LOCUS       NM_001136213            2037 bp    mRNA    linear   PRI 04-JUN-2024
DEFINITION  Homo sapiens POTE ankyrin domain family member H (POTEH), mRNA.
ACCESSION   NM_001136213
VERSION     NM_001136213.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2037)
  AUTHORS   Liu,X., Tang,H., Zhang,Z., Li,W., Wang,Z., Zheng,Y., Wu,M. and
            Li,G.
  TITLE     POTEH hypomethylation, a new epigenetic biomarker for glioma
            prognosis
  JOURNAL   Brain Res 1391, 125-131 (2011)
   PUBMED   21439273
REFERENCE   2  (bases 1 to 2037)
  AUTHORS   Bera,T.K., Huynh,N., Maeda,H., Sathyanarayana,B.K., Lee,B. and
            Pastan,I.
  TITLE     Five POTE paralogs and their splice variants are expressed in human
            prostate and encode proteins of different lengths
  JOURNAL   Gene 337, 45-53 (2004)
   PUBMED   15276201
REFERENCE   3  (bases 1 to 2037)
  AUTHORS   Bera,T.K., Zimonjic,D.B., Popescu,N.C., Sathyanarayana,B.K.,
            Kumar,V., Lee,B. and Pastan,I.
  TITLE     POTE, a highly homologous gene family located on numerous
            chromosomes and expressed in prostate, ovary, testis, placenta, and
            prostate cancer
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16975-16980 (2002)
   PUBMED   12475935
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462]
REFERENCE   4  (bases 1 to 2037)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR545463.2 and AP000529.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000343518.11/ ENSP00000340610.6
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-684               CR545463.2         15383-16066         c
            685-799             AP000529.1         36233-36347         c
            800-973             AP000529.1         35900-36073         c
            974-1080            AP000529.1         32950-33056         c
            1081-1218           AP000529.1         31503-31640         c
            1219-1289           AP000529.1         28962-29032         c
            1290-1360           AP000529.1         23628-23698         c
            1361-1405           AP000529.1         21892-21936         c
            1406-1572           AP000529.1         20684-20850         c
            1573-1691           AP000529.1         11940-12058         c
            1692-2037           AP000529.1         10087-10432         c
FEATURES             Location/Qualifiers
     source          1..2037
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q11.1"
     gene            1..2037
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /note="POTE ankyrin domain family member H"
                     /db_xref="GeneID:23784"
                     /db_xref="HGNC:HGNC:133"
                     /db_xref="MIM:608913"
     exon            1..684
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..1690
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /note="cancer/testis antigen family 104, member 7; actin,
                     beta-like 1; protein expressed in prostate, ovary, testis,
                     and placenta 22; protein expressed in prostate, ovary,
                     testis, and placenta POTE14 like; ANKRD26-like family C
                     member 3; prostate, ovary, testis-expressed protein on
                     chromosome 22"
                     /codon_start=1
                     /product="POTE ankyrin domain family member H"
                     /protein_id="NP_001129685.1"
                     /db_xref="CCDS:CCDS74808.1"
                     /db_xref="GeneID:23784"
                     /db_xref="HGNC:HGNC:133"
                     /db_xref="MIM:608913"
                     /translation="MVAEAGSMPAASSVKKPFGLRSKMGKWCRHCFAWCRGSGKSNVG
                     TSGDHDDSAMKTLRSKMGKWCCHCFPWCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWC
                     CHCFPCCRGSGKSNVGTSGDHDDSAMKTLRSKMGKWCCHCFPCCRGSGKNKVGPWGDY
