LOCUS       NM_001394376            7057 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens POU class 2 homeobox 2 (POU2F2), transcript variant 8,
            mRNA.
ACCESSION   NM_001394376 XM_011527040
VERSION     NM_001394376.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7057)
  AUTHORS   Li,J., Li,P.T., Wu,W., Ding,B.N., Wen,Y.G., Cai,H.L., Liu,S.X.,
            Hong,T., Zhang,J.F., Zhou,J.D., Qian,L.Y. and Du,J.
  TITLE     POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits
            ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis
  JOURNAL   Epigenomics 16 (4), 215-231 (2024)
   PUBMED   38318853
  REMARK    GeneRIF: POU2F2-mediated upregulation of lncRNA PTPRG-AS1 inhibits
            ferroptosis in breast cancer via miR-376c-3p/SLC7A11 axis.
REFERENCE   2  (bases 1 to 7057)
  AUTHORS   Nazarov,I.B., Zilov,D.S., Gordeev,M.N., Potapenko,E.V.,
            Yeremenko,N. and Tomilin,A.N.
  TITLE     Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates the
            Specificity of DNA Recognition by the POU-Domain Factors OCT1 and
            OCT2 in a Monomeric Configuration
  JOURNAL   Biomolecules 14 (1), 123 (2024)
   PUBMED   38254723
  REMARK    GeneRIF: Transcriptional Coactivator BOB1 (OBF1, OCA-B) Modulates
            the Specificity of DNA Recognition by the POU-Domain Factors OCT1
            and OCT2 in a Monomeric Configuration.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7057)
  AUTHORS   Ungureanu,I.A., Cohen-Aubart,F., Heritier,S., Fraitag,S.,
            Charlotte,F., Lequain,H., Helias-Rodzewicz,Z., Haroche,J.,
            Donadieu,J. and Emile,J.F.
  TITLE     OCT2 expression in histiocytoses
  JOURNAL   Virchows Arch 483 (1), 81-86 (2023)
   PUBMED   36754897
  REMARK    GeneRIF: OCT2 expression in histiocytoses.
REFERENCE   4  (bases 1 to 7057)
  AUTHORS   Garcia-Caballero,D., Hart,J.R. and Vogt,P.K.
  TITLE     The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven
            cell proliferation by controlling the expression of OCT2
  JOURNAL   Cell Death Dis 14 (2), 168 (2023)
   PUBMED   36849510
  REMARK    GeneRIF: The MYC-regulated lncRNA LNROP (ENSG00000254887) enables
            MYC-driven cell proliferation by controlling the expression of
            OCT2.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7057)
  AUTHORS   Ren,W., Ren,J., Zhang,N., Liu,X., Deng,Y., Jiang,Y., Yan,B.,
            Xiao,X. and Yu,H.
  TITLE     CBX7 represses the POU2F2 to inhibit the PD-L1 expression and
            regulate the immune response in bladder cancer
  JOURNAL   Biochem Biophys Res Commun 613, 12-18 (2022)
   PUBMED   35526483
  REMARK    GeneRIF: CBX7 represses the POU2F2 to inhibit the PD-L1 expression
            and regulate the immune response in bladder cancer.
REFERENCE   6  (bases 1 to 7057)
  AUTHORS   Muller-Immergluck,M.M., Schaffner,W. and Matthias,P.
  TITLE     Transcription factor Oct-2A contains functionally redundant
            activating domains and works selectively from a promoter but not
            from a remote enhancer position in non-lymphoid (HeLa) cells
  JOURNAL   EMBO J 9 (5), 1625-1634 (1990)
   PUBMED   2328728
REFERENCE   7  (bases 1 to 7057)
  AUTHORS   Scheidereit,C., Cromlish,J.A., Gerster,T., Kawakami,K.,
            Balmaceda,C.G., Currie,R.A. and Roeder,R.G.
  TITLE     A human lymphoid-specific transcription factor that activates
            immunoglobulin genes is a homoeobox protein
  JOURNAL   Nature 336 (6199), 551-557 (1988)
   PUBMED   2904654
REFERENCE   8  (bases 1 to 7057)
  AUTHORS   Muller,M.M., Ruppert,S., Schaffner,W. and Matthias,P.
  TITLE     A cloned octamer transcription factor stimulates transcription from
            lymphoid-specific promoters in non-B cells
  JOURNAL   Nature 336 (6199), 544-551 (1988)
   PUBMED   2904653
REFERENCE   9  (bases 1 to 7057)
  AUTHORS   Clerc,R.G., Corcoran,L.M., LeBowitz,J.H., Baltimore,D. and
            Sharp,P.A.
