LOCUS       NM_207355               5816 bp    mRNA    linear   PRI 03-OCT-2024
DEFINITION  Homo sapiens POTE ankyrin domain family member B3 (POTEB3),
            transcript variant 1, mRNA.
ACCESSION   NM_207355 XM_006720357
VERSION     NM_207355.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5816)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 5816)
  AUTHORS   Alkan,C., Kidd,J.M., Marques-Bonet,T., Aksay,G., Antonacci,F.,
            Hormozdiari,F., Kitzman,J.O., Baker,C., Malig,M., Mutlu,O.,
            Sahinalp,S.C., Gibbs,R.A. and Eichler,E.E.
  TITLE     Personalized copy number and segmental duplication maps using
            next-generation sequencing
  JOURNAL   Nat Genet 41 (10), 1061-1067 (2009)
   PUBMED   19718026
REFERENCE   3  (bases 1 to 5816)
  AUTHORS   Zody,M.C., Garber,M., Sharpe,T., Young,S.K., Rowen,L., O'Neill,K.,
            Whittaker,C.A., Kamal,M., Chang,J.L., Cuomo,C.A., Dewar,K.,
            FitzGerald,M.G., Kodira,C.D., Madan,A., Qin,S., Yang,X., Abbasi,N.,
            Abouelleil,A., Arachchi,H.M., Baradarani,L., Birditt,B., Bloom,S.,
            Bloom,T., Borowsky,M.L., Burke,J., Butler,J., Cook,A.,
            DeArellano,K., DeCaprio,D., Dorris,L. 3rd, Dors,M., Eichler,E.E.,
            Engels,R., Fahey,J., Fleetwood,P., Friedman,C., Gearin,G.,
            Hall,J.L., Hensley,G., Johnson,E., Jones,C., Kamat,A., Kaur,A.,
            Locke,D.P., Madan,A., Munson,G., Jaffe,D.B., Lui,A., Macdonald,P.,
            Mauceli,E., Naylor,J.W., Nesbitt,R., Nicol,R., O'Leary,S.B.,
            Ratcliffe,A., Rounsley,S., She,X., Sneddon,K.M., Stewart,S.,
            Sougnez,C., Stone,S.M., Topham,K., Vincent,D., Wang,S.,
            Zimmer,A.R., Birren,B.W., Hood,L., Lander,E.S. and Nusbaum,C.
  TITLE     Analysis of the DNA sequence and duplication history of human
            chromosome 15
  JOURNAL   Nature 440 (7084), 671-675 (2006)
   PUBMED   16572171
REFERENCE   4  (bases 1 to 5816)
  AUTHORS   Bera,T.K., Huynh,N., Maeda,H., Sathyanarayana,B.K., Lee,B. and
            Pastan,I.
  TITLE     Five POTE paralogs and their splice variants are expressed in human
            prostate and encode proteins of different lengths
  JOURNAL   Gene 337, 45-53 (2004)
   PUBMED   15276201
REFERENCE   5  (bases 1 to 5816)
  AUTHORS   Bera,T.K., Zimonjic,D.B., Popescu,N.C., Sathyanarayana,B.K.,
            Kumar,V., Lee,B. and Pastan,I.
  TITLE     POTE, a highly homologous gene family located on numerous
            chromosomes and expressed in prostate, ovary, testis, placenta, and
            prostate cancer
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16975-16980 (2002)
   PUBMED   12475935
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC060814.11.
