LOCUS       NM_001300891            1947 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens PRAME family member 27 (PRAMEF27), mRNA.
ACCESSION   NM_001300891 XM_005276122 XM_006711080
VERSION     NM_001300891.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1947)
  AUTHORS   Hermes,N., Kewitz,S. and Staege,M.S.
  TITLE     Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME
            Family of Leucine-Rich Repeat Proteins
  JOURNAL   Curr Cancer Drug Targets 16 (5), 400-414 (2016)
   PUBMED   26694250
  REMARK    Review article
REFERENCE   2  (bases 1 to 1947)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC245056.3.
            
            On Apr 28, 2020 this sequence version replaced NM_001300891.1.
            
            Sequence Note:.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000436041.6/ ENSP00000393136.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               AC245056.3         140417-140578
            163-471             AC245056.3         143317-143625
            472-1053            AC245056.3         144293-144874
            1054-1947           AC245056.3         146623-147516
FEATURES             Location/Qualifiers
     source          1..1947
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..1947
                     /gene="PRAMEF27"
                     /note="PRAME family member 27"
                     /db_xref="GeneID:101929983"
                     /db_xref="HGNC:HGNC:51234"
     exon            1..162
                     /gene="PRAMEF27"
                     /inference="alignment:Splign:2.1.0"
     exon            163..471
                     /gene="PRAMEF27"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..1615
                     /gene="PRAMEF27"
                     /codon_start=1
                     /product="PRAME family member 27"
                     /protein_id="NP_001287820.1"
                     /db_xref="CCDS:CCDS72704.1"
                     /db_xref="GeneID:101929983"
                     /db_xref="HGNC:HGNC:51234"
                     /translation="MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFME
                     AFSRRCCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVCPRRWKL
                     QVLDLQDVCENFWMVWSEAMARGSFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNR
                     TLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKW
                     VLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY
                     MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIR
                     LTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNAFSFCGNPI
                     SMATLENLLSHTIILKNLCVEVYPAPRESYGADGTLCWNRFAQIRAELMNRVRDLRHP
                     KRIFFCIDNCPDCGNRSFYDLEADQYCC"
     exon            472..1053
                     /gene="PRAMEF27"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1947
                     /gene="PRAMEF27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctagcagt gcacacgtgg aagggcgtgg gtgggagttg tgattagaaa ggtcaataaa
       61 agcttctaaa gacccacagg agagacccaa agtcttcaag cctggagttc ctgcctggtt
      121 cttcctgagg tctgagcacc ttctaaacta catccagatc tgttttccct gcagattcat
      181 gaagatgagc atccggactc cacccagact cctggagctt gcggggcgga gcctgctgag
      241 ggaccaagcc ttggccatgt ccaccctgga ggagctgccc acagaacttt tccccccact
      301 gttcatggag gccttcagca ggagatgctg tgaggccctg aagctgatgg tgcaggcctg
      361 gcccttccgc cgcctccctc tgaggcctct gataaagatg ccttgtctgg aggccttcca
      421 agctgtgctc gatgggcttg atgcactgct tacccaaggg gtttgtccca ggaggtggaa
      481 acttcaagtg ctggatttac aggatgtctg tgagaacttc tggatggttt ggtctgaagc
      541 tatggcccgt gggtccttcc tcaatgccaa gaggaacaaa acaccagtgc aggactgtcc
      601 aaggatgaga ggacagcagc ccttgactgt gttcgtagaa ctttggctca agaacaggac
      661 tctggatgaa tacctcacct acctccttct atgggtcaag cagaggaaag atttactaca
      721 cctgtgctgt aagaagctga aaattttggg aatgcccttc cgcaatatca gaagcatcct
      781 gaaaatggtg aacctagact gtatccagga ggtggaagtg aattgcaagt gggtactgcc
      841 catcctgaca cagtttaccc catacctggg ccacatgagg aatcttcaga agctcgttct
      901 ctctcacatg gatgtctctc gctacgtttc cccagagcag aagaaggaga ttgttaccca
      961 gttcaccact cagttcctca agctgcactg cctccaaaag ctttatatga actctgtttc
     1021 tttcctcgaa ggccacctgg accagctgct cagctgtctg aagacctcgt taaaggtcct
     1081 cacaataact aactgtgtgc ttttggaatc agacttgaag catctatccc agtgcccgag
     1141 tatcagtcaa ctaaagaccc tggacctgag tggcatcaga ctgaccaatt acagtcttgt
     1201 gcctctccaa attctcctag aaaaagttgc agccaccctt gagtacttgg atttagatga
     1261 ctgtggcatc atagactccc aagtcaacgc catcctgcct gccctgagcc gctgctttga
     1321 gctcaatgcc ttcagcttct gtggaaatcc catctccatg gccaccctgg agaacctgct
     1381 gagccacaca atcatactca aaaacttatg cgtggaggtg tatcctgccc cgcgggagag
     1441 ttatggtgct gatggtactc tctgctggaa cagatttgct caaattaggg ctgagctgat
     1501 gaacagagtg agggacttaa ggcaccccaa gaggatcttt ttctgtattg ataactgccc
     1561 tgactgtggc aacaggtcat tttatgacct ggaggcagat caatactgct gttgaatgcc
     1621 tgcctatttg gatgggtatg tcaaacgctt tcttctggac acttggaaac taaaacctag
     1681 gtcttaggta catcctaaag ggagcacaga acccatcatt tcacacatag gctctgaaag
     1741 tgggaaagga aagctgatca agcaggggca ggacttgggg gaaatgttgc catggattcg
     1801 atgggacttt ggggacctgt atcctgtaga gtcgaaaatg ggaatctgaa tgtctagagt
     1861 ggagttcagg cttgagaata catgagggag ttactcttgc atggatggtt gtaaagaaac
     1921 aatcagaaat aaaggaaaac tgagcag
//