  TITLE     The B-cell-specific Oct-2 protein contains POU box- and homeo
            box-type domains
  JOURNAL   Genes Dev 2 (12A), 1570-1581 (1988)
   PUBMED   3265124
REFERENCE   10 (bases 1 to 7057)
  AUTHORS   Ko,H.S., Fast,P., McBride,W. and Staudt,L.M.
  TITLE     A human protein specific for the immunoglobulin octamer DNA motif
            contains a functional homeobox domain
  JOURNAL   Cell 55 (1), 135-144 (1988)
   PUBMED   2901913
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC010247.9, AC024076.4 and
            AC022515.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Apr 16, 2021 this sequence version replaced XM_011527040.3.
            
            Summary: The protein encoded by this gene is a homeobox-containing
            transcription factor of the POU domain family. The encoded protein
            binds the octamer sequence 5'-ATTTGCAT-3', a common transcription
            factor binding site in immunoglobulin gene promoters. Several
            transcript variants encoding different isoforms have been found for
            this gene. [provided by RefSeq, Oct 2011].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000692977.1/ ENSP00000509972.1
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AC010247.9         23538-23600         c
            64-129              AC024076.4         38049-38114         c
            130-164             AC024076.4         37882-37916         c
            165-221             AC024076.4         37664-37720         c
            222-404             AC024076.4         32788-32970         c
            405-510             AC024076.4         15254-15359         c
            511-602             AC024076.4         15065-15156         c
            603-764             AC024076.4         11620-11781         c
            765-906             AC024076.4         11326-11467         c
            907-1055            AC024076.4         11083-11231         c
            1056-1232           AC024076.4         10824-11000         c
            1233-1272           AC024076.4         9394-9433           c
            1273-1299           AC022515.5         1-27
            1300-1501           AC022515.5         1586-1787
            1502-1575           AC022515.5         1916-1989
            1576-7057           AC022515.5         2265-7746
FEATURES             Location/Qualifiers
     source          1..7057
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..7057
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="POU class 2 homeobox 2"
                     /db_xref="GeneID:5452"
                     /db_xref="HGNC:HGNC:9213"
                     /db_xref="MIM:164176"
     exon            1..63
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..1910
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="isoform 8 is encoded by transcript variant 8; POU
                     domain, class 2, transcription factor 2; homeobox protein;
                     octamer-binding protein 2; octamer-binding transcription
                     factor 2; lymphoid-restricted immunoglobulin
                     octamer-binding protein NF-A2"
                     /codon_start=1
                     /product="POU domain, class 2, transcription factor 2
                     isoform 8"
                     /protein_id="NP_001381305.1"
                     /db_xref="CCDS:CCDS92631.1"
                     /db_xref="GeneID:5452"
                     /db_xref="HGNC:HGNC:9213"
                     /db_xref="MIM:164176"
                     /translation="MVHSSMGAPEIRMSKPLEAEKQGLDSPSEHTDTERNGPDTNHQN
                     PQNKTSPFSVSPTGPSTKVGILSGLHLTFWGPGPCLSPPQIKAEDPSGDSAPAAPLPP
                     QPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHLQPPAQFLLPQAQQSQPGL
                     LPTPNLFQLPQQTQGALLTSQPRAGLPTQAVTRPTLPDPHLSHPQPPKCLEPPSHPEE
                     PSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNM
                     CKLKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFAL
                     EKSFLANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKP
                     ASYSPHMVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPP
                     LNSIPSVTPPPPATTNSTNPSPQGSHSAIGLSGLNPSTGSTMVGLSSGLSPALMSNNP
                     LATIQALASGGTLPLTSLDGSGNLVLGAAGAAPGSPGLVTSPLFLNHAGLPLLSTPPG
                     VGLVSAAAAAVAASISSKSPGLSSSSSSSSSSSSSTCSETAAQTPGGPGGPEAGSKPE
                     "
     exon            64..129
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            130..164
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            165..221
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            222..404
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            405..510
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            511..602
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            603..764
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            765..906
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            907..1055
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1232
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1299
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1501
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1575
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..7057
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5964..5969
                     /regulatory_class="polyA_signal_sequence"
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="hexamer: GATAAA"
     polyA_site      5987
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="major polyA site"
     regulatory      7024..7029
                     /regulatory_class="polyA_signal_sequence"
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="hexamer: AATAAA"
     regulatory      7032..7037
                     /regulatory_class="polyA_signal_sequence"
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="hexamer: ATTAAA"
     polyA_site      7044
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
                     /note="major polyA site"
     polyA_site      7057
                     /gene="POU2F2"
                     /gene_synonym="Oct-2; OCT2; OTF2"
ORIGIN      
        1 acagttgttc ccccagccct ggcggggcgg gcagcatggt tcactccagc atgggggctc
       61 cagaaataag aatgtctaag cccctggagg ccgagaagca aggtctggac tccccatcag
      121 agcacacaga caccgaaaga aatggaccag acactaatca tcagaacccc caaaataaga
      181 cctccccatt ctccgtgtcc ccaactggcc ccagtacaaa ggtgggcatt ctctctggcc
      241 tccacttaac attctggggt cccggaccct gcctctctcc cccccagatc aaggctgaag
      301 accccagtgg cgattcagcc ccagcagcac ccctgccccc tcagccggcc cagcctcatc
      361 tgccccaggc ccaactcatg ttgacgggca gccagctagc tggggacata cagcagctcc
      421 tccagctcca gcagctggtg cttgtgccag gccaccacct ccagccacct gctcagttcc
      481 tgctaccgca ggcccagcag agccagccag gcctgctacc gacaccaaat ctattccagc
      541 tacctcagca aacccaggga gctcttctga cctcccagcc ccgggccggg cttcccacac
      601 aggccgtgac ccgccctacg ctgcccgacc cgcacctctc gcacccgcag ccccccaaat
      661 gcttggagcc accatcccac cccgaggagc ccagtgatct ggaggagctg gagcaattcg
      721 cccgcacctt caagcaacgc cgcatcaagc tgggcttcac gcagggtgat gtgggcctgg
      781 ccatgggcaa gctctacggc aacgacttca gccagacgac catttcccgc ttcgaggccc
      841 tcaacctgag cttcaagaac atgtgcaaac tcaagcccct cctggagaag tggctcaacg
      901 atgcagagac tatgtctgtg gactcaagcc tgcccagccc caaccagctg agcagcccca
      961 gcctgggttt cgacggcctg cccggccgga gacgcaagaa gaggaccagc atcgagacaa
     1021 acgtccgctt cgccttagag aagagttttc tagcgaacca gaagcctacc tcagaggaga