            
            On Jan 1, 2020 this sequence version replaced NM_207355.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the supported protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY465173.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968968,
                                           SAMEA2148093 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000611217.5/ ENSP00000483103.1
            RefSeq Select criteria :: based on longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1009              AC060814.11        57858-58866
            1010-1124           AC060814.11        63249-63363
            1125-1298           AC060814.11        63523-63696
            1299-1405           AC060814.11        66512-66618
            1406-1543           AC060814.11        67956-68093
            1544-1614           AC060814.11        70602-70672
            1615-1685           AC060814.11        76167-76237
            1686-1730           AC060814.11        77639-77683
            1731-1897           AC060814.11        78727-78893
            1898-2021           AC060814.11        87356-87479
            2022-5816           AC060814.11        89162-92956
FEATURES             Location/Qualifiers
     source          1..5816
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q11.2"
     gene            1..5816
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /note="POTE ankyrin domain family member B3"
                     /db_xref="GeneID:102724631"
                     /db_xref="HGNC:HGNC:51240"
     exon            1..1009
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     CDS             489..2234
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /note="ANKRD26-like family B member 1; prostate, ovary,
                     testis-expressed protein on chromosome 15; POTE ankyrin
                     domain family member B; POTE ankyrin domain family, member
                     B-like"
                     /codon_start=1
                     /product="POTE ankyrin domain family member B3"
                     /protein_id="NP_997238.2"
                     /db_xref="CCDS:CCDS73690.1"
                     /db_xref="GeneID:102724631"
                     /db_xref="HGNC:HGNC:51240"
                     /translation="MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGKSNMG
                     TSGDHDDSFMKTLRSKMGKCCHHCFPCCRGSGTSNVGTSGDHDNSFMKTLRSKMGKWC
                     CHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRREDLDKLHRAAWWGKVPRKDLIVM
                     LRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRCQLNVLDNKKRTALIKAVQCQE
                     DECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMAKALLLYGADIESKNKCGLTPL
                     LLGVHEQKQQVVKFLIKKKANLNALDRYGRTALILAVCCGSASIVNLLLEQNVDVSSQ
                     DLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSENSNPEQDLKLTSEEESQRLKV
                     SENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGLPENLTNGASAGNGDDGLIPQR
                     KSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTGISQDEILTNKQKQIEVAEKEM
                     NSKLSLSHKKEEDLLRENSMLREEIAMLRLELDETKHQNQLRENKILEEIESVKEKLL
                     KAIQLNEEALTKTSI"
     exon            1010..1124
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1298
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1405
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1543
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1544..1614
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1685
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1686..1730
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1731..1897
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1898..2021
