LOCUS       NM_023014               1642 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens PRAME family member 2 (PRAMEF2), mRNA.
ACCESSION   NM_023014 XM_938384
VERSION     NM_023014.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Fortna,A., Kim,Y., MacLaren,E., Marshall,K., Hahn,G., Meltesen,L.,
            Brenton,M., Hink,R., Burgers,S., Hernandez-Boussard,T.,
            Karimpour-Fard,A., Glueck,D., McGavran,L., Berry,R., Pollack,J. and
            Sikela,J.M.
  TITLE     Lineage-specific gene duplication and loss in human and great ape
            evolution
  JOURNAL   PLoS Biol 2 (7), E207 (2004)
   PUBMED   15252450
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL049674.1.
            
            On Mar 4, 2006 this sequence version replaced XM_938384.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL049674.1, BC075008.2 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA2145743
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000240189.2/ ENSP00000240189.2
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..1642
                     /gene="PRAMEF2"
                     /gene_synonym="DJ845O24.3"
                     /note="PRAME family member 2"
                     /db_xref="GeneID:65122"
                     /db_xref="HGNC:HGNC:28841"
     exon            1..62
                     /gene="PRAMEF2"
                     /gene_synonym="DJ845O24.3"
                     /inference="alignment:Splign:2.1.0"
     exon            63..374
                     /gene="PRAMEF2"
                     /gene_synonym="DJ845O24.3"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..1512
                     /gene="PRAMEF2"
                     /gene_synonym="DJ845O24.3"
                     /codon_start=1
                     /product="PRAME family member 2"
                     /protein_id="NP_075390.1"
                     /db_xref="CCDS:CCDS149.1"
                     /db_xref="GeneID:65122"
                     /db_xref="HGNC:HGNC:28841"
                     /translation="MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAF
                     SRRHFQTLTVMVQAWPFTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQV
                     LDLRDVDENFWARWPGAWALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQ
                     DECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWP
                     HLIRKLYCYLKEMKTLCKLVFSRCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKL
                     ITFFSGHLEQLIRCLQNPLENLELTCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFR
                     ISLEPLGALLEKIAASLETLVLEGCQIHYSQLSAILPGLSCCSQLTTFYFGSNCMSID
                     ALKDLLRHTSGLSKLSLETYPAPEESLNSLVRVNWEIFTPLRAELMCTLREFRQPKRI
                     FIGPTPCPSCGSSPSEELELHLCC"
     exon            375..953
                     /gene="PRAMEF2"
                     /gene_synonym="DJ845O24.3"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1642
                     /gene="PRAMEF2"
                     /gene_synonym="DJ845O24.3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgaagcta ctggttggtt ccctgagagg tcccagaact ctgcaaagtg agtccagcgc
       61 tgagattttt cttgcagatc catcaggatg agcatccagg ccccaccgag actactggag
      121 ctggcggggc agagcctgct gagagaccag gccttgtcca tctctgccat ggaggagctg
      181 cccagggtgc tctatctccc actcttcagg gaggccttca gcaggagaca cttccagact
      241 ctgacggtga tggtgcaggc ctggcctttc acctgcctcc ctctggtatc gctgatgaag
      301 acgcttcatc tggagccatt gaaagcattg ctggaagggc ttcatatgct gcttacacag
      361 aaggatcgcc ccaggaggtg gaaacttcaa gtgctggatt tgcgggatgt tgatgagaat
      421 ttctgggcca gatggcctgg agcctgggcc ctgtcctgct tcccagaggc catgagtaag
      481 aggcagacag cagaggactg tccaaggacg ggagagcacc agcccttaaa ggtgttcata
      541 gacatctgcc tcaaggaaat accccaggat gaatgcctga gatacctctt ccagtgggtt
      601 taccaaagga gaggtttagt acacctgtgc tgtagtaagc tggtcaatta tctaacgcca
      661 attaaatatc tcagaaagtc attgaaaata atatacatta atagtattgg ggagctggaa
      721 attcacaaca cgtgctggcc acatctgata agaaagcttt attgttacct gaaggagatg
      781 aagactcttt gcaaactcgt tttctccagg tgccatcatt acacgtcaga taatgaactc
      841 gagggatggt tagtcaccag attcacctct gtgttcctca ggctggaaca cctccagttg
      901 cttaaaataa aattgatcac cttcttcagt gggcacctgg aacagctgat caggtgcctc
      961 cagaacccct tggagaactt ggaattaact tgtggcaacc tattagaaga ggacttgaag
     1021 tgtctctccc agttcccaag cctcggttac ctaaagcatc tgaatctcag ctacgtgctg
     1081 ctgttccgca tcagtcttga acccctagga gctctgctag agaaaattgc tgcctctctc
     1141 gagaccctcg tgttagaggg ctgtcagatc cactactccc aactcagtgc catcctgcct
     1201 ggcctgagct gctgctccca gctcaccacc ttctactttg gcagcaattg catgtctatt
     1261 gacgccctga aggacctgct gcgccacacc agtgggctga gcaagttaag cctggagacg
     1321 tatcctgccc ctgaggagag tttgaattcc ttggttcgtg tcaattggga gatcttcacc
     1381 ccacttcggg ctgagctgat gtgtacactg agggaattca ggcagcccaa gaggatcttc
     1441 attggcccca ccccctgccc ttcctgtggc tcatcaccgt ctgaggaact ggagctccat
     1501 ctttgctgct agggaaggcg tgcccagtgg ggtagagaaa tccaaagttc tcttccaggc
     1561 acttggacac taaaatctac tatgtaggtg caaactattt ttctcttttc ttatttattt
     1621 cattttttaa taattccaaa at
//
