LOCUS       NM_001145442            6666 bp    mRNA    linear   PRI 05-FEB-2024
DEFINITION  Homo sapiens POTE ankyrin domain family member M (POTEM), mRNA.
ACCESSION   NM_001145442 XR_040579 XR_040580
VERSION     NM_001145442.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6666)
  AUTHORS   Chang,K.W., Yang,P.Y., Lai,H.Y., Yeh,T.S., Chen,T.C. and Yeh,C.T.
  TITLE     Identification of a novel actin isoform in hepatocellular carcinoma
  JOURNAL   Hepatol Res 36 (1), 33-39 (2006)
   PUBMED   16824795
REFERENCE   2  (bases 1 to 6666)
  AUTHORS   Hahn,Y., Bera,T.K., Pastan,I.H. and Lee,B.
  TITLE     Duplication and extensive remodeling shaped POTE family genes
            encoding proteins containing ankyrin repeat and coiled coil domains
  JOURNAL   Gene 366 (2), 238-245 (2006)
   PUBMED   16364570
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL929601.4 and AL589182.4.
            
            On or before Feb 28, 2009 this sequence version replaced
            XR_040580.1, XR_040579.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2148874,
                              SAMEA2158188 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000547889.6/ ENSP00000448062.2
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-573               AL929601.4         104790-105362
            574-688             AL929601.4         110116-110230
            689-862             AL929601.4         110390-110563
            863-969             AL929601.4         113405-113511
            970-1107            AL929601.4         114822-114959
            1108-1178           AL929601.4         117430-117500
            1179-1249           AL929601.4         122767-122837
            1250-1294           AL929601.4         124525-124569
            1295-1461           AL589182.4         641-807
            1462-1580           AL589182.4         9427-9545
            1581-6666           AL589182.4         11053-16138
FEATURES             Location/Qualifiers
     source          1..6666
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..6666
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /note="POTE ankyrin domain family member M"
                     /db_xref="GeneID:641455"
                     /db_xref="HGNC:HGNC:37096"
     exon            1..573
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1579
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /note="prostate-specific P704P; ANKRD26-like family C
                     member ENSP00000349402"
                     /codon_start=1
                     /product="putative POTE ankyrin domain family member M"
                     /protein_id="NP_001138914.1"
                     /db_xref="CCDS:CCDS73609.1"
                     /db_xref="GeneID:641455"
                     /db_xref="HGNC:HGNC:37096"
                     /translation="MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFPWCRGSGKSNVG
                     TSGDHDDSAMKTLRSKMGKWCRHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWC
                     CHCFPCCRGSGKSKVGPWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVM
                     LKDTDMNKKDKQKRTALHLASANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQE
                     DECALMLLEHGTDPNIPDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPL
                     LLGVHEQKQQVVKFLIKKKANLNALDRYGRTVLILAVCCGSASIVSLLLEQNIDVSSQ
                     DLSGQTAREYAVSSRHNVICQLLSDYKEKQILKVSSENSNPEQDLKLTSEEESQRLKG
                     SENSQPEEMSQEPEINKGGDRKVEEEMKKHGSTHMGFPENLPNGATADNGDDGLIPPR
                     KSRTPESQQFPDTENEQYHSDEQNDTQKQLSEEQNTGILQDEILIHEEKQIEVAENEF
                     "
     exon            574..688
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            689..862
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            863..969
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1107
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1178
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1179..1249
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1294
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1295..1461
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1580
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..6666
                     /gene="POTEM"
                     /gene_synonym="ACT; P704P; POTE14beta"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtagacgcg atctgctggc tactaccggc ctcccctggc tgttaaaagc agatggtggc
       61 tgaggctggt tcaatgccgg ctgcctcctc tgtgaagaag ccatttggtc tcagaagcaa
      121 gatgggcaag tggtgccgcc actgcttccc ctggtgcagg gggagcggca agagcaacgt
      181 gggcacttct ggagaccacg atgattctgc tatgaagaca ctcaggagca agatgggcaa
      241 gtggtgccgc cactgcttcc cctggtgcag ggggagcggc aagagcaacg tgggcacttc
      301 tggagaccac gacgactctg ctatgaagac actcaggagc aagatgggca agtggtgctg
      361 ccactgcttc ccctgctgca gggggagcgg caagagcaaa gtgggcccct ggggagacta
      421 cgacgacagc gctttcatgg agccgaggta ccacgtccgt cgagaagatc tggacaagct
      481 ccacagagct gcctggtggg gtaaagtccc cagaaaggat ctcatcgtca tgctcaagga
      541 cactgacatg aacaagaagg acaagcaaaa gaggactgct ctacatctgg cctctgccaa
      601 tggaaattca gaagtagtaa aactcctgct ggacagacga tgtcaactta atatccttga
      661 caacaaaaag aggacagctc tgacaaaggc cgtacaatgc caggaagatg aatgtgcgtt
      721 aatgttgctg gaacatggca ctgatccgaa tattccagat gagtatggaa ataccgctct
      781 acactatgct atctacaatg aagataaatt aatggccaaa gcactgctct tatacggtgc
      841 tgatatcgaa tcaaaaaaca agcatggcct cacaccactg ttacttggtg tacatgagca
      901 aaaacagcaa gtggtgaaat tcttaatcaa gaaaaaagca aatttaaatg cactggatag
      961 atatggaaga actgttctca tacttgctgt atgttgtgga tcggcaagta tagtcagcct
     1021 tctacttgag caaaacattg atgtatcttc tcaagatcta tctggacaga cggccagaga
     1081 gtatgctgtt tctagtcgtc ataatgtaat ttgccagtta ctttctgact acaaagaaaa
     1141 acagatacta aaagtctctt ctgaaaacag caatccagaa caagacttaa agctgacatc
     1201 agaggaagag tcacaaaggc ttaaaggaag tgaaaatagc cagccagagg aaatgtctca
     1261 agaaccagaa ataaataagg gtggtgatag aaaggttgaa gaagaaatga agaagcacgg
     1321 aagtactcat atgggattcc cagaaaacct gcctaacggt gccactgctg acaatggtga
     1381 tgatggatta attccaccaa ggaaaagcag aacacctgaa agccagcaat ttcctgacac
     1441 tgagaatgaa cagtatcaca gtgatgaaca aaatgatact cagaagcaac tttctgaaga
     1501 acagaacact ggaatattac aagatgagat tctgattcat gaagaaaagc agatagaagt
     1561 ggctgaaaat gaattctgag ctttctctta gttataagaa agaaaaagac ctcttgcatg
