LOCUS       NM_001137671            6642 bp    mRNA    linear   PRI 10-JUN-2024
DEFINITION  Homo sapiens POTE ankyrin domain family member C (POTEC),
            transcript variant 1, mRNA.
ACCESSION   NM_001137671 XM_496269
VERSION     NM_001137671.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6642)
  AUTHORS   Bera,T.K., Zimonjic,D.B., Popescu,N.C., Sathyanarayana,B.K.,
            Kumar,V., Lee,B. and Pastan,I.
  TITLE     POTE, a highly homologous gene family located on numerous
            chromosomes and expressed in prostate, ovary, testis, placenta, and
            prostate cancer
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16975-16980 (2002)
   PUBMED   12475935
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP006261.1.
            
            On Aug 13, 2020 this sequence version replaced NM_001137671.1.
            
            Transcript Variant: This variant (1) encodes the functional
            protein.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2158188
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000358970.10/ ENSP00000351856.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-975               AP006261.1         153222-154196       c
            976-1090            AP006261.1         148731-148845       c
            1091-1264           AP006261.1         148397-148570       c
            1265-1371           AP006261.1         145497-145603       c
            1372-1509           AP006261.1         143657-143794       c
            1510-1580           AP006261.1         141079-141149       c
            1581-1651           AP006261.1         135509-135579       c
            1652-1696           AP006261.1         134059-134103       c
            1697-1863           AP006261.1         132850-133016       c
            1864-1987           AP006261.1         124258-124381       c
            1988-2243           AP006261.1         122334-122589       c
            2244-6642           AP006261.1         117935-122333       c
FEATURES             Location/Qualifiers
     source          1..6642
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18p11.21"
     gene            1..6642
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /note="POTE ankyrin domain family member C"
                     /db_xref="GeneID:388468"
                     /db_xref="HGNC:HGNC:33894"
     exon            1..975
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     CDS             455..2083
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /note="isoform 1 is encoded by transcript variant 1;
                     cancer/testis antigen family 104, member 6; ANKRD26-like
                     family B member 2; prostate, ovary, testis-expressed
                     protein on chromosome 18"
                     /codon_start=1
                     /product="POTE ankyrin domain family member C isoform 1"
                     /protein_id="NP_001131143.1"
                     /db_xref="CCDS:CCDS45835.1"
                     /db_xref="GeneID:388468"
                     /db_xref="HGNC:HGNC:33894"
                     /translation="MVTEVCSMPAASAVKKPFDLRSKMGKWFHHRFPCCKGSGKSNMG
                     TSGDHDDSFMKMLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWC
                     CHCFPCCRGSGKSNVGAWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVM
                     LRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQE
                     DECVLMLLEHGADQNIPDEYGNTTLHYAVHNEDKLMAKALLLYGADIESKNKCGLTPL
                     LLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQ
                     DLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKV
                     SENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQR
                     RSRKPENQQFPDTENEEYHSDEQNDTRKQLSEEQNTGISQDEILTNKQKQIEVAEKKM
                     NSELSLSHKKEEDLLRENSMLQEEIAMLISGDWN"
     exon            976..1090
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1264
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1371
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1509
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1510..1580
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1581..1651
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1652..1696
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1863
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1864..1987
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
     exon            1988..6642
                     /gene="POTEC"
                     /gene_synonym="A26B2; CT104.6; POTE-18; POTE18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ataacggctt ggcttacctg taacgggtac gcttcgcttt gcgttcctcg cttggccttg
       61 cgttcctagc ttggcttggc gttagtcgct ttgcctggtg tttcttgctt ggattggcgt
      121 ttcctccctc gcattccttt gctgggcttg actttttctc tgctgggttt ggcattccct
      181 tgactgggct gggtgtttcc ttgggagggg gggcttggcc tttcctgggg tgggcgttgg
      241 gtccccctgg tgggcgtggg ctttccccgg gtgggtgtgg gttttccctg ggtggggtgg
      301 actgggctcc cttgctgggg ttggcaagtt ttggctggga ttgacctttc tcttcaaaca
      361 gattggaaac ccagggtttc ctgctagttg gtgaaactgg ttggtagacg cgatctgttc
      421 gctactaccg gcctccccgg gctgttaaaa gcagatggtg actgaggttt gttcaatgcc
      481 cgctgcctct gctgtgaaga agccattcga tctcaggagc aagatgggca agtggtttca
      541 ccaccgcttc ccctgctgca aggggagcgg caagagcaac atgggcactt ctggagacca
      601 cgacgactcc tttatgaaga tgctcaggag caagatgggc aagtgttgcc accactgctt
      661 cccctgctgc agggggagcg gcacgagcaa cgtgggcact tctggagacc atgacaactc
      721 ctttatgaag acgctcagga gcaagatggg caagtggtgc tgtcactgct tcccctgctg
      781 cagggggagc ggcaagagca acgtgggcgc ttggggagac tacgacgaca gcgccttcat
      841 ggagccgagg taccacgtcc gtcgagaaga tctggacaag ctccacagag ctgcctggtg
      901 gggtaaggtc cccagaaagg atctcatcgt catgctcagg gacacggaca tgaacaagag
      961 ggacaagcaa aagaggactg ctctacattt ggcctctgcc aatggaaatt cagaagtagt
     1021 acaactcctg ctggacagac gatgtcaact taatgtcctt gacaacaaaa aaaggacagc
     1081 tctgataaag gccgtacaat gccaggaaga tgaatgtgtg ttaatgttgc tggaacatgg
     1141 cgctgatcaa aatattccag atgagtatgg aaataccact ctacactatg ctgtccacaa
     1201 tgaagataaa ttaatggcca aagcactgct cttatatggt gctgatattg aatcaaaaaa
     1261 caagtgtggc ctcacaccac ttttgcttgg cgtacatgaa caaaaacagc aagtggtgaa
     1321 atttttaatc aagaaaaaag ctaatttaaa tgcacttgat agatatggaa gaactgccct
     1381 catacttgct gtatgttgtg gatcagcaag tatagtcaat cttctccttg agcaaaatgt
     1441 tgatgtatct tctcaagatc tatctggaca gacggccaga gagtatgctg tttctagtca
