LOCUS       XM_006718716            5552 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens PTPRF interacting protein alpha 1 (PPFIA1),
            transcript variant X1, mRNA.
ACCESSION   XM_006718716
VERSION     XM_006718716.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000011.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006718716.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 34% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5552
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
     gene            1..5552
                     /gene="PPFIA1"
                     /gene_synonym="LIP.1; LIP1; LIPRIN"
                     /note="PTPRF interacting protein alpha 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 43 ESTs, 120 long SRA reads, 6 Proteins, and 75%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:8500"
                     /db_xref="HGNC:HGNC:9245"
                     /db_xref="MIM:611054"
     CDS             226..4146
                     /gene="PPFIA1"
                     /gene_synonym="LIP.1; LIP1; LIPRIN"
                     /codon_start=1
                     /product="liprin-alpha-1 isoform X1"
                     /protein_id="XP_006718779.1"
                     /db_xref="GeneID:8500"
                     /db_xref="HGNC:HGNC:9245"
                     /db_xref="MIM:611054"
                     /translation="MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSML
                     EERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEFAALTKELNVCRE
                     QLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEV
                     LKALKSLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTD
                     GVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASL
                     SSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQR
                     EATSVHDLNDKLENEIANKDSMHRQTEDKNRQLQERLELAEQKLQQTLRKAETLPEVE
                     AELAQRVAALSKSDLLSSGSSAAKEAKLLELTSKLRKAEERHGNIEERLRQMEAQLEE
                     KNQELQRARQREKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREV
                     ESAKKQLEETQHDKDQLVLNIEALRAELDHMRLRGASLHHGRPHLGSVPDFRFPMADG
                     HTDSYSTSAVLRRPQKGRLAALRDEPSKVQTLNEQDWERAQQASVLANVAQAFESDAD
                     VSDGEDDRDTLLSSVDLLSPSGQADAHTLAMMLQEQLDAINKEIRLIQEEKENTEQRA
                     EEIESRVGSGSLDNLGRFRSMSSIPPYPASSLASSSPPGSGRSTPRRIPHSPAREVDR
                     LGVMTLPSPDSFLIQTSGPHQSVVYSSTSPPSSTPCYSDSSQHAQPSDLRKHRRKLPP
                     SREEVRDDKTTIKCETSPPSSPRALRLDRLHKGALHTVSHEDIRDIRNSTGSQDGPVS
                     NPSSSNSSQDSLHKAPKKKGIKSSIGRLFGKKEKGRPGQTGKEALGQAGVSETDNSSQ
                     DALGLSKLGGQAEKNRKLQKKHELLEEARRQGLPFAQWDGPTVVVWLELWVGMPAWYV
                     AACRANVKSGAIMSALSDTEIQREIGISNPLHRLKLRLAIQEIMSLTSPSAPPTSRTT
                     TGNVWLTHEEMETLAATPQTEDEEGSWAQTLAYGDMNHEWIGNEWLPSLGLPQYRSYF
                     MECLVDARMLDHLTKKDLRGQLKMVDSFHRNSFQCGIMCLRRLNYDRKELERKREESQ
                     SEIKDVLVWSNDRVIRWILSIGLKEYANNLIESGVHGALLALDETFDFSALALLLQIP
                     TQNTQARAVLEREFNNLLVMGTDRRFDEDDDKSFRRAPSWRKKFRPKDIRGLAAGSAE
                     TLPANFRVTSSMSSPSMQPKKMQMDGNVSGTQRLDSATVRTYSC"
ORIGIN      
        1 agacgccggc gccgcgcagc cgggcccgct cctcctccgc tccgccagtg tccggccgcg
       61 ggccggcctt agtgactggg gcggcgggcc ccggggccgc ggcgtggggc gggcaggcgg
