LOCUS       NM_001099852            1597 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens PRAME family member 20 (PRAMEF20), mRNA.
ACCESSION   NM_001099852 NM_001100114 XR_017927
VERSION     NM_001099852.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Birtle,Z., Goodstadt,L. and Ponting,C.
  TITLE     Duplication and positive selection among hominin-specific PRAME
            genes
  JOURNAL   BMC Genomics 6, 120 (2005)
   PUBMED   16159394
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC243961.3.
            
            On or before May 14, 2015 this sequence version replaced
            NM_001100114.1, NM_001099852.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000602960.2/ ENSP00000473584.1
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, expression, longest
                                         protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                AC243961.3         100878-100972       c
            96-386              AC243961.3         94781-95071         c
            387-965             AC243961.3         92722-93300         c
            966-1597            AC243961.3         90094-90725         c
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..1597
                     /gene="PRAMEF20"
                     /gene_synonym="PRAMEF21"
                     /note="PRAME family member 20"
                     /db_xref="GeneID:645425"
                     /db_xref="HGNC:HGNC:25224"
     exon            1..95
                     /gene="PRAMEF20"
                     /gene_synonym="PRAMEF21"
                     /inference="alignment:Splign:2.1.0"
     exon            96..386
                     /gene="PRAMEF20"
                     /gene_synonym="PRAMEF21"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1527
                     /gene="PRAMEF20"
                     /gene_synonym="PRAMEF21"
                     /note="PRAME family member 20/21; PRAME family member 21"
                     /codon_start=1
                     /product="PRAME family member 20"
                     /protein_id="NP_001093322.2"
                     /db_xref="CCDS:CCDS41265.1"
                     /db_xref="GeneID:645425"
                     /db_xref="HGNC:HGNC:25224"
                     /translation="MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAF
                     SRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQV
                     LDLQDVSENFWMVWSEAMARRCLPNAMMNRKPLQDCPRMRGQQPLTVFIDLCLKNRTL
                     DEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTL
                     PVLAEFTPYLGQMRNLRKLVLSDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNS
                     VSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLAN
                     FSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTA
                     TLENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERI
                     LFCTDYCPQCGNRSLYDLEVDRCCC"
     exon            387..965
                     /gene="PRAMEF20"
                     /gene_synonym="PRAMEF21"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1597
                     /gene="PRAMEF20"
                     /gene_synonym="PRAMEF21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acccaaagtc ttcaagcctg gagtttctgc ttggtttttc ctgaggtctg agcaccctgc
       61 aaactgagtc cagatctggt aagtccctaa tctctgaaga tgagcatccg gactccaccc
      121 agactcctgg agctggcggg gcggagcctg ctgagggacg aggccttggc catctccacc
      181 ctggaggagc tgcccacgga actttttccc ccattgttca tggaggcctt cagcaggaga
      241 cactgtgagg ccctgaagct gatggtgcag gcctggcctt tcctccgcct tcctctgggg
      301 tctctgatga aaaggccttg cccagagacc ttccaagctg tgctcgatgg gcttgatgca
      361 ctgcttaccc acagggttcg tctcaggagg tggaaacttc aagtgctgga tttacaggat
      421 gtcagtgaga acttctggat ggtttggtct gaagccatgg cccgtaggtg cttaccaaat
      481 gccatgatga acagaaaacc actgcaggac tgtccaagga tgagaggaca gcagcccttg
      541 actgtgttca tagacctttg cctcaagaac aggactctgg atgaatactt cacctgcctc
      601 tttctatggg tcaagcagag ggaaggttta gtacacctgt gctgtaagaa gctgaaaatg
      661 ttgggaatgc tcttccacaa tatcagaaac atcctgaaaa cagtcaacct agactgtatc
      721 caggaggtgg aagtgaattg caattggaca ctgcccgtcc tggcagagtt taccccatac
      781 ctcggccaga tgaggaatct tcggaagctc gttctctctg acatagattc tcgctacatt
      841 tccccagagc agaagaagga gtttgttacc cagttcacca ctcagttcct caagctgcgc
      901 tgcctccaaa agctttatat gaactctgtt tctttcctcg aaggccacct ggaccagatg
      961 ctcagctgtc taaagacctc gttaaacatc ctcgcaataa ctaactgtgt gcttttggaa
     1021 tcagacttga agcatctgtc caagtacccg agcattggtc aactaaagac cctggacctg
     1081 agtggcacca gactggccaa tttcagcctt gtgccgctcc aagttctcct agaaaaagtt
     1141 gcagccaccc ttgagtacct ggacttagat gactgtggca tcgtagactc ccaagtcaac
     1201 gccatcctgc ctgccctgag ccgctgcttt gagctcacca ccttcagctt ccgtggaaat
     1261 cccatctcca cggccaccct ggagaacctg ctgtgccaca caatcagact caacaactta
     1321 tgcctggagc tgtatcctgc cccgcgggag agttatgatg ttcgtggtat cgtctgccgg
     1381 agcagatttg cccaacttgg ggctgagctg atggggagag tgagggcctt aagggagccc
     1441 gagaggatct tgttctgtac cgactactgc cctcagtgtg gcaacaggtc actttacgac
     1501 ctggaggtag atcggtgttg ctgttgaatg cctgcctatt tgggtggata tatcaaactc
     1561 ttttttctga acacttgaaa actaaaacct aggtctt
//
