LOCUS       NM_004792               6357 bp    mRNA    linear   PRI 09-FEB-2025
DEFINITION  Homo sapiens peptidylprolyl isomerase G (PPIG), mRNA.
ACCESSION   NM_004792
VERSION     NM_004792.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6357)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 6357)
  AUTHORS   Szlavicz,E., Szabo,K., Groma,G., Bata-Csorgo,Z., Pagani,F.,
            Kemeny,L. and Szell,M.
  TITLE     Splicing factors differentially expressed in psoriasis alter mRNA
            maturation of disease-associated EDA+ fibronectin
  JOURNAL   Mol Cell Biochem 436 (1-2), 189-199 (2017)
   PUBMED   28589370
  REMARK    GeneRIF: results indicate that LUC7L3, PPIG, and SFRS18 are not
            only implicated in EDA+ fibronectin formation, but also that they
            could possess multiple roles in psoriasis-associated molecular
            abnormalities.
            Erratum:[Mol Cell Biochem. 2017 Dec;436(1-2):201. doi:
            10.1007/s11010-017-3105-y.. PMID: 28770468]
REFERENCE   3  (bases 1 to 6357)
  AUTHORS   Nakamura,K., Aizawa,K., Aung,K.H., Yamauchi,J. and Tanoue,A.
  TITLE     Zebularine upregulates expression of CYP genes through inhibition
            of DNMT1 and PKR in HepG2 cells
  JOURNAL   Sci Rep 7, 41093 (2017)
   PUBMED   28112215
  REMARK    GeneRIF: The finding that zebularine upregulates CYP gene
            expression through DNMT1 and PKR modulation sheds light on the
            mechanisms controlling hepatocyte function and thus may aid in the
            development of new in-vitro systems using high-functioning
            hepatocytes
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6357)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 6357)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 6357)
  AUTHORS   Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
            Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
            Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
  TITLE     Proteomic, functional, and domain-based analysis of in vivo 14-3-3
            binding proteins involved in cytoskeletal regulation and cellular
            organization
  JOURNAL   Curr Biol 14 (16), 1436-1450 (2004)
   PUBMED   15324660
REFERENCE   7  (bases 1 to 6357)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   8  (bases 1 to 6357)
  AUTHORS   Dubourg,B., Kamphausen,T., Weiwad,M., Jahreis,G., Feunteun,J.,
            Fischer,G. and Modjtahedi,N.
  TITLE     The human nuclear SRcyp is a cell cycle-regulated cyclophilin
  JOURNAL   J Biol Chem 279 (21), 22322-22330 (2004)
   PUBMED   15016823
  REMARK    GeneRIF: human nuclear SRcyp is a cell cycle-regulated cyclophilin
REFERENCE   9  (bases 1 to 6357)
  AUTHORS   Bourquin,J.P., Stagljar,I., Meier,P., Moosmann,P., Silke,J.,
            Baechi,T., Georgiev,O. and Schaffner,W.
  TITLE     A serine/arginine-rich nuclear matrix cyclophilin interacts with
            the C-terminal domain of RNA polymerase II
  JOURNAL   Nucleic Acids Res 25 (11), 2055-2061 (1997)
   PUBMED   9153302
REFERENCE   10 (bases 1 to 6357)
  AUTHORS   Nestel,F.P., Colwill,K., Harper,S., Pawson,T. and Anderson,S.K.
  TITLE     RS cyclophilins: identification of an NK-TR1-related cyclophilin
  JOURNAL   Gene 180 (1-2), 151-155 (1996)
   PUBMED   8973360
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG615922.1, X99717.1, CA418130.1 and AC016772.9.
