LOCUS       NM_172365               1349 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens protein phosphatase 1 regulatory subunit 36 (PPP1R36),
            mRNA.
ACCESSION   NM_172365
VERSION     NM_172365.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Hendrickx,A., Beullens,M., Ceulemans,H., Den Abt,T., Van Eynde,A.,
            Nicolaescu,E., Lesage,B. and Bollen,M.
  TITLE     Docking motif-guided mapping of the interactome of protein
            phosphatase-1
  JOURNAL   Chem Biol 16 (4), 365-371 (2009)
   PUBMED   19389623
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC068989.1 and AL049869.6.
            
            On Nov 22, 2018 this sequence version replaced NM_172365.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.130813.1,
                                           SRR1803612.155454.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000298705.6/ ENSP00000298705.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-23                BC068989.1         25-47
            24-24               AL049869.6         129899-129899       c
            25-284              BC068989.1         49-308
            285-285             AL049869.6         115067-115067       c
            286-1347            BC068989.1         310-1371
            1348-1349           AL049869.6         90502-90503         c
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q23.3"
     gene            1..1349
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /note="protein phosphatase 1 regulatory subunit 36"
                     /db_xref="GeneID:145376"
                     /db_xref="HGNC:HGNC:20097"
                     /db_xref="MIM:619923"
     exon            1..106
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1306
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /codon_start=1
                     /product="protein phosphatase 1 regulatory subunit 36"
                     /protein_id="NP_758953.1"
                     /db_xref="CCDS:CCDS9767.1"
                     /db_xref="GeneID:145376"
                     /db_xref="HGNC:HGNC:20097"
                     /db_xref="MIM:619923"
                     /translation="MYRVPEFYARRKRLGGQTPYLMDQLGLRLGMWYWKDETRTLEFR
                     RFAAEDSVQWLLKHHPHFTPAAEVKEKGKKGKAVHFAETDGPASDRLTDKRLAAKDDK
                     SAKAVEKRGQQGTITLDDVKFVTLLLLQDTEMQRICSFTTFMRNKNLDNFLMALLYYL
                     SHYLEKNSLEKKPKSYMVGLVEKKEMELVLSELEAAQRYLAQKYCILVLGLAVPDKHH
                     MCCGKEKISDTQKDWKFFESFYTFCTYVAWIVFRRQHLTEIEEEVGRLFRTNMFNIPR
                     RRREDEESGGEKKRMTFVQFRRMMAKRPAIKKAINMRSPVMSTLLPSLREKAQNVFEK
                     KYHQVDVRFPAEMQKHVGTLDSVPMPVVGILGEPRCLFNPHTLHPLDPEENTKSFGRY
                     PSLMENNNMRIQDTLDLVMKTLSSHTSCPK"
     exon            107..171
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            172..219
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            220..306
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            307..404
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            405..471
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            472..570
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            571..705
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            706..748
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            749..927
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1119
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1349
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1328..1333
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /note="hexamer: AGTAAA"
     polyA_site      1349
                     /gene="PPP1R36"
                     /gene_synonym="C14orf50"
                     /note="major polyA site"
ORIGIN      
        1 atcctcggcg acgccgtatg gcttccaggg cgaggccatg taccgggtgc ccgagtttta
       61 tgcgaggagg aagcggttag gtgggcagac cccttacttg atggatcagt tgggattacg
      121 attagggatg tggtactgga aagatgaaac cagaactctt gaattcagaa ggtttgccgc
      181 agaagattct gtccagtggc tcctgaaaca tcaccctcat tttacacctg cagcagaagt
      241 caaggaaaaa ggaaagaaag gcaaagcagt tcactttgca gaaactgatg gtccagcttc
      301 agacaggttg acagataaaa gacttgctgc aaaagatgat aagtcagcta aagctgtaga
      361 gaaacgaggt caacagggca ccattacact ggatgatgtt aaatttgtta ctttgctttt
      421 gctacaagat actgagatgc agcggatctg ttcttttaca acatttatga ggaataagaa
      481 tcttgataat ttcctcatgg cattattgta ctacttatcc cattacttgg aaaaaaactc
      541 actggaaaag aaacccaaaa gctatatggt aggccttgta gagaaaaaag aaatggaatt
      601 ggttttaagt gaattagaag cagcacagag gtacttggcg cagaagtact gtatccttgt
      661 gctgggcttg gccgtgccgg ataagcatca catgtgctgt ggaaaggaga aaatatcaga
      721 tacacagaaa gactggaagt tctttgagtc cttttatact ttctgtacat atgtggcttg
      781 gattgtcttc cgacgtcaac acttgacaga gattgaagaa gaagtaggga gactctttcg
      841 taccaatatg ttcaacattc ctcgcaggag gcgtgaagat gaggaatcag gaggggaaaa
      901 gaaacgcatg acttttgttc agttcaggag aatgatggca aaacgcccag caattaaaaa
      961 agctatcaac atgcgttctc cagtcatgtc tactctgctg ccatctctca gagaaaaagc
     1021 tcaaaacgtc tttgagaaaa agtatcatca agtagacgtc agattcccag ccgagatgca
     1081 aaagcatgtg ggaactctgg actctgtgcc catgccggta gttggcatct tgggggagcc
     1141 tcgatgtcta ttcaacccac atacgcttca cccccttgat ccagaagaaa acacaaaatc
     1201 atttgggaga tatccttcct tgatggaaaa caataacatg aggattcagg atacactgga
     1261 cttggtcatg aaaacactgt cctctcatac atcatgccct aagtaacctg gtacattcca
     1321 tatctcaagt aaactacttt gactttata
//