     1081 tcctgctgat cgccgagcag ctgcacatgg agaaggaagt gatccgcgtc tggttctgca
     1141 accggcgcca gaaggagaaa cgcatcaacc cctgcagtgc ggcccccatg ctgcccagcc
     1201 cagggaagcc ggccagctac agcccccata tggtcacacc ccaagggggc gcggggacct
     1261 taccgttgtc ccaagcttcc agcagtctga gcacaacagt tactacctta tcctcagctg
     1321 tggggacgct ccaccccagc cggacagctg gagggggtgg gggcgggggc ggggctgcgc
     1381 cccccctcaa ttccatcccc tctgtcactc ccccaccccc ggccaccacc aacagcacaa
     1441 accccagccc tcaaggcagc cactcggcta tcggcttgtc aggcctgaac cccagcacgg
     1501 gaagcacaat ggtggggttg agctccgggc tgagtccagc cctcatgagc aacaaccctt
     1561 tggccactat ccaagccctg gcctctggtg gaaccctgcc ccttaccagc cttgatggca
     1621 gcgggaatct ggtgctgggg gcagccggtg cagccccggg gagccctggc ctggtgacct
     1681 cgccgctctt cttgaatcat gctgggctgc ccctgctcag caccccgcct ggtgtgggcc
     1741 tggtctcagc agcggctgcg gctgtggcag cctccatctc cagcaagtct cctggcctct
     1801 cctcctcatc ctcttcatcc tcatcctcct cctcctccac ttgcagcgag acggcagcac
     1861 agacccctgg aggtccaggg gggcccgagg cagggtccaa acctgagtga gggccagcca
     1921 tgcctcccct cccattcctc tggtccctgc cttggtccct tgcctgggaa gagggcgagg
     1981 aggccagtgg tggggacgca gagggtcctc agagcaggag tgacaaggga ggaaagacca
     2041 aaaaaacaac caaccaaaaa aaaaaaaaaa aaggaaagaa actaaccaac aaaagagaaa
     2101 accaaaaata atcacaacag aaaccagctg ccccaaagga accagaggtg aaaaacaaac
     2161 aaaaaaaaac caaaaacaaa ccaaaaaaaa aaaaaaccca caaaatcaaa caaaccaaaa
     2221 aaccagtcgc gagccagacc tcagcgtgct caccctcact gctacgacgc caaataaaaa
     2281 ccccagccag gggcggagaa gcctccagca ggtcagacct catgccaccg agccctggct
     2341 gtgggaccaa cccccaaccc tgcctccccc gtgggggcta cagaaggaaa aagagaagat
     2401 gccagcttcc taatcccagc ccccagccct gggccagcga agacagggca cagcctgggc
     2461 agatgggctg gggcttagca ccacccacca aatgttcttt tccagaaggt gaaagagaaa
     2521 gggcctgaac aaccttacac caaatattca gtagcttcat ccaaaggatg tacagaattt
     2581 ttagcattgt gctcaacaga atgtgtccct accatgtgtc cccttctccc ctggccccca
     2641 gctctcccca cctgggcagg gggtcttgct ttaacctcct ccctcccccc agcaggggag
     2701 agttcaaggg aaggcctgcg gacaactttt catcccctgt tcctccctct tttccccttt
     2761 gaagggtggg ctaggccatt ttgccaagtt ctagctctca caagtccctc ctcaaccctg
     2821 tcaccctcct ctgctctgga actgactccc tccccagcct atgggaaggt ggaaatttca
     2881 ggcaagaggg gatgaagaca ttcagttgag ggcattcagt tgtctttttc catcctgtct
     2941 gtttccctga aaaaaaaaaa aattcatatt ccagtgccta tccgtgggat ccttcacgtt
     3001 ctttgacatt aaccagaaac caaaaagaga actcacctcg cttttcccac cctgtgcccc
     3061 tctggtactg gcgaatgcct ctccctcccc ccacatgcac gcacgcacac accccagtgg
     3121 tggggttcct cgagatggca tccccatcag ggtccatgtg gtggggacag tgccacagcc
     3181 tgtggtcccc atctgagagg gcgcggtggt ggccaccact cccacaagac ctccacaact
     3241 cttggctgga ccctgtgttt gaccagcccc ggacacgtct ccactgacga cggacagagg
     3301 agagacacca ctgggagcca ccctgccctc ctgctattgt ggaggccaac aaagttttga
     3361 accgaaaacc aaaaaaacag aaacaaacaa acaataaatt taaactagaa aaaaaattta
     3421 tatatatata taaacatata tatatatata tatataaaag ggaaagaaga tgaggactct
     3481 tcaagaataa gatggaaccg cgaggcggag ccaagcccct gcaccggtgg tccaggccct
     3541 tgttccccaa ggcggatgga aggacggatg cttctttctc ttcacaaata cctcatggac
     3601 gttgtctttg ggaaagccgg agggggcggc tggggcaggg cctgtccctc ggccagggca
     3661 gatggaagcg ggtgggcggg gctgagagag ggtatcaggg acaggggtga agagccccaa
     3721 actcccctcc caaatcaact gaaaaagctt taaaaaaaga caggaaaaaa aggagtaaga
     3781 aagcaaaaag aacagatgaa ggaaaactta acaacttttg ggtggtttga ttcctccttt
     3841 gatttctttt tcggttctct tttgtctgac ctctctcctc ccctccttcc tctctcctcc
     3901 cctccttcct ctctcctctc ctccttcctg tctcctctct ctccctttgc tctcctctct
     3961 tctctctcaa tcttgttctt tctgtgtctc tcctcaaacc aaagtgttgc agtgaaggac
     4021 acgagccatt gaaatcaggg tggggcctga cagccgtagt gtggcccctg ccccttgttg