            
            On Nov 22, 2018 this sequence version replaced NM_004792.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.83671.1,
                                           SRR1803617.72391.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000260970.8/ ENSP00000260970.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               BG615922.1         13-176
            165-2303            X99717.1           113-2251
            2304-2695           CA418130.1         12-403              c
            2696-6357           AC016772.9         60614-64275         c
FEATURES             Location/Qualifiers
     source          1..6357
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q31.1"
     gene            1..6357
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /note="peptidylprolyl isomerase G"
                     /db_xref="GeneID:9360"
                     /db_xref="HGNC:HGNC:14650"
                     /db_xref="MIM:606093"
     exon            1..140
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            141..193
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            194..270
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     CDS             210..2474
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /EC_number="5.2.1.8"
                     /note="Clk-associating RS-cyclophilin; peptidyl-prolyl
                     isomerase G (cyclophilin G); SR-related CTD-associated
                     factor 10; CASP10; SR-cyp; PPIase G; rotamase G;
                     SR-cyclophilin; CARS-cyclophilin"
                     /codon_start=1
                     /product="peptidyl-prolyl cis-trans isomerase G"
                     /protein_id="NP_004783.2"
                     /db_xref="CCDS:CCDS2235.1"
                     /db_xref="GeneID:9360"
                     /db_xref="HGNC:HGNC:14650"
                     /db_xref="MIM:606093"
                     /translation="MGIKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLC
                     TGEKGTGKSTQKPLHYKSCLFHRVVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAV
                     KHNKEFLLSMANRGKDTNGSQFFITTKPTPHLDGHHVVFGQVISGQEVVREIENQKTD
                     AASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSD
                     SESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEE
                     IPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIK
                     GRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIK
                     ENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKN
                     KVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG
                     KDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERS
                     RSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRR
                     RRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKA
                     DRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKF
                     DHESSPGTDEDKSG"
     exon            271..345
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            346..453
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            454..498
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            499..586
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            587..616
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            617..756
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            757..970
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1138
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1226
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1363
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..6357
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2672..2677
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /note="hexamer: AATAAA"
     polyA_site      2695
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /note="major polyA site"
     regulatory      6337..6342
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
                     /note="hexamer: AATAAA"