                     DDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVMLKDTDMNKKDKQKRTALHLAS
                     ANGNSEVVKLLLDRRCQLNILDNKKRTALTKAVQCQEDECALMLLEHGTDPNIPDEYG
                     NTALHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKAN
                     LNALDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSRHNVICQ
                     LLSDYKEKQILKVSSENSNPEQDLKLTSEEESQRLKGSENSQPEEMSQEPEINKGGDR
                     KVEEEMKKHGSTHMGFPENLTNGATADNGDDGLIPPRKSRTPESQQFPDTENEQYHSD
                     EQNDTQKQLSEEQNTGILQDEILIHEEKQIEVAENEF"
     exon            685..799
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            800..973
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1080
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1218
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1289
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1360
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..1405
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1572
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1691
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
     exon            1692..2037
                     /gene="POTEH"
                     /gene_synonym="A26C3; ACTBL1; CT104.7; POTE22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtagacgcg atctgctggc tactaccggc cttccctggc tgttaaaagc agatggtggc
       61 tgaggctggt tcaatgccgg ctgcctcctc tgtgaagaag ccatttggtc tcagaagcaa
      121 gatgggcaag tggtgccgcc actgcttcgc ctggtgcagg gggagcggca agagcaacgt
      181 gggcacttct ggagaccacg acgattctgc tatgaagaca ctcaggagca agatgggcaa
      241 gtggtgctgc cactgcttcc cctggtgcag ggggagcggc aagagcaacg tgggcacttc
      301 tggagaccac gacgattctg ctatgaagac actcaggagc aagatgggca agtggtgctg
      361 ccactgcttc ccctgctgca gggggagcgg caagagcaac gtgggcactt ctggagacca
      421 cgacgactct gctatgaaga cactcaggag caagatgggc aagtggtgct gccactgctt
      481 cccctgctgc agggggagcg gcaagaacaa agtgggccct tggggagact acgacgacag
      541 cgctttcatg gagccgaggt accacgtccg tcgagaagat ctggacaagc tccacagagc
      601 tgcctggtgg ggtaaagtcc ccagaaagga tctcatcgtc atgctcaagg acactgacat
      661 gaacaagaag gacaagcaaa agaggactgc tctacatctg gcctctgcca atggaaattc
      721 agaagtagta aaactcctgc tggacagacg atgtcaactt aatatccttg acaacaaaaa
      781 gaggacagct ctgacaaagg ccgtacaatg ccaggaagat gaatgtgcgt taatgttgct
      841 ggaacatggc actgatccga atattccaga tgagtatgga aataccgctc tacactatgc
      901 tatctacaat gaagataaat taatggccaa agcactgctc ttatacggtg ctgatatcga
      961 atcaaaaaac aagcatggcc tcacaccact gttacttggt gtacatgagc aaaaacagca
     1021 agtggtgaaa tttttaatca agaaaaaagc aaatttaaat gcactggata gatatggaag
     1081 aactgctctc atacttgctg tatgttgtgg atcggcaagt atagtcagcc ttctacttga
     1141 gcaaaacatt gatgtatctt ctcaagatct atctggacag acggccagag agtatgctgt
     1201 ttctagtcgt cataatgtaa tttgccagtt actttctgac tacaaagaaa aacagatact
     1261 aaaagtctct tctgaaaaca gcaatccaga acaagactta aagctgacat cagaggaaga
     1321 gtcacaaagg cttaaaggaa gtgaaaatag ccagccagag gaaatgtctc aagaaccaga
     1381 aataaataag ggtggtgata gaaaggttga agaagaaatg aagaagcacg gaagtactca
     1441 tatgggattc ccagaaaacc tgactaacgg tgccactgct gacaatggtg atgatggatt
     1501 aattccacca aggaaaagca gaacacctga aagccagcaa tttcctgaca ctgagaatga
     1561 acagtatcac agtgatgaac aaaatgatac tcagaagcaa ctttctgaag aacagaacac
     1621 tggaatatta caagatgaga ttctgattca tgaagaaaag cagatagaag tggctgaaaa
     1681 tgaattctga gctttctctt agttataaga aagaaaaaga cctcttgcat gaaaatagta
     1741 cgttgcagga agaaattgtc atgctaagac tggaactaga cataatgaaa catcagagcc
     1801 agctaagaga aaagaaatat ttggaggaaa ttgaaagtgt ggaaaaaaag aatgataatc
     1861 ttttaaaggg tctacaactg aatgagctca ccatggatga tgatactgcc gtgctcgtca
     1921 ttgacaacgg ctctggcatg tgcaaggccg gctttgcagg tgacgatgcc ccccgggctg
     1981 tcttcccttc catcgtgggg tgccccaggc accagaacat gatggggggc atgcgtc
//