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..5816
                     /gene="POTEB3"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcgcgcc ccgcacgcgc gccccgcacg cgcataacgg cttggcttac ctgtaacggg
       61 tacacttcgc ttcgcgttcc tcgcttggcc ttgcgttcct agcttggctt ggctgttagt
      121 agctttgcct ggtgtttctt gcttggattg gcgtttcctc cctcgcattc ctttgctgga
      181 cttgaccttt tctctgctgg gtttggcatt cccttgactg ggctgggtgt ttccttggga
      241 gggggggctt ggcctttcct ggggtgggcg tggggtcccc ctggtgggcg tgggctttcc
      301 ccgggtgggt gtgggttttc cctgggtggg gtgggctggg ctcccttgct gggcttggca
      361 agttttggct gggattgacc tttctcttca aacagattgg aaacccaggg tttcctgcta
      421 gttggtgaaa ctggttggta gacgcgatct gttcgctact accggcctcc cctggctgtt
      481 aaaagcagat ggtggctgag gtttgttcaa tgcccgctgc ctctgctgtg aagaagccat
      541 ttgatctcag gagcaagatg ggcaagtggt gccaccaccg cttcccctgc tgcaggggga
      601 gcggcaagag caacatgggc acttctggag accacgacga ctcctttatg aagacgctca
      661 ggagcaagat gggcaagtgt tgccaccact gcttcccctg ctgcaggggg agcggcacga
      721 gcaatgtggg cacttctgga gaccatgaca actcctttat gaagacactc aggagcaaga
      781 tgggcaagtg gtgctgtcac tgcttcccct gctgcagggg gagcggcaag agcaacgtgg
      841 gcacttgggg agactacgac gacagcgcct tcatggagcc gaggtaccac gtccgtcgag
      901 aagatctgga caagctccac agagctgcct ggtggggtaa agtccccaga aaggatctca
      961 tcgtcatgct cagggacact gacatgaaca agagggacaa gcaaaagagg actgctctac
     1021 atttggcctc tgccaatgga aattcagaag tagtacaact cctgctggac agacgatgtc
     1081 aacttaacgt ccttgacaac aaaaaaagga cagctctgat aaaggccgta caatgccagg
     1141 aagatgaatg tgtgttaatg ttgctggaac atggcgctga tggaaatatt caagatgagt
     1201 atggaaatac cgctctacac tatgctatct acaatgaaga taaattaatg gccaaagcac
     1261 tgctcttata tggtgctgat attgaatcaa aaaacaagtg tggcctcaca ccacttttgc
     1321 ttggcgtaca tgaacaaaaa cagcaagtgg tgaaattttt aatcaagaaa aaagctaatt
     1381 taaatgcact tgatagatat ggaagaactg ccctcatact tgctgtatgt tgtggatcag
     1441 caagtatagt caatcttcta cttgagcaaa atgttgatgt atcttctcaa gatctatctg
     1501 gacagacggc cagagagtat gctgtttcta gtcatcatca tgtaatttgt gaattacttt
     1561 ctgactataa agaaaaacag atgctaaaaa tctcttctga aaacagcaat ccagaacaag
     1621 acttaaagct gacatcagag gaagagtcac aaaggcttaa agtcagtgaa aatagccagc
     1681 cagagaaaat gtctcaagaa ccagaaataa ataaggactg tgatagagag gttgaagaag
     1741 aaataaagaa gcatggaagt aatcctgtgg gattaccaga aaacctgact aatggtgcca
     1801 gtgctggcaa tggtgatgat ggattaattc cacaaaggaa gagcagaaaa cctgaaaatc
     1861 agcaatttcc tgacactgag aatgaagagt atcacagtga cgaacaaaat gatacccaga
     1921 aacaactttc tgaagaacag aacactggaa tatcacaaga tgagattctg actaataaac
     1981 aaaagcagat agaagtggct gaaaaggaaa tgaattctaa gctttctctt agtcataaga
     2041 aagaagaaga tctcttgcgt gaaaacagca tgttgcggga agaaattgcc atgctaagac
     2101 tggaactaga tgaaacaaaa catcagaacc agctaaggga aaataaaatt ttggaggaaa
     2161 ttgaaagtgt aaaagaaaaa cttctaaagg ctatacaact gaatgaagaa gcattaacga
     2221 aaaccagtat ttaagtacag tggacagctt aggattttga caactgagaa tgctcagttc
     2281 tgaactggag aatgtaagac acagctagga aacactggaa atggaaattc aatcatgtca
     2341 ttgtagactg actactgctc tacatgattg tgatcaaagt cagatagctg aaagggactt
     2401 ctttccagag aacaaacatc aacaggttta tttacaggag aaaatgaatt cttatatatc
     2461 tcacctaaaa gataacagtg agattctttc tgaacaactc taacgctgac agtaaaatta
     2521 acaacctaaa aattaagctc catcacacag gataaattct gagagaaaag atgaggcagg
     2581 ccaccatctt tcctgtttgg gcaacttagt cattccagcg tgcgggcttt ggagagtaca
     2641 aactcaccag ggacagaaga gatcctgtgg catagcacag ctgctttacc aaatcatggc
     2701 cagaatgctt ctgtaagcag gcccctgatc ctgttcctcg tcactggaca ggatctccca
     2761 cctgaggcct ccagctacac ccaccagtgt tccctggcca atggagattt gaaaccttcc
     2821 tgggacagag ttcccagaga gaggggtggg ccatgatggg caggtcttcc tggcctgggt