     polyA_site      6357
                     /gene="PPIG"
                     /gene_synonym="CARS-Cyp; CYP; SCAF10; SRCyp"
ORIGIN      
        1 gcgacgctgt ctctccatgc caggactgag ttgtggggga gggaggcggt tagcgggctt
       61 tagcgccttt tctggcggcg gtagatttga agcgcttcaa aggaccggac ccagagaaga
      121 ggaaaactct accggtgcag gagcacaggg atcagttgtc cttgtttttt tttggtcttt
      181 tcttcatttg aagattaagt attggagcca tgggaataaa ggttcaacgt cctcgatgtt
      241 tttttgacat tgccattaac aatcaacctg ctggaagagt tgtctttgaa ttattttctg
      301 atgtgtgccc caaaacatgc gagaactttc gttgtctttg tacaggtgaa aaggggaccg
      361 ggaaatcaac tcagaaacca ttacattata agagttgtct ctttcacaga gttgtcaagg
      421 attttatggt tcaaggtggt gacttcagtg aaggaaatgg acgaggaggg gaatctatct
      481 atggaggatt ttttgaagac gagagtttcg ctgttaaaca caacaaagaa tttctcttgt
      541 caatggccaa cagagggaag gatacaaatg gttcacagtt cttcataaca acgaaaccaa
      601 ctcctcattt agatgggcat catgttgttt ttggacaagt aatctctggt caagaagttg
      661 taagagagat tgaaaaccag aaaacagatg cagctagcaa accgtttgcg gaggtacgga
      721 tactcagttg tggagagctg attcccaaat ctaaagttaa gaaagaagaa aagaaaaggc
      781 ataaatcatc atcatcttcc tcctcctcat ctagtgactc agatagctca agtgattctc
      841 agtcctcttc tgattcctct gattccgaaa gtgctactga agagaaatca aagaaaagaa
      901 aaaagaaaca tcggaaaaat tcccgaaaac acaagaaaga aaagaaaaag cgaaagaaaa
      961 gcaagaagag tgcatctagt gagagtgaag ctgaaaatct tgaagcacaa ccccagtcta
     1021 ctgtccgtcc agaagagatc cctcctatac ctgaaaatag attcctaatg agaaaaagtc
     1081 ctcctaaagc tgatgagaag gaaaggaaaa acagagagag agaaagggaa agagagtgta
     1141 atccacctaa ctcccagcct gcttcatacc agagacgact tttagttact agatctggca
     1201 ggaaaattaa aggaagagga ccaaggcgtt atcgaactcc ttccagatcc agatcaaggg
     1261 atcgtttcag acgtagtgag actcctccac attggaggca agagatgcag agagctcaaa
     1321 gaatgagggt atcaagtggt gaaagatgga tcaaggggga taagagtgag ttgaatgaaa
     1381 taaaagaaaa tcagagaagt ccagttagag taaaagagag aaaaataaca gatcacagga
     1441 atgtatctga gagtccaaac agaaaaaatg aaaaggagaa gaaagttaaa gaccataaat
     1501 ctaacagcaa agagagagac atcagaagaa attcagaaaa agatgacaag tataaaaaca
     1561 aagtgaagaa aagggccaaa tctaaaagta ggagtaagag caaagagaaa tcaaagagta
     1621 aagaaagaga ttcaaaacat aatagaaatg aagaaaagag gatgaggtca aggagtaaag
     1681 gaagggatca tgaaaatgtt aaagaaaaag aaaagcagtc tgattctaaa ggaaaagatc
     1741 aggaaaggag tagaagtaaa gagaagtcta aacagttaga atcaaagagt aatgagcatg
     1801 atcacagtaa aagtaaggaa aaggatagac gcgcacaatc caggagtaga gaatgtgata
     1861 taactaaagg taaacacagt tataatagca gaacaagaga acgaagcaga agtagggaca
     1921 gaagcagaag agtgcgatca agaacccatg acagagatcg cagcagaagc aaggagtacc
     1981 atagatacag agaacaggaa tacaggagaa gaggacggtc acgaagccga gagagaagaa
     2041 caccaccagg aagatcaaga agtaaagata ggaggagaag gaggagagac tcacggagct
     2101 cagagagaga agaaagtcaa agcagaaaca aagacaaata cagaaaccaa gagagtaaga
     2161 gctcacacag aaaagaaaat tctgagagtg agaaaagaat gtactctaaa agtcgtgatc
     2221 ataatagctc aaataacagc agggaaaaaa aggctgatag agatcaaagt cccttctcaa
     2281 aaataaaaca aagcagtcag gacaatgaat taaagtcctc catgttgaaa aataaggagg
     2341 atgagaagat cagatcctca gtggaaaaag aaaaccaaaa atcaaaaggt caagaaaatg
     2401 accatgtaca tgaaaaaaat aaaaaatttg atcatgaatc aagccctgga acagatgaag
     2461 acaaaagcgg atgagtgagt tatataaact tacttccatt ctgtttcgga ttttaagttt
     2521 gagagacttg ctaatgaatc tcctttatgt tgttttcctt ttcattgttt ttggattgtt
     2581 ttatgtttgt cctttttttt cttaatgtgg atttcattga gttgattttt tgataatctg
     2641 caatctggat aatttgtact gctaaagttt taataaactc gacatgagaa aaacactttg
     2701 gtgtagtact gtgtgctgtg tttaactatt ttatgtatgc attactgtgt tgcaacaatt
     2761 agccaatagc atcctaattt gtttagtcag ccatttggaa tggttgcaat gcattgttgc
     2821 aaaagcttgt gtttctcatg attaaagtaa ctttagaagc cactagaaga catcttgtat
     2881 agattttctg attgcgttat aaatagaggt ttgcagcggt ttcttttaat tacacagaag
     2941 cagggtccta ataacctgag atcttaaatc atcacttttg attttatagt aatttgtgct
     3001 ttaaaataga tgtatttata ttgcacttca tactctattc tttatagttc gagccatagc
     3061 ttgtttccta ttaatgcttt tcctgtctag ttgtgtttta cttaactgcc tataaaaatc