     1621 aaaatagtac gttgcaggaa gaaattgtca tgctaagact ggaactagac gtaatgaaac
     1681 atcagagcca gctaagagaa aagaaatatt tggaggaaat tgaaagtgtg gaaaaaaaga
     1741 atgataatct tttaaagggt ctacaactga atgagctcac catggatgat gatactgccg
     1801 tgctcgtcat tgacaacggc tctggcatgt gcaaggccgg ctttgcaggt gacgatgccc
     1861 cccgggctgt cttcccttcc atcgtggggt gccccaggca ccagaacatg atggggggca
     1921 tgcgtcagat ggagtcctat gtgggcaatg aggcccagag caagagaggc atcctgaccc
     1981 tgaagtaccc catggagcac ggcatcatca ccaactggga cgacatggag aagatctggc
     2041 accacacctt ctacaatgag ctgcgtgtgg ctcccgagga gcaccccatc ctgctgaccg
     2101 aggcacccct gaaccccaag gccaaccgtg agaagatgac ccagatcatg tttgagacct
     2161 tcaacacccc agccatgtac gtggccatcc aagccgtgct gtccttgtac acctctggcc
     2221 gtactactgg cattgtgatg gactctggtg acggggtcac ccacactgtg cccatctatg
     2281 aggggaatgc cctcccccat gccaccctgc gcctagacct ggctggccgg gaactgactg
     2341 actacctcat gaagatcctc accgagcgtg gctatagttt caccaccatg gccgagcagg
     2401 aaatcgtgcg tgacatcaca gagaagctgt gctatgttgc cctggacttc gagcaggaga
     2461 tggccacagc ggcctccagc tcctccctag agaacagcta tgagctgccc aacggccagg
     2521 tcatcaccat tagcaacgag cggttccgct gccccgaggt gctcttccag ccttgcttcc
     2581 tgggcatgga atcctgtggc atccacgaaa ctaccttcaa ctctatcatg aagtctgatg
     2641 tggacatcca caaagacctg tacaccaaca cagtgctatc tggtggcacc accatgtacc
     2701 ctggcattgc ccacaggatg cagaaggaga tcgctgccct ggcgcctagc acgatgaaga
     2761 tcaagattgt tgctcctccc aagcgcaagt actccgtgtg ggtcggtggc tccatcctgg
     2821 cctcgctgtc caccttccag cagatgtgga tcagcaagca ggagtatgat gagtcaggcc
     2881 cctccattgt ccaccgcaaa tgcttctagg tggacgctga cttagttgca ttacaccctt
     2941 tcttgacaaa accaaacttc gcagaaagcc acatgagatt ggtatggctt taattgtttt
     3001 cttatttcat tttttgtttt gttttttatt ggcttgactc aggatttaaa aactggaatg
     3061 gtgaaggcga gagcagttgg ttggagtgag cttcccccaa agttctacaa tgtggctgag
     3121 gactttgatc gtacattgtt tttcttttca atagtcattc caaatattgt gagatgcatt
     3181 gtttcaggaa gccccttgcc cttctaaaag ccaccccact tctctctaag gagaatggcc
     3241 cagtcctctc cctaattcac acaggggagg tgatggcatt gctttcatgc aaattacgta
     3301 atgcagaatt ttttgaatct ttgcctaaat actttttaat tttgttttat ttagaatgat
     3361 cagccttcgc ggcccccctt ttttgtaccc caacttgggg tgtatgaagg cttttggtct
     3421 ccctgagagt ggctggaggc agccagggct tacctgtact ctgacttaag gagagttgga
     3481 aaaaagtgca caccttaaaa aaaattcaat gaggaagcat taacaaaaac agtatttctg
     3541 tacagtggac agcttagcat gttgacaact gagaataaaa tgctcagttc tgaactggac
     3601 aatgtaagac acaacgacga aacactggaa atggaaattc aattacatca ttgtagactg
     3661 gctactgctc tacatgattg tgaccaaagt cagagagctg aaagagactt ctttccagag
     3721 aacaagacat gaacaggttt atttacagaa gacaatgaat tctcatttgt ctaacctaaa
     3781 agattacaga atctttctca acaagtctaa tgtagacagt aaaatcaaca ggctaaaaat
     3841 taagttccat gaaacaagat aaaactctga gagaaaagat ggggcaggcc gccatctttc
     3901 ccgttcgggc aacttagtca ttccagcctg agggctttgg agagtacaaa ctgaccaggg
     3961 aaagaagaga tcccagagca cagcatagct gctttaccaa atcatggcca gactgcttct
     4021 gtaagcaggc ccctgatcct gttccacctc actggacagg acctcccaac tggggcctcc
     4081 agctaccccc accagcatcc cttggccaat ggaaatttga aatgttcctg ggacagagct
