LOCUS       NM_001099850            2125 bp    mRNA    linear   PRI 05-JUN-2024
DEFINITION  Homo sapiens PRAME family member 18 (PRAMEF18), mRNA.
ACCESSION   NM_001099850 NM_001291370
VERSION     NM_001099850.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2125)
  AUTHORS   Chang,T.C., Yang,Y., Yasue,H., Bharti,A.K., Retzel,E.F. and
            Liu,W.S.
  TITLE     The expansion of the PRAME gene family in Eutheria
  JOURNAL   PLoS One 6 (2), e16867 (2011)
   PUBMED   21347312
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2125)
  AUTHORS   Birtle,Z., Goodstadt,L. and Ponting,C.
  TITLE     Duplication and positive selection among hominin-specific PRAME
            genes
  JOURNAL   BMC Genomics 6, 120 (2005)
   PUBMED   16159394
  REMARK    Publication Status: Online-Only
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AC244216.2.
            
            On or before Apr 15, 2014 this sequence version replaced
            NM_001291370.1, NM_001099850.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000624297.3/ ENSP00000485473.2
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-335               AC244216.2         86650-86984
            336-914             AC244216.2         87371-87949
            915-2125            AC244216.2         88899-90109
FEATURES             Location/Qualifiers
     source          1..2125
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.21"
     gene            1..2125
                     /gene="PRAMEF18"
                     /note="PRAME family member 18"
                     /db_xref="GeneID:391003"
                     /db_xref="HGNC:HGNC:30693"
     exon            1..335
                     /gene="PRAMEF18"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1488
                     /gene="PRAMEF18"
                     /note="PRAME family member-like"
                     /codon_start=1
                     /product="PRAME family member 18"
                     /protein_id="NP_001093320.2"
                     /db_xref="CCDS:CCDS41258.2"
                     /db_xref="GeneID:391003"
                     /db_xref="HGNC:HGNC:30693"
                     /translation="MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPPLFVEAF
                     TSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQV
                     LEMRDVDENFWTIWSGARLLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFM
                     DEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWL
                     CMIVEFSRYLSQMRNLRKLFISDGCRYLLSSDSQEQLVAEFSSVLLRLENLQMLYVRR
                     VCFFRGHLDQLIRCLRSPLETLALTYGFLEEEDLKCLPRYPSLSQLKQLNLSHGALRF
                     IRLEPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMD
                     ALKDLLRHTGRLSNLSLETYPAPRESLDNRGRVILELLTPLQAELMRILREVREPKRI
                     FFGPVSCPCCGTSPTEQLESNFCLWGRPA"
     exon            336..914
                     /gene="PRAMEF18"
                     /inference="alignment:Splign:2.1.0"
     exon            915..2125
                     /gene="PRAMEF18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgataagtt tgtcttctct ggatttgttt tcttgcagat ttatcaggat gagcttccag
       61 gccccacgca gactcctgga gctggcaggg cagagcctgc tgagggacca ggccttggcc
      121 atctccgtcc tggatgagct gcccagggag ctcttccccc cactgttcgt ggaggccttc
      181 actagcagac gctgcgaggt tctgaaggtg atggtgcagg cctggccctt cccctgcctc
      241 cctctggggt ccctgatgaa gacgcctgat ctggagatct tacattatgt agtggatggg
      301 attgattgcc tgcttgccca aaaggttcgc cccaggaggt ggaaacttca agtgctggaa
      361 atgcgggatg ttgatgagaa tttttggacc atatggtctg gagccaggct cctgtcctgc
      421 tccccagagg ccatgagtaa gagacagaca gtggaggact gtccaaggac aggagagaag
      481 cagcccttga aggtgttcat ggatgtttgc ctcaaggaaa aattcatgga tgaagatctg
      541 agcttcttct ctgggtgggt gcagcacaga agaggttcag tacacctgtg ctgtactaag
      601 gtggtgaatt attcaatgag cattctaaat ttcagaaaca tattggaaac agtataccca
      661 gacagtatcc aagtgttgga aatttggaac atgtgctggc tgtgtatgat agtagagttt
      721 agccgttacc tgagccagat gaggaatctt cgcaaactct tcatctctga tggctgtcgt
      781 tacctgctaa gctctgacag ccaagaacag ttagttgctg aattcagctc tgtgctcctc
      841 aggctggaga acctccagat gctttatgta agaagggtct gcttcttcag aggccacctg
      901 gaccagctga tcaggtgcct caggagcccg ttggagacat tggcattaac ttatggcttc
      961 ctagaagaag aggacttgaa atgcctgccc cggtacccaa gtctcagtca actgaagcag
     1021 ctgaatctga gtcatggtgc actgcgcttc atccgtcttg agcccctccg agctctgcta
     1081 gagaaagttg ctgccactct tcagaccctc ttcttagtgg actgtgggat tgggtactcc
     1141 aaactcaggg tcatcctgcc tgccctgagc cgctgctcca acctcaccac tttctgtttt
     1201 cacggcaatg acacgtccat ggatgctctg aaggacctgc tgcgccacac aggcaggctg
     1261 agcaatttga gcctggaaac atatcctgcc cctcgggaga gtcttgacaa caggggtcgt
     1321 gtcattttgg agctcctcac cccacttcag gctgagctga tgcgtatact gagggaagta
     1381 agggagccca aaaggatctt ctttggtccg gtgtcctgcc cttgctgtgg cacgtcgccc
     1441 actgagcaac tggagtccaa tttttgcttg tggggaaggc ctgcctagtg gggtggaggt
     1501 ataaaaagct ttttctccag gcacttggaa actaaaatct gggacataga tgtcttttat
     1561 ttttcttttt ccttatttta caattttaca gcttttattt aaaaatttga aacagggttt
     1621 ccctatgttg tccaggctgg tctcaaactc ttacgcttaa gggagccccc tgcttggcct
     1681 cccaagattc tgggattaca ggcataagca gctgtgccgg gtctataggt gtattataaa
     1741 gggaacagag aaacctctgt ttcaggcatg tgctttctgt gagtggaaaa caaaaaacaa
     1801 aaaatcccag cagggggcag cactggggaa aaagttgaat ggagtcactg agactcaggg
     1861 atctgtgtcc tagacagtca gaaatagaaa gctgaagttc tagagtgagg gagttatctc
     1921 agcaaggatg gatacaaaga aacgtcggaa gtagagggaa cctaaatgga aactctctgc
     1981 tgtccttcat gattgattag cctgtttcag caatttatac atcagaaatc tttagttcct
     2041 gatgaattaa aaaaagaggt actagttcat ctgtgattta ggttcatctg caggaaataa
     2101 aggaatcaaa ataaacttca tgttg
//
