LOCUS       NM_001277304            2143 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens POTE ankyrin domain family member B (POTEB),
            transcript variant 1, mRNA.
ACCESSION   NM_001277304 XM_003846376
VERSION     NM_001277304.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2143)
  AUTHORS   Alkan,C., Kidd,J.M., Marques-Bonet,T., Aksay,G., Antonacci,F.,
            Hormozdiari,F., Kitzman,J.O., Baker,C., Malig,M., Mutlu,O.,
            Sahinalp,S.C., Gibbs,R.A. and Eichler,E.E.
  TITLE     Personalized copy number and segmental duplication maps using
            next-generation sequencing
  JOURNAL   Nat Genet 41 (10), 1061-1067 (2009)
   PUBMED   19718026
  REMARK    GeneRIF: Identifies POTEB as being one of 30 genes with the most
            variable copy numbers in three human genomes.
REFERENCE   2  (bases 1 to 2143)
  AUTHORS   Zody,M.C., Garber,M., Sharpe,T., Young,S.K., Rowen,L., O'Neill,K.,
            Whittaker,C.A., Kamal,M., Chang,J.L., Cuomo,C.A., Dewar,K.,
            FitzGerald,M.G., Kodira,C.D., Madan,A., Qin,S., Yang,X., Abbasi,N.,
            Abouelleil,A., Arachchi,H.M., Baradarani,L., Birditt,B., Bloom,S.,
            Bloom,T., Borowsky,M.L., Burke,J., Butler,J., Cook,A.,
            DeArellano,K., DeCaprio,D., Dorris,L. 3rd, Dors,M., Eichler,E.E.,
            Engels,R., Fahey,J., Fleetwood,P., Friedman,C., Gearin,G.,
            Hall,J.L., Hensley,G., Johnson,E., Jones,C., Kamat,A., Kaur,A.,
            Locke,D.P., Madan,A., Munson,G., Jaffe,D.B., Lui,A., Macdonald,P.,
            Mauceli,E., Naylor,J.W., Nesbitt,R., Nicol,R., O'Leary,S.B.,
            Ratcliffe,A., Rounsley,S., She,X., Sneddon,K.M., Stewart,S.,
            Sougnez,C., Stone,S.M., Topham,K., Vincent,D., Wang,S.,
            Zimmer,A.R., Birren,B.W., Hood,L., Lander,E.S. and Nusbaum,C.
  TITLE     Analysis of the DNA sequence and duplication history of human
            chromosome 15
  JOURNAL   Nature 440 (7084), 671-675 (2006)
   PUBMED   16572171
REFERENCE   3  (bases 1 to 2143)
  AUTHORS   Bera,T.K., Huynh,N., Maeda,H., Sathyanarayana,B.K., Lee,B. and
            Pastan,I.
  TITLE     Five POTE paralogs and their splice variants are expressed in human
            prostate and encode proteins of different lengths
  JOURNAL   Gene 337, 45-53 (2004)
   PUBMED   15276201
REFERENCE   4  (bases 1 to 2143)
  AUTHORS   Bera,T.K., Zimonjic,D.B., Popescu,N.C., Sathyanarayana,B.K.,
            Kumar,V., Lee,B. and Pastan,I.
  TITLE     POTE, a highly homologous gene family located on numerous
            chromosomes and expressed in prostate, ovary, testis, placenta, and
            prostate cancer
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16975-16980 (2002)
   PUBMED   12475935
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1462]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC183089.3.
            
            On Dec 4, 2019 this sequence version replaced NM_001277304.1.
            
            Transcript Variant: This variant (1) represents the longer variant
            and encodes the supported protein.
            