      121 acgccggccg cgggctgctt tcgtcggctc ccaagctctc ccggagcgag cagccgcccg
      181 cgagccgccg cggagcctcc tcgcccgctc ccgccggcga gcaagatgat gtgcgaggtg
      241 atgccgacca tcagcgaagc agaaggcccc cctggaggag gtggaggcca tggttccggc
      301 tccccttcac agccagatgc agattcacat tttgaacagt tgatggtctc catgctagaa
      361 gaaagggacc gccttcttga tacactgaga gagactcaag aaacgctggc cttaacccag
      421 gggaagttac acgaggttgg tcatgaaaga gattccttgc agagacagct caacacggca
      481 cttccacagg agttcgcagc acttactaaa gaactcaatg tatgcaggga acagctcctt
      541 gaaagggaag aagaaattgc tgaactgaaa gcagaaagga ataacaccag gctgctgtta
      601 gagcatttgg aatgccttgt ctccaggcat gagcggtctc ttaggatgac cgtggtgaag
      661 agacaagcgc agtctccagc aggcgtgtcc agcgaagtgg aagtgctgaa agcactgaag
      721 tccttatttg aacaccacaa agctctggat gaaaaggtga gagagcgatt acgagtagca
      781 cttgaaagat gtagtttgtt agaagaggaa ttaggtgcca cacacaaaga gctaatgatt
      841 cttaaagaac agaataatca gaaaaaaact ctaacagatg gagtgctgga cataaaccat
      901 gaacaagaaa atacaccaag cacgagtgga aagagatctt ctgatggttc tttaagccac
      961 gaggaagacc ttgctaaagt aattgagctc caagaaatca taagtaagca gtcaagggaa
     1021 cagagccaaa tgaaagaacg cctggcttcc ctttccagtc atgtgacaga actggaagag
     1081 gatctggaca cggctagaaa agatctcatc aaatctgaag aaatgaacac aaaattgcaa
     1141 cgagatgtcc gtgaagccat ggcccaaaag gaagatatgg aagagagaat cactactctt
     1201 gaaaaacgct acctcgctgc acagcgtgaa gccacatctg tgcatgacct caatgataaa
     1261 cttgaaaatg aaattgcaaa taaagattct atgcatcgac agactgaaga taaaaaccgc
     1321 cagttacagg agcgcttgga attggcagag caaaagctgc aacagacact gaggaaggca
     1381 gagacgctcc cggaggtgga ggcggagctg gcccagaggg tggcagcgct ttccaagtct
     1441 gaccttttgt cttctgggag ctctgctgct aaggaagcta aactgttgga acttacttcc
     1501 aagcttagga aggctgaaga gagacacggc aacattgaag aaaggttacg acagatggaa
     1561 gcacagttgg aggagaagaa tcaagaactg cagcgggcaa ggcaaagaga aaaaatgaac
     1621 gaagaacata ataaacgttt atcagacact gttgacaagc tgctttcaga atctaatgag
     1681 aggcttcaac ttcatcttaa agagagaatg gctgctttgg aagataagaa ctctctttta
     1741 agagaagttg aaagtgcaaa aaagcagtta gaagaaacac aacacgataa ggatcagctt
     1801 gtcctaaaca ttgaagcact gagggctgaa ctagaccaca tgagactaag aggtgcttca
     1861 cttcatcatg gccgacccca cttgggcagt gtcccagatt tcaggttccc catggcagac
     1921 ggccacacag actcctacag caccagtgca gtgctgcggc gcccacagaa aggccggctg
     1981 gcagccctgc gagatgagcc ttccaaggta caaactctta atgagcagga ttgggaacgt
     2041 gcccagcaag ctagtgtctt ggcaaatgta gcacaagcat tcgagagtga tgctgacgtg
     2101 tctgatggtg aagatgacag ggacactctc ctcagctcag ttgacctgct atcgcccagc
     2161 gggcaggccg acgcgcacac actagccatg atgcttcagg agcagctgga cgccatcaac
     2221 aaagagatca ggttgattca ggaagaaaaa gaaaatacag agcagcgggc agaggagatt
     2281 gaaagtcgag ttggcagtgg aagtctagac aatcttggtc gttttagatc aatgagctcc
     2341 attcccccct accctgcttc ctcgcttgct agctcctccc ctccgggcag tgggcgctcc
     2401 accccacgaa ggatccctca cagcccagct cgggaagtgg acagactggg cgtcatgacc
     2461 cttccatctc cagattcatt tttaatccag acctcaggtc cccatcagtc agtagtttac
     2521 tcatccacct cccctcccag ttccacccca tgctatagcg attcttcaca gcatgctcag
     2581 cctagtgatt taaggaaaca tcgtagaaag ttgccacctt ccagagaaga ggtacgagat
     2641 gacaagacaa ccataaagtg tgaaacctcc ccgccttcct ccccgagagc ccttcggtta
     2701 gaccggctgc acaaaggggc gctgcacacc gtcagccacg aggacatcag ggacataagg
     2761 aactccacag gctcccagga tggtcccgtg agcaacccca gcagtagcaa cagtagccag
     2821 gactcgctcc acaaagcccc aaagaagaaa ggcattaagt cctccattgg ccgcttgttt
