LOCUS       NM_001277303            1687 bp    mRNA    linear   PRI 03-APR-2024
DEFINITION  Homo sapiens POTE ankyrin domain family member B2 (POTEB2),
            transcript variant 1, mRNA.
ACCESSION   NM_001277303 XM_002343312
VERSION     NM_001277303.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1687)
  AUTHORS   Bera,T.K., Zimonjic,D.B., Popescu,N.C., Sathyanarayana,B.K.,
            Kumar,V., Lee,B. and Pastan,I.
  TITLE     POTE, a highly homologous gene family located on numerous
            chromosomes and expressed in prostate, ovary, testis, placenta, and
            prostate cancer
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16975-16980 (2002)
   PUBMED   12475935
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC101007.1 and AC012414.12.
            
            On Mar 28, 2013 this sequence version replaced XM_002343312.5.
            
            Transcript Variant: This variant (1) represents the longer variant
            and encodes the supported protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on paralogous transcript alignments.
            
            CCDS Note: The exon combination of this CCDS representation is
            inferred based on highly similar paralogous transcript alignments,
            e.g., AY465170.1 or BC101005.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968968, SAMEA2148093
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000454856.4/ ENSP00000456953.1
            RefSeq Select criteria    :: based on conservation, expression,
                                         longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-839               BC101007.1         1-839
            840-977             AC012414.12        35374-35511
            978-1048            BC101007.1         840-910
            1049-1119           AC012414.12        43584-43654
            1120-1687           BC101007.1         911-1478
FEATURES             Location/Qualifiers
     source          1..1687
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q11.2"
     gene            1..1687
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /note="POTE ankyrin domain family member B2"
                     /db_xref="GeneID:100287399"
                     /db_xref="HGNC:HGNC:48327"
     exon            1..443
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..1668
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /note="POTE ankyrin domain family member B; ANKRD26-like
                     family B member 1; Prostate, ovary, testis-expressed
                     protein on chromosome 15"
                     /codon_start=1
                     /product="POTE ankyrin domain family member B2"
                     /protein_id="NP_001264232.1"
                     /db_xref="CCDS:CCDS59248.1"
                     /db_xref="GeneID:100287399"
                     /db_xref="HGNC:HGNC:48327"
                     /translation="MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVG
                     TSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRRED
                     LDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRC
                     QLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMA
                     KALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAV
                     CCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSE
                     NSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGL
                     PENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTG
                     ISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKH
                     QNQLRENKILEEIESVKEKLLKTIQLNEEALTKTSI"
     exon            444..558
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            559..732
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            733..839
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            840..977
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1048
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1119
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1120..1164
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1165..1331
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1332..1455
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1687
                     /gene="POTEB2"
                     /gene_synonym="POTE-15; POTEB"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctactaccgg cctcccctgg ctgttaaaag cagatggtgg ctgaggtttg ttcaatgccc
       61 gctgcctctg ctgtgaagaa gccatttgat ctcaggagca agatgggcaa gtggtgccac
      121 caccgcttcc cctgctgcag ggggagcggc acgagcaatg tgggcacttc tggagaccat
      181 gacgactcct ttatgaagac actcaggagc aagatgggca agtggtgctg tcactgcttc
      241 ccctgctgca gggggagcgg caagagcaac gtgggcactt ggggagacta cgacgacagc
      301 gccttcatgg agccgaggta ccacgtccgt cgagaagatc tggacaagct ccacagagct
      361 gcctggtggg gtaaagtccc cagaaaggat ctcatcgtca tgctcaggga cactgacatg
      421 aacaagaggg acaagcaaaa gaggactgct ctacatttgg cctctgccaa tggaaattca
      481 gaagtagtac aactcctgct ggacagacga tgtcaactta acgtccttga caacaaaaaa
      541 aggacagctc tgataaaggc cgtacaatgc caggaagatg aatgtgtgtt aatgttgctg
      601 gaacatggcg ctgatggaaa tattcaagat gagtatggaa ataccgctct acactatgct
      661 atctacaatg aagataaatt aatggccaaa gcactgctct tatatggtgc tgatattgaa
      721 tcaaaaaaca agtgtggcct cacaccactt ttgcttggcg tacatgaaca aaaacaggaa
      781 gtggtgaaat ttttaatcaa gaaaaaagct aatttaaatg cacttgatag atatggaaga
      841 actgccctca tacttgctgt atgttgtgga tcagcaagta tagtcaatct tctacttgag
      901 caaaatgttg atgtatcttc tcaagatcta tctggacaga cagccagaga gtatgctgtt
      961 tctagtcatc atcatgtaat ttgtgaatta ctttctgact ataaagaaaa acagatgcta
     1021 aaaatctctt ctgaaaacag caatccagaa caagacttaa agctgacatc agaggaagag
     1081 tcacaaaggc ttaaagtcag tgaaaatagc cagccagaga aaatgtctca agaaccagaa
     1141 ataaataagg actgtgatag agaggttgaa gaagaaataa agaagcatgg aagtaatcct
     1201 gtgggattac cagaaaacct gactaatggt gccagtgctg gcaatggtga tgatggatta
     1261 attccacaaa ggaagagcag aaaacctgaa aatcagcaat ttcctgacac tgagaatgaa
     1321 gagtatcaca gtgacgaaca aaatgatacc cagaaacaac tttctgaaga acagaacact
     1381 ggaatatcac aagatgagat tctgactaat aaacaaaagc agatagaagt ggctgaaaag
     1441 gaaatgaatt ctgagctttc tcttagtcat aagaaagaag aagatctctt gcgtgaaaac
     1501 agcatgttgc gggaagaaat tgccaagcta agactggaac tagatgaaac aaaacatcag
     1561 aaccagctaa gggaaaataa aattttggag gaaattgaaa gtgtaaaaga aaaacttcta
     1621 aagactatac aactgaatga agaagcatta acgaaaacca gtatttaagt acagtggaca
     1681 gcttagg
//