     4081 ggcaggagca gagagagagg agagccctga gaccgcaggg ctttggcctg ggcagcttcc
     4141 actttctgcc ggacactctg aggagaggca gatggagctc caggcctcag cgttctcttt
     4201 tttccttgtc tcccttctcc cacccgggaa atgaaactgt tgggctgggc gacggaggca
     4261 gcagagactc ggccattgca ggggcctctg ggtgccttgt ccgggcagtg gtgaagtagc
     4321 cgcccctccc accccggcac gatggggcct ggcacctcgt ctacccaacc tcaccggaat
     4381 gtaagcatct ccgctgaacg actccctgcc cttaccctac ctctgagttt gtccatgttt
     4441 atttcctgaa gagagaaggg actggcaaga gggcttgggc cccagcccaa gggtggagag
     4501 ggggccaagg gctcctgacc aaataggaag gacatttgag cagagcaaaa tgaaaggaat
     4561 tacaaccaaa aaccccctcc gagaagacag gcagcatgga aggcatggtg gagatgactc
     4621 aaacaaaaac tatgattcta gaccaaaaag gaaaaaaaaa aaaaaaaaag gaaagaaaat
     4681 ccaggactca ccaccaccca cttcatcctg cttcctcccc atcaagtccc accacctggg
     4741 acctctcccc accccagtat gtgggagtgg ggtaaagagg agaggaggag cagggggcag
     4801 ggatggggca gatgccctga tgttggtgga gggacccctg tgcagccggg ggtgctgggg
     4861 accctcccca tccaaccctc acacctagga aaagaaaaac aagaaaaaaa aattcctggg
     4921 agggggaaaa ataaccaaat cccaagcttt aactacagct gtgaaaccaa atattgggaa
     4981 gggggtagga gggagggagg ggcaggtgag ccccaggtct ccccctgggc ccccctcccc
     5041 tgaggactcg agataaggca ccaaatacct catagaactt taatgttaaa aaaaggaaac
     5101 caaatatcgt tggctggggg ccagccaggg caaggggctg gggggctgga gggagccagg
     5161 gttgggaagg tgatggggga attcatgccc cccaccccca tctgcccctt acactctggt
     5221 cccccgtctc gactccggga aacaaaacta tctcatcgtt tttattttgt ggtctgtaca
     5281 gagcctgtgt ccgtgtgtct gtgtatgagc gagagagttg gagggctggg gagctttatg
     5341 tgggggatgg ggagggcaac cccaggctag gctatgggct aggttagatg tccgaggttg
     5401 ggggccaagg gcctgggcta gaaagagagg agagatgagt gggttggagc agtggggagc
     5461 cctctgaatt tctcttctcc ccaaccctga cctcctactt aagggaggga cagagactgg
     5521 gtctacccta atggtgggcc ttttcattgt gccaaaaaaa aaaaaaaaaa aattgatgcc
     5581 agtaactaaa ccacctctct ctgttctctt ctggggggtg gggtgggtgt gtgtgtgggg
     5641 gtgggtaggg atggggaacc caagccccag taggagttgg ggctgagatc aggaggaggg
     5701 gaaggatatg agttttccat ccatctccct ggagaaggcc atgacgggct ctccaagccc
     5761 tggggagatc tggcgaggga ctagccaagt cagggtgacc tcttgacctg actagttttt
     5821 ctaacccaca tgaacaccag ggtgcctctc tcttcctcta gcccagggta gggggacctg
     5881 agtgagagag agagtgagac agacagcaag attgagacac gcgggccccc actggtctct
     5941 gagtgggaaa ggcaagtgcg agagataaag gcctccaaga gaaaaaagaa acaaaccaaa
     6001 gatttaacca tttaaaaaaa aaaaaaaacc cacagacaac tccgctacct ttttatatgt
     6061 tggaaaaaaa gtgaaaaaaa attaaaaata aaaataaaaa aaaatacaca aaaactccaa
     6121 gccgcaagtc cttcatgcgg tttaaacttt gacctcagca gtctccaaag caagacgacg
     6181 atgacaaagg cggaaacaaa gaaaaaataa tgtatatttt taagtatttg tccttgaatt
     6241 gttagctcct tgttaaacaa acaaaaggag agaaaaatcc agagagaagt gttgctggga
     6301 tggagacaac tatttactat gtctgtgacc cctcccttct gcctccctcc ccttcctctc
     6361 tttcctgtcc tctatccttg ctgcccctcc cccaatatgt cccccaaacc caggggctca
     6421 gtatttattt atttatataa ttgcagggtg actgggggcc tctctcggca actcgtagag
     6481 agcctttgga taatggcagg gtggggaatg ggcgaggagt ctttgggaag agcaggggcc
     6541 tgaactttca actcctttct ggcctcttgt cccactgctt ccaccatcac cttccaaatc
     6601 cagggctgca ctagggcaag gtgaccaccc tacttggtaa agacctgatt ggcgcagccc
     6661 attctggtgt gggtgtcttt caccacccag aatgaccagg ttggaatggg ggtgggtgaa
     6721 gttggagggg gtggcaagta caaggcaagg gtgcccagga accggcatcc agaaatcagc
     6781 cctggagtag acctgccttt cctccatcct taccaagtta gcctcccttt cagttccgtc
     6841 tgacccctgt gttggtagcc ccttccttcc cttcctgtac cccctccgtc tcttctcgtg
     6901 gtagcgggtt agtgtttcag tgttcttaac tccaatctgc ttgttcattg tacaatgtgc
     6961 ttcttttaag gccccatttt tgtaacttga gtgtgtcatt catctgaaca acaaacatca
     7021 aaaaataaaa aattaaaaac tgtacagaga gaaatga
//