     2881 ggcaagaaag aaaagggccg acctggacaa actggcaaag aagcattagg acaagctggt
     2941 gtttccgaga cggataactc atctcaggat gccttgggac ttagcaaatt ggggggacag
     3001 gctgaaaaaa atcgtaaact tcaaaaaaag catgaattgc tggaggaagc ccggagacaa
     3061 ggtttacctt ttgcccaatg ggacgggcca acggttgtgg tctggctaga gctctgggtt
     3121 gggatgccag cctggtatgt ggctgcctgc cgagcaaacg tgaaaagcgg ggccatcatg
     3181 tcggccctgt ccgacacaga gatccagcgt gagattggca tcagcaaccc cctgcacagg
     3241 ctgaagctga ggctggccat ccaggagatc atgtcgctga ccagcccgtc tgccccgccc
     3301 acatctagaa cgaccacagg aaatgtctgg ttaacacacg aagagatgga aacgctcgca
     3361 gccacgccgc aaacggaaga tgaggaggga agctgggctc agacactcgc ctatggggac
     3421 atgaaccacg agtggatcgg caacgagtgg ctccccagcc tgggcctccc ccagtaccgc
     3481 agctacttca tggagtgcct tgtagacgcc aggatgctgg accacttgac caagaaagac
     3541 cttcgagggc agctgaaaat ggtcgacagt tttcacagaa acagtttcca gtgtggaatt
     3601 atgtgcctga gaaggttaaa ttatgaccgg aaagaactgg aaagaaaaag agaagaaagt
     3661 cagagtgaaa taaaagacgt gcttgtttgg agcaatgatc gagtgattcg ctggatcctg
     3721 tcaattggcc ttaaagaata tgcaaacaat cttatagaga gtggtgttca cggagcactt
     3781 ctggccttag atgaaacctt cgacttcagt gcactggcac tgctgttaca gatcccgacg
     3841 cagaacacac aggctcgtgc tgtcttggaa agagaattta acaacctttt ggtcatgggg
     3901 actgatagaa ggtttgatga agatgatgat aaaagcttta ggagagcacc ttcatggaga
     3961 aaaaagttta gaccaaagga cattcgtggc ttagctgctg ggtcagcaga gactctccct
     4021 gcaaacttcc gggtgacttc ttctatgtct tccccctcta tgcagccaaa gaagatgcag
     4081 atggacggca atgtatcagg aacacagagg ttggattctg ctacagtcag gacttactcc
     4141 tgctaaagtc tcctgttgtt tacccacact acttctacag atgattatgc agcatttgaa
     4201 tccaacaaag actacatttt ggaatccagt ggaatcttta atcttgttaa tacttgttat
     4261 atggacccta agatatttta ttacagagtt tttaattagt gaaaaattca tgaataccat
     4321 agagaaaata ttttagaatt taatgtttct tatatttatg taaacttatg actcttcatt
     4381 tatatagtta cttacttttt catgtatatc caggctataa atatcctttc aaatcatgtt
     4441 cttataccta attttagtct ttcaaatgaa tgtactgtaa tgcttgtatg tataaatcct
     4501 atgaatagag ggcttttgta aattatgcat ttattgtaat tatcattaat tttttaatga
     4561 taaaccatga caaaggattt tacgtttata aaattatgac agaagccatg tgcattatcc
     4621 tttacggacg cagcctagct ctacagcaat catcctgaaa taagcatacc taatttcaag
     4681 caattgttgt attttcatga ctgaccttaa ctgtactttt tctagcaaga gatgctttat
     4741 tctgcagcat gaacagattt aaaatggctg gtgttaaata tcagctccta ataagatgtg
     4801 gactgaaaac actatcacaa cactatgaga agcccctagc actggttaac gctttcctag
     4861 cctagtctct ggatttgggg agcttgtctt cagtggctga gactgtgagc tgggagcagt
     4921 tctctcagct ggagagactc gggatggggt aacctgggga ccagtctagc ccctgcaccc
     4981 tcttccctgc ctctgctcct tgggagcggg tggagagaca cccatgtggc tccccttagg
     5041 gccagcacca agcaccacgc tctcatcctg caagtcggcg cacacagtgg atgaaggcag
     5101 gagacccaga aagcagtgca gtgcagctct aataaaggcc ttatttttct tatgtaaatc
     5161 atctttttac atttgtttgt aaacatgttt aaagaacgaa cctagtggga catttttaga
     5221 ctttgatgct ctagccattt tggattgtgt aagttgcaga tgtggctttt actttttaaa
     5281 tggcatatta acaagccagc aaagtgtgtc agaccatggc gtggtattta ttgtgcagca
     5341 gatccagaga cagaggcagc ctgtcttttc agttggtttc tgcttttaat ttacttgtac
     5401 aattcattgt tactgttctg tttttctatt aatcttttgt caacttcctg attatgtaac
     5461 aaagtatgta cagtctactt ttgaactatt tttatcacag tattatttat tgctttcttt
     5521 caataaagta ctgaagcatt ttccactgcc aa
//
