LOCUS       NM_001099790            2123 bp    mRNA    linear   PRI 05-JUN-2024
DEFINITION  Homo sapiens PRAME family member 19 (PRAMEF19), mRNA.
ACCESSION   NM_001099790 XM_001130249
VERSION     NM_001099790.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2123)
  AUTHORS   Chang,T.C., Yang,Y., Yasue,H., Bharti,A.K., Retzel,E.F. and
            Liu,W.S.
  TITLE     The expansion of the PRAME gene family in Eutheria
  JOURNAL   PLoS One 6 (2), e16867 (2011)
   PUBMED   21347312
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2123)
  AUTHORS   Birtle,Z., Goodstadt,L. and Ponting,C.
  TITLE     Duplication and positive selection among hominin-specific PRAME
            genes
  JOURNAL   BMC Genomics 6, 120 (2005)
   PUBMED   16159394
  REMARK    Publication Status: Online-Only
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AC243961.3.
            
            On Sep 9, 2021 this sequence version replaced NM_001099790.4.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000376101.4/ ENSP00000365269.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-334               AC243961.3         139475-139808
            335-913             AC243961.3         140195-140773
            914-2123            AC243961.3         141782-142991
FEATURES             Location/Qualifiers
     source          1..2123
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..2123
                     /gene="PRAMEF19"
                     /note="PRAME family member 19"
                     /db_xref="GeneID:645414"
                     /db_xref="HGNC:HGNC:24908"
     exon            1..334
                     /gene="PRAMEF19"
                     /inference="alignment:Splign:2.1.0"
     CDS             48..1487
                     /gene="PRAMEF19"
                     /note="PRAME family member-like"
                     /codon_start=1
                     /product="PRAME family member 19"
                     /protein_id="NP_001093260.3"
                     /db_xref="CCDS:CCDS41263.1"
                     /db_xref="GeneID:645414"
                     /db_xref="HGNC:HGNC:24908"
                     /translation="MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAF
                     TSRCCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQV
                     LEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSV
                     DEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWP
                     CMVAEVSRYLSQMKNLRKLFISDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRR
                     IRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRF
                     IRLEPLRALLEKVAATLQTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMD
                     GLKDLLRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRI
                     FFGPVSCPCCGMSPTEQLEFNFCLRGRPA"
     exon            335..913
                     /gene="PRAMEF19"
                     /inference="alignment:Splign:2.1.0"
     exon            914..2123
                     /gene="PRAMEF19"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2094..2099
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PRAMEF19"
                     /note="hexamer: AATAAA"
     polyA_site      2113
                     /gene="PRAMEF19"
                     /note="major polyA site"
ORIGIN      
        1 ctgataagtt tgtcttttct ctggattttt cttgcagatt tatcaggatg agcttccagg
       61 ccccacgcag actcctggag ctggcagggc agagcctgct gagggaccag gccttggcca
      121 tctccgtcct ggatgagctg cccagggagc tcttcccccg actgttcgtg gaggccttca
      181 ctagcagatg ctgcgaggtt ctgaaggtga tggtgcaggc ctggcccttc ccctgcctcc
      241 ctctggggtc cctgatgaag acgcctgatc tggagatctt acattatgta gtggatggga
      301 ttgattgcct gcttgcccaa aaggttcgcc ccaggaggtg gaaacttcaa gtgctggaaa
      361 tgcgggatgt tgatgagaat ttttggacca tatggtctgg agccaggccc ctgtcctgct
      421 ccccagaggc catgagtaag agacagacag tggaggactg tccaaggaca ggagagaagc
      481 agcccttgaa ggtgttcatg gatgtttgcc tcaaggaaaa atccgtggat gaagatctga
      541 gcttcttctc tgggtgggtg cagcacagaa gacgttcagt acacctgtgc tgtactaagg
      601 tggtaaatta ttcaatgaac attctaaatt tcagaaacat attagaaaca gtatacccag
      661 acagtatcca agtattggaa atttggaaca tgtgctggcc gtgtatggta gcagaggtta
      721 gccgttacct gagccagatg aagaatcttc gaaaactctt catctccgat ggctgtggtt
      781 acctgccaag ctttgagagc caaggacagt tagttgctga attcagctct gtgttcctca
      841 ggctggagta cctccagatg ctttatatga gaaggatccg cttcttcgaa ggctacctgg
      901 accagctgat caggtgcctc aagagcccgt tggagacatt ggcattaact tatggctccc
      961 tagatgaaga ggacttgaaa tgtctgccct ggtacccaag tctcagtcaa ctgaagcagc
     1021 tgaatctgag tcatggtaca ctgcgcttca tccgtcttga gcccctccga gctctgctag
     1081 agaaagttgc tgccactctt cagaccctct tcttagtgga ctgtgggatt ggggactcca
     1141 aactcagggt catcctgcct gccctgagcc gctgctccaa cctcaccact ttctgctttc
     1201 acggcaatga cacgtccatg gatggtctga aggacctgct gcgccacaca ggcaggctga
     1261 gcaatttgag cctggaaaca tatcctgccc ctcgggagag tcttgacaac aggggtcgtg
     1321 tcatttcgga gctcctcacc ccacttcagg ctgagctgat gcgtatactg agggaagtaa
     1381 gggagcccaa caggatcttc tttggtcccg tctcctgccc ttgctgtggc atgtcaccca
     1441 ctgagcaact ggagttcaat ttttgcttgc ggggaaggcc tgcctagtgg ggtggaggta
     1501 taaaaagctt tttctccagg cacttggaaa ctaaaatcta ggacatagat atcttttatt
     1561 tttctttttc cttattttac aattttacag cttttattta aaaatttgag acagggtttc
     1621 cctatgttgt ccaggctggt ctcaaactct tacgcttaag ggagccccct gcttggcctc
     1681 ccaagattct gggattacag gcataagcag ctgtgccggg tctataggtg tattataaag
     1741 ggagcagaga aacctctgtt tcaggcatgt gctttctgtg agtgggaaaa aaaacacaaa
     1801 aaaacccagc agggggcagc actggggaaa aggttgaatg gagtcactga gactcaggga
     1861 tctgtgtcct agacagtcag aaatagaacc tgaagttcta gagtgaagga gttatctcag
     1921 caaggatgga tacaaagaaa cgtcggaagt aaagggaacc taaatggaaa ctctctgctg
     1981 tccttcatga ttgattagcc tgtttcagca atttatacat cagaaatctt tagttcctga
     2041 tgaattaaaa aaagaggtac tagttcatct gtgatttaag ttcatccgca ggaaataaag
     2101 gaatcaaaat aaacttcatt ttg
//