     4141 cctggagaga ggggcaggcc accacctttg ctgtttgggt gactagccgt tctggcctgc
     4201 aggctttgga gagcccaagc tgacaagggg tagaagaggt gcctcagcac agcacagcca
     4261 cgctacgaaa acatggccag actcttgttt aagtcagtcc ccgaacacat ttctagtcag
     4321 tgggtgaagt ctttcaacca gggtctctgg ctaccttgac tgctgttctc tggccgacag
     4381 aggtctcagg cctccctgag tcagagctcc cggggggagg accagattgt catctttgct
     4441 gtttgggtga cccagccatt tcagccttag ggcttcagag tgtctgaggt agccaggggc
     4501 tgaagtgaac ccccagcaca gcacagctgc tctataaaaa cgtggccaga ctttttcttt
     4561 aagcaagtcc ctgttcttat tcctcctgac taggtaagac ttctcaactt gcctccagcc
     4621 acatcttatt ggtgtgttca gattggcaac aggttcgtac ctcagtggta cagagctccc
     4681 agaggaaggg gtaggctatc atcttccctg gaaaatacga gtcaattagg gacttgaggg
     4741 gacccccagc attccacagc agcccttcag aaaagtggcc agactctgta cttgatgggc
     4801 agatcctcct ggcctgtgtc tctagccagc ccaccactgg agctatcaag ccagtagcaa
     4861 ctcagcagtt ccttggacag agcttccagg agcaaatgaa atcctttctg ccactgcctt
     4921 tgcagtgaac tgcccttgct atcctcagaa gatatatcac gggagcaaag accctaagtg
     4981 ccatatcaac acctccaata agctgcagtt gacccaaaga acaagccaat ccatctccca
     5041 taggtaccac acacactcca ctactcatca ccagacaggg aaccctggct tgggcccaca
     5101 gcacagaccc tccatcctgg gccgattaca ctgagtgatt gctaactcac atgtctctgg
     5161 gatggagcac ccaggagaca agcaaagtgg tggagcagca agtcaggtga tgtggagccc
     5221 agagggcagg gacagctatc tctctaggct ccacttgccc ttgtgagaca ctttgtccca
     5281 gcactttagg aatgctgagg tcagaccagc cacatctcat gtgcaagatt gcccagcaga
     5341 catcaggtct gagagttccc cttttaaaaa aggggacttg cttaaaaaag aagtctagcc
     5401 acgattgtgt agagcagctg tgctgtgctg gagattcact tttgagagag ttctcctctg
     5461 agacctgatc tttagaggct gggcagtctt gcacatgaga tggggctggt ctgatctcag
     5521 cactccttag tctgcttgcc tctcccaggg ccccagcctg gccacacctg cttacagggc
     5581 actctcagat gcccatacca tagtttctgt gctagtggac cgtaccatat cagtggagag
     5641 ctgcagcaag gtggccccta cggccacgca ccagcctgca cattacctct ccatactgca
     5701 gccctttata tggaaacttc ctacatcact ttgctgtgtg tgtttacaca ggtggatttt
     5761 gctttacttg cactgacagc acacaggagg gcagcacaca ccccaaccca catcaactgc
     5821 cattaaagaa aagaaatttc agcccataat ttcatgtcca gcaaaattag gcatcataag
     5881 tgaaggagaa ataagatcct tttcagacaa gcaaatgctg agggaattca atatcaccag
     5941 atctacctta caagagctcc tgaaggaagc actaaatatg gaaagaaaaa accatcacca
     6001 gccactacaa aaatgcagtg aagaacgcag tgaattacgc agtccagtga tgctaaaaac
     6061 caaccacata cgttaagtct gcaaaataac cagctgacag catgacgaca ggataaaatc
     6121 cacacatacc attactaacc ttaaatgaaa atgggctaaa tgctcccatt gaaagacacg
     6181 gggcaagctg gataaagaac caagacccac tggagtatgc tgtcttcaag aaacccatct
     6241 cacatgcggt ggcatacata ggctcaaaat aaaggaatgg agaaaaatat ttcaagcaaa
     6301 tggaaaacag aaaaaagcag gtgttgcact cctactttct gacaaaacag actatgcgaa
     6361 taaagataaa aaagagaagg acattacaaa ggtggtcctg acctttgata aatctcattg
     6421 cttgatacca acctgggctg ttttaattgc ccaaaccaat aggataattt gctgaggttg
     6481 tggagcttct cccctgcaga gagtccctga tctcccaaaa tttggttgag atgtaaggtt
     6541 gattttgctg tacaactcct tttctgaagt tttactcatt tccaaaaagg aaggcaagtt
     6601 ttcctgcttc catgacgatg gagagcaggc atctcctttc ctgagtttca gcttgcttct
     6661 gacagg
//