     2881 ctccagccag ccccccactt gagccttcaa gccagtagca actcagcaac tccctggaca
     2941 gagcttccag gagcaacaga aatcctctct gccactgcct ctgcagtgga actgcccttg
     3001 ctaccctcag aatgtcaagg gagcaaagac cctaagtgcc atattgacac ctccaacaag
     3061 ctgcagttga cacaaggaac aagtcagtcc atcttccacg ggtacaacac accccttact
     3121 gctcatcaac agacaaggaa ccctggcttg ggcccacagc acagaccctc catcctgggg
     3181 tgattacatt aagtaactcc taacttacac ctctctgggg tgtagccccc aggagacaag
     3241 gaaagtggtg gagcagcaag tcagctgatg tggagcctgg agggcaggga catctatgtc
     3301 tctaggctcc acttgctctt atgagacact ttatcccagc acttaaggag tgctgaggtc
     3361 agaccagccc catctcacgt gcaagattgc ccagcacaga tcaggtctaa gagttctctt
     3421 cctaaaaagg gggacttgct taaaaaagaa gtctggccgc gtttgtgtag agcagttgtg
     3481 ctgtgctgag gattcacttt tgagagagtt ctcctctgag acctgatctc tgctgggcag
     3541 tcttgcacat gagatggggc tggtctgacc tcagcacccc ttagtctgct tgcctctccc
     3601 aggaccccag ccaggccaca cctgcttaga gggcactttt gggtgcccac accatagctt
     3661 ctgtacaagc agaccgtggc tgatcagtgg agagctgcag caaggtgacc tctacagcca
     3721 cgtaccagcc tgcacattac ctctccatac tgcagccctt tatatggaaa cttcctacat
     3781 cacttagctg tgtgtgttta cacaggtggg ttttgttgta cttgccctaa cagcatatgg
     3841 gaatgcagca cacaccccaa cccacaccaa ctgccactga agatgaagcc atggtgggca
     3901 cagaaccaaa aaccccaccc ctgctagcat ctcacccttg aggtaatgct gtgcagagga
     3961 aaagggacct tcttataccc tgagtgacca ctgttgcttg ggggggatca gagaaggcac
     4021 cttcactggc cagccaccca ccccaaacca gaactacctc cagtgcaaca gcacacacag
     4081 tcagcagggg ccccctggcc cacaccccag ctgttttgcc tccaccacta ggtgaatgcc
     4141 cacagggagg cagggacttt tgcatctgct agcattctgc cacagctgcc acactttggt
     4201 cccctcagtg cggtggactc caaacctcga tgagccagag aacaaagttg tggcccaata
     4261 caagttcccc agagttaaag cacacagtcc aagaattggg agctgcatgt tggcccctta
     4321 aaatcctcca aagacaaaac ctgttggctg aatccacctt acaccacaat caaatcctca
     4381 aggtcatcag atataataaa ggaaaaatac cctgtccaaa ggtcagcagc ctcaaagatt
     4441 gaaggtggat aagcccataa agatgagaaa aagactctgt gcaagaacac tgaaaactca
     4501 aaaattcagc atgctttctt ttctccaaat gactgcatca actctccagc aagtgttcag
     4561 aactgggctg aggctgagat gtctgaaatg atacaagcag agttcaggat atgggtagga
     4621 acaaagttcc ctgagtgaaa gaagtatgtt gtaatccaat acaaggaagc taaaaatcat
     4681 tgtaaaacat tgcaggaact aacagacaaa atagcaagta taaagaagaa aataactgac
     4741 ctgacagagc tgtaaatcac actagaagaa ttttcataat gcagtcacac ggtgattgtg
     4801 tgtgattgca ttatgaaaat tattgtagta tgtgtgggca cctgagagtg ccctgtaagc
     4861 agatgtggcc aggctggggt cctgggagag gcaagcagac tagggagggc tgaggtcaga
     4921 ccagctccat ctcatgtgca agaccatcca acagaataga ccaagaagag gaaagaatcc
     4981 cagaatctgg aaactggctt tctgaaataa aacaggcaaa caagaatggg ggaaaaaaga
     5041 atgaaaggga atgaacaaaa catccgagaa atatgggatt atataaacga ctaaatctat
     5101 gactgattaa tgtacctgaa agagatgagg agaatggaac caacttggaa aacacatttc
     5161 agaatatcat tcatgagaat gtccccaacc tagccagaca ggccaacact caacttcagg
     5221 aaatccagag aacctcagta agatatgcca tgagaagatc atccccaaga cacataatca
     5281 tcagattctc tgcggtcaaa atgaaagaaa aagtgttaaa ggcagctagg gagaaaggca
     5341 acatcacctg caaagggaat tccatcagac ttagcagacc tctcaactga aactgtacaa
     5401 gccagaaaag atattcaaca tcttaaagaa aagaaatttc aacccggaat ttcatgtcca
     5461 gcaaaattaa gcatcataag tgaaggagaa acaagatcct tttcaggcaa gcaaatgctg
     5521 agggaattca ttatcaccag acctacctta caagagctcc tgaaggaagc actaaatatg
     5581 gaaagaaaag accaccacca gccactacaa aaacacactg aagtacacag acaagtgatg
     5641 ctaaaaacca accacataca taagtctgca aaaaagccag ctgacagcat gacgagagga
     5701 tcaaatccac acataccatt actaacctta aatggaaatg ggctaaatgc tccaattgaa
     5761 agacacaggg ggcaagctgg ataaagaacc aagacccatt ggagtatgcc gtcttc
//