     1501 tcatcatgta atttgtgaat tactttctga ctataaagaa aaacagatgc taaaaatctc
     1561 ttctgaaaac agcaatccag aacaagactt aaagctaaca tcagaggaag agtcacaaag
     1621 gcttaaagtc agtgaaaata gccagccaga gaaaatgtct caagaaccag aaataaataa
     1681 ggactgtgat agagaggttg aagaagaaat aaagaagcat ggaagtaatc ctgtgggatt
     1741 accagaaaac ctgactaatg gtgccagtgc tggcaatggt gatgatggat taattccaca
     1801 aaggaggagc agaaaacctg aaaatcagca atttcctgac actgagaatg aagagtatca
     1861 cagtgacgaa caaaatgata cccggaaaca actttctgaa gaacagaaca ctggaatatc
     1921 acaagatgag attctgacta ataaacaaaa gcagatagaa gtggctgaaa agaaaatgaa
     1981 ttctgagctt tctcttagtc ataagaaaga agaagatctc ttgcgtgaaa acagcatgtt
     2041 gcaggaagaa attgccatgc taatttctgg agactggaac tagatgaaac aaaacatcag
     2101 aaccagctaa gggaaaataa aattttggag gaaattgaaa gtgtgaaaga aaagactgat
     2161 aaacttctaa gggctatgca attgaatgaa gaagcattaa cgaaaaccaa tatttaagta
     2221 cagtggacag cttaggattt tgacaactga gaatgctcag ttctgaactg gagaatgtaa
     2281 gacacagcta ggaaacactg gaaatggaaa ttcaatcatg tcattgtaga ctgactactg
     2341 ctctacatga ttgtgatcaa agtcagatag ctgaaaggga cttctttcca gagaacaaac
     2401 atgaacaggt ttatttacag gagaaaatga attctcatat atctcaccta aaagataaca
     2461 gtgagattct ttctgaacaa ctctaacgct gacagtaaaa ttaacaacct aaaaattaag
     2521 ctccatcaca caggataaat tctgagagaa aagatgaggc aggccaccat ctttcctgtt
     2581 tgggcaactt agcgattcca gcgtgcgggc tttggagagt acaaacccac caggggcaga
     2641 agagatcctg tggcatagca cagctgcttt accaaatcat gtccagaatg cttctgtaag
     2701 caggcctctg atcctgttcc tcgtcactgg acaggatctc ccacctgagg cctccagcta
     2761 cacccaccag tgttccctgg ccaatggaga tttgaaacct tcctgggaca gagttcccag
     2821 agagaggggt gggccatgac ctttgttgtt tgggcaacta gcccttctgg cctgtgggct
     2881 ttggagagcc caagctgacc aggggtggaa gtggtacctc agcacagaac agccaccctg
     2941 cgaaaacgtg gccagattct tgtttaagcc agtccccaac cacatttcta atcactgggt
     3001 ggagcctttc aaccagggtc tccagccacc ttcactgctg ttctctggct cacagaggtt
     3061 tcaggcctcc tgagtcagag ctcccagggg gaggaccaga ctgtcatctt tgctgtttgg
     3121 atgactcagc cagttcagtc ttagagtttc agagtgtctg aggagaccag gggctgaagt
     3181 gaacccccca cacagcatag ccactctaca aaaacgtggc cagacttctt ttttaaacaa
     3241 gtccctattc ctgttcctcc ttactaggca agacttctca acttgcttcc agtcacatcc
     3301 tacaggtgtg ttgagattgg caacaggttc atacctcaga ggtacagagc tcccagaggg
     3361 aagggcaggc tatcgtcttt gctttttctc aggcttcact gctgatacct tcagccactg
     3421 gaaaatacga ggcaattggc gactggagtg gacccccagc ataccacggc agccccacag
     3481 aaaagtggcc agactgttat gtgggtgccc atttccatat ctcctcgatg ggcaggtctt
     3541 cctggcctgg gtctccagcc agccccccac ttgagctttc aagccagtag caactcagca
     3601 actccctgga cagagcttcc aggagcaaca gaaatcctct ctgccactgc ctctgcagtg
     3661 gaactgccct tgctaccctc agaatatcaa gggagcaaag accctaagtg ccatattgac
     3721 acctccaaca agctgcagtt gacacaagga acaagtcagt ccatcttcca caggtacaac
     3781 acacccctta ctgctcatca ccagacaagg aaccgtggct tgggcccaca acacagaccc
     3841 tccatcctgg ggtgattaca ttaagtaact gctaacttac acctctctgg ggtggagccc
     3901 ccaggagaca aggaaagtag tggagcagca agtcagctga tgtggagcct ggagggcagg
     3961 gacagctatg tctctaggct ccacttgctc ttatgagaca ctttatccca gcactttagg
     4021 agtgctgagg tcagaccagc cccatctcac gtgcaagatt gcccagcaca gatcaggtct