            CCDS Note: The exon combination of this CCDS representation is
            inferred based on highly similar paralogous transcript alignments,
            e.g., AY465170.1 or BC101005.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968968, SAMEA2148093
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000439682.2/ ENSP00000457689.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-899               AC183089.3         128856-129754
            900-1014            AC183089.3         134137-134251
            1015-1188           AC183089.3         134411-134584
            1189-1295           AC183089.3         137413-137519
            1296-1433           AC183089.3         138857-138994
            1434-1504           AC183089.3         141505-141575
            1505-1575           AC183089.3         147069-147139
            1576-1620           AC183089.3         148543-148587
            1621-1787           AC183089.3         149633-149799
            1788-1911           AC183089.3         158269-158392
            1912-2143           AC183089.3         160031-160262
FEATURES             Location/Qualifiers
     source          1..2143
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q11.2"
     gene            1..2143
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /note="POTE ankyrin domain family member B"
                     /db_xref="GeneID:100996331"
                     /db_xref="HGNC:HGNC:33734"
                     /db_xref="MIM:608912"
     exon            1..899
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     CDS             490..2124
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /note="protein expressed in prostate, ovary, testis, and
                     placenta 15; ANKRD26-like family B, member 1;
                     cancer/testis antigen family 104, member 5; prostate,
                     ovary, testis-expressed protein on chromosome 15; POTE
                     ankyrin domain family member B2"
                     /codon_start=1
                     /product="POTE ankyrin domain family member B"
                     /protein_id="NP_001264233.1"
                     /db_xref="CCDS:CCDS59250.1"
                     /db_xref="GeneID:100996331"
                     /db_xref="HGNC:HGNC:33734"
                     /db_xref="MIM:608912"
                     /translation="MVAEVCSMPAASAVKKPFDLRSKMGKWCHHRFPCCRGSGTSNVG
                     TSGDHDDSFMKTLRSKMGKWCCHCFPCCRGSGKSNVGTWGDYDDSAFMEPRYHVRRED
                     LDKLHRAAWWGKVPRKDLIVMLRDTDMNKRDKQKRTALHLASANGNSEVVQLLLDRRC
                     QLNVLDNKKRTALIKAVQCQEDECVLMLLEHGADGNIQDEYGNTALHYAIYNEDKLMA
                     KALLLYGADIESKNKCGLTPLLLGVHEQKQEVVKFLIKKKANLNALDRYGRTALILAV
                     CCGSASIVNLLLEQNVDVSSQDLSGQTAREYAVSSHHHVICELLSDYKEKQMLKISSE
                     NSNPEQDLKLTSEEESQRLKVSENSQPEKMSQEPEINKDCDREVEEEIKKHGSNPVGL
                     PENLTNGASAGNGDDGLIPQRKSRKPENQQFPDTENEEYHSDEQNDTQKQLSEEQNTG
                     ISQDEILTNKQKQIEVAEKEMNSELSLSHKKEEDLLRENSMLREEIAKLRLELDETKH
                     QNQLRENKILEEIESVKEKLLKTIQLNEEALTKTSI"
     exon            900..1014
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1188
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1295
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1433
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1504
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1575
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1576..1620
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1621..1787
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1911
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2143
                     /gene="POTEB"
                     /gene_synonym="A26B1; CT104.5; POTE-15; POTE15; POTEB2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcgcgcc ccgcacgcgc gcccccgcac gcgcataacg gcttggctta cctgtaacgg
       61 gtacgcttcg cttcgcgttc ctcgcttggc cttgcgttcc tagcttggct tggctgttag
      121 tagctttgcc tggtgtttct tgcttggatt ggcgtttcct ccctcgcatt cctttgctgg
      181 acttgacctt ttctctgctg ggtttggcat tcccttgact gggctgggtg tttccttggg
      241 agggggggct tggcctttcc tggggtgggc gtggggtccc cctggtgggc gtgggctttc
      301 cccgggtggg tgtgggtttt ccctgggtgg ggtgggctgg gctcccttgc tggggttggc
      361 aagttttggc tgggattgac ctttctcttc aaacagattg gaaacccagg gtttcctgct
      421 agttggtgaa actggttggt agacgcgatc tgttcgctac taccggcctc ccctggctgt
      481 taaaagcaga tggtggctga ggtttgttca atgcccgctg cctctgctgt gaagaagcca
      541 tttgatctca ggagcaagat gggcaagtgg tgccaccacc gcttcccctg ctgcaggggg
      601 agcggcacga gcaatgtggg cacttctgga gaccatgacg actcctttat gaagacactc
      661 aggagcaaga tgggcaagtg gtgctgtcac tgcttcccct gctgcagggg gagcggcaag
      721 agcaacgtgg gcacttgggg agactacgac gacagcgcct tcatggagcc gaggtaccac
      781 gtccgtcgag aagatctgga caagctccac agagctgcct ggtggggtaa agtccccaga
      841 aaggatctca tcgtcatgct cagggacact gacatgaaca agagggacaa gcaaaagagg
      901 actgctctac atttggcctc tgccaatgga aattcagaag tagtacaact cctgctggac
      961 agacgatgtc aacttaacgt ccttgacaac aaaaaaagga cagctctgat aaaggccgta
     1021 caatgccagg aagatgaatg tgtgttaatg ttgctggaac atggcgctga tggaaatatt
     1081 caagatgagt atggaaatac cgctctacac tatgctatct acaatgaaga taaattaatg
     1141 gccaaagcac tgctcttata tggtgctgat attgaatcaa aaaacaagtg tggcctcaca
     1201 ccacttttgc ttggcgtaca tgaacaaaaa caggaagtgg tgaaattttt aatcaagaaa
     1261 aaagctaatt taaatgcact tgatagatat ggaagaactg ccctcatact tgctgtatgt
     1321 tgtggatcag caagtatagt caatcttcta cttgagcaaa atgttgatgt atcttctcaa
     1381 gatctatctg gacagacagc cagagagtat gctgtttcta gtcatcatca tgtaatttgt
     1441 gaattacttt ctgactataa agaaaaacag atgctaaaaa tctcttctga aaacagcaat
     1501 ccagaacaag acttaaagct gacatcagag gaagagtcac aaaggcttaa agtcagtgaa
     1561 aatagccagc cagagaaaat gtctcaagaa ccagaaataa ataaggactg tgatagagag
     1621 gttgaagaag aaataaagaa gcatggaagt aatcctgtgg gattaccaga aaacctgact
     1681 aatggtgcca gtgctggcaa tggtgatgat ggattaattc cacaaaggaa gagcagaaaa
     1741 cctgaaaatc agcaatttcc tgacactgag aatgaagagt atcacagtga cgaacaaaat
     1801 gatacccaga aacaactttc tgaagaacag aacactggaa tatcacaaga tgagattctg
     1861 actaataaac aaaagcagat agaagtggct gaaaaggaaa tgaattctga gctttctctt
     1921 agtcataaga aagaagaaga tctcttgcgt gaaaacagca tgttgcggga agaaattgcc
     1981 aagctaagac tggaactaga tgaaacaaaa catcagaacc agctaaggga aaataaaatt
     2041 ttggaggaaa ttgaaagtgt aaaagaaaaa cttctaaaga ctatacaact gaatgaagaa
     2101 gcattaacga aaaccagtat ttaagtacag tggacagctt agg
//
