LOCUS       NM_001010889            1720 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens PRAME family member 6 (PRAMEF6), mRNA.
ACCESSION   NM_001010889 XM_496345
VERSION     NM_001010889.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1720)
  AUTHORS   Lin,H.C., Ho,S.C., Chen,Y.Y., Khoo,K.H., Hsu,P.H. and Yen,H.C.
  TITLE     SELENOPROTEINS. CRL2 aids elimination of truncated selenoproteins
            produced by failed UGA/Sec decoding
  JOURNAL   Science 349 (6243), 91-95 (2015)
   PUBMED   26138980
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC101342.2 and AL358783.7.
            
            On Mar 8, 2007 this sequence version replaced NM_001010889.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101342.2 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000376189.5/ ENSP00000365360.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                BC101342.2         1-86
            87-329              AL358783.7         28905-29147         c
            330-1720            BC101342.2         330-1720
FEATURES             Location/Qualifiers
     source          1..1720
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..1720
                     /gene="PRAMEF6"
                     /note="PRAME family member 6"
                     /db_xref="GeneID:440561"
                     /db_xref="HGNC:HGNC:30583"
     exon            1..64
                     /gene="PRAMEF6"
                     /inference="alignment:Splign:2.1.0"
     exon            65..373
                     /gene="PRAMEF6"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..1517
                     /gene="PRAMEF6"
                     /codon_start=1
                     /product="PRAME family member 6"
                     /protein_id="NP_001010889.1"
                     /db_xref="CCDS:CCDS30594.1"
                     /db_xref="GeneID:440561"
                     /db_xref="HGNC:HGNC:30583"
                     /translation="MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAF
                     SRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQV
                     LDLQDVCENFWMVWSEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTL
                     DEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVL
                     PILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMN
                     SVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT
                     NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISM
                     ATLENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKR
                     ILFCTDCCPDCGNRSFYDLEADQCCC"
     exon            374..955
                     /gene="PRAMEF6"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1720
                     /gene="PRAMEF6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcctggagt tcctgcttgg ttcttcctga ggactgagca ccttctagac tacatccaga
       61 tctgttttcc ctgcagattc gtgaagatga gcatccggac tccacccaga ctcctggagc
      121 ttgcagggcg gagcctgctg agggaccaag ccttggccat gtccaccctg gaggagctgc
      181 ccacagaact tttcccccca ctgttcatgg aggccttcag caggagacgc tgtgaggccc
      241 tgaagctgat ggtgcaggcc tggcccttcc gccgcctccc tctgaggcct ctgataaaga
      301 tgccttgtct ggaggccttc caagctgtgc tcgatgggct ggatgcactg cttacccaag
      361 gggttcatcc caggaggtgg aaacttcaag tgctggattt acaggatgtc tgtgagaact
      421 tctggatggt ttggtctgaa gctatggccc gtgggtgctt cctcaatgcc aagaggaaca
      481 aaacaccagt gcaggactgt ccaaggatga gaggacagca gcccttgact gtgttcgtag
      541 aactttggct caagaacagg actctggatg aatacctcac ctgcctcctt ctatgggtca
      601 agcagaggaa agatttacta cacctgtgct gtaagaagct gaaaattttg ggaatgccct
      661 tccgcaatat cagaagcatc ctgaaaatgg tgaacctaga ctgtatccag gaggtggaag
      721 tgaattgcaa gtgggtactg cccatcctga cacagtttac cccatacctg ggccacatga
      781 ggaatcttca gaagctcgtt ctctcccaca tggatgtctc tcgctacgtt tccccagagc
      841 agaagaagga gattgttacc cagttcacca ctcagttcct caagctgtgc tgcctccaaa
      901 agctttctat gaactctgtt tctttcctcg aaggccacct ggaccagctg ctcagctgtc
      961 tgaagacctc gttaaaggtc ctcacaataa ctaactgtgt gcttttggaa tcagacttga
     1021 agcatctatc ccagtgcccg agtatcagtc aactaaagac cctggacctg agtggcatca
     1081 gactgaccaa ttacagtctt gtgcctctcc aaattctcct agaaaaagtt gcagccaccc
     1141 ttgagtacct ggatttagat gactgtggca tcatagactc ccaagtcaac gccatcctgc
     1201 ctgccctgag ccgctgcttt gagctcaaca ccttcagctt ctgtggaaat cccatctcca
     1261 tggccaccct ggagaacctg ctgagccaca caatcatact caaaaactta tgcgtggagc
     1321 tgtatcctgc cccccgggag agttatgatg ctgatggtac tctctgctgg agcagatttg
     1381 ctcaaattag ggctgagctg atgaagagag tgagggactt aaggcacccc aagaggatct
     1441 tgttctgtac tgactgctgc cctgactgtg gcaacaggtc attttatgac ctggaggcag
     1501 atcaatgctg ctgttgaatg cctgcctatt tgggtggata tgtcaaacgc tttcttctgg
     1561 acacttggaa actaaaacct aggtcttagg tacatcctat agggagcaca gaacccatca
     1621 tttcacacat gggctctgaa agtgggaaag ggaaggtgat caagcagggg caggacttgg
     1681 gggaagtgtt gccatggatt cgatgggact ttggggacct
//