     4081 aagagttctc ttcgtaaaaa aggggacttg cttaaaaaag aagtctggcc acgtttgtgt
     4141 agagcagttg tgctgtgctg aggattcact tttgagagag ttctcctctg agacctgatc
     4201 tgtgctgggc agtcttgcac atgagatggg gctggtctga cctcagcacc ccttagtctg
     4261 cttgcctctc ccaggacccc agccaggcca cacctgctta gagggcactt tcgggtgccc
     4321 acaccatagc ttctgtacaa gcggaccgtg cctgatcagt ggagagctgc agcaaggtga
     4381 cctctacagc cacgcactag cctgcacatt accattccat actgcagccc tttatatgga
     4441 aacttcctac atcactttgc tgtgtgtgtt tacacaggtg ggttttgttg tacttgccct
     4501 aacagcatat gggaatgcag cacacacccc aacccacacc aactgccact gaagatgaag
     4561 ccatggtggg cacagaacca aaaaccccac ccctgctagc atctcaccct tgaggtaatg
     4621 ctgtgcagag gaaaagggac cttcttatac cctgagtgac cactgttgct tgggggggat
     4681 cagagaaggc accttcactg gccagccacc caccccaaac cagcactacc tccagtgcaa
     4741 cagcacacac agtcagcagg ggcccgtggc ccacacccca gctgttttgc ctccaccact
     4801 gggtgaatgc ccacagggag gcagggactt ttgcatctgc tagcattctg ccacagctgc
     4861 tgcactttgg tcccctcagt gcagtggact ccaaacctcg aggagccaga ggacaaagtt
     4921 gtggcccaat acaagttccc cagagttaaa gcacacagtc caagaattgg gagctgcatg
     4981 ttggcccctt aaaatcctcc aaaaacaaaa cctgttggct gaatccacct tacaccacaa
     5041 tcaaatcctc aaggtcatca gatataataa aggaaaaata ccctgtccaa aggtcagcaa
     5101 cctcaaagat tgaagatgga taagcccata aagatgagaa aaagactctg tgcaagaaca
     5161 ctgaaaactc aaaaattcag cataccttct tttctccaaa tgactgcatc aactctccag
     5221 caagtgttca gaactgggct gaggctgaga tgtctgaaat gatacaagca gagttcagga
     5281 tatgggtagg aacaaagttc attgagtgaa agaagtatgt tgtaatccaa tacaaggaag
     5341 ctaaaaatca ttgtaaaaca ttgcaggaac taacagacaa aatagtgagt ataaagaaga
     5401 aaataactga cctgacagag ctgtaaatca cactagaaga attttcataa tgtagtcaca
     5461 tggtgattgt gtgtgattgc attatgaata ttattgtagt atgtgtgggc acctgagagt
     5521 gccctgtaag caggtgtggc caggctgggg tcctgggaga ggcaagcaga ctagggaggg
     5581 ctgaggtcag accagctcca tctcatgtgc aagaccatct aacagaatag accaagaaga
     5641 ggaaagaatc ccagagcttg aaaactggct ttctgaaata aaacaggcaa acaagaatgg
     5701 gggaaaaaag aatgaaaggg aatgaacaaa acatccgaga aatatgggat tatataaacg
     5761 accaaatcta tgactgatta atgtacctga aagagatgag gagaatggaa ccaacttgga
     5821 aaacacattt cagaatatca ttcatgagaa tgtccccaac ctagccagac aggccaacat
     5881 tcaacttcag gaaatccaga gaacctcagt aagatatgcc atgagaagat catccccaag
     5941 acacataatc atcagattct ctgaggtcaa aataaaagaa aaaatgttaa aggcagctag
     6001 ggagaaaggc aacatcacct gcaaagggaa ttccatcaga cttagcagac ctctcaactg
     6061 aaactgtaca agccagaaaa gacattcaac atttcaaaga aaagaaattt caacccagaa
     6121 tttcatgtcc agcaaaatta agcatcataa gtgaaggaga aacaagatcg ttttcagaca
     6181 agcaaatgct gagggaattc gttatcacca gacctacctt acaagagctc ctgaaggaag
     6241 cactaaatat ggaaagaaaa gaccaccacc agccactaca aaaacacact gaagtacaca
     6301 gacaagtgat gctaaaaacc aaccacatac ataagtctgc aaaagagcca gctgacagca
     6361 tgatgacagg atcaaatcca cacataccat tactaacctt aaatggaaat gggctaaatg
     6421 ctccaattga aagacacagg gggcaagctg gataaagaac caagacccat tggagtatgc
     6481 cgtcttcaag aaacccatct cacatgcagt gccatacata ggctcaaaat aaaggaatgg
     6541 agaaaaatat ttcaaggaaa tggaaaacag aaaaaagcag gtgttgcact cctagtttct
     6601 gacaaaacag actataccaa taaagattta aaaaaaaaaa aa
//