     3121 gtaagagtaa tttttttcag ttgatgtact gattgagctt gagttgctgt tatacagcat
     3181 ttgacaggaa ctataccttg gaaaatcaga ttgtgattct cagttctgtg ttgcttttgg
     3241 tttgaagagt tttgggaacg ttttaattat taattaccct tctctaaact ttaaaaaaaa
     3301 aaaagctttt ctcattaaaa cataccattt gtgcaggtcc ttaagctata cagattctaa
     3361 aaattgttag tattgagaca ttaacttcta agatttctct tttttggcct ccaacctata
     3421 tagaattgag tgttaactct gcatggattt tgtttgtttt aattgaactg acttctctaa
     3481 ctctcatagc tgtgagttcc aaatggcaag aaaatgcatc ttttctatat atgtatcacg
     3541 ataggctata gcatgtttat gactctggtt tctttctctt caggtggttt tataccatta
     3601 ctgttaatgt tattttaact tggcatgtat aacattgcca tatagagtag agtagaaagt
     3661 tgcaaatttt gatagtttac agagttaaac actaaacata tccaaagtcc atttagagtt
     3721 ttgggtgttg tattttgcca tttttgtgat gtgtggcctt ttattctgta atctcttcta
     3781 aataaaacat tgaacatcca gcaaacataa aacctgcctc atttgaaaag gaatttcaaa
     3841 attccaatta ataggattct ctagagagtt ttgtacttta atatttgtca gtgtagtgtc
     3901 aactctgtta ccaaggtagc ttcttggtaa atccagtagc tactcaatgc tatttgtact
     3961 gaataaagca attattaaca tgatacttcc cactattgat taatgcaata ttgatatatt
     4021 tggcgttgtg gtagctgttg cagaatgaat agtgtaatga ccataagatt gcttggaaaa
     4081 ttgtaataca gatatccaca atgaattctt tccaaaattt ttttttccga tgataaaagt
     4141 agtagatgtt tattataaaa tccaaggtga ttgattcctt agagactgac cacaaaccca
     4201 cattagggat aattgagtct gagtgcccaa gctatataac gttatgtagt ttaagcaagt
     4261 tattgtttgt cttaatttca gttaactgca ttttaaaatt gttgttataa actatttgag
     4321 ctttaagaaa ggtgctattt aagaaaggat ttctaataac agttaaatat tttttttaag
     4381 tccatgctaa gtaaaaattc ttacatgttg tctgatccca gagctttatc tactaaaaat
     4441 tatacataag gatttccaaa tcttagagtt tcaaaaagta accataggga aaaaaattgt
     4501 agtaatttct ataggcaata ttctgtttgg gttatcaaaa gagcaactcc atgctccgca
     4561 ttatttatag tccttatttt aaagttttat tagctctctt tacagaacag atgtgaagga
     4621 gttgagagga caatcaacta gattttattt ttagaatata aagaacattt ttaaaatgat
     4681 taaacagcat taactgtacc tcaggatctg cgcatgcatc tgaatagcac acggctcaaa
     4741 tggtcctttc cttttgttac atttagtagt tgtgccatct ttagtttttg ctttgaacat
     4801 tgttttccta aaagtcaact attactttcc catcaagttg gttttatagt tatgtctaaa
     4861 tttatggttc atgtcaaagt atttttgact taatatcctt ttaaaaatat ttaaactgat
     4921 ttattgctca attggtgata gctgagaaaa ttttttcaat atgtagaatt ttcatggtta
     4981 ttttgtatga attatttttc tgggtaagcc atctgccaca gaaattgaca ctatggtgag
     5041 attaatgtta atgaaatgag cagtagagaa gctactggat tgctttaaaa cattctttga
     5101 ttaaattact acatagttgg taagttcata gttttaagtt acttaattga agccctcaga
     5161 agttgcaaag aatttatctg ataaatctgc ctttgcacaa atgtgatact gatgcatgga
     5221 cggctttgcg gaatgacctt tgatatttgt gcctagtgga aggtatggag ctaaacaatt
     5281 aaagaactct tcattatgga taggcacata ttggatctct ggtattttgg gtagtggtat
     5341 taacttgaca attctaattt attttagtta gtatatgtag caagttagta tgtttgttag
     5401 tagtttattg tacttcattc cagttggtaa tatagttttc atcacactaa actttttata
     5461 ctaaatttct gtagaagctt gttgggtttg ccttcaccag aaggtacttt aaatacctac
     5521 catagctgat ttgttataaa gaaacaaaat gggtgttctt ctgtttcctt ttgattatgt
     5581 ttactgtaat tatttcattt tggatttata catttacaat tgaataagga ttataggttg
     5641 ataagctgtt tattgtgaaa agatgtgttt tgttacaaat acttgtttta aaaattaata
     5701 agcccccagg aagtacagca ttgactggca caactgccca tagtgagctt cccaactaac
     5761 tgccttcagt ggattcgggc aagtgcaaag tctttggcct attgtgtgac aaagaggtat
     5821 atattaaagg aaaagaaaaa tgacatgaat aagaaaattc cgtcaacaag gttggagtag
     5881 ggagttgttg aggggtttag tttgttttaa aaggtatgtg agggagtggt ggggtggatt
     5941 tgtgtttctg actttttttc tttaagcaaa ttccatatgt taccaaaagc acatgctgta
     6001 tattttcttc cccttttgtg tgtatatagt attttgaaag ataaatgaat tgggtatttg
     6061 tatgtgggat gtacaaaatt gtggccgctc tctttgtgga aggaaaaaac ataaatgaag
     6121 ttaatgcact tcttttccta gcccaaaagt cactgtgatt atattttttt aatgaagttt
     6181 agaaaaaaag ctgttgtctt ctcaattgta aaattagttt caaaatgctg cttctcttat
     6241 cattagtcta gtaattgttg aacttttctg caaactgcat tttacaaaat tgaaacttgg
     6301 aagctgtatt aacttttata gttaaacatt gtattaaata aactatacta taataaa
//
