgag
      361 aggggagctg gtggacgagt cggggggctc ccctctggag tggatagggt taatccgggc
      421 agccagaaac tcccaggaac agactctgga agctattgca gacttacccg gaggacagat
      481 cttctaccga gcattgcgag acgtccagcc aggggaggag ctgacagtgt ggtattctaa
      541 ctccttggct cagtggttcg acatccccac cacagcgact ccgactcacg acgagaaagg
      601 ggaggagcgc tacatctgct ggtactgctg gaggacgttt agatacccca acagccttaa
      661 ggcacacctg cgtttccact gcgtgttcag cggcggtgga ggcggcgcct tcctgcacca
      721 cgaacacgcg gctcgccaag gcgccgtccc agcggctgat ggcctcggtc tctccccaaa
      781 acccccggcg cccgatttcg ccgcgccttc ccaggcagga actttgcgac cccaccccct
      841 gggcccgcca ccagttcagg cctgcggtgc gcgggagggc atcaagcgcg aggcctcttc
      901 cgcgccctcg gccacctcgc cgaccccagg caagtggggg cagcccaaga agggcaagga
      961 gcagctggac cgtgccctgg acatgagcgg agccgcccga ggacaagggc acttcctcgg
     1021 catcgtgggc ggctcctcgg cgggggtcgg cagcctggct ttctaccccg gcgtgcgctc
     1081 agctttcaag cccgccggcc tagcgagggc ggcggcggcc gctcacggcg acccctaccg
     1141 ggaggagagc agcagcaagc aaggagccgg cctcgctttg ggcaggctgc tgggcggggg
     1201 ccgggcgtgc gggcgccccg ggagcgggga gaactcggcg gcgggcggcg cgggtcacca
     1261 ccatcaccac cacgcgcacc accaccacca tcccaagtgc ctgctcgctg gggacccgcc
     1321 gccgccgccg ccgcctggcc tgccctgctc tggggccctg cgcggcttcc ctctgctctc
     1381 cgtccccccg gaagaggcgt ccgccttcaa gcacgtggag cgcgccccgc ccgcagccgc
     1441 cgcgctgcca ggagcgcgtt atgcgcagct gccccctgcg ccggggttgc ccctcgagcg
     1501 ctgcgcgctg ccgcccctcg acccgggcgg tctcaaagcc tatccgggtg gtgagtgcag
     1561 ccacctgccc gccgtcatgc cggcctttac agtctacaac ggggagctgc tctacggctc
     1621 accggccacc accgcttatt acccgctcaa attgcacttc ggcgggctgc tgaagtatcc
     1681 ggagtccatc tcctacttca gcgggcctgc agcggccgcc ctaagccccg ccgagctggg
     1741 gtcgctggcc agcatcgacc gagagatcgc catgcacaat cagcagctgt ccgagatggc
     1801 tgccgggaag ggtcgcggac gcctggactc ggggacgttg ccaccggccg tcgcggcggc
     1861 gggaggcacc gggggcggcg gcagcggagg cagcggcgca ggtaagccca agaccggcca
     1921 cctgtgcctc tactgtggca agctgtactc gcgcaagtat gggctcaaga tccacatgcg
     1981 gacgcacacg ggctacaagc cactcaagtg caaagtctgt ctgcggccct tcggcgaccc
     2041 cagcaatctc aacaagcaca tccggctgca cgccgagggc aatacgccct accgctgcga
     2101 gttctgcggc aaggtacttg tgcgccgccg ggacctggag cgacatgtca agtcccgcca
     2161 ccctggccag agtctgctcg ccaaagcggg cgacggcccg ggtgccgagc ccggctatcc
     2221 cccggagcct ggggatccca agagcgacga cagtgacgtg gacgtctgct tcacagacga
     2281 ccagagcgac cccgaggttg ggggcggcgg ggagcgcgac ttgtaacgag tcttcccggg
     2341 aaggggcggg gtgaggacag agaggagtcg agggtttatt ctcgcagtag aggaactcct
     2401 ggtggtggga agagggaccc aatggacaaa accgtttttg tttttgagag ggcgccagat
     2461 ttgaaacagt gagaggtccc acatctggtg ctgaaactca gagcaacagt tcagaggtgg
     2521 cgtaaatctg gccacctgga gagctcgagt gccaccagta cctccgcacc ccgggcctct
     2581 ggacttcttg gatgagctca ccctgaaccg cccaggcggt ctgctcttgg tgttcagaat
     2641 cacatcaatg cgaacgtcac agcgccttcg agggcgcaga ttttaactgc cacgtatttt
     2701 taagttgtac ttttctgtgg aggaaattgt gccttttgaa acgacgtttt gtgtgtgtat
     2761 ttcacgttag catttcattg cataggcaaa acactagtca caattgggta gatgtgacat
     2821 ccatatactt gtttacattt tatctgttct catgtcaaag actactcctt gccccattga
     2881 atatatagtg gtagcaggtg tacaaattgg tcaagttgca attatttatg agaaaataat
     2941 gataaatgta aaatatctaa agcatgaatc taagagcacg caatatataa ttttaaagaa
     3001 aatattctat ttggtagaat acaaatgtgg tgtgtgttgt tttataatga ctgctgtaca
     3061 gtgggtatag tattttggtt ttggttccag attgtgcaat ctttaagaaa aataaagata
     3121 caaacgaga
//
